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August 29, 2025 49 mins

Understanding the root causes behind Autistic burnout symptoms can feel confusing, especially when physical symptoms are present but dismissed or misunderstood. Many in the neurodivergent community face not only emotional exhaustion but a web of hidden medical conditions that often go undiagnosed, leaving them searching for seemingly elusive answers and support.

In this episode, Patrick Casale and Dr. Megan Anna Neff, two AuDHD mental health professionals, are joined by Dr. Mel Houser, an Autistic physician and founder of All Brains Belong, as they discuss the intricate connections between Autistic burnout and underlying health issues like mitochondrial dysfunction, post-exertional malaise (PEM), dysautonomia, postural orthostatic tachycardia syndrome (POTS), and mast cell activation. This discussion covers what happens on a cellular level during burnout, the importance of pacing and sensory adjustments, and why diagnostic overshadowing can be such a serious barrier to effective care. Dr. Houser also shares practical strategies, resources, and hopeful ways forward for those struggling with chronic fatigue, energy regulation, and co-occurring medical concerns.

Top 3 reasons to listen to the entire episode:

  1. Gain a deeper understanding of why Autistic burnout isn’t "just in your head"—this episode breaks down the science behind energy production, chronic illness, and how they intersect with neurodivergent experiences.
  2. Discover pacing techniques, environmental adaptations, and supplements that may support recovery and energy management—plus get direct links to free resources designed specifically for neurodivergent adults.
  3. Hear honest, validating conversation about grief, privilege, and agency while exploring what it really takes to honor energy access needs and navigate medical systems as an Autistic or ADHD adult.

If you or someone you care for battles constant exhaustion, brain fog, or unexplained physical symptoms, don’t miss this compassionate and practical conversation, and learn how Autistic burnout and chronic illness connect—and discover steps you can take to better support your body, brain, and well-being.

DISCLAIMER: This episode is not intended as medical advice.

More about Mel:

Dr. Mel Houser (she/they) is an Autistic family physician with a clinical focus on providing primary care for neurodivergent patients across the lifespan. She is the Founder and Executive Director of All Brains Belong VT, a nonprofit 501(c)(3) organization in Montpelier, Vermont that uses universal design principles to provide neurodiversity-affirming medical care, social connection opportunities for all ages, and neurodiversity-related educational training. At age 37, Dr. Houser was diagnosed as autistic, ADHD, dyspraxic, dyslexic, and dyscalculic. She is also the parent of an autistic 6-year-old, who is her guru of so many keys to the universe.


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