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June 24, 2025 72 mins

Investigative journalist Charles Piller explains the remarkable story of fraud he has uncovered in Alzheimer’s Disease research, which he discusses in a new book: Doctored: Fraud, Arrogance and Tragedy in the Quest to Cure Alzheimer’s. Charles argues the result of this is that Alzheimer’s research and treatment has been set by years - if not decades.

He goes on to discusse the trial data on which several Alzheimer’s drugs, including Aducanumab, Lecanemab and Donanemab, were approved. Charles says the data is unconvincing and  the side effects – including brain swelling and bleeding -  concerning.

Doctored: Fraud, Arrogance and Tragedy in the Quest to Cure Alzheimer’s by Charles Piller is published by Icon Books.

Charles Piller is an investigative journalist who works for the journal Science. His work has also been published in a number of other publications including The New York Times and the Los Angeles Times. Charles has won a number of journalism awards for his work and is also the author of the books Gene Wars and The Fail-Safe Society.

If you would like to support this podcast you can do so via Patreon at or via PayPal.

The host of the podcast, Liz Tucker is an award winning medical journalist and former BBC producer and director.  You can follow Liz on X and read further information about the podcast on her Substack newsletter.

Medical Matters with Liz Tucker has been selected by Feedspot as one of the top 15 UK Medical Podcasts https://blog.feedspot.com/uk_medical_podcasts/

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