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September 16, 2025 34 mins

AI or rules, what really wins in Amazon PPC? Uncover the truth about Amazon ads automation, smarter bidding, and scaling Amazon strategies sellers need to know today.

► Instagram: instagram.com/serioussellerspodcast

► Free Amazon Seller Chrome Extension: https://h10.me/extension

► Sign Up For Helium 10: https://h10.me/signup  (Use SSP10 To Save 10% For Life)

► Learn How To Sell on Amazon: https://h10.me/ft

► Watch The Podcasts On YouTube: youtube.com/@Helium10/videos

Curious about how AI and Rules can revolutionize your Amazon advertising strategy? Imagine harnessing the power of emerging AI tools to supercharge your PPC campaigns and keep your brand ahead of the competition. Join us as Destaney Wishon shares her expertise on striking the perfect balance between AI, automation, and rule-based approaches to unlock the full potential of your Amazon advertising efforts.

Our conversation takes an insightful turn as we explore the complexities of managing advertising campaigns for brands with intricate SKU lines and varied objectives. Destaney unpacks the nuances of using AI and rules-based systems, revealing how to leverage these tools without losing sight of your brand's unique insights and goals. We get into the importance of contextual understanding when evaluating key metrics like ACoS, ensuring that your strategies align with your specific product types and campaign goals. Plus, uncover the trade-offs between automation and manual control, and learn how agencies can enhance operational efficiency while maintaining that all-important personal touch.

But that's not all. We offer a comprehensive guide to optimizing your advertising strategies with Amazon Marketing Cloud (AMC) and audience targeting techniques. You'll learn how to use Helium 10 Ads to set up AMC instances and discover practical tips for building profitable audience segments. From increasing your Return on Advertising Spend (ROAS) to avoiding campaign cannibalization, we equip you with the tools and insights necessary to thrive in a competitive Amazon marketplace. To top it off, we invite you to subscribe to the Serious Sellers Podcast’s new YouTube channel for a chance to win a one-on-one session with either Carrie, Bradley, or Shivali, offering personal insights and a unique opportunity to enhance your advertising game.

In episode 701 of the Serious Sellers Podcast, Carrie and Destaney discuss:

  • 00:59 - AI vs Automation in Amazon Advertising
  • 06:47 - Optimizing AI for Different Goals 
  • 09:30 - Advanced Strategies for Amazon Advertising
  • 10:14 - Interpreting ACoS for Amazon PPC Success 
  • 15:53 - AI vs. Keyword Harvesting in Marketing
  • 18:38 - Importance of Video in Amazon Advertising
  • 22:37 - Strategies for Amazon Ad Console
  • 31:23 - Optimizing PPC Campaigns for Improved ROAS
  • 34:24 - Engagement Incentives for Video Viewers
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