- Wendy Dean (Episode 170): Physician, host of 43cc podcast, Moral Matters podcast, author of If I Betray These Words: Moral Injury in Medicine and Why It's So Hard for Clinicians to Put Patients First and founder of Moral Injury in Healthcare.
- Wendy Schiller (Episode 160): Brown University’s Interim Director of the Watson Institute for International and Public Affairs, Director of the Taubman Center for American Politics and Policy, and co-author of Inequality Across State Lines
- Joanna McClinton (Episode 164): Attorney, politician and 143rd Speaker of the House of Representatives for the State of Pennsylvania
- Rob Gore (Episode 173): Physician, author ofTreating Violence: An Emergency Room Doctor Takes on a Deadly American Epidemic, and founder of KAVI the Kings Against Violence Initiative
- Thea James (Episode 133): Physician, Vice President of Mission and Associate Chief Medical Officer at Boston Medical Center, featured in Faces of Medicine docuseries by Khama Ennis.
- Pooja Kumar (Episode 169): Physician and senior partner McKinsey & Company and leader in the McKinsey Health Institute.
- Joe Saul-Sehy (Episode 141): Personal finance expert, co-author of Stacked: Your Super-Serious Guide to Modern Money Management, and host of Stacking Benjamins Show
- Valerie Jarrett (Episode 136): CEO of The Obama Foundation, and author of Finding My Voice: My Journey to the West Wing and the Path Forward.
- Graham Walker (Episode 175): Physician, HealthTech visionary, co founder of MDCalc, the NNT, the Physicians' Charter for Responsible AI, and OffCall, and host of How I Doctor podcast
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