CRISPR

Discover how CRISPR gene editing is leaping from research labs into real-world medicine and engineering. Ryan Cole unpacks the science, logistics, and innovation behind approved therapies, in-body delivery breakthroughs, and next-generation editing tools transforming what's possible at scale. For more content like this, visit QuietPlease.ai This show includes AI-generated content.

Episodes

CRISPR - Uncover the future of genetic editing with Ryan Cole

April 10, 2026 • 41 secs

Join host Ryan Cole as he cuts through the CRISPR hype to reveal what's actually happening in labs and clinics. From the first approved gene-editing cure to the engineering challenges of editing DNA in living patients, this series explores the gap between promise and practice in genetic medicine.

Loved this episode? Discover more original shows from the Quiet Please Network at QuietPlease.ai, explore our curated favorites here amzn....

Listen

Watch

Mark as Played

Transcript

CRISPR - Beyond Cut and Break: New Toolkits for Large-Scale Genome Engineering

April 10, 2026 • 26 mins

Ryan Cole explores how CRISPR evolved from simple gene-cutting scissors into a sophisticated genome engineering workshop. From MIT's PASTE technology inserting DNA base pairs to CRISPR-recombinase hybrids enabling one-step gene replacement, Cole examines breakthrough tools reshaping genetic medicine and the gap between laboratory capabilities and patient deployment.

Loved this episode? Discover more original shows from the Quiet Ple...

Listen

Watch

Mark as Played

Transcript

CRISPR - Editing Inside the Body: The Engineering Challenge of In Vivo Delivery

April 10, 2026 • 27 mins

Host Ryan Cole explores CRISPR's biggest challenge: delivery. While gene editing is proven, safely getting edits into patients remains medicine's hardest problem. Cole examines viral vectors versus lipid nanoparticles, breakthrough trials for blindness and liver disease, and why delivery methods determine which diseases we can treat.

Loved this episode? Discover more original shows from the Quiet Please Network at QuietPlease.ai, ex...

Listen

Watch

Mark as Played

Transcript

CRISPR - From Trial to Pharmacy Shelf: Scaling the First Gene-Editing Cure

April 10, 2026 • 26 mins

Ryan Cole examines Casgevy, the world's first approved CRISPR medicine for sickle cell disease and beta thalassemia. While revolutionary, delivering this autologous gene therapy faces massive challenges: a $2.2 million price tag, months-long manufacturing, only 50 global treatment centers, and access barriers in regions with highest disease burden.

Loved this episode? Discover more original shows from the Quiet Please Network at Qui...

Listen

Watch

Mark as Played

CRISPR - From Trial to Pharmacy Shelf: Scaling the First Gene-Editing Cure

April 10, 2026 • 26 mins

Listen

Watch

Mark as Played

Transcript

Popular Podcasts

Las Culturistas with Matt Rogers and Bowen Yang

Ding dong! Join your culture consultants, Matt Rogers and Bowen Yang, on an unforgettable journey into the beating heart of CULTURE. Alongside sizzling special guests, they GET INTO the hottest pop-culture moments of the day and the formative cultural experiences that turned them into Culturistas. Produced by the Big Money Players Network and iHeartRadio.

Dateline NBC

Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

Stuff You Should Know

If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

The Breakfast Club

The World's Most Dangerous Morning Show, The Breakfast Club, With DJ Envy, Jess Hilarious, And Charlamagne Tha God!

Crime Stories with Nancy Grace

Nancy Grace dives deep into the day’s most shocking crimes and asks the tough questions in her new daily podcast – Crime Stories with Nancy Grace. Nancy Grace had a perfect conviction record during her decade as a prosecutor and used her TV show to find missing people, fugitives on the run and unseen clues. Now, she will use the power of her huge social media following and the immediacy of the internet to deliver daily bombshells! Theme Music: Audio Network

Advertise With Us

CRISPR

Episodes

.css-14f5ked{margin:0;word-break:break-word;display:-webkit-box;-webkit-box-orient:vertical;box-orient:vertical;-webkit-line-clamp:2;overflow:hidden;}CRISPR - Uncover the future of genetic editing with Ryan Cole

.css-r6mb8g{margin:0;word-break:break-word;display:-webkit-box;-webkit-box-orient:vertical;box-orient:vertical;-webkit-line-clamp:1;overflow:hidden;}CRISPR - Beyond Cut and Break: New Toolkits for Large-Scale Genome Engineering

CRISPR - Editing Inside the Body: The Engineering Challenge of In Vivo Delivery

CRISPR - From Trial to Pharmacy Shelf: Scaling the First Gene-Editing Cure

CRISPR - From Trial to Pharmacy Shelf: Scaling the First Gene-Editing Cure

Popular Podcasts

CRISPR - Uncover the future of genetic editing with Ryan Cole

CRISPR - Beyond Cut and Break: New Toolkits for Large-Scale Genome Engineering