Episode Transcript
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Speaker 1 (00:00):
Welcome back listeners to Navigating Ozepic, the podcast where we
break down the most important news and insights about ozepic.
As of today, July twenty sixth, twenty twenty five, there
have been several developments on the medical, scientific, and policy
fronts that are shaping how this medication is discussed and understood.
Whether you are a patient, a caregiver, or just curious
(00:23):
about the broader health implications, Today's episode is packed with
timely updates. Let's jump in with an intriguing advance in
the research on the neurological benefits of a zepic and
other drugs in its class, known as GLP one receptor agonists.
According to new coverage by Cytec Daily, just published, scientists
have found a measurable reduction in stroke risk for people
(00:44):
taking these medications. They note that ozepic does not merely
help manage diabetes and control appetite. It also seems to
offer a protective benefit for the brain, potentially improving recovery
outcomes after stroke. This builds on a growing body of
studies indicating that gie LP one agonists, beyond their effects
on blood sugar and weight loss, might have far reaching
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impacts on the vascular and neurological health of patients. Similarly,
a recent report in Medical News Today summarizes a new
study from the Journal of Alzheimer's Disease highlighting that semaglutide,
the active ingredient in ozepic, may help lower the risk
of dementia in people with type two diabetes. Researchers analyze
the health data of over one point seven million adults
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and found that those prescribe semaglutide experienced fewer new cases
of dementia over three years. The study's lead author explains
that the benefit likely comes from semaglutide's ability to target
multiple dementia risk factors at once, diabetes, obesity, and inflammation.
This is particularly promising given the lack of curative treatments
for dementia and the high global burden of the disease.
(01:51):
Switching to mental health and addiction research, the Brain and
Behaviourist Diabetes Research Foundation recently reported on a preliminary clinical
trial showing that semaglutide may decrease heavy drinking and cravings
in people with alcohol use disorder. In this small scale,
nine week trial, participants who were not actively seeking treatment
for drinking still experienced reduced alcohol consumption and fewer days
(02:14):
of heavy drinking. This underscores the potential for repurposing Ozepic
and similar medications for broader neuropsychiatric indications. However, experts caution
that much larger and longer studies are required before any
changes to medical guidance or prescribing practices are considered. Still,
these early signals are intriguing and signal an era of
(02:35):
novel applications for medications initially intended for diabetes. Of course,
alongside headline grabbing benefits, the question of side effects and
long term risks remains front and center, as discussed in
several forums, including a recent piece in the gill University's
Office for Science and Society. Scrutiny has turned to rare
but serious adverse events. For example, there has been ongoing
(02:58):
debate about whether medications like ozepic are linked to a
rare form of sudden onset blindness called non arturitic anterior
ischemic optic neuropathy. Doctors in the United States diagnose about
six thousand cases annually, so it remains a rare outcome.
The handful of available studies disagree on whether the risk
meaningfully increases with semi blue tide use, and current databases
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are not complete enough to settle the question. Experts conclude
that while the risk is extremely rare, regulators are remaining
cautious and further research is ongoing. A second major topic
in the news is the pattern of weight regain after
stopping drugs. Like A zenpic Science alert summarizes a recent
meta analysis published in BMC Medicine. Most people who discontinue
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GLP one medications will begin to regain weight within about
eight weeks, and this regain can continue for months. The
review encompassed eleven clients medical trials and found that the
rebound is not just an issue with semi blue tide,
but also with other weight management medications as well as
surgical alternatives like gastric bypass. The team notes that the
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exact reasons for persistent weight regain are still unclear, and
longer term studies are needed to pass out the biological
and psychological dynamics at play. The Independent similarly reported that
participants commonly regained a significant portion of lost weight after
stopping treatment, with differences depending on which medication was used
and the participants lifestyle changes during and after therapy. This
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brings up important questions for doctors and patients about the
sustainability of medication assisted weight loss and what kinds of
ongoing support are needed. You may have seen social media
buzzing with personal stories of food cravings, appetite changes, or
even changes in mood after starting or stopping ozepic. Recent
coverage by Medical Express underscores that GLP one drugs work
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not only in the body, but also directly affect the
brain's reward and hunger centers. People with binge eating disorder
or those prone to compulsive eating report that intrusive thoughts
about food can decrease on ozepic, suggesting a dampening of
food noise. However, mental health professionals warn that these medications
are not yet proven as a stand alone treatment for
(05:09):
binge eating disorder or other eating disorders, and discontinuing them
can reverse these effects. The takeaway for listeners is that
while these medications reshape both body and mind, they should
be used thoughtfully, ideally as part of a comprehensive approach
to health. On the policy and access front, affordability continues
to be a challenge. For example, Arizona's medicaid program has
(05:31):
made headlines through Your Valley, highlighting that drugs like ozepic
remain inaccessible for many adults unless they have a formal
type two diabetes diagnosis. With high out of pocket costs
and continued demand, questions about equity and sustainable access will
only intensify as the use of GLP one medicaid