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July 12, 2025 5 mins
# Ozempic's Latest Research Reveals Unexpected Risks and Benefits - Navigating Ozempic Podcast

Discover breaking news about Ozempic and weight loss medications in this comprehensive episode of Navigating Ozempic. We analyze groundbreaking research from Nature Medicine highlighting both the benefits and concerning side effects of GLP-1 medications, including increased risks of kidney problems, pancreatitis, and arthritis. Learn why 30% of users abandon treatment within just four weeks and what this means for long-term health outcomes.

The episode explores emerging applications beyond diabetes and obesity, featuring new studies on heart health, cognitive function, and mental wellbeing. We also discuss alarming research linking these medications to disordered eating behaviors in young men—a demographic often overlooked in eating disorder conversations.

Special coverage includes Lizzo's candid revelation about her Ozempic experience and important context about ongoing research at Touro University Nevada examining connections between GLP-1 medications, gut microbiome health, and neurological disease risk factors.

Whether you're considering Ozempic treatment, currently using weight loss medications, or simply staying informed about this pharmaceutical phenomenon, this episode provides essential information about the evolving science and cultural impact of these increasingly popular drugs.

#Ozempic #WeightLossMedications #OzempicResearch #GLP1Medications #WeightLossJourney #OzempicSideEffects #MedicalResearch

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Episode Transcript

Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:00):
Welcome back to Navigating Ozempic, the podcast dedicated to bringing
listeners up to minute news, research, and real life stories
about one of the most talked about medications on the planet.
We are here to help you make sense of the
latest developments in the world of ozempic, from its medical
breakthroughs to its sometimes controversial impact on lifestyle, health and culture.

(00:20):
The past three days have brought a wave of new findings,
major headlines, and candid celebrity admissions surrounding ozepic and similar medications.
Let us start with the surge and new research which
is quickly changing what we know about these drugs. A
principal story comes from a recent large scale study published
in Nature Medicine at the beginning of this year, but
making renewed headlines this week as results continue to be

(00:43):
analyzed and discussed. Over two hundred and fifteen thousand people
using ozempic and other medications in its drug class were
systematically evaluated, with researchers mapping every reported health risk tied
to this new generation of treatments. According to Discover magazine,
the researchers found not only confirmed benefits for diabetes and obesity,
but also unattested risks, especially with long term use, while

(01:07):
ozepic is proving effective for weight loss and even improved
mental health for some patients. The study identified increased rates
of kidney problems, pancreatitis, and arthritis, among other adverse events.
The risk of pancreatitis in particular was found to be
notably higher, with some cases resulting in fatal outcomes. Medical
professionals are emphasizing that serious side effects such as acute pancreatitis,

(01:30):
which is a dangerous inflammation of the pancreas, have been
linked to at least ten deaths in the United Kingdom alone.
Penny Ward, a clinical pharmacologist at King's College London, noted
that it is typical for new side effects to emerge
only after a medication is widely used, as clinical trials
frequently involve fewer people than the real world does. That
is why both patients and providers are being urged to

(01:52):
consider the full range of possible risks, not just the
immediate benefits. Ozenpic, which is also sold under the name Wagovi,
was as initially green lit by the regulatory authorities for
type two diabetes and later for weight loss. Common side
effects such as nausea diarrhea, and vision changes have become
so widespread that casual phrases like ozepic face or ozepic

(02:14):
butt now describe some of the cosmetic effects of rapid
weight loss, such as unwonted sagging of the skin. However,
reports are mounting about more serious complications, including musculo skeletal problems,
blood pressure drops leading to dizziness or fainting, kidney stones,
and kidney inflammation. A notable trend uncovered by Blue Health Intelligence,

(02:35):
a healthcare data analytics firm, is that thirty percent of
users stop taking ozepic after only four weeks, often before
the drug can even begin to provide meaningful health improvements.
Part of this high dropout rate is believed to be
due to the severity of side effects or unmet expectations
regarding rapid, effortless weight loss. On the approval and application front,

(02:56):
there is a growing movement in both the media and
medicine to expand zepics used beyond diabetes and obesity. Science
Line reports that some researchers are optimistic about the potential
of these medications to improve heart health, cognitive function, and
even mental well being. Yet this wave of enthusiasm is
being met with skepticism. Some experts caution that the rush

(03:17):
to find new uses for ozepic may be driven more
by commercial interests than genuine medical need, raising questions about
whether patient welfare is always at the forefront of these studies.
Concerns are not limited to physical side effects. A new
study covered in Medical Express has identified a troubling link
between the use of prescription weight loss medications like ozepic

(03:38):
and disordered eating behaviours among boys and young men. The research,
which surveyed more than fifteen hundred males aged fifteen to
thirty five in Canada and the United States, found that
those using weight loss medications reported significantly higher rates of
binge eating, purging, and a feeling of loss of control
around food compared to non users. These findings spotlight the

(04:00):
psychological and social ramifications of a drug that is increasingly
marketed to broader populations, including groups historically left out of
eating disorder conversations. On a related note, there is ongoing
research at Toro University, Nevada, which is actively seeking volunteers
for a long term study on how injectable medications like
ozepic impact the GOT microbiome, as well as risk factors

(04:24):
for neurological diseases such as Alzheimer's and Parkinson's. The study
requires participants to commit to regular blood and stool samples
over two years and is expected to provide new insights
into how these drugs affect not just weight or appetite,
but also overall brain and gut health. As doctor Raekash Singh,
who is leading the research, pointed out, these medications often

(04:46):
require lifetime treatment, but we are only beginning to understand
the long term effects on the body. The cultural conversation
around ozempic continues to be shaped by high profile stories
and public figures. This week, musician and body positivity icon
Lizzo broke her silence about her own experience using ozempic
on the Just Trish podcast. Lizzo revealed that she turned

(05:06):
to the drug after extensive efforts to manage her weight
through other means. She was candid about the impact. While
azempic helped her feel full faster, she was careful to
clarify that the medication was just one small part of
her transformation. According to Lizzo, medication alone was unsustainable and
her journey ultimately required hard work, balanced lifestyle changes, and
ongoing dedication. Lizzo's openness is sparking an important dialogue about

(05:30):
the limitations of so called miracle drugs and the continuing
stigma around body image and weight in society. For anyone
considering starting
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