Episode Transcript
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Speaker 1 (00:00):
Welcome back to Navigating Ozempic, the podcast where we illuminate
the latest news and research on ozempic, from its evolving
medical applications to the ways it continues to shape everyday
health and wellness. Today is August second, twenty twenty five.
Let's dive straight into what's making headlines about azempic over
the past seventy two hours. Perhaps the most headline grabbing
(00:23):
development right now is on the legal front. According to
the Lawsuit Information Center, new lawsuits continue to be filed
against ozempic and other glucagin like peptide IE receptor agonists.
Plaintiffs allege severe gastro ingestitues associated with these medications. Just yesterday,
an update arrived on the litigation. Thousands of cases are
(00:44):
in play, and critical evidentiary hearings about expert testimony on
causation are scheduled through this fall and inter January of
next year, with expert reports now due through August and
final legal breasts wrapping up in January twenty twenty six.
The wheels of justice are turning slowly, and many experts
expect these lawsuits to be a year's long unfolding saga.
(01:06):
If you're following the ozepic legal story. Don't expect swift resolution,
but do expect ongoing scrutiny of safety, especially around gastro
intestinal side effects. One area of scientific concern that continues
to attract attention is the impact of ozempic and drugs
like it on lean muscle mass. Medical News Today published
(01:26):
a detailed summary just yesterday, highlighting that along with the
rapid loss of fat, some users experience significant muscle loss
while on ozepic. Although ozepic is food and drug administration
approved for type two diabetes in certain populations, its off
label use for weight loss remains common. The report notes
that lean mass losses of up to forty percent have
(01:48):
been observed with semaglutide, the main ingredient in ozepic, though
results vary for listeners using ozepic for weight or glucose control.
Experts openly advise maintaining regular exercise, is sates and sufficient
protein intake to protect muscle and preserve bone health during
rapid weight reduction. This challenge is particularly vital in light
(02:08):
of news from the Independent and the journal BMC Medicine
this week. A fresh review of eleven major clinical trials
confirms that patients who stop ozempic or its higher dose
cousin weggovy, can begin regaining lost weight within just eight
weeks after discontinuation, with the trend sustaining for approximately twenty
weeks before stabilizing. Studies controlled for differences in medication, diabetes status,
(02:31):
and lifestyle adjustments, yet the pattern of weight regain was
remarkably consistent. Unless significant lifestyle changes are locked in, much
of the weight can return, sometimes quite quickly. Researchers stress
that this rebound effect adds to the importance of making
long term behavior changes rather than relying solely on pharmaceutical intervention.
(02:52):
Though clinical results for ozempic's weight loss potential are well known,
new real world studies, as reported by drugs dot Com,
reveal ill more tempered effectiveness. Whereas clinical trials sometimes tout
average losses of fifteen to sixteen percent of body weight
for semaglutide, actual reductions among patients in real world settings
range from just two to eight percent after a year,
(03:14):
and only about a third of patients see losses greater
than five percent. The gap is driven by high discontinuation
rates and less than perfect adherents, which underscores that medication
is only part of a successful long term weight strategy.
Alongside these medical and lifestyle concerns is a fresh burst
of interest from the supplement market. According to an August
(03:34):
first piece from Harvard's th H. Chan School of Public Health,
the popularity of ozepic and similar medications has inspired an
onslaught of GLP one supplements, But as the report stresses,
there is little to no evidence that these over the
counterproducts deliver the same effects as prescription medications. T He
experts from Harvard strongly cautioned that these supplements may not
(03:57):
be safe or effective. They are not rigorously f D tested,
and their active ingredients might not be biologically relevant or
even absorbed by the human body in meaningful quantities. If
you are considering a supplement as a stand in for
prescription therapy, it's wise to check with a healthcare professional.
A major point of discussion this week comes out of
(04:17):
new findings reported by Pharmacy Times. Excitingly, a trio of
new studies presented at the Society of neuro Interventional Surgeries
Annual meeting have revealed that golp IE receptor agonists like
summerglutide may be able to reduce the impact of strokes
and improve outcomes in brain injuries. The University of Wisconsin
(04:38):
and University of Texas Medical Branch studies followed patients who
used these medications and suffered from strokes or brain hemorrhages,
finding a reduced risk of cognitive issues, future strokes, seizures,
and even death among users. While the data is still
preliminary and more research is needed to confirm these results,
these findings hinted a promising new frontier. Ozepic and related
(05:01):
drugs might one day be prescribed not just for diabetes
or obesity, but also as part of stroke prevention and
recovery protocols. Switching gears, it is worth highlighting a very
human impact in the world of lifestyle and self perception.
ABC News recently profiled a woman who sought a facelift
to remedy what is becoming known as a zepic face,
(05:24):
that is loose facial skin and a more gaunt appearance
following rapid weight loss from the drug. As this type
of cosmetic concern rises with a zempic's popularity, doctors and
esthetic clinics are reporting increased demand for procedures aiming to
counteract these changes from legislative corridors. Policy news arrive just
(05:45):
this week via The Independent, The federal government is considering
expanding Medicare and Medicaid coverage for a zepic when prescribed
for weight loss. This marks the considerable policy shift, as
coverage until now has been largely restricted to diabetes care.
The props