August 29, 2025 • 10 mins
The San Francisco 49ers enter the 2025 NFL season with one goal — get back to the Super Bowl. But with key roster changes, a challenging schedule, and the NFC gunning for them, can they maintain their dominance? In this video, we break down the 49ers' full 2025 schedule week-by-week, predict every win and loss, and analyze how their offense and defense stack up against the competition. From divisional battles to primetime matchups, we cover it all.
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#49ers #FTTB #NFL #NFLNews #PigskinPundits
Subscribe, hit the like button, and join us live Monday - Friday at 9 PM EST for Man Hour NFL Talk — a live, interactive show where your comments drive the conversation.
#49ers #FTTB #NFL #NFLNews #PigskinPundits
Mark as Played
Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:00):
De Francisco forty nine ers guys at semransix four nineers
in their two thousand and twenty five season with a
lot of buzz. But after some offseason shake up, some injuries,
my outlooks have shifted quite a bit on the San
Francisco forty Hinders guys. Just three months ago, I had
the Niners of the fourteen win powerhouse team. I had
them running the NFC West. I had them going potentially
(00:20):
to the two Super Bowl. I had them dominating a
lot of these games. Arguably one of the best teams
in the NFL. But since then a lot of things
have changed. Deebo Samuel no longer a San Francisco forty
nine Ers. He is out traded to the Commanders. Christian McCaffrey.
Injuries are starting to pack up yet again. Brandon Ayuk
(00:42):
probably won't even be back till October or November at
this particular time. Right, the wide receiver room fields like
a game of musical chairs. Every time you turn it
is the signing of a ride receiver here firing this guy,
releasing this guy, like it is just a circle of
we don't know what to do with our hands. In
San Francisco, as of right now. It is tough, right,
(01:04):
it is very, very tough. But with all these factor
guys tempered the optimism, temper the optimism guys. But so
let's break down the Sanisco for its twenty twenty five
schedule game by a game with the win lost prediction.
I think weeks one through five, guys, they start out rocky.
I think it is a rocky if you are San
Francisco for four to forty nine fan. Because week one,
(01:25):
they travel to Seattle to take on the Seahawks, and
they start to see them off at a loss on
the road, a loud environment, a hostile Seattle crowd, new
quarterback nice, rookie receiver Devas is coming back, leading to
doom two point zero. The Niagos struggle to find rhythm
and they drop with the home opener That is tough, sorry,
the road opener. Week number two, they're back on the
(01:48):
road yet again, taking on the New Orleans Saints. This
ton of team bounces back with a solid road win
over the Saints, guys showing flashes of their old dominance.
Now let's not get crazy, because in in the end,
it is New Orleans Saints. In the end, New Orleans
States are going to be one of the worst teams
in the NFL. In the end, the Orleans Saints Kobe
gonna have the number one overall pick. Drafting arch maning.
(02:08):
Let's just call it spades be at the end of
the day. But Week three, finally the home opener, the
Arizona Cardinals coming to San Francisco could candle light Levi
Stadium whatever you want to call it. A tough divisional
battle ends and heartbreak at home. The Cardinals are just
a sneaky good team this season. Guys, do not sleep
on the Cardinals, but give them another loss. But then
(02:29):
finally back at home yet again, take on the Jacksonville Jaguars.
This time, the San Franisco point Nineers defense clamps down
the offense finds them consistently in the forty nine Ers
pick up an important win over the Jacksonville Jaguars. Why
because they got some tough games coming up, such as
Week five at LA take on the Rams on Thursday
(02:50):
night football. Crosstown rivalry heats up in the Rams out
the win, out the edge in a physical, bruising context,
giving the point nine Ers yet another loss on the season. Guys,
right now, the foty nine are sitting at two and
three on the year, with Wendel over the Saints and
the Jaguars nothing to write home about. They have a
(03:11):
huge mountain to start climbing to potentially get back into
this NFC West race, to potentially get to the playoffs,
matter of fact, just to potentially to have a winning season.
And Week number six, they're on the road take on
the Tampa Bay Buccaneers. This is not good in Tampa.
The sampsus for nine of struggle with al Kishra McCaffrey
probably at full strength. A one o'clock game across the
(03:34):
continental United States. Guys, the Tampa Bay Buccaneers take advantage.
Week of seven, they're back at home, take on the
Atlanta Falcons. This is a rare misstep at home against
an aggressive Atlanta Falcons team. Guys, questions start mounting. They
lost yet another game at home, giving them three losses
in a row, two of them which at home. But
(03:55):
then week number eight, everything starts to turn around just
a little bit. They travel to Houston take on the
Houston Texans. Guys, the San Franisco Finders get back on
track with a solid road win with a with against
a rebuilding Texans squad. They actually look dominant, potentially great
in this game, but it does not carry over to
week nine because they travel to New York to take
(04:15):
on the New York Football Giants to travel in inconsistent offense,
constant forty nine Ers in New York get again tough
loss on the road, another loss. They are starting to
mount up, and week number ten they are back at home.
The Niners reclaim bragging rights in the rivalry versus the
La Rams, delivering a statement win in front of a
home crowd. Defeating the La Rams in week ten, guys,
(04:37):
it does not look good for the Sanranisco four downers.
They are so inconsistent. They're so up and down. We
don't know what to do. Their defense has flashes, their
offense has flashes, but they very rarely put the two
flashes together at the same time. But then week number three,
sorry mid season, Week eleven through fourteen, they have a
little bit of a mid season surge. They finally get
on the right track. Everything starts to click, and it starts.
(05:00):
It starts to click a week eleven when they travel
to Arizona to take on the Cardinals, a big divisional
win on the road as the Niners hold serve and
they start to get the big momentum. Mid season serves.
Week twelve at home, take on the Carolina Panthers on Monday,
not football pause. Who's cuts with the Carolina Panthers at
samsisquain night, full foot football. That is stupid. I understand
(05:22):
CMC playings, the old team whatever, It's gonna be a blowout. Guys.
Primetime shines bright on San Francisco in a very convincing victory.
This game might be over at halftime. This is the
one game that I'm gonna be happy going to bed
at ten thirty at night, and now I have to
watch the whole second half. And then Week thirteen, it
continues when they travel to Cleveland to take on the Browns.
(05:42):
Travel doesn't slow them down this time, Oh no, no no.
The Niners put it to sell a team effort together
on the road debating the Cleveland Browns now. Week fourteen
is the bye week, a well deserved bye week of Britain.
It is time to get rested and regrouped because they
have just four games left of season. Right now, they're
fighting for everything. They're fighting for the finish. They need
(06:04):
to win for their four games out to potentially have
a shot at the playoffs, and week fifteen they do that.
Week fifteen they're back at home take on the Tennessee
Titans and Sancisco pounds out of physical win at home.
Cam Ward and the Titans do not know what hit them.
But then Week sixteen they travel to Indianapolis, Indiana to
take on the Colts on Monday Nights football. Another head
(06:26):
strategy Monday night football game. Why whatever? Right, but this
is another tough road game on Monday that ends in disappointment. Yes,
the Colts do be the Samsisu Quarre nineers come Week
six pretty much eliminating their playoff hopes. Week seventeen, they
are back at home take on the Chicago Bears. The
Niners close out on a double widget win with a
strong home showing, and then Week eighteen playing the Seahawks
(06:48):
and then winning that one as well. The season finale
against the Seahawks, the Niners take control and end on
a high note. So, guys, right now, I have the
Semsistic quare nwinners, and not as a very good team.
I have them as about a ten win team. That's
about it. Yes, I was high on them. I still
think the ceiling still remains that fourteen wins, and it
(07:10):
is very it is as a matter of fact, it
is absolutely possible if everything clicks and the team stays healthy. However,
their floor is eight wins. If Brandon Ayuk does not
come back eight hundred percent, if Christian McCaffrey does not
last the holes the whole season, if George Kittle is
banged up just a little bit, seven eight wins, guys,
(07:31):
is very very realistic, guys. This season for the SAMESISO
four nineers is all about finding consistency amids the chaos. Right.
If the four nineers get hot, the sky's the limit.
If not, they'll fails to rebuilding test. But what do
you guys think? Fourteen wins? Is it still realistic if
you're SAA, Sisco Cool four nine or sand or is
it more likely going to be eight wins? Guys? Coming
(07:51):
down below, this is a live interact to show subscribe,
hit the like button. Remember live money through Thursday at
nine pm East Coast time, right here on Man Hour.
So let's get into the commics, guys. That is gush
your thoughts. Old Man River Pig skin Pun get yourself
says that the San Fransisco forty nine ers will be
nine and eight. That is tough. That is tough, baby.
(08:14):
But I'm pretty close right there with you. I'm pretty
close right there. I have them right at ten wins,
potentially nine right nine, ten wins. Sadie says the Niner
will be nine and eight as well. I think a
lot of us are going on the same page we are.
We are kind of down on the San Francisco forty
nine ers. Now, let me ask you guys, this old
man River, Alpha Rob, Jim Sadie, the people that are
in the chat right now, are we down on the
(08:38):
Niners because of the trade of Debo, the injury of
Brandon Brandon ayyuk or do we not trust brock Purty.
Those are all the questions that I have for the
San Francisco forty nine ers. Alpha Rob says, they't finish
ten and seven. They had their chance for the last
couple of seasons and it's now it's time to rebuild.
You are correct. The forty nine or Super Bowl window
(08:59):
was wide o brock Purty under the rookie contract. They
had Deebo, they had Brandon Ayuthy, had George Kittle, a
fresh CMC everything was clicking. That Devons was top notch.
Now they don't have Drake green Law. Now they don't
have Fred Warner. Nick Bosa is another year older. Eric
Armstead's gone. You know, honestly, the Foyt nine ers are
(09:20):
rebuilding without rebuilding. Let's just be flat honest. They are
rebuilding without rebuilding. Hump baby girl. Bertie says, hey, Berti's
my puppy. Jim Pala says, the point Niners have to
play out of the quick stand just not enough horsepower.
And you know what, Jim, this is the first thing
that I think we've agreed on something in a long, long,
(09:41):
long long time. CMC has has every potential to be great,
but he's never played his full seventeen game season. CMC
could arguably be one of the best what if running
backs ever in the entire NFL history. Over Barry Standard,
over Bo Jackson, over Marcus Allen right, all those what
(10:02):
if running backs? Ap right, seems he could be the
biggest what if. Ever. Now they have the potential to
have a lot of horsepower. They have a V eight
engine that just need a little bit of fine tune
of They fine tune that just a little bit boom
to the moon baby. But right now they got a
misfire on cylinders four, five and six. What is going on?
(10:26):
But guys, what do you think? What will the San
Francisco for Nineters finished eight wins, nine wins, fourteen wins,
NFC West Championship, last place. What do you guys think?
What do you guys think? What do you guys think?
De Francisco forty nine ers guys at semransix four nineers
in their two thousand and twenty five season with a
lot of buzz. But after some offseason shake up, some injuries,
my outlooks have shifted quite a bit on the San
Francisco forty Hinders guys. Just three months ago, I had
the Niners of the fourteen win powerhouse team. I had
them running the NFC West. I had them going potentially
(00:20):
to the two Super Bowl. I had them dominating a
lot of these games. Arguably one of the best teams
in the NFL. But since then a lot of things
have changed. Deebo Samuel no longer a San Francisco forty
nine Ers. He is out traded to the Commanders. Christian McCaffrey.
Injuries are starting to pack up yet again. Brandon Ayuk
(00:42):
probably won't even be back till October or November at
this particular time. Right, the wide receiver room fields like
a game of musical chairs. Every time you turn it
is the signing of a ride receiver here firing this guy,
releasing this guy, like it is just a circle of
we don't know what to do with our hands. In
San Francisco, as of right now. It is tough, right,
(01:04):
it is very, very tough. But with all these factor
guys tempered the optimism, temper the optimism guys. But so
let's break down the Sanisco for its twenty twenty five
schedule game by a game with the win lost prediction.
I think weeks one through five, guys, they start out rocky.
I think it is a rocky if you are San
Francisco for four to forty nine fan. Because week one,
(01:25):
they travel to Seattle to take on the Seahawks, and
they start to see them off at a loss on
the road, a loud environment, a hostile Seattle crowd, new
quarterback nice, rookie receiver Devas is coming back, leading to
doom two point zero. The Niagos struggle to find rhythm
and they drop with the home opener That is tough, sorry,
the road opener. Week number two, they're back on the
(01:48):
road yet again, taking on the New Orleans Saints. This
ton of team bounces back with a solid road win
over the Saints, guys showing flashes of their old dominance.
Now let's not get crazy, because in in the end,
it is New Orleans Saints. In the end, New Orleans
States are going to be one of the worst teams
in the NFL. In the end, the Orleans Saints Kobe
gonna have the number one overall pick. Drafting arch maning.
(02:08):
Let's just call it spades be at the end of
the day. But Week three, finally the home opener, the
Arizona Cardinals coming to San Francisco could candle light Levi
Stadium whatever you want to call it. A tough divisional
battle ends and heartbreak at home. The Cardinals are just
a sneaky good team this season. Guys, do not sleep
on the Cardinals, but give them another loss. But then
(02:29):
finally back at home yet again, take on the Jacksonville Jaguars.
This time, the San Franisco point Nineers defense clamps down
the offense finds them consistently in the forty nine Ers
pick up an important win over the Jacksonville Jaguars. Why
because they got some tough games coming up, such as
Week five at LA take on the Rams on Thursday
(02:50):
night football. Crosstown rivalry heats up in the Rams out
the win, out the edge in a physical, bruising context,
giving the point nine Ers yet another loss on the season. Guys,
right now, the foty nine are sitting at two and
three on the year, with Wendel over the Saints and
the Jaguars nothing to write home about. They have a
(03:11):
huge mountain to start climbing to potentially get back into
this NFC West race, to potentially get to the playoffs,
matter of fact, just to potentially to have a winning season.
And Week number six, they're on the road take on
the Tampa Bay Buccaneers. This is not good in Tampa.
The sampsus for nine of struggle with al Kishra McCaffrey
probably at full strength. A one o'clock game across the
(03:34):
continental United States. Guys, the Tampa Bay Buccaneers take advantage.
Week of seven, they're back at home, take on the
Atlanta Falcons. This is a rare misstep at home against
an aggressive Atlanta Falcons team. Guys, questions start mounting. They
lost yet another game at home, giving them three losses
in a row, two of them which at home. But
(03:55):
then week number eight, everything starts to turn around just
a little bit. They travel to Houston take on the
Houston Texans. Guys, the San Franisco Finders get back on
track with a solid road win with a with against
a rebuilding Texans squad. They actually look dominant, potentially great
in this game, but it does not carry over to
week nine because they travel to New York to take
(04:15):
on the New York Football Giants to travel in inconsistent offense,
constant forty nine Ers in New York get again tough
loss on the road, another loss. They are starting to
mount up, and week number ten they are back at home.
The Niners reclaim bragging rights in the rivalry versus the
La Rams, delivering a statement win in front of a
home crowd. Defeating the La Rams in week ten, guys,
(04:37):
it does not look good for the Sanranisco four downers.
They are so inconsistent. They're so up and down. We
don't know what to do. Their defense has flashes, their
offense has flashes, but they very rarely put the two
flashes together at the same time. But then week number three,
sorry mid season, Week eleven through fourteen, they have a
little bit of a mid season surge. They finally get
on the right track. Everything starts to click, and it starts.
(05:00):
It starts to click a week eleven when they travel
to Arizona to take on the Cardinals, a big divisional
win on the road as the Niners hold serve and
they start to get the big momentum. Mid season serves.
Week twelve at home, take on the Carolina Panthers on Monday,
not football pause. Who's cuts with the Carolina Panthers at
samsisquain night, full foot football. That is stupid. I understand
(05:22):
CMC playings, the old team whatever, It's gonna be a blowout. Guys.
Primetime shines bright on San Francisco in a very convincing victory.
This game might be over at halftime. This is the
one game that I'm gonna be happy going to bed
at ten thirty at night, and now I have to
watch the whole second half. And then Week thirteen, it
continues when they travel to Cleveland to take on the Browns.
(05:42):
Travel doesn't slow them down this time, Oh no, no no.
The Niners put it to sell a team effort together
on the road debating the Cleveland Browns now. Week fourteen
is the bye week, a well deserved bye week of Britain.
It is time to get rested and regrouped because they
have just four games left of season. Right now, they're
fighting for everything. They're fighting for the finish. They need
(06:04):
to win for their four games out to potentially have
a shot at the playoffs, and week fifteen they do that.
Week fifteen they're back at home take on the Tennessee
Titans and Sancisco pounds out of physical win at home.
Cam Ward and the Titans do not know what hit them.
But then Week sixteen they travel to Indianapolis, Indiana to
take on the Colts on Monday Nights football. Another head
(06:26):
strategy Monday night football game. Why whatever? Right, but this
is another tough road game on Monday that ends in disappointment. Yes,
the Colts do be the Samsisu Quarre nineers come Week
six pretty much eliminating their playoff hopes. Week seventeen, they
are back at home take on the Chicago Bears. The
Niners close out on a double widget win with a
strong home showing, and then Week eighteen playing the Seahawks
(06:48):
and then winning that one as well. The season finale
against the Seahawks, the Niners take control and end on
a high note. So, guys, right now, I have the
Semsistic quare nwinners, and not as a very good team.
I have them as about a ten win team. That's
about it. Yes, I was high on them. I still
think the ceiling still remains that fourteen wins, and it
(07:10):
is very it is as a matter of fact, it
is absolutely possible if everything clicks and the team stays healthy. However,
their floor is eight wins. If Brandon Ayuk does not
come back eight hundred percent, if Christian McCaffrey does not
last the holes the whole season, if George Kittle is
banged up just a little bit, seven eight wins, guys,
(07:31):
is very very realistic, guys. This season for the SAMESISO
four nineers is all about finding consistency amids the chaos. Right.
If the four nineers get hot, the sky's the limit.
If not, they'll fails to rebuilding test. But what do
you guys think? Fourteen wins? Is it still realistic if
you're SAA, Sisco Cool four nine or sand or is
it more likely going to be eight wins? Guys? Coming
(07:51):
down below, this is a live interact to show subscribe,
hit the like button. Remember live money through Thursday at
nine pm East Coast time, right here on Man Hour.
So let's get into the commics, guys. That is gush
your thoughts. Old Man River Pig skin Pun get yourself
says that the San Fransisco forty nine ers will be
nine and eight. That is tough. That is tough, baby.
(08:14):
But I'm pretty close right there with you. I'm pretty
close right there. I have them right at ten wins,
potentially nine right nine, ten wins. Sadie says the Niner
will be nine and eight as well. I think a
lot of us are going on the same page we are.
We are kind of down on the San Francisco forty
nine ers. Now, let me ask you guys, this old
man River, Alpha Rob, Jim Sadie, the people that are
in the chat right now, are we down on the
(08:38):
Niners because of the trade of Debo, the injury of
Brandon Brandon ayyuk or do we not trust brock Purty.
Those are all the questions that I have for the
San Francisco forty nine ers. Alpha Rob says, they't finish
ten and seven. They had their chance for the last
couple of seasons and it's now it's time to rebuild.
You are correct. The forty nine or Super Bowl window
(08:59):
was wide o brock Purty under the rookie contract. They
had Deebo, they had Brandon Ayuthy, had George Kittle, a
fresh CMC everything was clicking. That Devons was top notch.
Now they don't have Drake green Law. Now they don't
have Fred Warner. Nick Bosa is another year older. Eric
Armstead's gone. You know, honestly, the Foyt nine ers are
(09:20):
rebuilding without rebuilding. Let's just be flat honest. They are
rebuilding without rebuilding. Hump baby girl. Bertie says, hey, Berti's
my puppy. Jim Pala says, the point Niners have to
play out of the quick stand just not enough horsepower.
And you know what, Jim, this is the first thing
that I think we've agreed on something in a long, long,
(09:41):
long long time. CMC has has every potential to be great,
but he's never played his full seventeen game season. CMC
could arguably be one of the best what if running
backs ever in the entire NFL history. Over Barry Standard,
over Bo Jackson, over Marcus Allen right, all those what
(10:02):
if running backs? Ap right, seems he could be the
biggest what if. Ever. Now they have the potential to
have a lot of horsepower. They have a V eight
engine that just need a little bit of fine tune
of They fine tune that just a little bit boom
to the moon baby. But right now they got a
misfire on cylinders four, five and six. What is going on?
(10:26):
But guys, what do you think? What will the San
Francisco for Nineters finished eight wins, nine wins, fourteen wins,
NFC West Championship, last place. What do you guys think?
What do you guys think? What do you guys think?
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