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July 19, 2025 4 mins
Welcome back to Ozempic Weightloss Unlocked, where we illuminate the latest about Ozempic’s role in weight loss, health, and lifestyle transformation.

Ozempic is in the spotlight as more people turn to it for help with weight loss, whether or not they have diabetes. GoodRx reports that Ozempic works by mimicking a hormone in your body that helps regulate blood sugar and suppress appetite, leading to fewer calories consumed. It also slows down how quickly food leaves your stomach and reduces sugar production in the liver. These combined effects can result in gradual, sustained weight loss.

Clinical trials published by GoodRx show that people on a 1 milligram weekly dose of Ozempic lost an average of 13 pounds over about nine months. Even at the lower, 0.5 milligram dose, people with Type 2 diabetes lost about 8 pounds over seven months. While some use Ozempic for Type 2 diabetes, doctors may prescribe it off-label for weight loss in people with prediabetes to lower their risk of developing diabetes.

However, Ozempic is not for everyone. Wegovy, which contains the same active ingredient as Ozempic, is actually approved by the Food and Drug Administration for weight loss in adults and children over 12 who are obese or overweight with at least one weight-related condition, such as high blood pressure.

One of the biggest questions is why some people have better weight loss results than others using Ozempic. Medical News Today highlights new research showing that several factors influence outcomes. Longer time on the medication, higher starting body fat, and even blood sugar levels all appear to play a role in weight loss success, especially for men. For women, lower skeletal muscle mass was linked to greater weight loss. Results can be variable, and doctors caution that more long-term studies are needed to determine how best to maintain the benefits after stopping the medication.

Not all effects of Ozempic are positive, and side effects are an important consideration. According to GoodRx, many people experience nausea, vomiting, and stomach pain, especially when first starting Ozempic or increasing their dose. Typically, these symptoms get better over time, but careful oversight and gradual dose increases help minimize discomfort.

Another critical issue is how Ozempic affects body composition. Healthline reports on a new study showing that weight lost with Ozempic is not just fat—muscle mass can decrease as well. This is especially a concern for older adults and women. To help prevent muscle loss, researchers recommend upping your protein intake and engaging in regular strength training while on the medication. Registered dietitians suggest aiming for at least one point two to one point five grams of protein per kilogram of body weight each day, but always consult your healthcare team before making big diet changes.

Another recent headline comes from Medical Xpress, which reports early indications that Ozempic could have benefits beyond weight loss, such as reducing the risk of stroke and complications related to certain brain injuries. These findings are still developing, but add to the growing discussion about the wide-ranging impacts of these new medications.

While many achieve meaningful and sometimes life-changing results on Ozempic, experts stress the importance of close medical supervision. There is concern about people receiving these medications from providers outside of their usual healthcare teams, which can result in less comprehensive follow-up and care.

To all our listeners: if you are considering Ozempic for weight loss, talk openly with your healthcare provider. Personal factors like muscle mass, body composition, existing conditions, and your ability to stick with healthy eating and exercise habits all influence your results and reduce risks.

Thank you for tuning in to Ozempic Weightloss Unlocked. If you found today’s insights helpful, be sure to subscribe so you never miss an update. This has been a quiet please production, for more check out quiet please dot ai.

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Transcript

Episode Transcript

Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:00):
Welcome back to Ozepic weight Loss Unlocked, where we illuminate
the latest about ozepic's role in weight loss, health, and
lifestyle transformation. Ozempic is in the spotlight as more people
turn to it for help with weight loss, whether or
not they have diabetes. GoodRx reports that ozepic works by
mimicking a hormone in your body that helps regulate blood
sugar and suppress appetite, leading to fewer calories consumed. It

(00:23):
also slows down how quickly food leaves your stomach and
reduces sugar production in the liver. These combined effects can
result in gradual, sustained weight loss. Clinical trials published by
GoodRx show that people on a one milligram's weekly dose
of ozepic lost an average of thirteen pounds over about
nine months. Even at the lower zero point five milligrams dose,

(00:44):
people would type two diabetes lost about eight pounds over
seven months. While some use ozepic for type two diabetes,
doctors may prescribe it off label for weight loss in
people with pre diabetes to lower their risk of developing diabetes. However,
ozepic is not for faye wegov, which contains the same
active ingredient, as ozempic is actually approved by the Food

(01:05):
and Drug Administration for weight loss in adults and children
over twelve who are obese or overweight with at least
one weight related condition such as high blood pressure. One
of the biggest questions is why some people have better
weight loss results than others using ozepic. Medical News Today
highlights new research showing that several factors influence outcomes. Longer

(01:26):
time on the medication, higher starting body fat, and even
blood sugar levels all appear to play a role in
weight loss success, especially for men. For women, lower skeletal
muscle mass was linked to greater weight loss. Results can
be variable, and doctors caution that more long term studies
are needed to determine how best to maintain the benefits

(01:47):
after stopping the medication. Not all effects of ozepic are positive,
and side effects are an important consideration. According to GoodRx,
many people experience nausey, vomiting, and stomach pain, especially when
first starting ozepic or increasing their dose. Typically, these symptoms
get better over time, but careful oversight and gradual dose

(02:09):
increases help minimize discomfort. Another critical issue is how ozenpic
effects body composition, health line reports on a new study
showing that weight loss with ozempic is not just fat,
Muscle mass can decrease as well. This is especially a
concern for older adults and women. To help prevent muscle loss,

(02:31):
researchers recommend upping your protein intake and engaging in regular
strength training while on the medication. Registered dietitians suggest aiming
for at least one point two to one point five
grams of protein per kilogram of body weight each day,
but always consult your health care team before making big
diet changes. Another recent headline comes from Medical Express, which

(02:55):
reports early indications that ozempic could have benefits beyond weight loss,
such as reducing the risk of stroke and complications related
to certain brain injuries. These findings are still developing, but
add to the growing discussion about the wide ranging impacts
of these new medications. While many achieve meaningful and sometimes

(03:15):
life changing results on ozempic, experts stress the importance of
close medical supervision. There is concern about people receiving these
medications from providers outside of their usual health care teams,
which can result in less comprehensive follow up and care.
To all our listeners, If you are considering ozepic for
weight loss. Talk openly with your health care provider. Personal

(03:38):
factors like muscle mass, body composition, existing conditions, and your
ability to stick with healthy eating and exercise habits all
influence your results and reduce risks. Thank you for tuning
in to Ozepic weight Loss Unlocked. If you found today's
insights helpful, be sure to subscribe so you never miss

(03:59):
an update. This has been a quiet please production. For
more check out quiet please dot ai
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