The Prime Minister claimed the next election will be a battle between Reform and the Labour Party, describing it as "the fight of our times" - and said it would be a "mistake" to ignore the threat Reform posed, dismissing claims he was fueling the fire by making Farage the focus of his attacks.
Peston also asks him - after the many bruising experiences of late - whether he ever thinks about packing it all in and handing the job over to someone else.
All episodes of Talking Politics are also available to watch on the ITV News YouTube channel and ITVX.
Got a question for the team? Email talkingpolitics@itv.com
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