The Real Python Podcast

The Real Python Podcast

A weekly Python podcast hosted by Christopher Bailey with interviews, coding tips, and conversation with guests from the Python community. The show covers a wide range of topics including Python programming best practices, career tips, and related software development topics. Join us every Friday morning to hear what's new in the world of Python programming and become a more effective Pythonista.

Episodes

Comparing Real-World Python Performance Against Big O

July 11, 2025 • 45 mins
How does the performance of an algorithm hold up when you put it into a realistic context? Where might Python code defy Big O notation expectations when using a profiler? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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Solving Problems and Saving Time in Chemistry With Python

July 4, 2025 • 73 mins
What motivates someone to learn how to code as a scientist? How do you harness the excitement of solving problems quickly and make the connection to the benefits of coding in your scientific work? This week on the show, we speak with Ben Lear and Christopher Johnson about their book "Coding For Chemists."
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Structuring Python Scripts & Exciting Non-LLM Software Trends

June 27, 2025 • 54 mins
What goes into crafting an effective Python script? How do you organize your code, manage dependencies with PEP 723, and handle command-line arguments for the best results? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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Scaling Python Web Applications With Kubernetes and Karpenter

June 20, 2025 • 64 mins
What goes into scaling a web application today? What are resources for learning and practicing DevOps skills? This week on the show, Calvin Hendryx-Parker is back to discuss the tools and infrastructure for autoscaling web applications with Kubernetes and Karpenter.
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Starting With marimo Notebooks & Python App Config Management

June 13, 2025 • 51 mins
Looking for a guide on getting started with marimo notebooks? How do you build a reproducible notebook for sharing or create a dashboard with interactive UI elements? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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Rodrigo Girão Serrão: Python Training, itertools, and Idioms

June 6, 2025 • 62 mins
Once you've learned the vocabulary and syntax of the Python language, how do you progress into learning the right combinations to put into your code? How can Python's built-in itertools library enhance your skills? This week on the show, we speak with Rodrigo Girão Serrão about teaching Python through his blog and his passion for the itertools library.
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Python Thread Safety & Managing Projects With uv

May 30, 2025 • 34 mins
What are the ways you can manage multithreaded code in Python? What synchronization techniques are available within Python's threading module? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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DjangoCon Europe 2025: Live Recording From Dublin

May 23, 2025 • 57 mins
What goes into making video courses at Real Python? How should you build an installable Django application? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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Going Beyond requirements.txt With pylock.toml and PEP 751

May 16, 2025 • 91 mins
What is the best way to record the Python dependencies for the reproducibility of your projects? What advantages will lock files provide for those projects? This week on the show, we welcome back Python Core Developer Brett Cannon to discuss his journey to bring PEP 751 and the pylock.toml file format to the community.
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Experiments With Gen AI, Knowledge Graphs, Workflows, and Python

May 9, 2025 • 59 mins
Are you looking for some projects where you can practice your Python skills? Would you like to experiment with building a generative AI app or an automated knowledge graph sentiment analysis tool? This week on the show, we speak with Raymond Camden about his journey into Python, his work in developer relations, and the Python projects featured on his blog.
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Exploring DuckDB & Comparing Python Expressions vs Statements

April 18, 2025 • 52 mins
Are you looking for a fast database that can handle large datasets in Python? What's the difference between a Python expression and a statement? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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Learning Intermediate Python With a Deep Dive Course

April 11, 2025 • 56 mins
Do you want to learn deeper concepts in Python? Would the accountability of scheduled group classes help you get past the basics? This week, five Real Python Intermediate Deep Dive workshop members discuss their experiences.
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GUIs & TUIs: Choosing a User Interface for Your Python Project

April 4, 2025 • 46 mins
What are the current Python graphical user interface libraries? Should you build everything in the terminal and create a text-based user interface instead? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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A Decade of Automating the Boring Stuff With Python

March 21, 2025 • 66 mins
What goes into updating one of the most popular books about working with Python? After a decade of changes in the Python landscape, what projects, libraries, and skills are relevant to an office worker? This week on the show, we speak with previous guest Al Sweigart about the third edition of "Automate the Boring Stuff With Python."
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Manage Projects With pyproject.toml & Explore Polars LazyFrames

March 14, 2025 • 48 mins
How can you simplify the management of your Python projects with one file? What are the advantages of using LazyFrames in Polars? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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Eric Matthes: Maybe Don't Start With Unit Tests

March 7, 2025 • 70 mins
Should you always start testing your code with unit tests? When does it make sense to look at integration or end-to-end testing as a first step instead? This week on the show, we speak with previous guest Eric Matthes about where to begin testing your code.
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Deciphering Python Jargon & Compiling Python 1.0

February 28, 2025 • 43 mins
How do you learn the terms commonly used when speaking about Python? How is the jargon similar to other programming languages? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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Telling Effective Stories With Your Python Visualizations

February 21, 2025 • 69 mins
How do you make compelling visualizations that best convey the story of your data? What methods can you employ within popular Python tools to improve your plots and graphs? This week on the show, Matt Harrison returns to discuss his new book "Effective Visualization: Exploiting Matplotlib & Pandas."
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Behavior-Driven vs Test-Driven Development & Using Regex in Python

February 14, 2025 • 57 mins
What is behavior-driven development, and how does it work alongside test-driven development? How do you communicate requirements between teams in an organization? Christopher Trudeau is back on the show this week, bringing another batch of PyCoder's Weekly articles and projects.
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Charlie Marsh: Accelerating Python Tooling With Ruff and uv

February 7, 2025 • 90 mins
Are you looking for fast tools to lint your code and manage your projects? How is the Rust programming language being used to speed up Python tools? This week on the show, we speak with Charlie Marsh about his company, Astral, and their tools, uv and Ruff.
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