MeSsy with Christina Applegate & Jamie Lynn Sigler
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
Episodes
August 26, 2025 • 62 mins
This week, Christina and Jamie read listener emails and discuss their kids starting the new school year, the power of manifestation, accepting reality, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com...
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August 19, 2025 • 59 mins
This week, Christina and Jamie read listener emails and discuss hormones, housewives, acknowledging the struggle, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Sleep Number - It’s the Sleep Number's Biggest Sale of the Year. 25% Off the i8 Bed plus free home delivery. Limited time. Exclusively at a Sleep Number® store...
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August 12, 2025 • 87 mins
This week, Christina and Jamie are joined by Ed Helms. They discuss working together on "Vacation," his love of comedy, the importance of curiosity, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Lola - Get 35% off your entire order at Lolablankets.com by using code Messy at checkout. Experience the world’s #1 blank...
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August 5, 2025 • 69 mins
This week, Christina joins Jamie live from the hospital in LA. They discuss what Christina’s going through, her recent trip abroad, their upcoming memoirs, the way the universe works, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
IRestore - Unlock your best hair & skin with @iRestorelaser and HUGE savings on the iR...
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July 29, 2025 • 71 mins
This week, Christina and Jamie are joined by Jenny Mollen, a New York Times bestselling author and actor. They discuss the feeling of not being in control, the trials of parenting, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Honeylove - Save 20% Off Honeylove by going to honeylove.com/messy #honeylovepod
Mudwtr - Start your...
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July 22, 2025 • 64 mins
This week, Christina and Jamie read listener emails and discuss wins and losses, shows that are easy on the nervous system, why people don't understand invisible diseases, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
O-Positiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at chec...
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July 15, 2025 • 72 mins
This week, Christina and Jamie are joined by Dr. Gretchen Hawley, an MS-certified specialist and physical therapist. They discuss what to do if you're feeling overwhelmed, the importance of staying consistent, why mindset is just as important as movement, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
Get the latest research from Doctor Gretchen here...
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July 8, 2025 • 60 mins
This week, Christina and Jamie read listener emails and discuss body work, Christina’s new obsession, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Star...
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July 1, 2025 • 88 mins
This week, Christina and Jamie are joined by Clea Shearer. They discuss how The Home Edit came to be, Clea’s breast cancer diagnosis, and the importance of fighting for your health and trusting your gut.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Function - Function currently has a waitlist, but they are offering my audience t...
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June 24, 2025 • 73 mins
This week, Christina and Jamie read listener emails and discuss how connected our bodies are with our emotions, friendship heartbreaks, starting a family, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Beam - Right now, Beam is offering UP TO 40% off their best-selling Dream Powder for our listeners. Perfect timing to lo...
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June 17, 2025 • 84 mins
This week, Christina and Jamie are joined by Judd Apatow. They discuss working on "Anchorman," parenting advice, spirituality, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today.
Magic ...
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June 10, 2025 • 61 mins
This week, Christina and Jamie read listener emails and discuss New York pizza, the trick to finding lost jewelry, how brain inflammation affects us, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an addi...
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June 3, 2025 • 62 mins
This week, Christina and Jamie are joined by Kaitlyn Bristowe. They discuss starting over, the impact of therapy, their love of dance, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
BetterHelp - This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on y...
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May 27, 2025 • 63 mins
This week, Christina and Jamie read listener emails and discuss being the “everything” friend, feeling validated in what you’re going through, finding support, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
Shop MeSsy merch: https://messypodcastmerch.giveswagger.com/messy_podcast_merch/shop/home
This episode is sponsored by:
BetterHelp - This epis...
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May 20, 2025 • 72 mins
This week, Christina and Jamie are joined by Christina’s TV brother, David Faustino. They share their memories from “Married... with Children,” and discuss the grief of losing a parent, choosing to live a sober life, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
Shop MeSsy Merch: https://messypodcastmerch.giveswagger.com/messy_podcast_merch/shop/h...
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May 13, 2025 • 86 mins
This week, Christina and Jamie are joined by Conan O'Brien. They discuss perspective, the importance of having morals, the circle of life, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
Shop MeSsy merch: https://messypodcastmerch.giveswagger.com/messy_podcast_merch/shop/home
This episode is sponsored by:
BetterHelp - “This episode is sponsored...
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May 6, 2025 • 66 mins
This week, Christina and Jamie read listener emails and discuss “Bad Moms,” princess cake, EMDR therapy, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
Shop MeSsy march: https://messypodcastmerch.giveswagger.com/messy_podcast_merch/shop/home
This episode is sponsored by:
BetterHelp - “This episode is sponsored by/brought to you by BetterHelp. Give...
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April 29, 2025 • 67 mins
This week, Christina and Jamie are joined by JoAnna Garcia Swisher, who is an actress, the co-founder of The Happy Place, and one of Jamie’s best friends. They discuss navigating grief, losing a parent, the power of authenticity, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
Shop MeSsy merch: https://messypodcastmerch.giveswagger.com/messy_podcast_merc...
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April 22, 2025 • 60 mins
This week, Christina and Jamie read listener emails and discuss the feeling of cleaning your closet, the difference between healing and fixing, doing the best you can, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
Shop MeSsy march: https://messypodcastmerch.giveswagger.com/messy_podcast_merch/shop/home
This episode is sponsored by:
MixTiles - Get 35% of...
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April 15, 2025 • 74 mins
This week, Christina and Jamie are joined by Diana-Maria Riva, who was Christina’s co-star on “Dead to Me.” They discuss their experience working together, how to sustain a career, finding your voice, her work with Latina’s Acting Up, and more.
Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Branch Basics - Get 15% off Branch Basics with...
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