This Week in Microbiology

This Week in Microbiology

This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

Episodes

April 26, 2025 46 mins

TWiM describes isolation of a novel bacterial species isolated from the China Space Station, and how a chemical radar allows bacteria to detect and kill predators.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin.

Guest Mark O. Martin.

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM explains how to recode E. coli so it uses only one stop codon, and an exploration of the mechanisms of bacterial adhesion within dental plaque.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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March 17, 2025 54 mins

TWiM explains Pasteur’s relentless hunt for microbes in the air, and how bacteria hunt for prey by ixotrophy - using grappling hooks!

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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February 28, 2025 46 mins

TWiM describes Shigella infection is facilitated by interaction of human enteric α-defensin 5 with a colonic epithelial receptor, and an amino acid change in RNA polymerase that leads to resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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...

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TWiM explains the remarkable abilities of bacterial ice nucleating proteins to promote freezing of water, and cryoprotective proteins produced by worm microbiomes that prevent freezing.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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January 24, 2025 53 mins

TWiM explores the discovery of microbial enzymes, PETases, that can degrade ubiquitous plastics, and how exogenous peptidoglycan is a danger signal to trigger biofilm formation.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson.

Guest Mark O. Martin.

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Music used on TWiM is composed and performed by Ronald J...

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January 10, 2025 41 mins

TWiM reveals that record high atmospheric methane growth has been driven by microbes, and the cecum as an adaptive niche for Salmonella typhi.

Hosts: Michael Schmidt, Petra Levin and Michele Swanson.

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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December 26, 2024 62 mins

From ASMCUE 2024, the conference on undergraduate education, TWiM speaks with Becky, Melanie, and Katriana about their careers and how they use TWiM in undergraduate microbiology education.

Hosts: Michael Schmidt and Mark O. Martin

Guests: Becky Seipel-Thiemann, Melanie Melendrez-Vallard, and Katriana Popichak

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December 13, 2024 59 mins

TWiM describes how to make concrete more ‘green’ by using microbes, and bacterial bioluminescence as an important regulator of multitrophic interactions in the soil.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and and Mark O. Martin.

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Music used on TWiM is composed and performed by Ronald Jenkees and used with...

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TWiM explains how ticagrelor alters the membrane of S. aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance, and the development of a novel continuous disinfectant technology that decreases healthcare-associated infections in ICUs by 70%.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson.

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November 8, 2024 60 mins

TWiM focuses on recent foodborne outbreaks of bacterial infections, and how nanopore sequencing technology can be used to identify pathogenic microbes and antimicrobial resistance genes in food products.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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October 25, 2024 75 mins

TWiM travels to the U.S. Army Medical Research Institute of Infectious Diseases to learn how research conducted at USAMRIID leads to vaccines, drugs, diagnostics, and training programs that protect both warfighters and civilians.

Hosts: Michael Schmidt, Petra Levin and Michele Swanson.

Guests: Norman Kreiselmeir, Christopher K Coat, Keersten Ricks, and Eric Nguyen

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October 11, 2024 52 mins

TWiM explains a project to engineer the cow microbiome to reduce emissions of methane, and the finding of antibiotic resistance genes in the genomes of giant viruses.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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September 27, 2024 67 mins

TWiM explains how bacterial community structure can be used to predict athletic performance in racehorses, and the idea that a tiny fraction of all species forms most of Nature.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Mark O. Martin.

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September 14, 2024 54 mins

TWiM explains unique modifications in the energy conservation pathways linked to methanogenesis in an Archaeon, and mechanisms of white nose fungal invasion of cells from the Little Brown Bat.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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TWiM describes experiments to explore gut microbiota signatures of vulnerability to food addiction in mice and humans, and how a phage tail-like protein suppresses competitors in populations of bacteria of plants.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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TWiM explores evolution and host adaptation of Pseudomonas infections of plants, and the impact of COVID-19 on ESBL-producing E. coli on urinary tract and blood infections.

Hosts: Vincent Racaniello and Michael Schmidt.

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TWiM explores the deep-dwelling microbes that sculpt our planet, and the use of microbes in bioelectronics to manage inflammation.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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From ASM Microbe in Atlanta, Georgia, Arturo joins TWiM to reveal the threats that fungi pose to human health, including the notorious Candida auris and many more and how committed experts are researching ways to save us and our food supplies.

Hosts: Michael Schmidt, Mark O. Martin

Guest: Arturo Casadevall

Watch this episode: https://youtu.be/nKJe5xN...

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TWiM explains a new mechanism for preventing lysogeny through temperate phage-antibiotic synergy, and Salmonella expansion in the murine gut dependency on aspartate derived from reactive oxygen species-mediated microbiota lysis.

Hosts: Michael Schmidt, Petra Levin and Michele Swanson.

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