All Episodes

September 30, 2025 31 mins

Chris and Xand continue their conversation with Dr James Rucker, a consultant psychiatrist at King's College London who is leading the European arm of a global trial of a psychedelic designed to treat people with severe depression.

They discuss the history of psychedelics, the discovery of LSD and the popular (and often illegal) practice of microdosing. Is there any evidence to suggest that taking minute quantities of psychedelic substances will boost your brain function or mood?

Chris and Xand also discuss their own experience of taking psychedelics several years ago for a TV series about traditional medicines.

If you’d like to share your thoughts on this or any other topic covered on the podcast, you email us at whatsupdocs@bbc.co.uk or Whatsapp on 08000 665 123.

Presenters: Drs Chris and Xand van Tulleken Guest: Professor Andy Smith Producer: Jo Rowntree Executive Producer: Rami Tzabar Editor: Kirsten Lass Assistant Producer: Maia Miller-Lewis Assistant Producer and Researcher: Emily Bird Tech Lead: Reuben Huxtable Social Media: Leon Gower Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

A Loftus Media production for BBC Radio 4.

Mark as Played

Advertise With Us

Popular Podcasts

Dateline NBC

Dateline NBC

Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

Are You A Charlotte?

Are You A Charlotte?

In 1997, actress Kristin Davis’ life was forever changed when she took on the role of Charlotte York in Sex and the City. As we watched Carrie, Samantha, Miranda and Charlotte navigate relationships in NYC, the show helped push once unacceptable conversation topics out of the shadows and altered the narrative around women and sex. We all saw ourselves in them as they searched for fulfillment in life, sex and friendships. Now, Kristin Davis wants to connect with you, the fans, and share untold stories and all the behind the scenes. Together, with Kristin and special guests, what will begin with Sex and the City will evolve into talks about themes that are still so relevant today. "Are you a Charlotte?" is much more than just rewatching this beloved show, it brings the past and the present together as we talk with heart, humor and of course some optimism.

Stuff You Should Know

Stuff You Should Know

If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.