APRIL PRIDE
The podcast for women changing their minds with the help of psychedelics is hosted by April Pride, a trusted voice at the intersection of psychedelics and women’s health. Whether you're curious about microdosing, integration, or harm reduction, April's podcast offers clinician-approved guidance, personal stories, and expert insights to help you intentionally navigate personal transformation with psychedelic medicine. aprilpride.substack.com
Episodes
Rosemary Woodruff Leary sat in a jail cell for a month rather than testify against her husband. While she was inside, Timothy Leary gave a ten page interview to Playboy about what LSD does to a woman's body and did not mention her once.
She was his editor, his translator, the person who read the room for him, and the organizer who coordinated his 1970 prison escape across the Weather Underground, the Black Panthers, and the Brotherh...
131. Can psilocybin help with menopause? A live audience of 300 at Town Hall Seattle asked Dr. Trish Singh and Kelly McGinty, C-FNP, co-authors of Mycelopause: Uncovering the Magic of Menopause with Psilocybin, the questions that don't come up in a doctor's office: whether psilocybin is safe after hormone-positive cancer, how it interacts with SSRIs, whether hormone therapy can start after 60, what's actually legal in Seattle in 20...
130. Psilocybin and Menopause: Two Clinicians Reframe Midlife for Women
Episode Summary
Estrogen regulates the serotonin system, and psilocybin reaches the same receptor. That is where this Salon starts, and it is the most specific version of the psilocybin and menopause conversation I have heard in public.
Kelly McGinty, a nurse practitioner, told a full room at Town Hall Seattle that the drop women feel in perimenopause is physiolog...
129. Psychedelics for Seniors: Aging & What's Next
Episode Summary
The psychedelic renaissance gets covered like a young person's story: executives microdosing before board meetings, twenty-somethings on retreats. But the fastest-growing population interested in this medicine right now is confronting retirement, widowhood, the death of parents, the question of legacy. This episode is a live Salon recording built around psychedeli...
128. Ancestral Trauma & Psychedelic Integration
A 45-year psychedelic guide on ancestral trauma, Internal Family Systems, and why integration, not the ceremony, is the real medicine.
Episode Summary
Most conversations about psychedelics stay at the level of the ceremony: the dose, the visions, the breakthrough. This episode goes somewhere else. Sand Symes has spent 45 years supporting women, first as a social worker, then as what ...
127. Psilocybin for Anorexia: Inside UCSF's Trial
Dr. Amanda Downey on UCSF's psilocybin trial for anorexia, why caregivers enroll, and what the medicine can and can't reach in eating disorders.
Episode Summary
Eating disorders are the deadliest psychiatric illness we have. Someone in the United States dies of one every 52 seconds, and two of every three people who get conventional treatment never fully recover. Anorexia nervosa has h...
126. Psychedelics & Addiction: What the Research Shows
Addiction psychiatrist Dr. Nathan Sackett on psilocybin, ibogaine, MDMA, ketamine, and what psychedelic-assisted therapy can and cannot do for substance use disorder.
Episode Summary
The conversation about psychedelics as addiction treatment is moving faster than the research. Dr. Nathan Sackett is trying to close that gap. Founding director of the Center for Novel Therapeutic...
125. The Wise Body: What Women's Hormones, Cycles, and Lived Experience Have to Teach Psychedelic Medicine
Stephanie Karzon Abrams of Galilea on why psychedelic care must account for women's cycles, life stage, and the knowledge that predates clinical trials.
Episode Summary
The research on psychedelics was built around male bodies. Women were treated as a confounding variable — their cycles, hormones, and life stages filtered o...
124. Psychedelic Integration and Intuition: What Actually Changes After Ayahuasca
Explore psychedelic integration and intuition through ayahuasca, grief, and leadership. What really changes after plant medicine?
Episode Summary
What actually happens after the ceremony ends? In this episode, April sits down with Lizzi Cutler to explore psychedelic integration and intuition beyond the peak experience. From ayahuasca to 5-MeO-DMT, Lizzi ...
123. Microdosing for Midlife: Emotional Resilience(Week 6)
Week 6 explores extinction learning, emotional resilience, and how microdosing may support gradual rewiring of fear-based patterns in midlife.
Episode Summary
This episode is part Week 6 of Microdosing for Midlife—a 12-part audio companion to the original Substack series.
In this conversation, April explores emotional resilience not as toughness or avoidance, but as the a...
122. Microdosing for Midlife: Stability & Nervous System Change (Week 5)
Week 5 explores masking, authenticity, the Default Mode Network, and how microdosing may soften rigid self-narratives in midlife.
Episode Summary
This episode is part Week 5 of Microdosing for Midlife—a 12-part audio companion to the original Substack series.
In this conversation, April explores authenticity not as a dramatic revelation, but as a gradual...
121. Microdosing for Midlife: Stability & Nervous System Change (Week 4)
Week 4 of Microdosing for Midlife explores how nervous system stability shapes identity, growth, and long-term change in midlife.
Episode Summary
This episode is part Week 4 of Microdosing for Midlife—a 12-part audio companion to the original Substack series.
In this conversation, April expands on what it actually means to feel stable while undergoing ch...
120. Microdosing for Midlife: Hormones, Perception, and Libido (Week 3)
Exploring how menopause, perception shifts, and nervous system regulation intersect with midlife libido.
Episode Summary
This episode continues Week 3 of Microdosing for Midlife, April Pride’s 12-part audio companion to her Substack series exploring microdosing through the lens of midlife transition.
In this conversation, April examines one of the most quietl...
119. Microdosing for Midlife: Brain Science of Change (Week 2)
Week 2 of Microdosing for Midlife explores estrogen, menopause, hormone therapy, and cognitive health—plus how psilocybin supports neuroplasticity.
Episode Summary
This episode marks Week 2 of Microdosing for Midlife, a 12-week audio series exploring how psilocybin microdosing for women intersects with hormonal change, emotional regulation, and cognitive resilience d...
118. Microdosing for Midlife: Intention Setting, Integration, and Finding Your Dose (Week 1)
Week 1 of Microdosing for Midlife explores intention setting, finding the right microdose, and integrating psilocybin gently during midlife transitions.
Episode Summary
This episode marks Week 1 of Microdosing for Midlife, a 12-week audio series exploring how psilocybin microdosing for women can support emotional awareness, intention, and inte...
117. Ibogaine Therapy Safety & Ethics: What Responsible Care Really Looks Like
A grounded conversation on ibogaine therapy safety and ethics—covering medical oversight, risks, integration, and responsible psychedelic care.
Episode Summary
Ibogaine is often described as a breakthrough for addiction, trauma, and PTSD—but it’s also one of the most medically complex psychedelic therapies in use today. In this episode...
116. Psychedelics and Aging: Meaning in Later Life
An educational conversation on psychedelics and aging, exploring meaning-making, grief, safety, and integration through lived experience and research.
Episode Summary
What happens when psychedelic experiences arrive later in life—after careers, caregiving, grief, and loss have already shaped the nervous system? In this episode, April Pride sits down with journalist and author Ab...
115. 5-MeO-DMT Experience Explained
A grounded conversation on the 5-MeO-DMT experience—how it affects the nervous system, how it differs from DMT, and why safety and integration matter.
Episode Summary
What is 5-MeO-DMT, and why do people describe it so differently from other psychedelics?
In this episode, April Pride sits down with licensed clinicians and facilitators Roger and Dustin to explore the 5-MeO-DMT experience through...
114. How to Start Microdosing with Psilocybin
A science-backed guide to microdosing psychedelics with SetSet’s 12-week protocol, featuring expert insight and lived experience.
Episode Summary
If you’ve been microdose-curious — or maybe you’re already experimenting and want a little more structure — this episode is your map. Host April Pride pulls together insights from SetSet collaborators including autho...
113. Psychedelic Law in Seattle: What’s Actually Legal in 2025?
SetSet Salon breaks down psychedelic law in Seattle with attorneys Perry Salzhauer & Daniel Shortt—what the entheogen resolution covers, what it doesn’t, and the risks it creates.
Episode Summary
Most people think Seattle has legalized psychedelics. It hasn’t—at all. In this episode, recorded live at SetSet’s Psychedelic Salon at To...
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