The Neurodivergent Entrepreneur

The Neurodivergent Entrepreneur

The Neurodivergent Entrepreneur is a podcast for ADHD, Autistic, and all other neurodivergent entrepreneurs who are building businesses, creative work, and lives that actually fit how their brains work. Hosted by Patrick Casale, LCMHC, this show is for people who want to create meaningful work, create outside of the box, grow their impact, and build something sustainable without losing themselves in the process. Being a neurodivergent entrepreneur can feel like holding a lot of contradictions at once. You may have big ideas, deep passion, creative energy, and a strong desire to do things differently. You may also be navigating burnout, masking, self-doubt, perfectionism, rejection sensitivity, executive dysfunction, inconsistent energy, and the pressure to keep showing up when your capacity is already stretched. This podcast speaks to that reality honestly, because building a business around your brain, your values, and your lived experience can be powerful, complicated, messy, and deeply personal. Patrick Casale is a chronically ill, AuDHD, mental health therapist, entrepreneur, TEDx speaker, event host, group practice owner, and neurodivergent business owner who has built, grown, burned out, pivoted, and kept going. His work brings together clinical insight, lived experience, business perspective, and real conversation about what it actually takes to create something that feels values aligned. His conversations are direct, compassionate, unfiltered, and practical, with room for both the emotional reality of entrepreneurship and the concrete decisions that shape a sustainable business. New episodes drop every Wednesday and feature honest conversations with neurodivergent entrepreneurs, creators, therapists, business owners, and leaders. Together, Patrick and his guests explore entrepreneurship, identity, mental health, chronic health, creativity, leadership, systems, money mindset, visibility, community, sustainable growth, and the behind-the-scenes reality of creating work that matters. Build your dream business. Protect your capacity. Work with your brain instead of against it.

Episodes

September 9, 2026 35 mins

What happens when neurodivergent burnout, chronic illness, stress, and medical trauma all start colliding?

Patrick Casale sits down with Dr. Zachary Spiritos for an in-depth conversation about complex chronic illness and why conditions like POTS, dysautonomia, ME/CFS, mast cell activation, hypermobility, and unexplained GI symptoms can be so difficult to navigate.

They explore the potential roles of stress, trauma, environmental expo...

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What if neurodivergent people aren't failing the systems around them—what if those systems are failing them?

Patrick Casale sits down with Autistic and ADHD (AuDHD) physician Dr. Mel Houser, founder of All Brains Belong, to explore why navigating healthcare, employment, chronic illness, and burnout can be so exhausting for neurodivergent people—and what it could look like to build something better.

From advocating for you...

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What happens when a TV show, book series, fictional universe, or character becomes so much more than entertainment?

Patrick Casale is joined by returning guest and ADHD Executive Function Coach Mandi Dixon for a deep dive into Game of Thrones, House of the Dragon, and the powerful role special interests can play in neurodivergent lives.

From favorite characters and dragons to Autistic-coded characters, PDA, hyperfixation, and the emo...

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What if the goal isn't to "fix" your ADHD—but to finally stop fighting yourself?

In this episode, Patrick Casale sits down with mental health advocate, content creator, and digital strategist Kyrus Keenan Westcott, whose honest, anti-toxic positivity approach has resonated with nearly 3 million followers. Together, they explore the realities of living with ADHD, executive dysfunction, burnout, perfectionism, and the lifelong p...

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Building a successful business isn't just about strategy—it's about finding people who truly understand how your brain works.

In this episode, Patrick Casale shares the deeply personal story behind the creation of the NeuroPreneur Circle and why he believes community is one of the most important ingredients for sustainable entrepreneurship. Drawing from his own experiences with autism, ADHD, chronic illness, masking, and searc...

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In this episode, Patrick Casale and Gabrielle Juliano-Villani pull back the curtain on what entrepreneurship really looks like when you're neurodivergent.

From burnout and chronic illness to purpose, friendship, travel, and creating businesses that actually fit your brain, this conversation explores the realities that rarely make it onto social media. They also share why they created the free Diverge Summit—a first-of-its-kind...

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In this episode, Patrick Casale talks with Becky Pierson Davidson, founder of Affinity Collective, about what it really takes to build meaningful, sustainable online communities—including for neurodivergent entrepreneurs.

Becky shares insights from her journey in product strategy, UX, and community design, plus the hard truths about memberships, monetization, and why passion-driven communities thrive.

3 key takeaways:

  1. Commun...
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Living and working with Hypermobile Ehlers-Danlos Syndrome (hEDS), along with comorbid conditions like Mast Cell Activation Syndrome (MCAS) and Postural Orthostatic Tachycardia Syndrome (POTS), means navigating a world that isn’t built for bendy bodies. In this episode, Patrick Casale reflects on his journey from college athlete to entrepreneur with mobility aids, and the realization of how much internalized ableism he's had ...

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In this episode, Patrick Casale talks with Alexandra (Alex) Wildeson, online content creator and host of the "Calling in Sick" podcast, about the realities of living with invisible and chronic health conditions, from gaslighting in the medical system to redefining success outside of capitalism's narrow achievement lens.

Here are 3 key takeaways:

  1. Community is Essential: Connecting with others who understand your experience is a ga...
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In this episode, Patrick Casale talks with Dr. Emma Offord, a UK-based clinical psychologist and founder of Divergent Life, about the landscape of autism and ADHD assessment, both in the U.K. and U.S., and the urgent need to move past deficit-based models to truly affirming, accessible care.

3 Key Takeaways:

  1. Systemic barriers to diagnosis are everywhere: Whether it’s a years-long wait for a free assessment in the U.K. or ga...
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Navigating business ownership as a neurodivergent entrepreneur can be both challenging and empowering, offering independence and autonomy in work life while also requiring constant self-assessment of needs and capacity. In this episode, Patrick Casale talks with Natalia Rivera, a trauma-informed therapist specializing in high-masking Autistic adults, about how late-in-life neurodivergence discovery impacts entrepreneurship and the ...

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I've been sitting with this for a while, and honestly? It's been unfolding naturally, in real time, for longer than I've cared to admit.

If you've been listening to All Things Private Practice over the past year or two, you may have noticed something shifting. The conversations were changing. I wasn't just talking to therapists about starting group practices or building caseloads anymore — I was sitting across from neurodiverg...

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In this episode, Patrick Casale talks with Katherine L’Etang (A.K.A. @TheNeurodiversityMom) about her journey as a late-diagnosed Autistic and ADHD adult, which is both powerful and relatable, especially for advocates, parents, and neurodiverse professionals.

Here are 3 key takeaways:

  1. Self-advocacy is essential: It's important to seek validating, knowledgeable professionals—and not settle for invalidating experiences,...
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In this episode, Patrick Casale talks with Yael Clark and Liam Spicer about building neurodiversity-affirming mental health spaces and the Neurodiversity Affirming Therapy Conference Australia & LOAPAC Expo.

They discuss how collaboration among neurodivergent professionals can drive change—whether by centering lived experience, innovating inclusive practices, or redefining what “professional” environments look ...

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In this episode, Patrick Casale talks with Jodie Hill, who is the founder & managing partner of Thrive Law, a neurodivergent solicitor, and a passionate advocate for mental health, equity, and neuroinclusion in the workplace. Her lived experience and legal expertise shed light on the daily realities—challenges and opportunities—for neurodivergent professionals and their employers.

Here are 3 key takeaways:

  1. Psychol...
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In this episode, Patrick Casale shares a brutally honest look at living with chronic neuroimmune conditions while trying to keep up with plans, business, and even just daily life. If you’ve ever felt like your body is working against you and struggled to keep up with the demands of life, you’re not alone.

Patrick opens up about the exhausting intersection of autism, ADHD, POTS, MCAS, Ehlers-Danlos, chronic pain, burnout,...

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In this episode, Patrick Casale talks with Mandi Dixon, LPC, EMDR therapist, and ADHD executive functioning coach, about the intersection of ADHD and perimenopause, an area with far too little research and awareness—despite how profoundly it impacts so many lives. Mandi shares both expertise and lived experience, highlighting the real challenges faced by neurodivergent individuals navigating this transition.

3 Key Takeaways:

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In this episode, Patrick Casale talks with Michelle Moseley, LCMHC, who provides trauma-informed, weight-inclusive, and neurodivergent-affirming counseling for survivors of religious/spiritual harm and individuals who struggle with body image.

They discuss the factors that play into religious and spiritual harm, including the impact it can have on a person, and what therapeutic approaches are helpful vs. harmful.

Here are 3 key takea...

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In this episode, Patrick Casale talks with Pasha Marlowe, a mental health expert, neuroinclusion speaker, consultant, and coach, about her neuroinclusion work on improving workplace culture and leadership, which stemmed from seeing the real harm that some non-inclusive systems can inflict on neurodivergent employees. Neuroinclusion isn’t just about supporting and attracting Autistic or ADHD team members—it’s about...

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In this episode, Patrick Casale talks with Liz Ridgway about her career journey—how growing up as an athlete in small-town Pennsylvania ultimately led her to founding MENTL.SESH, collaborating with brands like Nike and NASCAR, and supporting high performers and creatives through therapy and consulting.

After years in nonprofit and foster care settings, Liz realized the importance of bringing all passions and parts of herself i...

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