Tiny Matters

Tiny Matters

Science shapes every part of our lives, but so much of its influence is overlooked or buried in the past. Tiny Matters is an award-winning podcast about tiny things — from molecules to microbes — that have a big and often surprising impact on society. From deadly diseases to forensic toxicology to the search for extraterrestrial life, hosts and former scientists Sam Jones and Deboki Chakravarti embrace the awe and messiness of science and its place in history and today, and how it could impact our world’s future. New episodes every Wednesday. Tiny Matters is brought to you by the American Chemical Society, a non-profit scientific organization based in Washington, D.C., and is produced by Multitude.

Episodes

October 15, 2025 27 mins

For thousands of years, the rise and fall of empires and the global economy were closely tied to something you might not expect: spices. The spice trade began around 1000 BCE, localized to southeast Asia and the Middle East. But by the beginning of the next millennia, it had rapidly expanded and nations vied to control it. Today it’s typically far less work to find and purchase spices you want, but just because they’re no ...

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In this episode of Tiny Show and Tell Us, we get to the bottom of if glass is a liquid or a solid and why riboflavin makes milk fluorescent. Then we talk about the Laser Interferometer Space Antenna (LISA) — the first space-based observatory that NASA scientists and their collaborators are sending up into space to detect and study gravitational waves, better known as “ripples in spacetime.” 

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In 1856, after yet another day of disappointing experiments, a chemist named William Henry Perkin was cleaning up his glassware when he made a discovery that would harken a new — and colorful — era of science and industry. Just 18 years old, Perkin was a promising young student in a prestigious lab at the Royal College of Chemistry in London and he was supposed to be figuring out a way to make a chemical compound called qu...

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In this episode of Tiny Show and Tell Us, a listener on “team wasp” writes in with some interesting info on USDA wasps for pesticide-free pest control and we learn about some wasp versus beetle drama. Then we talk about how our red blood cells use and expel iron, and how a huge percentage of the iron we get is from broken down blood cells.

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Back in April, a company called Colossal Biosciences announced that they had brought dire wolves — ancient canines of Game of Thrones fame — back from extinction. The internet went wild. But while some media outlets proclaimed the return of a long-gone species, many scientists shot back on social media that these weren’t really dire wolves, they were just genetically engineered grey wolves. Suddenly everybody had an opinio...

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In this episode of Tiny Show and Tell Us, we talk about cute woolly mammoth mice and debate whether research to bring back extinct species (or their genes) is ethical or a good use of money and time. Then we discuss the best way to remove microplastics from water.

We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact o...

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How did the early Earth, over four billion years ago, evolve into the planet we know and love today? It’s a big question, and an open question. To get answers, geologists turn to a surprising source — a tiny mineral no bigger than the diameter of a human hair, that has secrets about our planet locked away in its crystal structure. This miniscule mineral, with its big stories is called zircon.

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In this episode of Tiny Show and Tell Us, we talk about a new and exciting biodegradable polymer that seems to outperform commercial super glues. Then we discuss a compound called sulfur hexafluoride (SF6) that is used in high voltage equipment. Not only is SF6 a potent greenhouse gas, if you breathe it in it has the opposite effect of helium — it makes your voice deep. But it can also lead to asphyxiation so you should no...

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August 20, 2025 33 mins

An estimated 132 million babies were born across the globe last year — really just a drop in the bucket when you think about the over 100 billion babies born since modern humans first lived on Earth 200,000 years ago. And until very recently we had few tools to understand how they were doing in the womb, how they would fare in the days after birth, and how a pregnant person would change physically and mentally not just dur...

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In this episode of Tiny Show and Tell Us, we talk about breathing in birds — how it takes two breath cycles for air to leave their bodies, and while it travels within their bodies, it's stored in various sacks, some of which are in their butts. Then we discuss how food waste contributes to approximately 8% of global greenhouse gas emissions every year, and what we can do to reduce it. 

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3,500 years ago, cats started showing up in Egyptian paintings on tomb walls and in sculptures and carvings. Not only were they abundant in these representations, but it was very clear that they were domestic. They had collars around their necks and were eating out of food dishes underneath the dining room table. That scene is not so different from the life many cats lead today. So how did cats go from the wild to being im...

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In this episode of Tiny Show and Tell Us, we tackle the debate surrounding whether or not it rains diamonds on Saturn. Then we talk about how UV degradation can break down some of the harmful residual dyes from plastic pollution, and what it means in the context of microplastics.

We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorit...

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On May 7, 1981, influential physicist Richard Feynman gave a keynote speech at Caltech. Feynman opened his talk by politely rejecting the very notion of a keynote speech, instead saying that he had his own ideas on what to discuss and that everyone should speak on what they please. And for Feynman, this meant proposing a new technology that could simulate physics with computers. That lecture 44 years ago is widely consider...

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In this episode of Tiny Show and Tell Us, we cover squirrel pox — a disease that hasn’t had a huge impact in the United States but has decimated populations of squirrels in the UK. Then we talk about the story that Napoleon's army lost the Battle of Waterloo because the military uniforms used tin buttons that broke apart in cold temperatures, making it harder for the troops to survive. But is there any truth to that story?...

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In January, 1997, David Nierenberg was a physician at Dartmouth‐Hitchcock Medical Center, specializing in toxicology. Chemist Karen Wetterhahn was placed in his care. When she arrived at the hospital, Karen was slurring her speech and having difficulty balancing and with coordination. What David soon learned was that her symptoms were all due to a few tiny drops of a compound called dimethylmercury. Today’s episode focuses...

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In this episode of Tiny Show and Tell Us, we talk about how climate change may impact the effectiveness of mental health medications and how heat waves impact mental health more generally. Then we cover how fetal heart rates can change depending on which language they’re hearing while in the womb.

We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form*...

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Climate change has brought forth extreme fire events, like the Palisade and Eaton fires in Los Angeles, which devastated communities in Altadena and the Pacific Palisades in the beginning of 2025. And it’s becoming harder to not wonder: Is this just the world we live in now? Under the constant threat of catastrophic fires? Fortunately, we have the perfect guests to answer that question. We traveled to NASA’s Goddard Space ...

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In this episode of Tiny Show and Tell Us, we talk about why the FDA recently banned Red Dye No. 3 and how concerned people should be about its use in food. Then we cover icy winter roads and the fascinating science behind clearing them and taking a more sustainable approach that won’t hurt the environment.

We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out th...

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In 1975, NASA launched two spacecraft to Mars. Viking 1 and Viking 2 arrived at their destination less than a year later, each bringing a lander to explore the surface of the planet and an orbiter to survey above. What was supposed to be a 90 day mission ended up lasting until the early 1980s. Those years provided scientists with important data about the Martian landscape, from seismometer readings of marsquakes to the red...

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In this episode of Tiny Show and Tell Us, we talk about what dark energy and dark matter are made out of and how knowing more could upend our understanding of the Big Bang. Then we cover microchimeric cells — cells transferred between baby and mom — and how new research in mice shows that fetal cells that took residency in mom from a first pregnancy are replaced by new fetal cells of a second pregnancy.

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