Johns Hopkins Mosquito Minute

Johns Hopkins Mosquito Minute

Impactful malaria science and the trailblazers leading the fight. A podcast from the Johns Hopkins Malaria Research Institute in partnership with the Naked Scientists.

Episodes

October 5, 2026 • 19 mins

For decades, scientists pursued one goal: a vaccine that could prevent the disease. But malaria is caused by a complex parasite, making vaccine development far more challenging than for most infectious diseases. One scientist dedicated his career to this challenge. Sir Adrian Hill of the University of Oxford witnessed children dying from malaria in Gambia in the late 1980s and set out to develop a vaccine that could save lives wher...

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Chris talks with Dr. Justin Boddey from Melbourne's WEHI about a promising new way to halt malaria, and make people immune at the same time.

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Host Chris Smith speaks with Andrea Manica, an evolutionary ecologist at the University of Cambridge, about what our ancient ancestors can teach us about grappling with malaria.

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Chris speaks with Sonia Shah, author of The Fever, about the history of malaria and human efforts to control it. 

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Why the continent accounts for the overwhelming majority of cases.
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World Malaria Day 2026 is marked under the theme Driven to End Malaria: Now We Can. Now We Must.

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Professor Jane Carlton is director of the Johns Hopkins Malaria Research Institute. Dr. Chris Smith of the Naked Scientists interviews Jane about her research, her career and the future of malaria. 

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In sub-Saharan Africa, mothers often carry their babies on their backs in colorful cotton wraps called lesu. Could treating these wraps with insecticide help prevent malaria? Dr. Ross Boyce discusses a groundbreaking study in Uganda showing that permethrin-treated wraps significantly reduce malaria in infants – and further, what this could mean for protecting the youngest and most vulnerable children from this of...

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A new study in rural western Uganda finds that treating baby-carrying cloths, or lesu, with an insecticide with modest repellent effect significantly reduces malaria infections in young children.

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In many parts of sub-Saharan Africa, mothers carry their young children on their backs in colorful cotton wraps called lesu. Could treating these cloths with insecticide reduce malaria tran...

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Too much can kill the mosquito — too little can also kill it. But the right amount can strengthen the mosquito's defenses and stop malaria transmission. Today, the Goldilocks dose. Emma Camacho shares how a natural compound called L-DOPA strengthens mosquitoes' defenses at just the right concentration, revealing a new way to block malaria transmission.

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Feeding mosquitoes L-DOPA can either strengthen their defences against malaria or shorten their lifespan — showing that in vector control, the dose makes the difference

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As with all medicine, the dose determines whether something helps or harms.

Researchers recently looked at a substance commonly found i...

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How do you turn vast amounts of genetic data into actionable insight – efficiently and accurately? Professor Bryan Greenhouse of UCSF discusses a series of "hackathons" at the Johns Hopkins Malaria Research Institute (JHMRI) that bring together scientists from around the world to tackle one of the biggest challenges in malaria research: analyzing parasite genetics. By developing open-source tools, workflows, and ...

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Although severe malaria presents in different clinical forms – such as cerebral malaria or severe malarial anemia – a new study reveals that all severe cases have one thing in common: a shared inflammatory signature

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Whilst most cases of malaria are mild, some take a dangerous turn. In severe cases, the malaria parasite can overwhelm the body, disrupting the blood-brain b...

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Dr. Alexandra Probst discusses a breakthrough in malaria prevention: bed nets coated with anti-parasitic drugs that stop transmission by curing infected mosquitoes.

With Alexandra Probst, former graduate student at Harvard University.

About The Podcast

The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malaria research and to share it with the global comm...

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How next-generation bed nets could stop malaria by killing the parasites inside mosquitoes, not just the mosquitoes themselves.

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Bed nets have long been a cornerstone of vector control. Coated with insecticide, they serve a dual purpose: preventing bites and killing mosquitoes. But what if those nets could do more – not only kill the mosquitoes, but for those they don't kill be...

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The extent to which malaria vaccines reduce cases and deaths is a key consideration. But there's another factor, too.

with Dr. Lemu Golassa, Head of Medical Parasitology at Addis Ababa University.

About The Podcast

The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malaria research and to share it with the global community.

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A recent study in Ethiopia reveals that local malaria parasite strains differ genetically from those targeted by current vaccines, potentially reducing their effectiveness.

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The recent introduction of two malaria vaccines in sub-Saharan Africa represents a major success in global health, and the culmination of decades of research and development. The two jabs – RTS,S and R21 &n...

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