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October 8, 2025 31 mins
In this Ageless Future episode, Cade Archibald focuses on optimizing blood flow, endothelial health, and insulin sensitivity to prevent the twin threats of heart disease and type 2 diabetes. He explains why improving nitric oxide and mitochondrial function is foundational, then maps out practical levers—whole-food nutrition, HIIT intervals, post-meal walks, sauna/cold plunge hormesis, sleep, and even oral microbiome care. Cade spotlights advanced testing (ApoB/ApoA ratios, fasting insulin and HOMA-IR, CIMT ultrasound) and discusses tools ranging from GLP-1 agonists and tesofensine to tissue-repair peptides (BPC-157, TB-4) and umbilical-cord–derived regenerative therapies. Listeners get a weekly “stack” (low-dose GLP-1, BPC-157, beet nitrates, berberine) plus simple training cues (grip-strength tracking, sprints/intervals) to boost nitric oxide, repair vessels, and build a heart-healthy, longevity-driven routine. 

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