CXOTalk

CXOTalk

C-Suite Conversations on AI & Strategy. Join industry analyst Michael Krigsman for unfiltered discussions with the leaders shaping the future of business. From AI implementation to digital transformation, hear directly from CIOs, CTOs, CEOs, and more from the world's largest companies. No scripts. No PR fluff. Just real questions from our live audience and honest answers from the C-Suite. Want to participate? Get invited to the next live show: https://www.cxotalk.com/subscribe

Episodes

January 6, 2026 โ€ข 22 mins

Nation-states are already harvesting your encrypted data, betting they'll crack it when quantum computers mature. It's happening now.

In CXOTalk episode 904, Anand Oswal, Executive Vice President of Network Security at Palo Alto Networks, explains what business leaders need to understand about quantum security and how to address it. The impact of quantum computing on cybersecurity will be huge.Key timelines discussed:-- Cry...

Mark as Played

Most enterprises aren't ready for agentic AI, but ChristianKleinerman, Snowflake's EVP of Product, shares practical advice on what it takes to succeed: data readiness, governance, AI economics, and workforcestrategy.


In this episode of CXOTalk, Kleinerman draws on 25 years ofenterprise technology experience to give leaders a realistic roadmap for AI adoption. He explains how to evaluate AI vendors in hours instead of mon...

Mark as Played

Can a digital replica of your heart save your life? In CXOTalk episode 902, Michael Krigsman talks with Dr. Joe Alexander, Director of the Medical and Health Informatics Lab at NTT Research, to explore the revolutionary world of Bio-Digital Twins.Discover how researchers are using mathematical modeling to build "computational replicas" of the human cardiovascular system. Dr. Alexander explains how these digital twins can ...

Mark as Played

How do you turn a 150-year-old industrial giant into an agile, AI-first organization?

=======

Please support our sponsor Emeritus:

Explore executive education programs from Emeritus, in collaboration with top universities: https://cxotalk.partner.emeritus.org/

=======

For Hexion CEO Michael Lefenfeld, the answer isn't just about technology, but about culture, safety, and rethinking value. In episode 901 of CXOTalk, Lefenfeld details his...

Mark as Played

๐Ÿšจ STOP treating AI like just another automation tool; you're missing the real transformation.

 

Most executives are approaching AI completely wrong. They're focused on automating tasks when they should be reimagining their entire business model. In this landmark 900th episode of CXOTalk, Sangeet Paul Choudary, advisor to 40+ Fortune 500 CEOs, reveals why AI is actually COORDINATION INFRASTRUCTURE, not just a productivity tool.

&...

Mark as Played

Microsoft invested $13 billion in OpenAI. Amazon poured billions into Anthropic. The AI oligopoly is here. Lord Tim Clement-Jones and Lord Chris Holmes, architects of UK AI policy, reveal what business leaders must know about Big Tech's grip on AI - from vendor lock-in risks to circular funding patterns signaling bubble collapse.

 

๐Ÿ”ท Show notes and resources: https://www.cxotalk.com/episode/house-of-lords-members-on-ai-does-big...

Mark as Played

Is your organization stuck in AI pilot purgatory? CIO strategic advisor Tim Crawford reveals how enterprise AI is fundamentally transforming the CIO role, and why the decisions you make today will determine which IT leaders succeed tomorrow.

 

=======

Please support our sponsor Emeritus:

Explore executive education programs from Emeritus, in collaboration with top universities: https://cxotalk.partner.emeritus.org/

=======

 

In ...

Mark as Played

Please support our sponsor Emeritus:

Explore executive education programs from Emeritus, in collaboration with top universities:

https://cxotalk.partner.emeritus.org/

=======

Will Grannis, Chief Technology Officer of Google Cloud, explains Google's vision for agentic AI and multimodel LLMs, including these key topics on CXOTalk #897:

-- The latest AI news from Google

-- Why "AI as judge" determines whether your agent deploy...

Mark as Played

Is your AI built on quicksand? Learn how bad data, poisoned datasets, and deep fakes threaten your AI systems, and what to do about it.

In this episode of CXOTalk (#896), AI luminaries Dr. David Bray and Dr. Anthony Scriffignano reveal the hidden dangers lurking in your AI foundations. They share practical strategies for building trustworthy AI systems and escaping the "AI quicksand" that traps countless organizations.

๐ŸŽฏ K...

Mark as Played

AI luminary and former Group CEO of Technology at Accenture, author Paul Daugherty, offers a hard-hitting take on enterprise AI and consumer-grade artificial intelligence on CXOTalk episode 895.


He examines what's working, where companies stall with their AI transformation, and what new technology trends leaders should monitor.


Peer into the future of AI and see the importance of responsible AI development.


๐Ÿ”ท Show no...

Mark as Played
September 26, 2025 โ€ข 55 mins

How did Salesforce build a $200B company by declaring war on "software"? Branding expert Laura Ries (author of "Strategic Enemy") reveals why the world's best brands choose strategic enemies to dominate their markets.

Laura explains the counterintuitive positioning strategy behind iconic brands like Tesla, Chick-fil-A, and White Claw. Learn why opposition creates clarity, how visual hammers make brands unforg...

Mark as Played

In cybersecurity, identity has become the primary attack vector. We explore identity in CXOTalk 892, with the CEO of RSA Security, Rohit Ghai, who explains how stolen credentials, social engineering, and AI-enabled impersonation break defenses. And what boards, CISOs, and executives must do now.

What youโ€™ll learn:

-- Why credential theft remains the #1 initial access vector and what โ€œphishing resistantโ€ MFA actually requires

-- How at...

Mark as Played

Learn how a unified Zoho platform and centralized data analytics reduced app sprawl, speed decisions, and improved customer experience for Zoho customer Nuvia Dental. The discussion provides a practical playbook for leaders seeking fewer apps, stronger data integrity, and clear ROI.


ย ๐Ÿ”ท Show notes and resources: https://www.cxotalk.com/episode/data-first-operations-a-zoho-playbook-for-measurable-outcomes

๐Ÿ”ท Newsletter: www.cxotalk.co...

Mark as Played

Too often, AI breaks in the wild. Why? CXOTalk 890 dissects the adversarial economy with Steven C. Daffron (fintech private equity leader) and Anthony Scriffignano (distinguished data scientist), hosted by Michael Krigsman.

ย 

Discover the challenges of **ai implementation** and the strategies needed to navigate the **future of work** in an AI-driven world. Stay informed with expert insights on CXOTalk.

ย 

What youโ€™ll learn:

  • How AI en...
Mark as Played

Is AI coming for your job? Boston Consulting Group's Global Lead for People and Organization, David Martin, reveals the truth about workforce disruption, survival strategies, reskilling, and the future of work.

With only 20% of employees effectively using AI tools despite 80% expressing excitement, discover why adoption is failing and what leaders must do differently.

๐ŸŽฏ Key Insights You'll Gain:

-- Why software developers and white-c...

Mark as Played

When AI systems hallucinate, run amok, or fail catastrophically, the consequences for enterprises can be devastating. In this must-watch CXOTalk episode, discover how to anticipate and prevent AI failures before they escalate into crises.

Join host Michael Krigsman as he explores critical AI risk management strategies with two leading experts:
• Lord Tim Clement-Jones - Member of the House of Lords, Co-Chair of UK Parliament's A...

Mark as Played

Art Hu, Global CIO at Lenovo, shares proven strategies for implementing AI at scale in one of the world's largest technology companies. Learn how to navigate uncertainty, build organizational agility, and drive real business value from AI investments.

In this episode, you'll learn:

  • Why "no regret" AI investments beat waiting for perfect solutions โ€ข How to transform fear of job loss into workforce empowerment โ€ข T...
Mark as Played

Zendesk CEO Tom Eggemeyer joins Michael Krigsman to discuss the impact of AI CX on customer expectations. They explore real-world lessons from the Zendesk AI journey, including what has worked and what hasn't. Learn how customer service is being reshaped by ChatGPT and artificial intelligence and machine learning.

Key Topics Covered:

  • The shift from traditional chatbots to reasoning AI agents
  • Why Zendesk only gets paid when AI ...
Mark as Played

What does it take to keep global financial markets stable during extreme volatility and AI-driven trading? Chris Isaacson, Chief Operating Officer of Cboe Global Markets, the world's largest options market exchange, reveals the high-stakes playbook for building resilient systems, people, and processes that handle over a trillion messages a day without failure.

In CXOTalk episode 885, we go behind the scenes of one of the world&#...

Mark as Played

The generative AI revolution has created an insatiable demand for efficient, powerful computing. How is a key industry leader like AMD navigating this critical inflection point?

In CXOTalk episode 884, Michael Krigsman sits down with Mark Papermaster, CTO and Executive Vice President of AMD, to explore the future of AI infrastructure.

Discover AMD's strategy for winning in the AI era, which hinges on a tight integration of hardw...

Mark as Played

Popular Podcasts

    If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

    Crime Junkie

    Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you wonโ€™t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, youโ€™ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by Audiochuck Media Company.

    NFL Daily with Gregg Rosenthal

    Gregg Rosenthal and a rotating crew of elite NFL Media co-hosts, including Patrick Claybon, Colleen Wolfe, Steve Wyche, Nick Shook and Jourdan Rodrigue of The Athletic get you caught up daily on all the NFL news and analysis you need to be smarter and funnier than your friends.

    Dateline NBC

    Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

    The Breakfast Club

    The World's Most Dangerous Morning Show, The Breakfast Club, With DJ Envy, Jess Hilarious, And Charlamagne Tha God!

Advertise With Us
Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

ยฉ 2026 iHeartMedia, Inc.