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October 15, 2025 33 mins

How does food DNA impact the human body? In what ways do ecological communities in the gut change and adapt to individual people over time? Join us in this episode as Dr. Sean Gibbons discusses a breakthrough method that analyzes food-derived DNA in fecal metagenomes – and what this means for human health…

Dr. Gibbon leads the Gibbons Lab at the Institute for Systems Biology, where he works to better understand and improve how the gut microbiome affects our health, utilizing a range of approaches, from hands-on experimentation to computer tools. His goal is to help create more personalized medical treatments. How? By accurately tracking dietary intake from gut microbiome samples and ultimately fostering better nutrition research and overall precision health.

Click play to find out:

  • How the human microbiome influences our responses to diet, drugs, and more.
  • What food DNA is, and where this idea comes from.
  • The strongest driver of microbiome composition.
  • How accurate dietary data is collected.

Dr. Sean Gibbons earned his Ph.D. in Biophysical Sciences from the University of Chicago in 2015. He then completed postdoctoral training in Eric Alm’s lab in the Department of Biological Engineering at MIT (2015–2018), where he developed techniques to measure how the human gut microbiome changes and evolves in individual people. He is now a full-time microbiome researcher and an Associate Professor at the Institute for Systems Biology.

Want to follow along with Dr. Gibbons’s work with Gibbons Lab? Click here now!

Episode also available on Apple Podcasts: http://apple.co/30PvU9C

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