Generation Bold, December 20, Young Goose

More to come

Episode Transcript

(00:08):
When I look in the mirror,I don't see wrinkles. When I look
in the mirror, I see hairon my head, not my shoulder.
And hello, Hello, Hello,This is Adrian Berg and this is Generation
Bowl, the fountain of truth,the fountain of truth about what well,

(00:30):
the fountain of truth about aging.And today we're going a little bit off
course, but probably it's going tobe to show that most of you listen
to A want to listen to becauseit is about being more beautiful. Yes,
I'm gould have put it just thatway. It's about all the things
that would make you look better forreally good scientific reasons, not because you

(00:51):
have just gone through thousands of dollarsworth of surgery, you got pricked in
the face, or who knows whatelse. The fact is that if we
feel better on the outside, wefeel better on the inside too. I
do believe that. By the way, vanity is a great motivator for healthy
aging. And I'm not one ofthose people who go gray, don't worry

(01:14):
about wrinkles. It is important tome. I'm saying, Aladdin, proud
to look my best. And ifI have a biological age that's younger than
my chronological age, why should Ilook even older than my chronological age.
So it's a rare occasion for us. I'm very happy to welcome Amity a
shell. Now, he's a biohacker. He's going to tell you what that

(01:34):
means. But more important for us, he's the CEO of a company that
manufacturers and researchers and develops topicals.You might want to call that cream.
My mother, she would have calledit cold cream. She would say,
oh, Amity, you make coalcream. Well, the fact is that
he's the CEO of Young Goose anda fascinating product among the tons of products

(02:00):
out there. And I'll introduce itby telling you that one of the reasons
is it puts on my face.A lot of the things that I take
internally in my nutraceuticals, and youprobably have heard of some of them,
is very troll and nad. Sothank you for being with us today.
It's absolutely my pleasure. I'm veryexcited to be a guest, and you

(02:23):
know I love our interactions face toface, so I'm very excited for this
conversation. Well, I'll tell youthat even more exciting is the way we're
going to start, and that's reallybecause of you. I think that my
listeners know that the skin is thebiggest organ of the body. It is
the largest organ of the body ifyou look at size. And one of

(02:45):
the things that Amity said was he'sgoing to be speaking soon at a conference
to biohackers, meaning people who reallydo want to interfere with your own aging
and make life longer and healthier.About skin, not what it does as
you age, because you age,but the other way, how the condition
of your skin can age you.So let's hear about that, Amity.

(03:08):
Well, that's obviously a long hourlecture. But to make the things very
very simple, our skin is basicallya barrier to the environment. That's what
you know. Gives us protection tothe when we are exposed to the elements
and distressors, and as we growolder, because of that first line of

(03:30):
defense, it just accumulates a lotof a lot of damage. And that
damage gets translated into cells that aredysfunctional, into DNA damage and a few
other things that don't only make uslook older, but actually drive aging throughout
our whole body through a few differentpathways, but through creating inflammation. A

(03:54):
lot of people don't know that asan organism, our skin is controlling some
of the hormones that we create.UM, and that axis, that skin
brain axis. The older the skinbecomes, the older the brain becomes because

(04:14):
of that axis, and obviously theolder brain becomes, then it titrates to
the entire body. So basically,as more youthful we can keep the skin,
um, we will contribute to wholebody aging as a whole. And
of course, UM, there aremany, many, many studies correlating the

(04:35):
perceived age someone is, so howthey how old they look, and they
are their biological age. So wecould look at it from from many different
angles. So let's make the connectionthough, between beauty care and healthcare,
which is just what you're doing whenyou deal with a topical like young Goose.

(04:59):
Would it be the same a kindof topical that would keep your skin
healthy so that it maintains its immunebarrier versus the kind of beauty care that
would simply make you, as yousay, look better. Is it the
same substances that you're researching or thesetwo different protocols for two different purposes.
That's that's a great question. AndI think within that longevity or the within

(05:21):
the health span field or health optimizationfield, we should be aiming at three
things we should be aiming at.You know, molecules that make us perform
at our highest output at the moment, contribute to short term health and contribute

(05:41):
to longevity long term health. Andwhen you have that ven diagram when these
three things, when we have amolecule that does these three things, that
is a molecule that we want todeal with. For example, in ID
is one of them, or asveratrol, or we can talk about synalytics.
But molecules that do all these thingsalso make you look good right now,
also makes your skin healthy for theshort run, but also obviously contribute

(06:08):
to longevity. And we can talkabout when that does not happen when there's
only two out of three. Butthe molecules that we deal with are also
important short term and also long termas far as the skin is concerned.
So I'm actually holding in my handnow and we'll see if we can get
a picture of it on our website. Remember, Adrianberg dot com will also

(06:30):
be archiving this show as well asgoing on iTunes and iHeartRadio and all over.
So I'm holding now one of yourpremiere products. It's called Young Goose
YG care and it has three thingson it. It has resveratrol, which
is something that we talked about alot on this show. It's why people

(06:51):
like to have red wine because it'sit comes from that sort of of a
molecule. You've also got an arenoble, and you've also got matrixal matrixle.
I think those are the three thingsthat you feel can be part of
a topical. That also are thingsthat we've often taken a pill or a

(07:14):
nutraceutical. Yeah, and I'll tellyou more than that. That actually has
about ten to twelve things that you'dbe probably taking in a nutraceutical or in
oral form, and we've translated themto something that can absorb to your skin
and help your skin as far asboth you know, looking better and functioning

(07:35):
in a more youthful state. SoCOQ ten, PQQ, even tumeric and
vitamin C are all in that formulation, alongside things that are less known but
are going to be more known astime goes on, such as an estragulous
extract. If anyone knows the oralsupplements TA sixty five, that's very similar

(07:56):
to what we're using there for telomera. Think. So, yeah, that
product is kind of our kitchen sink. It's a moisturizer that has in our
nobile is probably what we're proud ofthe most. This is a an NAD
precursor that can raise an AD levellevels in the skins. So it's not

(08:16):
going to do it in the restof your body, but it's going to
do it in your skin. Andwe obviously match it with a patented version
of resveratrol that is also skin specific. And the reason that we want to
do that is because our skin doesn'tfunction like our gut. It doesn't know

(08:39):
how to usher in molecules like ourgut. It speaks a different language,
so to speak. And the moleculesfirst of all, have to be different
size. They have to we haveto make sure that the skin knows what
to do with them. And ifyou remember, like um, I don't
know, ten twenty years ago,all the fancy creams used to have collagen
in them. Yes, and it'sanyone who's listening to us now, I'm

(09:03):
sure he is educated to the extentthat they know that collagen doesn't really absorb
through the skin, even though theskin needs it. So we need to
basically find a way to take thosemolecules that you know are giving you a
health benefit when you ingest them andhave them translated in a way where they
would benefit your skin. And whywould we want to do it in the

(09:24):
skin specifically, because your skin,for the most part, is the last
organ that is going to enjoy itwhen you take it as in a pill
form or even as an iv ordepository. Your body, as we grow
older, prioritizes its internal internal organs, muscles, brain, even bones,

(09:50):
rather than the skin. And weobviously can see that right as we grow
older, the skin ages faster thanyour liver ages, for example. So
when we taken any deep supplement,for example, the amount that's going to
get to the skin under your eyesor you know, between your eyebrows is
very little, nonexistent really, sowe have to supply the skin with those

(10:15):
molecules directly. Haven't said that.Yeah, when we come back, I
do want to continue this, andI do want to have everybody realized that
there's several layers of skin. I'mgoing to put you on the spot to
talk about how these molecules that you'vecreated in young bose get through the skin
all and is just a topical andbefore we sign off, just this spot.

(10:37):
How do we find you? Guys? We want to learn more,
so you could go to our website, which is Young Goose dot com,
Young Like the Age, Goose Likethe Bird dot com and where we do
supply. A lot of information ison our Instagram and Facebook pages. You
can find it through Young Goose Skincare. If you look up Young Goose Skincare,

(11:00):
whether it's a Facebook or Instagram,you'll find us. And when we
come back, we're gon be talkingmuch more about sagging and wrinkles and all
the things that we've bombarded with allthe time from a beauty point of view,
and again their relationship to our health. Don't you go anywhere all man.
But that doesn't bother me, noteven because I am happy and I'm

(11:24):
inappropriate for my aid. You maythink that I'm all love. That doesn't
bother me, not even because Iam happy and I'm inappropriate. Oh my,

(11:48):
and hello, hello, Hello,this is Adrian Bergen. This is
Generation Bold. The generation that talksabout pickle ball is not my generation.
My gen ration is the one thathas no time for pick a ball.
Wishes they had time for pickaball,but they're too busy changing the world and
eventually they'll get to pick a ball. Yeah, I know there's a new

(12:11):
book called pick a Ball for Dummies. I think it's a apt title for
a book, and I am tryingto get the author on and we'll have
a little bit of a debate.So I've nothing. You know, I
love exercise, I love pickaball,but I also love the information that could
change your attitude toward aging. Andthat's what we do here. And today
we're doing this in a wonderful way, a very unique way for us.

(12:33):
We're speaking with Amity Eschelle. Nowhe is the CEO of Young Goose.
Young Goose is beauty products. I'mgonna call it. He probably calls him
something much more sophisticated. I callhim beauty products. But he has such
a different approach. Now, rememberwe don't take any money. We do
not sell this, we don't havean affiliate program. I'm still using it

(12:54):
to see how it goes for me, because you have to use something that's
topical for a while to see howit goes. But I'm so fascinated with
the health angle that this company usesthat I really had to bring it to
you very early. So you wereexplaining to us in a nutshell, that

(13:15):
if we are keeping our skin,the largest organ in our body, healthy,
not only are we doing that tolook better, but it affects our
organs, It affects our immune system, our hormone system. And you were
explaining to me during the break thatthere's a difference between intrinsic and extrinsic aging
when it comes to the skin andwhat it means to us. So let's

(13:39):
delve into those definitions. Okay,So intrinsic aging basically means that processes within
the body our body. Aging affectsour skin. Extrinsic aging means aging is
that is that the skin goes throughthat is associated with exposure to the element

(14:00):
and the stressors in the environment.And what most people don't know is that
eighty percent of the way our skinages is from that exposure to stressors.
It's not from how well we treatour body as a whole. And that
is important to understand because if wewant to look good, Unfortunately, as
time goes on, it's not onlyit's not enough just to take care of

(14:24):
the inside and kind of neglect ourskin. We need to do both.
And if we really want the skinto look we really need to put a
lot of emphasis as far as whatwe put on our skin and make sure
it's effective. And because of that, so what happens when we are getting
exposed to the element we get alot of damage is as far as DNA

(14:46):
damage. So obviously a lot ofpeople are familiar with the damaging effects of
UV radiation from the sun, butyeah, but many people don't know that
high and high energy visible light,so artificial light pollution and EMF electromagnetic fields,

(15:07):
they are all part of that.Those stressors that age our skin.
And as time goes on, thatDNA damage accumulates and it requires more and
more resources that the body starts tolack, so the body doesn't have the
resources to treat all of that damage. And what happens is that snowball.

(15:28):
More damage accumulates, more resources needthe skin needs the less it has,
more damage accumulates, so on andso forth, and what it drives is
cells that are called sinescent cells orzombie cells. And these cells they don't

(15:48):
die. That's basically a mechanism thatour body developed to avoid cancer. So
when the body doesn't recycle cells verywell, it basically puts them in jail
and in growth arrest, they can'tthey can't multiply anymore. But they're they're

(16:08):
stuck between kind of living and dying. So they're not dying, but they're
creating. Instead of creating good beneficialmolecules and communication to other cells, they're
only creating inflammation and they can infect. So it's called SASP. That's type
of inflammation and that can infect othercells in that malady in being senescent.

(16:34):
So again there's a snowball effect andguests where what tissue has the most amount
of senescent cells as we grow older? Hint, the tissue that gets exposed
to the element, right, wouldthat would be epidermist itself, the actual
top layer of skin. So theepidermist normal mostly is dead. It's just

(16:55):
like tiles on a house. That'swhy you could slough it off, that's
why you explode. And they saythat every twenty eight days you'll get the
new cell growth there. So that'svery typical. Yes, but this the
epidermist has a vital role as faras our skin health and youthful state because
it prevents nutrients and height and moisturefrom escaping the skin, and it also

(17:18):
provides the antioxidant defense for the skin. But that's kind of the end of
it. It's kind of the shieldour dermist and hypodermist. These are the
layers that are alive in air quotes, you know, so to speak,
in the skin. And what happensis that when they start to develop that
senescent activity, so them themselves,these dermist cell dermal cells specifically, they

(17:45):
can become senescent. But also thepigment cells, for example, they're called
melanocytes, the ones that create thepigment melanin. They are very susceptible to
sinescence because they're being activated from UVradiation, from blue light that we have
from screens and artificial light, andfrom other irritants. They become senescent.

(18:07):
They affect immune cells that we havein our skin to become senescent, and
even the layers of the protective layersof our blood cells that usher blood into
our skin can become senescent as well. And what happens that all of the
orchestra of inflammation, of low gradebut constant inflammation, it starts to seep

(18:32):
into our body and exacerbate a processcalled inflammaging, which is where inflammation drives
aging. They don't only do itthrough that cascade where one cell kind of
touches the other and affects it.But unfortunately, as I mentioned before,
our skin has a roll of basicallybeing like at the forefront as far as

(18:55):
exposure to the element and relaying theinformation back to our brain in that system.
What we're gonna do a many iswe're seeing here this incredible connection because
inflammating is a word that we doknow. It's one of the elements of
why we age and one of thereasons that we take things that are anti
inflammatories and nutraceuticals, and we're concernedabout it. And for the first time

(19:18):
here many of us are hearing thisconnection. Now when we come back,
we're going to ask the obvious question, what can we do about it?
Don't you guys? Go anywhere?But that doesn't bother me, not even
because I am happy and I'm inappropriatefor my age. You may think that

(19:45):
I'm all bother me, not evenbecause I am happy and I'm inappropriate.
Oh my hello, hello, Hello, This is Adrian Bergen. This is
Generation Bold, Generation Bold, theFountain of Truth about aging. And I

(20:08):
recently went to two conferences back toback conferences. One was called Radfest and
that was an interesting live conference inSan Diego, and I did a few
videos for you covering that conference.All you have to do is reach me
by going to Adrianberg dot com slashcontact that you'll see all the contact information,

(20:30):
all the things you can get ifyou contact us, but simply leave
me a message there. Very easy. I would like to understand what's going
on with Radfest. Radfest is aconference that started out really on the fringes
of science talking about immortality and isgetting closer and closer to what the geroscientists
are also finding. So there's thisconvergence between the extreme longevitists and the FDA

(20:53):
and geroscience. Right now, thetwain has not met. But if you
go to both conferences, the secondand one called the Catalist Institute for the
Delay and Prevention of Age Related Diseasesthat took place online, who will be
live next year in Washington, DC, you're seeing a real convergence between thinkers
about longevity and immortality and geroscientists,which means that we're at a tipping point

(21:18):
of making a difference for all ofus as we age. Now. One
of the things that we've been concentratingon for a long time individually many of
us is how good we look.Let's face it, if you look it
on the outside, you feel betteron the inside. But we have been
approaching it from a beauty point ofview, a cosmetic point of view.
There is a company and I havethe CEO of that company with me right

(21:41):
now. His name is Amity Ischell. He is the co founder and the
CEO of Young Goose, taking acompletely different angle on the beauty aspects of
health. And if you've been listening, you know that he's made a connection,
a geroscience connection between body inflam inflammation, our immune system, and how

(22:03):
good we actually look. But hissolutions, Amity, are topicals, products
that you can put on your faceor what my mom would have called cold
cream. And the fact is thatthey have many of the nutraceuticals that we
that we take in, like resveratroland nad And I've had so many shows

(22:26):
on all of these things. Uh, And so let's let's talk about that
with all of your deep knowledge,Emity, with regard to how we age,
You've you've channeled that to what areproducts that help us with wrinkles,
vibrancy and so on? In adifferent way. Can they be mixed?
Can you go into and get ayou know, an ola and use it

(22:48):
with your products? Is it necessary? What's the practical way that a consumer
should use your products? Well,that's a great question. So our products
are are not cheap, so they'rethey're pretty they're pretty expensive, so it
would be it would actually be veryimportant for me to relay the fact that

(23:10):
we have now around fifteen products andif someone finds a product that speaks to
them, they can definitely just integrateit to their existing routine where where they're
comfortable with what they're using and justadding another product. Obviously, we can
also provide an entire curriculum, anentire system to be that someone uses only

(23:33):
our products and really applies on theirskin and into their skin the same ingredients
that I'm sure that you're you're speakingabout every in every show that relates to
what we put in our body.And again, what we do as a
company is we are making sure thatthe same discoveries that people are talking about

(23:53):
as far as whole body aging andthe molecules that drive and aging in a
whole body perspective, we do itspecifically for the skin because as we spoke
about until now, our skin isnot getting first priority when we when we

(24:14):
ingest something, or when we injectsomething, or or even suppositories. Our
skin is kind of the late thelast thing that our body cares about as
we grow older. And unfortunately,again like we said before, what happens
is that, especially in our fifth, sixth, seventh, eighth, um
decades into our lives, that's thatstarts to kind of shift where our skin

(24:40):
affects the aging, the whole bodyaging. Now, one of the things
that we do, some of usknow we do oxygen facials. Be honest
with you, I've had oxygen facials. It's never meant much to me.
I've had some other good facials thathave been more important. But you do
have a hyperbaric mask oxygen therapy.Now, in other of the young goose,

(25:03):
you do have things the names weknow, like you said, in
a D plus resveratrol, many othersyou mentioned fifteen or sixteen different even vitamin
see and so on. But thisis different. This is oxygen Now.
Why this because this is your maskand I'm interested to know why you have
selected that and what you what theeffects are that you've seen correct, and

(25:27):
you're right, We actually don't haveoxygen in the mask because the problem is
not and you'll see it across acrossthe board. Every product we make,
the idea is to have the skinbehave in a more youthful state. And
actually, if you want to knowthe kind of our goal is every product
makes the skin behave about twenty yearsyounger in functionality. And so the way

(25:55):
that the mask does it is notnecessarily supplime or oxygen to the skin,
because the skin, to your point, doesn't really know what to do without
more oxygen, but it increases theability of the skin to use oxygen.
The problem is not having the skinhave more oxygen, is the skin being
able to use it and create energyout of it. And as we grow

(26:15):
older, the skin that every organin our body, but especially our skin
cells, they are capped to theamount of energy that they can create from
oxygen, or the cost of energycreation rises and because of that rising cost,
the skin cannot activate different anti agingpathways, some of them you might

(26:37):
have heard the names of, likecertuins or NERF two and r F two,
or you know collagen genes for example, that's something that sure everyone's heard
of. So what the mask doesit first of all, amps up the
amount of ATP, the amount ofcellular energy that our cells can make in
our skin, and then activates thosepathways that I mentioned, and our two

(27:02):
seer two wins collagen production through anepigenetic perspective through gene expression. Now,
that's something I do want to bringout just in general, because we do
talk about this a lot. Whenyou look at the hallmarks of aging,
the first thing that a consumer andaverage guy is going to say is genetics.
My parents had crappy genetics or theyhad great genetics, or whatever it

(27:25):
is, and that's how I'm goingto age. And more and more we're
learning that that's not the case.Your actual genetics is a very small percentage
compared to your epigenetics, which ishow your genes are expressed, and they
have a lot to do with yourstress, your food of people. Now
in the FDA, actually we hadDan Bellski, great genoscientists, how you

(27:47):
were brought up, what your educationwas, whether you were abused or coddled.
So many things trump your genes.And are you saying that that's true
with the beauty of your skin,that if your mom and Dan had great
skin, maybe you not and theother way around. Yeah, definitely,
if they did have great skin,it eighty percent of it, as we

(28:08):
said before, would be because ofthe environment they were exposed to and their
habits that made them be exposed toan environment, and also obviously what they
applied on their skin. So ifyou have good skin and your parents did,
eighty percent of it is because ofthe lifestyle they brought you into and

(28:29):
not the genetics that they kind ofyou know, brought into the conversation.
And I'm gonna say more than that. You could think of your genetics as
a recipe for whatever, as arecipe for for a dish, but as
we know, one recipe could beyou know, used extremely differently and create

(28:51):
different results for different people. Thereare better cooks and worst cooks, and
that's a good way in my opinion, to look at epigenetics. So what
are we doing with those genes?And we do know that studies of let's
say, identical twins with the samegenetics, they live very differently, very
long, shorter, with health withouthealth because of the lifestyle they live.

(29:12):
So I'm going to end this episode, this little session for we take a
break with something for my mom Mymom had beautiful skin, and I always
assumed that genetically I would get ittoo, and to some extent I do.
But why I asked her at ageninety one if she had any life

(29:33):
lessons, because, after all,it was her ninetieth birthday, and I
figured she was going to give somereal wisdom at her ninetieth birthday party,
and you're gonna love this. Shesays, yeah, I'll think about this,
and then she said, don't forgetto moisturize, and that was her
life lesson after ninety years. Yeah, there you go. You could use

(29:56):
that on you as a brand.Don't forget to moisturize. All right,
we'll come right back and we're gonnatalk about one of my favorite topics,
sagging skin, because I can't beatthat. Wrinkles are different, blatches are
different, melatonin you talked about,brown spots are different. This is a
sagging skin, and I don't wantto go under the knife, so you

(30:17):
guys don't go anywhere. Allo,man. But that doesn't bother me,
not even because I am happy anda freely admit I'm inappropriate for my age.
Dad, you may think that I'mall of it. That doesn't bother

(30:40):
me. Not even because I amhappy and are admin, I'm inappropriate.
Oh my age. Hello, Hello, Hello, this is Adrian Bergen.
This is Generation Bolt, the Fountainof truth, the fountain of truth about
aging. And people judge you.There's no doubt, they say, it

(31:02):
takes three seconds to judge somewhat.And one of those things they judge you
on is how old you are.And unfortunately, in an aged world,
they the golden thread between people thinkinghow old you are is how competent you
are? Can you do the work? Can you get the job? Should
they date you? Or should theyinvest in whatever your business is? Should
they use you as their doctor?All of these things come to play in

(31:26):
people's minds when they look at you. And therefore I cannot have a show
that tells you to go gray,look like who did it in Ran because
it's okay to look older. AndI do get a lot of pushback,
and I am called vain, andI guess I am, But the fact
is I do care about the wayI look. And now I'm learning from

(31:47):
our guest today, I amitate aShell, who's the co founder and CEO
of Young Goose, that there's ahealth component to it, not just a
vanity component. And he's been extremelyclear to us that the health of your
skin not just reflects the health ofthe rest of your body, but can
cause better or ill health to therest of your body. Now, his

(32:10):
research and his work is in topicalsthe kinds of things that can bring you,
in his view and his research,better health internally and externally. But
I gave him a challenge for thelast part of our show, and that
has to do with something I havenot been able to beat, which is
sagging skin, the con you seeunder your arms, the can you see

(32:32):
under your chin? So, amboy, first, tell everybody how to find
you, because they're going to wantto learn more about Young Goose. And
then is there any hope for that? The issues of saying so first,
how to find you? Okay,So to find us pretty pretty easy.
The name of the brand is YoungGoose and the name of our website is

(32:54):
young Goose dot com. And whereyou can find most of the knowledge mostly
most of the information is either onour Facebook or Instagram page, which both
of them. You can look forYoung Goose Skincare and you will find us.
Into your question, Yeah, thereis something to do about it.

(33:16):
So you mentioned sarcopenia, which whichis obviously loss of volume, volume and
sagging and obviously the like anywhere elsein the body where volume is an issue,
the problem is, or the challengeis stimulation and demand. The reason

(33:37):
that sagging skin is more prevalent,for example, on our face and arms
than in our legs, for example, is because there is more demand for
blood for nutrients in our legs thanin our arms our face. So what
I want to say here is thatby creating demand and by clearing some of

(33:59):
the things that we know are associatedwith higher sarcopedia prevalence as we grow older,
we can definitely not only prevent it, but also reverse some of the
some of the effects that that timehas kind of afflicted on the skin.

(34:19):
Two things especially, I don't knowif if you've talked on your show about
ages advanced glacation and products or glycationin general, but that is also called
the tenth hallmark of aging. Sothe first nine hallmarks were identified twenty thirteen
at the seminal paper in Cell magazine, but the one that they left out

(34:43):
was glacation, and that basically,in very short explanation, that represents the
cumulative glycemic and oxidative stress in ourbody, so like sugar and oxidative stress
in our body in general, butalso in our skin. Do you want
to just interrupt you here? Justfor our audience, we have a video

(35:07):
on the doctor near Brazilli and heis the head of aging research at Mount
Sinai and one of the leaders ingeroscience. Doing a tame study on met
Foreman with the FDA, and hedid a wonderful seminar for us online which

(35:27):
you'll find on YouTube and we'll findit on our website. We'll post it
on the eight net. At thattime was the eight Hallmarks of aging.
There now several others. We havenot talked about glacation. We must talk
about it right now. And somepeople now call it like we called about
inflammation. We talked about inflammating.Some people called glycan aging. Even so,

(35:52):
this is important. I will alsotell everybody that the FDA looks at
sarcopenia and how bad it is,which means saying skin as well as gate
speed as two of the greatest hallmarksof aging. And they're even talking about
having approval for drugs if one oftheir hallmarks, one of their benchmarks is

(36:15):
that it helps with circlopedia. That'show dangerous ceclopedia is as a signal.
It's not just a beauty issue.So you had two things that you had
in mind. One was glycan andyou were explaining that to us. So
let's go right back to that rightnow. Okay, So basically, glycation
means sugar molecules that attached to proteinsin our skin. Most of those proteins

(36:37):
are collagen. So when glycation happensin the skin, what happens is the
skin becomes more rigid, thinner,and also obviously more wrinkled, because a
rigid, less elastic skin is goingto get more wrinkled as time goes on.
And that's like a short discussion onglycation, which I would love to

(36:58):
expand on, but just for ourdiscussion, you can think of it as
rigid, thin, wrinkled skin.And there is a huge um correlation between
skin autofluorescence, which is the amountof glycation in the skin, and sarcopenia.
So if we can solve one,and we do have, we have

(37:21):
published studies on how we solve it, or how we target it for that
matter, and how that helps withskin laxity in general. Two products specifically,
or three actually now are our eyeCare, which is an eye product
ie cream that goes around the eye, it's not into the eye ProCare,

(37:45):
which is our synolytic serum, andthe hyperbaric mask which we mentioned. So
all those those three products are theleading products right now in the world as
far as we're concerned to counteract vacation. And you mentioned Neil beal Zuli,
which I don't know if your yourlisteners can detect from my accent. We're

(38:07):
both Israeli where we both conduct alot of our studies in the Hebrew University
in Jerusalem and the Weitzmann Institute,which are two very good research entities in
Israel. So having said that glaciationis one of the things that has a

(38:30):
huge effect on sarcopenia, the other, and I think probably more important as
far as addressing aging as a whole, is microcirculation. And if people remember,
if people were into counteracting skin agingtwenty years ago, there was a
fat of prescribing some heart medications forskin health and the reason is that they

(38:53):
increased blood supply to the skin throughmicrocirculation, and that then and and I
did mention demand before, so thatdemand for more blood in the skin will
also create demand for more blood inthe tissues that are kind of below the

(39:14):
skin, so our muscles, oursubcutaneous fat in our face. If we
talk about this face and arms,specifically face and arms, that's going to
create demand for blood in those tissues, and that means less degeneration. That
means more nutrients, more oxygen,which we mentioned, which means a healthier

(39:37):
tissue. And we've made the connectiontoday between a healthier, youthful tissue and
it's it's esthetic appearance. So youknow, I mentioned that oxygen facials oxygen
per se didn't do much for me, and you explain why, and it
isn't the infusion of oxygen. It'shelping the skin use the oxygen. Yeah.

(40:00):
But when I said that, Ialso there's a certain facials that did
help me. And people always askme what do you use, and I
never will answer because it may notbe the right thing for them, and
I'm not that kind of influencer.But I will say the one thing that
has helped me in facials and productsis microcurrent. And I'm wondering whether the

(40:21):
microcurrent devices and the microcurrent facials aredoing what you're talking about I really don't
know. Are they stimulating the skinfor more blood flow and therefore less sagging.
Is that the connection or is thereanother way to achieve that. First
of all, I'll be remissing remissif I didn't say that. If you
ask someone who has a financial interestvested in those procedures there, I bet

(40:45):
their their reaction is going to bedifferent. But if you're asking me,
they'd be very happy. They'd bevery happy that I use it. Yeah,
Well, my answer is yes.The reason is because normally when you
go through either you know, fatloss or facials that are using any kind

(41:05):
of electricity, the the marketing sideis going to tell you that it is
creating some kind of stimulation for repair, but that stimulation actually is very hard
to control. In ninety nine pointnine, maybe there's something that I don't
know, but I'm pretty versed inthat field, and what most of what
they do is they create short,short term contraction of micro muscles in the

(41:31):
skin or wherever else we're doing it, and that contraction pumps blood into the
area, which then brings nutrients andoxygen. So that's a huge part of
skin health and overall overall any tissuehealth Having said that, a lot of

(41:52):
you know, whether it is sarcopeniaor some other issues that are visible in
the skin, are for the moststart preventing necrosis, preventing cellular or tissue
death. So we're really kind ofalmost you can think of resuscitating the tissue
through doing that, and obviously combiningit with other things that do call for

(42:14):
renewal through inflammation in a very controlledfashion is a winning combination. Yeah.
So what I want to bring outhere is that it's not just all about
how you look looking younger, foolingpeople into thinking that you're younger, being
ashamed to look older, and thatisn't what this is about. And it's

(42:35):
not about narcissism or vanity. Itis finally seeing that whole holistic umbrella between
what you are on the inside andhow you look on the outside. And
I think that the reason the cosmeticindustry is such a vibrant industry is because
we kind of internally know it.We know that there's a connection between the

(42:57):
way we look on the outside andhow we feel the inside our overall health.
And it's wonderful to hear you explainit to us from a scientific point
of view. Not from an eightcosmetic hype point of view where they trying
to sell to sixty year olds byusing a model that's clearly already twenty years
old. You know it's enough.So thank you so much for being with

(43:19):
us. This has been more thanfascinating and I just can't wait to delve
into some other of the products.I'm the biggest guinea pig in the whole
world and actually feel on the outsideas young as I feel on the inside.
Thank you so much, Ammony.It's absolutely my pleasure. And for
everybody else we've been talking about younggoose, but you guys put on a

(43:44):
hat because you look much better ina hat after age seventy, I know
I do. And get out there, kids and make it hap