December 3, 2022 • 43 mins
Phil Newman is Editor-in-Chief Longevity.Technology and founder of First Longevity which brings together international investors and Longevity start-ups.
In his career, Phil has held c-level management positions; applying his marketing and business development expertise into these tech sectors: Longevity; IoT; AI; Medical Devices; Biopharma; 3D Manufacturing; Smartgrid and Sustainability.
In his career, Phil has held c-level management positions; applying his marketing and business development expertise into these tech sectors: Longevity; IoT; AI; Medical Devices; Biopharma; 3D Manufacturing; Smartgrid and Sustainability.
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Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
(00:08):
When I look in the mirror,I don't see wrinkles. When I look
in the mirror, I see hairon my head, not my shoulder.
Hello. Hello, Hello, Thisis Adrian Berger, and this is Generation
Bold, the Fountain of Truth,the fountain of truth about aging. And
(00:30):
one of the things that we helpyou do is make the connection between information
and attitude, information about aging,what was happening in the world of longevity,
health span, healthcare, and lifestyle, so that you change your attitude
about aging, so that the attitudeyou have is so much more contributory to
(00:52):
this world. You have more energy, and in fact, eventually, with
that information, you also live longer, because it is proven, there are
so many studies that show that abetter attitude toward your own future actually gives
you a longer future. So todayit's no surprise that one of our really
honored guests is Phil Newman, becausein his own way, he really is
(01:17):
a futurist. He is the editorin chief of Longevity Technology. He is
the founder of First Longevity, whichbrings international investors and longevity startups together,
and that means he has his eyeon the prize, he has his finger
on the pulse. I got youeverywhere working there, Phil, so that
(01:38):
we can understand what's new, what'shappening, what the future may bring in
the world of longevity. So thankyou for being with us today, phil
Agian is a pleasure, all right. So let's jump into this. We've
known each other for a long time. I've been watching longevity technology and reading
from the beginning probably and I'm seeingthis I would call this a snowball effect,
(02:01):
starting very small and over and overagain. I'm seeing more and more
companies, startups and actually very largecompanies going into the world of longevity technology.
But before we do anything, let'sexplain to the listeners what is longevity
technology so they understand it at abasic level. Sure, well, at
(02:22):
a basic level of longevity. DotTechnology is the domain address for our website.
So simply type in www Longevity Technologyand you'll find our website. And
really we see the website being aconduct for all of the interesting things that
are happening in the world of research, commerce, investment, and commercialization in
(02:47):
the field of longevity. And we'vedone a derivative of our website or producer
derivative, which is specifically focused onconsumers as well. So with regards to
the way that we are communicating inthe market. We're actually going to be
changing that up over the next fewmonths where we will be separating some of
the crossover content and working specifically intotwo domains, the business domain and the
(03:10):
consumer domain of longevity because the sectorhas grown into an industry now and we
need to kind of break the waywe communicate and evolve it over a period
of time. So that's what we'redoing right now. Are Drew And actually
I will tell you that some greatinvestors about five years ago or four years
ago said to me Adrian, longevityis not an industry, and those same
(03:31):
people today have changed their mind.So what does it mean to the consumer?
It means that more and more startupsare looking at products and services not
just healthcare, not just curative,not just medicine, but to prevent some
of the diseases of aging, tohelp you not just live longer, because
(03:51):
longevity seems like it's just about lengthof life, but in fact it's about
health of life too. So sinceyou see and report actually so many of
these things, Phil, is thereanything right now that's exciting to you the
most exciting? What are two thingsthat you're happening you're seeing happen in the
field of lungevity or lungevity technology.Yeah, well, to reflect what you
(04:15):
just said there, Adrian, wehave seen this transform into an industry now.
So when I looked back in twentyeighteen at the sector, it felt
a bit of a mess, andit felt like there was quite a lot
of rhetoric in the sector where peoplewere talking about living forever immortal immortalists,
and as well as people talking aboutliving to five hundred and six hundred thousand
(04:36):
years old. And you know,that's still valid in terms of people's perceptions
because we all need innovators and creativethinkers to help us move forward. But
also what's happened is that the sciencecommunity in the investment community has now come
in behind all of this because theycan really see that if we can help
people by living longer, more productive, healthier lives and staving off those diseases
(05:00):
of aging, then of course that'sgoing to be beneficial for everybody. The
trauma of cardiovascular disease on individuals,on their families, on the healthcare systems
that they're part of, as wellas Alzheimer's diabetes, all of these things
we can see that there are pathwaysnow to preventing these diseases from happening in
the first place, and in manyrespects, the way that the entity now
(05:25):
is calibrating itself and talking really isvery important to making a mainstream investment category
as well as mainstream products and consumercategories. So we see it's happening.
It's still early days, but whatwe found now really is that people are
now not just talking about their epigenetics, sorry, the genetics. They're now
talking about epigenetics, so which iswhat's above their genetics. So you know,
(05:46):
there's obviously what we're born with interms of our genetics, but likewise
it's there are our lifestyle and ourenvironment. And as a real development of
the wellness sector, people are reallystarting to switch into the that they need
to manage their their exercise, theirdiets, their sleep, and their stress
levels and unfortunately also for those toenjoy a drink, their alcohol consumption.
(06:11):
Those those five things will really helpyou calibrate your your baseline as an individual
to make sure that you live aslong as healthy as you possibly can.
Sollas I just want to pause herefrom me too to tell the folks that
there are two very important things embeddedin what Phil Newman is saying. And
remember this is a person who hasa three hundred and sixty degree view of
(06:34):
what has been a very chaotic,very complicated transformation in both industry, investing
and health. One is that wemoved. We moved from people who were
let's say, the visionaries, andmany of them were criticized because they would
(06:55):
talk about living forever, and soit was a very marginalized topic that people
who could giggle at, particularly ifyou were a geroscientist. And now that's
moved away from that to something veryconcrete, which is, we can live
much healthier, much longer. Wedon't have to be satisfied with getting Alzheimer's
or being proud that we could liveto eighty or eighty six. No,
(07:17):
it could be much longer than thatand healthy an industry, big money has
taken this up so that it's becominga sector. Do you remember the days
of biotech when you didn't know whatthat was, and now most of you
have those stocks in your regular iras. So this is what's happening, and
(07:38):
this is why I want you toknow about it as early as possible.
So let's get back. You weretalking about something, phil You were rattling
off sleep and you were rattling offyou know, good epigenetics, how your
genes express themselves. These are differentbiomarkers or hallmarks of aging. So what
are you seeing the industry, folks, of all these different hallmarks of aging
(08:01):
and a COVID brought up the immunesystem into everybody's consciousness. Where is that?
Add is there a particular focus inthese startups that one can invest in
or venture capitalists are investing in interms of the hallmarks of aging and preventing
some of these horrible diseases. Yes, of course. Well you're referring to
the hallmarks of aging, which therewere originally nine of them, and the
(08:24):
industry got very exercised about a yearago when there was the concept of the
tenth hallmark of aging perhaps coming intothe canon of hallmarks. Well, there
was a conference this year where theyadded more hallmarks of aging, and I
believe there are fifteen or sixteen ofthem now. So it shows you that
really the science started to move onand effectively these aging drivers, whether they
(08:50):
are a DNA repair, telomere regulation, glycination, these are all very highly
scientific terms. But they are,in fact as they are aging drivers,
and those aging drivers when you're inyour middle aged years, they become more
pervasive. You either get more ofthem or fewer of them as you get
(09:11):
older, and of course they becomeprecursors to the diseases of aging, which
are things like cardiovascular disease at Alzheimer'sand so on. So if as an
industry, we can start to identifyand manage those aging pathways and then workout
ways in which we can adjust them, dialing them down or dining them up,
(09:31):
we're able to really effectively keep peopleyounger metabolically, which means that if
you're perhaps you know, in yourlet's take myself, so I'm fifty five
and my chronological age is fifty five, but my metabolic age or my epigenetic
age is forty seven. So thatmeans that obviously, rather than being five
(09:54):
years away from the age of sixtywhen most of the diseases of aging start
to take hold, I'm actually thirteenyears away from them. Now. I'm
not going to stay away from sixtyforever metabolically, but the longer I can
do that, the better I'm goingto be in terms of my future health
and the future length of my life. And really I feel the key thing
(10:16):
that from a consumer perspective, froma human perspective, is the concept of
understanding the difference between your chronological ageand your medical biologe. So when we
come back, we're going to takea little bit of a break now and
we're going to hit just that.I'll also tell you about how I measure
my age. Phil, you're probablymeasuring your age. And we come back,
(10:39):
we're going to talk to Phil Newman, who's the editor in chief of
Luxevity Technology that's luxevity dat technology dotcom, founder of first Lungevity. Don't
talk about biomarkers, and we're goingto talk about biological clocks, which again
is rife with startups and new companiesthat are helping you measure these hallmarks of
(11:01):
aging. Is it something you cando in your home? Well, don't
you go anywhere, all of man, But that doesn't bother me, not
even a because I am happy anda fly I'm inappropriate for my aged You
(11:22):
may think that I'm all It doesn'tbother me, not even because I am
happy and I'm inappropriate. Oh myhello, hello, Hello, this is
Adrian bergand this is Generation boul theFountain of Truth, the Fountain of truth
(11:43):
about aging, and I'm going tocatch you up if you miss the first
section of our show. We're heretoday with Phil Newman. He is the
editor in chief of Longevity Technology.You can find it at www. Dot
Lungevity dot technology. Why would youwant to look well, because this is
the guy with a three hundred andsixty degree view of what's happening in the
(12:07):
world of investing in startups, what'snew, and what's going to affect your
life in the future when it comesto your own healthy aging. If you
take a look at our website Adrianbergdot com, you're going to see that
we are everywhere. We've archived allof our shows for the past four years,
including some very important award winning shows, and also gives you some instructions
(12:31):
on how to go to iTunes,iHeartRadio, wherever we're heard and give us
a very good rating. Is importantthat people know that they can control their
own long future, and we helpthem do that. So one of the
things that I've been doing is goingto conferences and Phil Newman was at one
of those important conferences called Ratfest andif you go to Adrianberg dot com and
(12:54):
you got to contact me. Iwill send you our audio and video reviews
of Radfest. That's one of theconferences that looks at longevity. It used
to be, phil something that wasvery marginal way out there, all about
longevity and immortality. But since youwere there for the four days that I
was, you see that it ismuch more science oriented and folks, if
(13:18):
you had been there, one ofthe things you would have seen was great
discussions on how to measure your ownhall marks of aging through biological clocks and
biomarkers. And there are so manypeople and companies going into that field right
now with startups and different types ofclocks, that soon it's going to be
(13:39):
confusing to us the consumer. Solet me throw this to you. Phil.
You talked about the hall marks ofaging. You said, we thought
that they were eight. Now wethink they are in ten. At this
conference they talked about fifteen. Wewould like to measure that the way we
measure our weight. Do you feel, looking at the new companies that this
is on the horizon and how shouldthe consumers start thinking about measuring their own
(14:03):
hallmarks of aging? Well, youcan measure your hallmarks of aging using a
product from a company called Ginfinity.They have a panel that offers the nine
hallmarks of aging, and that's atI believe the company is called by the
(14:24):
company's difficult Ginfinity, But I believeif you did a search on aging soos
you'll find their site. But that'sone avenue. But of course it doesn't
give you what would be the subjectof our earlier discussion, which is your
epigenetic age. So there are differenttests that are available to measure epigenetic age
using particularly called DNA methylation. Soyou could go to see a company called
(14:50):
True Diagnostic, which is TRAU Diagnostic. Then there's also the what's called the
Clock Foundation, and these are organizationsthat are working on helping people through a
blood blood draw to which you cando at home, to understand what they're
there by the chronological ages that theyhave at the time of their blood tests
(15:13):
and give you indications to if it'splus or minus your chronological age. Some
of the interventions that you can youcan you can implement to ensure that you're
helping to keep your health and longevityoptimized. So that's a very important part
of how people would start to calibratetheir their own behavior by by their their
(15:33):
metabolic age. But the reality isit's very new, it's a new science.
There was a conference that I wentto last week and Eric Dnn who
is the director of the Buck Institute, he did draw up some points said
(15:54):
that perhaps there are other ways thatneed to be looked at in terms of
these tests, and that maybe thesetests need to be validated in different ways.
Really, he was saying that theindustry is still very young, and
of course it will get better overa period of time in terms of its
accuracy. But this is a youngindustry. So it will get to a
point where the industry works on itsbaselines and creates a standard that everybody is
(16:18):
happy to work towards and as youdo in any industry, and then the
future will get to a point whereclinicians I have got bulletproof tests that can
measure people's age to help them identifywhether they're ahead or behind their their chronological
years. And I do feel thatonce people become aware of that, their
(16:40):
minds will be expanded to the possibilityof staying younger longer, And I feel
that that's going to be a veryimportant trigger point in the industry, we're
not there yet. Enthusiasts and earlyearly adopters like myself and yourself, Adrian,
we understand that. But for thisto get out into the wide community,
that's going to take a few yearsyet. But I would encourage people
to do it because it really doeshelp you understand where you are in your
(17:03):
own life. And for me,I'm seven. Sorry, I'm eight years
younger than my chronological years, butmy wife is actually ten years older.
So in many respects there's an eighteenyear difference between us now even though we
are we're born in the same year, So that gives you an idea of
how varied it can be. Andspeaking on behalf of my wife, she's
(17:25):
now had a bit of a shockwith that, and now she's looking at
ways in which she can bring downher metabolic age to be more accurately reflecting
her chronological age. Yes, andyou see one of the things that we
talk about all the time. We'vehad so many guests on the show,
and phil A. Noman just actuallyrattled it off at our first segment.
There are things that we call gerointerventions, things that you can do to
(17:48):
get a little bit younger biologically andthose other things your mother told you to
do. Exercise, eat right,get good sleep, have a life purpose.
I get their energy back in yourmake sure your vitamins are right.
I'm not talking about fancy nutraceuticals.That's a whole other topic. But make
sure that you when you go toyour doctor and it gives you your blood
levels and he says you're down onmagnesium, you take care of yourself.
(18:11):
All of those things, particularly theexercise and the right nutrition, can keep
you younger longer. What is happeningfor the consumer without their knowledge? Think
of a world where there was nosuch thing as the bathroom scale, where
you could not weigh yourself, oryou had to spend a ton of money
(18:32):
to go to some special place toweigh you or to know your BMI.
Well, this is what biomarkers,in my opinion, and biological clocks are
going to become. Eventually, peoplewill have them, they'll be part of
They'll be like Siri, tell mehow old I am today. It's going
to happen, and it's going tohappen through longevity technology, and everyone will
know about it. Take it forgranted, but I want us to know
(18:56):
about it early, and it isabsolutely true, your right, Phil.
I use two very simple cheap things. One is a scale that tells me
my metabolic age, and the otherone is a blood test series, which
actually medicare covers. By the way, people don't know this, but yes,
and I have two different ages.One is sixty six and one is
(19:18):
seventy one. I'm actually seventy five, so I'm happy with both of them.
But but they are different, andthat's because there are different kinds of
clocks measuring different things, the differentkinds of accuracy. So don't get too
excited the way Phil Newman says,longevity technology is on the job to weed
out what's right and to entice theright investors for the right kinds of new
(19:41):
companies. I just want you toknow what's on the horizon we come back.
I want to talk to you,Phil about the greatest problem that we
face today in aging, and thenof course is Alzheimer's. While money is
put into that and anything else,and I really want your opinion as to
whether we're getting anywhere, So youguys, do not go anywhere. We'll
be right back, hello, man. But that doesn't bother me, not
(20:03):
even because I am happy and I'minappropriate for my age. Dad. You
may think that I'm all of it. Don't bother me, not even because
I am happy and I'm inappropriate.Oh my, and hello, Hello,
(20:33):
Hello, This is Adrian Bergend isGeneration Bold, the Fountain of Truth,
the fountain of truth about aging nowvery recently, and you may be hearing
this next year because we Arclive allof our shows, and so does iTunes
and so does iHeartRadio. But intwenty twenty two October, they were too
important conferences and they're very different.One is red Fest, which actually has
(20:57):
an attitude that we can become mortal. Yet they deal with the day to
day geroscience that will make us livelonger, not forever, and healthier.
The other conference is a conference ofjust generally all geoscientists are usually listened to
(21:17):
by other geroscientists, very technical,called the Catalis Institute and met Obesity Targeting.
Metabesity is their conference, and theywere almost back to back, and
for two years I helped found andcreate the conferences for the Catalis Institute.
In both of these conferences we hada terrific speaker, Phil Newman, and
(21:38):
he's our guest today who really seesthe industry of longevity through Longevity Technology.
Please take a look at Longevity dotTechnology if you want to learn more about
his newsletter and his work. Andalso as the founder of First Longevity,
which takes a look at startups,brings the's almost like a matchmaker, bringing
(22:00):
investors the right kind of investors tothese startups. Eventually, longevity will become
an investment sector for all of us, just like healthcare is, and biotech
is, and you know fuel is. It will become one of those sectors
that your advisor is going to tellyou to invest it. But are these
(22:22):
are early stages, and as welook at what's on the market, we
also begin to look at what's availableto us. So one of those things
is groups of measurers like biomarkers andbio clocks. Another, of course,
are ways of gerro intervention reversing someof the bad signs of aging we already
(22:44):
have once we know we have them. But if you take a look at
the money that's spent by the NIANational Institute on Aging NIAGED National Institute on
Health, it's all about Alzheimer's.So I'm going to throw this tough one
to you, Phil, and thatis what's happening in the field. Is
anybody coming up with a startup ornot such a startup that you think is
really going to intervene and help uswith the scourge of aging which is Alzheimer's.
(23:11):
Yes, Well, there's there's anorganization of a company, biotech company
called Biogen, which is a verybig, big nest that quoted company and
in partnership with a Japanese biotech calledEsai. They have announced that they've had
very positive results from their clinical studyof just under two thousand participants about helping
(23:37):
them with early early Alzheimer's disease soearly mild cognitive impairment, and of course
that is very encouraging. It's beenquite quite a contentious discovery process that they've
been through. There are a lotof people that felt that the FDA fast
tracked the approval process. Other peoplefelt it was valid. At the end
(24:00):
of the day, is the datathat does the talking, and so far
their clinical data is looking very positiveand of course that will need to go
through the regulatory peer review process andbe accepted by the FDA formally, but
really that will be the first drugthat we see on the market that is
available to people to help with earlyonset Alzheimer's. Of course, we want
(24:21):
to be in a position really wherewe can catch Alzheimer's. Well, first
of all, we can prevent Alzheimersfrom happening in the first place, which
is what I was referring to earlier, where we're looking at these aging drivers
and really understanding can we can wemitigate any of those early signals of disease
creation and hit them before they actuallybecome anything to be concerned about. But
(24:41):
likewise, diagnostics is a very importantpart of understanding. You know, are
you in a position where you're goingto be at risk? So you know
there are Alzheimer's genes which you canget tested for. And I've had a
recently had a brain scan, hadan MRI scan of my brain which then
went through a company's process. Thecompanies called brain key. So if you
(25:07):
get a brain ky dot AI youcan see where they where you can get
clinical support. But basically at theend of the day, I had a
three D brain scan and a lotof the physical attributes that a brain would
have that would give indication to somebodyof me being fifty five, that you
have a downstream concern. Both myparents once died of Alzheimer's and one has
(25:29):
Alzheimer's. So it's a big thingfor me as an individual. So far,
so good. I'm showing pretty wellthat they're my brain's in good condition
and that I don't have anything toworry about at this time. So now,
one of those things, Phil I'llsay is there's controversy over whether you
should know early on any of thesethings. Of course, you and me
(25:51):
we have the same view, isthat you should that if you can detect
anything earlier, you're better off.But let you say with the Alzheimer's,
there's nothing you can do about it, but that is not true. There's
a lot of slowing processes that canbe done. There's a lot of medications
even with this particular disease. Now, now let's go back to you with
(26:11):
regard to that, and that isprice. I'm going to go right to
the jugular. I have also hadan MRI, but it was covered because
it was because I'm a medicare andcertain things allow to be covered. But
if I took that or got athree D and went to that company,
it would be on private pay.Where do you see that happening? Where
(26:36):
do you see the payers coming inin these startups and you know, the
future companies, so that it's there'ssome equity in being able to access these
helpful, preventative and curative new longevitydevices and protocols. Well. Interestingly,
(26:56):
the insurance sector is really starting toget into this now, because when you
have a life insurance company, ofcourse they want you to stay long lived
and healthy for as long as possible. It's absolutely within their benefit if they
can, if they can help youto do so. So we are finding
(27:18):
now that epigenetic testing is now startingto get into the insurance sector, which
is the life insurance sector, notthe health insurance sector. But people are
starting to get it in terms ofhelping people early to prevent those downstream issues.
And really what we'll find in thefuture is that healthcare systems will start
(27:38):
to switch more to preventative strategies thandisease management strategies. Really, the current
paradigm that unfortunately we're all stuck inis that the healthcare system one disease at
a time. And obviously the conceptof fixing disease as an aging as a
(28:00):
disease is one of those things thatpeople get very exercise about in our industry.
The FDA doesn't classify aging as adisease, and it's one of those
points that perhaps they never will maybethey'll get there one day, but really
aging is a syndrome of many things, And of course what you want to
(28:21):
be in a position of doing isreally understanding what are your weak points for
you metabolically, so you can getahead of fixing those as you go forward.
And really what will happen is asthe as the healthcare system matures into
really considering disease prevention as being actuallya beneficial to their beneficial thing to their
profit lines as well as their customers, that they'll they'll start to switch around.
(28:45):
And of course understanding how the UShealthcare system works. Of course,
if you if you have a disease, then you'll have an allowable code.
And if a doctor gets paid forfulfilling an allowable code, books gets ticked,
payments are made, everybody's happy.So therefore the infrastructure and the mindset
sitting behind most healthcare systems at thisstage, it is really kind of the
(29:07):
wrong way for where we want tobe able to be sick. Yeah,
I always say that here in theUS, it's terrible place to stay well,
it's an excellent place to be sickbecause there they will bring in all
the forces to help you. Butthere's very little covered for prevention. And
that is changing, you know,because we are in the field of aging
here and so medic care is comingup with some interesting things. But the
(29:32):
reason I want all the listeners toknow about longevity dot technology just www dot
longevity dot technology is, for example, it's there that I first read about
the fact that some insurance companies willactually pay for your biomarker tests and so
on. Why because they want youto know where you're at so that you
can do something about it, sothat they don't have to pay off so
(29:55):
fast because you're living longer and they'rekeeping your premium's longer. So it's a
win when that combination. But asPhil Newman just said, it's not health
insurance that is getting into the act, it's life insurance companies that's getting into
the act, and eventually annuity companies. So very interesting, uh, combination
(30:15):
between science industry and your own personalfinances. The rubber meets the road there.
Now when we come back, we'regoing to put the pill on the
spot. He already disclosed to usthat he is many years younger biologically than
he is chronologically, and I'm goingto ask what he does about it,
(30:37):
and I'm going to give you alittle tease. I asked him about exercise
during the a little break and hegave me an answer that shocked me.
So don't you go anywhere. Butthat doesn't bother me. And I'm inappropriate
(30:59):
for my ag You don't bother me, not because I am happy. I'm
inappropriate. And hello, Hello,Hello, this is Adrian Bergen. This
(31:22):
is Generation bout the Fountain of Truth, the Fountain of truth about aging.
And you can get information on ourblogs. There's about three or four years
of blogs if you take a lookat adrianberg dot com, maybe four years
of our weekly podcasts on adrianburg dotcom. But if you use iTunes or
(31:44):
iHeartRadio or lips in or Google podcasts, we're on all of those. So
please take a look at Please giveus a good rating, because I want
this information out to the public.We have also just become disseminated on baby
boomer dot org. Baby boomer dotorg. There are many, many,
many members who do not have thisinformation. Is so much out there about
(32:07):
aging and it is all negative.It is all you're gonna get Alzheimer's or
is all about silly things. AndI know I get criticized, but silly
things like pickle ball. There isnow a book and I think it is
aptly named pickle Ball for Dummies.I'm actually going to ask the author of
(32:27):
that to be on my show.But he also has a podcast and the
name of his podcast is I Usedto Be Somebody. It's nice name,
funny name, but I'll tell youthe truth. I want us to still
be somebody that I used to besomebody, and I'll be challenging him if
he's willing to come on my show. Right now, I have with may
Phil Newman, who is the editorin chief of Longevity Technology. Take a
(32:51):
look at Longevity dot Technology and you'llfind plenty of information. He is also
the leader, I think in lookingat startups and bringing them together with investors
called first longevity. To me,I am telling you about something as if
you heard that the world is notflat, the world is round for the
first time. But I think it'sgoing to become a knowledge. I'm just
(33:14):
bringing all this information to you earlier. And one of the things that Phil
and I do is we measure ourbiology where we are biologically with regard to
our age, not just chronological.And people always ask me, what do
you do? What do you use? So I'm going to turn the tables,
Phil I ask you what do youdo to be so much younger biologically
(33:37):
than you are chronologically? And Ithought you were going to say exercise,
but you didn't, So tell uswhat that's all about. Sure, well,
I have. I used to doa lot of very extreme endurance sports,
cycling and swimming mainly, so youknow, I've swum long distances,
(33:58):
you know, from Asia to Europeand the English Channel, and I've I've
cycled the length of the Pyrenees,and I've done lots of crazy things.
And I actually overdid it. Igot to the point where I got a
virus and I didn't actually get tothe point where I've ever really got rid
of that virus. So I havechronic fatigue, which in the advent of
(34:21):
COVID is now called long COVID.It's just a similar, similar thing with
a different pathology. But at theend of the day, I'm not in
a position where I can exercise.So really, while I've been pursuing my
career in longevity. I've been notexercising, so I can tell you right
now, Adrian, that nothing todo with my longevity is to do with
(34:43):
exercising, because I do very little. I can perhaps do fifteen minutes of
my old exercise in the pool oron an exercise bike. So the question
becomes what is it? Is itneutraceuticals, is it better eating, is
intermittent fasting? All the above?Yep, it's all of the above.
So I did actually have some testsdone, so I have a personalized vitamin
(35:07):
regime, which is including the thingsthat you appreciate. You know. It's
got vitamin vitamin D three in thereand coqu ten and omiga three, all
of the things that you would know. But likewise, I've got some other
things in there, like lu tothion boosters. I also use an NMN
(35:28):
product which is a nat plus precursor, and in fact I toddled between nm
N and n R two different waysto improve your nat plus levels, which
obviously fall away as you get older. These are niacins, by the way,
folks, These are niacins. Youcan get them in any store,
but in terms of dosage, interms of effectiveness, they're all different.
(35:50):
Company is different. That's another show. We will have what neutraceutical to buy
because we're inundated with that now inour regular pharmacies or online, and they
are better and worse products. Soright now, because they're not FDA regulated
in the same way as drugs,there is some regulation, we really don't
know what to take. We knowwe should take something, but we don't
(36:10):
know what. And so this iswhat what Phil has done. He's gotten
himself a personalized program, which ofcourse also costs somebody. So I'm trying
to get I called precision neutrosuticals freefor everybody, but I don't know.
I have the last long time tomake that happen. So you have the
(36:30):
neutrosuticles, go ahead, and whatelse turns the tide for you other than
since you're not really exercise. Yeah, well, interestingly, I was vegetarian
all my adult life, from frombeing sixteen through to being what would be
now fifty two fifty three. SoI've been eating protein through through meats over
(36:52):
the last year and a half,which has helped me. I would imagine
it feels like the right proteins aregoing into my body now. I do
follow intermittent fastly, but not religiously. I mean, I know a lot
of people perhaps do an eight hourfast, worth they only eat for eight
hours in the day, so theymay start have their first meal at twelve
midday and have their last piece offood at eight pm in the evening.
(37:13):
You know, I do follow that, but I don't follow that religiously.
I'll wake up in the morning andthink, yeah, you know, I'm
not feeling too hungry today, andthen what I'll do is not eating until
till early afternoon. And those thingscombined with obviously just really ensuring that if
I can keep my stress levels down, keep my alcohol down, and really,
(37:34):
at this stage, I just keepit, keep it as controlled as
possible, which it is easy tosay and it's hard to do sometimes,
but I would highly recommend to peoplethat they do think about what they're actually
putting in their bodies in terms ofnutrition. So I had a draw and
a covered full of all the bitterbins that I thought I should be taking
because of various articles I've read orconversations with friends who have said, oh,
(37:59):
you know, you should take this. It's wonders for me. The
reality is if you if you're notactually understanding whether it is working wonders for
you. You can fill yourself upwith hundreds of pills during a month and
you don't really know whether they're workingfor you or not. So I would
recommend working with a nutritionalist and understandingare you eating the right things and are
you supplementing the right way. It'sa good thing to do. And I
(38:21):
do get a personalized month. Supplyof personalized vitamins arrive through my door every
every every month, and I'd sayit's cheaper than actually going into the store
and buying ten different products to supplementme for for a month. Yes,
my journey has been in and alot of people are on the same journey
(38:43):
I was. At first. Ijust took vitam. It was like Omega
three. And my mom was thefirst, one of the first responders in
terms of nutraceuticals. She used tosay I have the healthiest closet in America.
And the reason she said that wasshe would buy all the stuff but
never taken so that I had hadthe healthiest closet in America. And I
started to do that. Every timeI'd read an article, I'd say,
(39:06):
oh, I need that, andI would pay fifteen to sixty dollars for
thirty or sixty days supply, andI began to realize that I was duplicating,
that there were some different things thesame things in different and I made
a real chart about it. Ihave not yet had a precision look at
what I should be taking, butthat is definitely a group of companies are
(39:30):
now on the market where they dothat for a price. I don't know,
Phil, I'll ask you whether you'vecovered any of those, whether some
of those companies that do the precisionwork for you some names should like,
we do not take any compensation forany of this, So I don't have
any qualms of asking you to namesome companies. Sure well, so in
(39:52):
the UK. The company I workwith in the UK is specifically just UK
based at this stage because obviously you'reyou're giving guidance, you need to be
licensed in the right country to beable to do so. But very impressed
with a company called biome vi omso if iome offer a number of different
tests and then they offer you thesupplement regime that follows after that. So
(40:15):
they're very oriented with the microbiome towhat's going on in your gut. That's
why, Yeah, that's correct,Yeah, exactly. And they do have
longevity utility, of course in theprescriptions that they offer, prescriptions, excuse
me, the supplements that they offer. But yes, that's one organization that
(40:37):
i'd encourage people to take a lookat. Yeah. So we have a
dilemma here, and that is alot of these things are not as FDA
regulated as prescription, and so wedon't know, we don't know how viable,
how accurate, how important. Andon the other hand, do we
want them so regulated so that ittakes years and years to get the right
(41:00):
kind of prescription approved. It's areal problem, the issue of regulation.
I always wish that there was somethinglike the old days, the good housekeeping
seal of approval. Looking at someof these different tests nutraceuticals and even vitamins
that people are taking. We're goingto be delving into that because it is
(41:21):
certainly a great area of consumer confusion. But as we wrap this up today,
this is what I want you toknow. There are folks like Phil
Newman who have devoted their careers becauseof a realization that longevity and aging does
not have to be a problem.It could actually be the solution because it
(41:44):
gives you more and more years tolove your life and accomplish what you want
to accomplish, and seize the futureof aging being much longer and healthier than
we have it today. And whilewe're all looking at things like how are
we spend our next ten years offifteen years in retirement, maybe we should
(42:06):
be thinking about how are we goingto spend our next thirty or forty years
and not retire because we will beso strong and so with it that we
can continue to be contributor tory tothe world. So, Phil, I
hope you find the great startups andI hope that you find the investors to
do this, because this is reallyfor us. So thank you for what
(42:28):
you're doing. Phil. Oh,it's a pleasure. And you know,
the next Google, the next Appleis going to be in this space.
It's going to happen. And Ithink that's in a hundred years from now,
we will look back on the waythat we carry our lives out and
how we live and how we retire, and I think we will look upon
it as being something that's better resignedto history. So yeah, I mean
(42:50):
it's going to happen. Yes,So I thank you so much. And
for everybody else, I'm going tosay the same thing, and there's a
lot of meaning in this. WhatI mean is make the world sorry if
they don't see you as contributory.As we grow older, the world doesn't
expect much of us. Make themsorry. So I will end this show
as I always do. Get outthere, kids and make it happen.
When I look in the mirror,I don't see wrinkles. When I look
in the mirror, I see hairon my head, not my shoulder.
Hello. Hello, Hello, Thisis Adrian Berger, and this is Generation
Bold, the Fountain of Truth,the fountain of truth about aging. And
(00:30):
one of the things that we helpyou do is make the connection between information
and attitude, information about aging,what was happening in the world of longevity,
health span, healthcare, and lifestyle, so that you change your attitude
about aging, so that the attitudeyou have is so much more contributory to
(00:52):
this world. You have more energy, and in fact, eventually, with
that information, you also live longer, because it is proven, there are
so many studies that show that abetter attitude toward your own future actually gives
you a longer future. So todayit's no surprise that one of our really
honored guests is Phil Newman, becausein his own way, he really is
(01:17):
a futurist. He is the editorin chief of Longevity Technology. He is
the founder of First Longevity, whichbrings international investors and longevity startups together,
and that means he has his eyeon the prize, he has his finger
on the pulse. I got youeverywhere working there, Phil, so that
(01:38):
we can understand what's new, what'shappening, what the future may bring in
the world of longevity. So thankyou for being with us today, phil
Agian is a pleasure, all right. So let's jump into this. We've
known each other for a long time. I've been watching longevity technology and reading
from the beginning probably and I'm seeingthis I would call this a snowball effect,
(02:01):
starting very small and over and overagain. I'm seeing more and more
companies, startups and actually very largecompanies going into the world of longevity technology.
But before we do anything, let'sexplain to the listeners what is longevity
technology so they understand it at abasic level. Sure, well, at
(02:22):
a basic level of longevity. DotTechnology is the domain address for our website.
So simply type in www Longevity Technologyand you'll find our website. And
really we see the website being aconduct for all of the interesting things that
are happening in the world of research, commerce, investment, and commercialization in
(02:47):
the field of longevity. And we'vedone a derivative of our website or producer
derivative, which is specifically focused onconsumers as well. So with regards to
the way that we are communicating inthe market. We're actually going to be
changing that up over the next fewmonths where we will be separating some of
the crossover content and working specifically intotwo domains, the business domain and the
(03:10):
consumer domain of longevity because the sectorhas grown into an industry now and we
need to kind of break the waywe communicate and evolve it over a period
of time. So that's what we'redoing right now. Are Drew And actually
I will tell you that some greatinvestors about five years ago or four years
ago said to me Adrian, longevityis not an industry, and those same
(03:31):
people today have changed their mind.So what does it mean to the consumer?
It means that more and more startupsare looking at products and services not
just healthcare, not just curative,not just medicine, but to prevent some
of the diseases of aging, tohelp you not just live longer, because
(03:51):
longevity seems like it's just about lengthof life, but in fact it's about
health of life too. So sinceyou see and report actually so many of
these things, Phil, is thereanything right now that's exciting to you the
most exciting? What are two thingsthat you're happening you're seeing happen in the
field of lungevity or lungevity technology.Yeah, well, to reflect what you
(04:15):
just said there, Adrian, wehave seen this transform into an industry now.
So when I looked back in twentyeighteen at the sector, it felt
a bit of a mess, andit felt like there was quite a lot
of rhetoric in the sector where peoplewere talking about living forever immortal immortalists,
and as well as people talking aboutliving to five hundred and six hundred thousand
(04:36):
years old. And you know,that's still valid in terms of people's perceptions
because we all need innovators and creativethinkers to help us move forward. But
also what's happened is that the sciencecommunity in the investment community has now come
in behind all of this because theycan really see that if we can help
people by living longer, more productive, healthier lives and staving off those diseases
(05:00):
of aging, then of course that'sgoing to be beneficial for everybody. The
trauma of cardiovascular disease on individuals,on their families, on the healthcare systems
that they're part of, as wellas Alzheimer's diabetes, all of these things
we can see that there are pathwaysnow to preventing these diseases from happening in
the first place, and in manyrespects, the way that the entity now
(05:25):
is calibrating itself and talking really isvery important to making a mainstream investment category
as well as mainstream products and consumercategories. So we see it's happening.
It's still early days, but whatwe found now really is that people are
now not just talking about their epigenetics, sorry, the genetics. They're now
talking about epigenetics, so which iswhat's above their genetics. So you know,
(05:46):
there's obviously what we're born with interms of our genetics, but likewise
it's there are our lifestyle and ourenvironment. And as a real development of
the wellness sector, people are reallystarting to switch into the that they need
to manage their their exercise, theirdiets, their sleep, and their stress
levels and unfortunately also for those toenjoy a drink, their alcohol consumption.
(06:11):
Those those five things will really helpyou calibrate your your baseline as an individual
to make sure that you live aslong as healthy as you possibly can.
Sollas I just want to pause herefrom me too to tell the folks that
there are two very important things embeddedin what Phil Newman is saying. And
remember this is a person who hasa three hundred and sixty degree view of
(06:34):
what has been a very chaotic,very complicated transformation in both industry, investing
and health. One is that wemoved. We moved from people who were
let's say, the visionaries, andmany of them were criticized because they would
(06:55):
talk about living forever, and soit was a very marginalized topic that people
who could giggle at, particularly ifyou were a geroscientist. And now that's
moved away from that to something veryconcrete, which is, we can live
much healthier, much longer. Wedon't have to be satisfied with getting Alzheimer's
or being proud that we could liveto eighty or eighty six. No,
(07:17):
it could be much longer than thatand healthy an industry, big money has
taken this up so that it's becominga sector. Do you remember the days
of biotech when you didn't know whatthat was, and now most of you
have those stocks in your regular iras. So this is what's happening, and
(07:38):
this is why I want you toknow about it as early as possible.
So let's get back. You weretalking about something, phil You were rattling
off sleep and you were rattling offyou know, good epigenetics, how your
genes express themselves. These are differentbiomarkers or hallmarks of aging. So what
are you seeing the industry, folks, of all these different hallmarks of aging
(08:01):
and a COVID brought up the immunesystem into everybody's consciousness. Where is that?
Add is there a particular focus inthese startups that one can invest in
or venture capitalists are investing in interms of the hallmarks of aging and preventing
some of these horrible diseases. Yes, of course. Well you're referring to
the hallmarks of aging, which therewere originally nine of them, and the
(08:24):
industry got very exercised about a yearago when there was the concept of the
tenth hallmark of aging perhaps coming intothe canon of hallmarks. Well, there
was a conference this year where theyadded more hallmarks of aging, and I
believe there are fifteen or sixteen ofthem now. So it shows you that
really the science started to move onand effectively these aging drivers, whether they
(08:50):
are a DNA repair, telomere regulation, glycination, these are all very highly
scientific terms. But they are,in fact as they are aging drivers,
and those aging drivers when you're inyour middle aged years, they become more
pervasive. You either get more ofthem or fewer of them as you get
(09:11):
older, and of course they becomeprecursors to the diseases of aging, which
are things like cardiovascular disease at Alzheimer'sand so on. So if as an
industry, we can start to identifyand manage those aging pathways and then workout
ways in which we can adjust them, dialing them down or dining them up,
(09:31):
we're able to really effectively keep peopleyounger metabolically, which means that if
you're perhaps you know, in yourlet's take myself, so I'm fifty five
and my chronological age is fifty five, but my metabolic age or my epigenetic
age is forty seven. So thatmeans that obviously, rather than being five
(09:54):
years away from the age of sixtywhen most of the diseases of aging start
to take hold, I'm actually thirteenyears away from them. Now. I'm
not going to stay away from sixtyforever metabolically, but the longer I can
do that, the better I'm goingto be in terms of my future health
and the future length of my life. And really I feel the key thing
(10:16):
that from a consumer perspective, froma human perspective, is the concept of
understanding the difference between your chronological ageand your medical biologe. So when we
come back, we're going to takea little bit of a break now and
we're going to hit just that.I'll also tell you about how I measure
my age. Phil, you're probablymeasuring your age. And we come back,
(10:39):
we're going to talk to Phil Newman, who's the editor in chief of
Luxevity Technology that's luxevity dat technology dotcom, founder of first Lungevity. Don't
talk about biomarkers, and we're goingto talk about biological clocks, which again
is rife with startups and new companiesthat are helping you measure these hallmarks of
(11:01):
aging. Is it something you cando in your home? Well, don't
you go anywhere, all of man, But that doesn't bother me, not
even a because I am happy anda fly I'm inappropriate for my aged You
(11:22):
may think that I'm all It doesn'tbother me, not even because I am
happy and I'm inappropriate. Oh myhello, hello, Hello, this is
Adrian bergand this is Generation boul theFountain of Truth, the Fountain of truth
(11:43):
about aging, and I'm going tocatch you up if you miss the first
section of our show. We're heretoday with Phil Newman. He is the
editor in chief of Longevity Technology.You can find it at www. Dot
Lungevity dot technology. Why would youwant to look well, because this is
the guy with a three hundred andsixty degree view of what's happening in the
(12:07):
world of investing in startups, what'snew, and what's going to affect your
life in the future when it comesto your own healthy aging. If you
take a look at our website Adrianbergdot com, you're going to see that
we are everywhere. We've archived allof our shows for the past four years,
including some very important award winning shows, and also gives you some instructions
(12:31):
on how to go to iTunes,iHeartRadio, wherever we're heard and give us
a very good rating. Is importantthat people know that they can control their
own long future, and we helpthem do that. So one of the
things that I've been doing is goingto conferences and Phil Newman was at one
of those important conferences called Ratfest andif you go to Adrianberg dot com and
(12:54):
you got to contact me. Iwill send you our audio and video reviews
of Radfest. That's one of theconferences that looks at longevity. It used
to be, phil something that wasvery marginal way out there, all about
longevity and immortality. But since youwere there for the four days that I
was, you see that it ismuch more science oriented and folks, if
(13:18):
you had been there, one ofthe things you would have seen was great
discussions on how to measure your ownhall marks of aging through biological clocks and
biomarkers. And there are so manypeople and companies going into that field right
now with startups and different types ofclocks, that soon it's going to be
(13:39):
confusing to us the consumer. Solet me throw this to you. Phil.
You talked about the hall marks ofaging. You said, we thought
that they were eight. Now wethink they are in ten. At this
conference they talked about fifteen. Wewould like to measure that the way we
measure our weight. Do you feel, looking at the new companies that this
is on the horizon and how shouldthe consumers start thinking about measuring their own
(14:03):
hallmarks of aging? Well, youcan measure your hallmarks of aging using a
product from a company called Ginfinity.They have a panel that offers the nine
hallmarks of aging, and that's atI believe the company is called by the
(14:24):
company's difficult Ginfinity, But I believeif you did a search on aging soos
you'll find their site. But that'sone avenue. But of course it doesn't
give you what would be the subjectof our earlier discussion, which is your
epigenetic age. So there are differenttests that are available to measure epigenetic age
using particularly called DNA methylation. Soyou could go to see a company called
(14:50):
True Diagnostic, which is TRAU Diagnostic. Then there's also the what's called the
Clock Foundation, and these are organizationsthat are working on helping people through a
blood blood draw to which you cando at home, to understand what they're
there by the chronological ages that theyhave at the time of their blood tests
(15:13):
and give you indications to if it'splus or minus your chronological age. Some
of the interventions that you can youcan you can implement to ensure that you're
helping to keep your health and longevityoptimized. So that's a very important part
of how people would start to calibratetheir their own behavior by by their their
(15:33):
metabolic age. But the reality isit's very new, it's a new science.
There was a conference that I wentto last week and Eric Dnn who
is the director of the Buck Institute, he did draw up some points said
(15:54):
that perhaps there are other ways thatneed to be looked at in terms of
these tests, and that maybe thesetests need to be validated in different ways.
Really, he was saying that theindustry is still very young, and
of course it will get better overa period of time in terms of its
accuracy. But this is a youngindustry. So it will get to a
point where the industry works on itsbaselines and creates a standard that everybody is
(16:18):
happy to work towards and as youdo in any industry, and then the
future will get to a point whereclinicians I have got bulletproof tests that can
measure people's age to help them identifywhether they're ahead or behind their their chronological
years. And I do feel thatonce people become aware of that, their
(16:40):
minds will be expanded to the possibilityof staying younger longer, And I feel
that that's going to be a veryimportant trigger point in the industry, we're
not there yet. Enthusiasts and earlyearly adopters like myself and yourself, Adrian,
we understand that. But for thisto get out into the wide community,
that's going to take a few yearsyet. But I would encourage people
to do it because it really doeshelp you understand where you are in your
(17:03):
own life. And for me,I'm seven. Sorry, I'm eight years
younger than my chronological years, butmy wife is actually ten years older.
So in many respects there's an eighteenyear difference between us now even though we
are we're born in the same year, So that gives you an idea of
how varied it can be. Andspeaking on behalf of my wife, she's
(17:25):
now had a bit of a shockwith that, and now she's looking at
ways in which she can bring downher metabolic age to be more accurately reflecting
her chronological age. Yes, andyou see one of the things that we
talk about all the time. We'vehad so many guests on the show,
and phil A. Noman just actuallyrattled it off at our first segment.
There are things that we call gerointerventions, things that you can do to
(17:48):
get a little bit younger biologically andthose other things your mother told you to
do. Exercise, eat right,get good sleep, have a life purpose.
I get their energy back in yourmake sure your vitamins are right.
I'm not talking about fancy nutraceuticals.That's a whole other topic. But make
sure that you when you go toyour doctor and it gives you your blood
levels and he says you're down onmagnesium, you take care of yourself.
(18:11):
All of those things, particularly theexercise and the right nutrition, can keep
you younger longer. What is happeningfor the consumer without their knowledge? Think
of a world where there was nosuch thing as the bathroom scale, where
you could not weigh yourself, oryou had to spend a ton of money
(18:32):
to go to some special place toweigh you or to know your BMI.
Well, this is what biomarkers,in my opinion, and biological clocks are
going to become. Eventually, peoplewill have them, they'll be part of
They'll be like Siri, tell mehow old I am today. It's going
to happen, and it's going tohappen through longevity technology, and everyone will
know about it. Take it forgranted, but I want us to know
(18:56):
about it early, and it isabsolutely true, your right, Phil.
I use two very simple cheap things. One is a scale that tells me
my metabolic age, and the otherone is a blood test series, which
actually medicare covers. By the way, people don't know this, but yes,
and I have two different ages.One is sixty six and one is
(19:18):
seventy one. I'm actually seventy five, so I'm happy with both of them.
But but they are different, andthat's because there are different kinds of
clocks measuring different things, the differentkinds of accuracy. So don't get too
excited the way Phil Newman says,longevity technology is on the job to weed
out what's right and to entice theright investors for the right kinds of new
(19:41):
companies. I just want you toknow what's on the horizon we come back.
I want to talk to you,Phil about the greatest problem that we
face today in aging, and thenof course is Alzheimer's. While money is
put into that and anything else,and I really want your opinion as to
whether we're getting anywhere, So youguys, do not go anywhere. We'll
be right back, hello, man. But that doesn't bother me, not
(20:03):
even because I am happy and I'minappropriate for my age. Dad. You
may think that I'm all of it. Don't bother me, not even because
I am happy and I'm inappropriate.Oh my, and hello, Hello,
(20:33):
Hello, This is Adrian Bergend isGeneration Bold, the Fountain of Truth,
the fountain of truth about aging nowvery recently, and you may be hearing
this next year because we Arclive allof our shows, and so does iTunes
and so does iHeartRadio. But intwenty twenty two October, they were too
important conferences and they're very different.One is red Fest, which actually has
(20:57):
an attitude that we can become mortal. Yet they deal with the day to
day geroscience that will make us livelonger, not forever, and healthier.
The other conference is a conference ofjust generally all geoscientists are usually listened to
(21:17):
by other geroscientists, very technical,called the Catalis Institute and met Obesity Targeting.
Metabesity is their conference, and theywere almost back to back, and
for two years I helped found andcreate the conferences for the Catalis Institute.
In both of these conferences we hada terrific speaker, Phil Newman, and
(21:38):
he's our guest today who really seesthe industry of longevity through Longevity Technology.
Please take a look at Longevity dotTechnology if you want to learn more about
his newsletter and his work. Andalso as the founder of First Longevity,
which takes a look at startups,brings the's almost like a matchmaker, bringing
(22:00):
investors the right kind of investors tothese startups. Eventually, longevity will become
an investment sector for all of us, just like healthcare is, and biotech
is, and you know fuel is. It will become one of those sectors
that your advisor is going to tellyou to invest it. But are these
(22:22):
are early stages, and as welook at what's on the market, we
also begin to look at what's availableto us. So one of those things
is groups of measurers like biomarkers andbio clocks. Another, of course,
are ways of gerro intervention reversing someof the bad signs of aging we already
(22:44):
have once we know we have them. But if you take a look at
the money that's spent by the NIANational Institute on Aging NIAGED National Institute on
Health, it's all about Alzheimer's.So I'm going to throw this tough one
to you, Phil, and thatis what's happening in the field. Is
anybody coming up with a startup ornot such a startup that you think is
really going to intervene and help uswith the scourge of aging which is Alzheimer's.
(23:11):
Yes, Well, there's there's anorganization of a company, biotech company
called Biogen, which is a verybig, big nest that quoted company and
in partnership with a Japanese biotech calledEsai. They have announced that they've had
very positive results from their clinical studyof just under two thousand participants about helping
(23:37):
them with early early Alzheimer's disease soearly mild cognitive impairment, and of course
that is very encouraging. It's beenquite quite a contentious discovery process that they've
been through. There are a lotof people that felt that the FDA fast
tracked the approval process. Other peoplefelt it was valid. At the end
(24:00):
of the day, is the datathat does the talking, and so far
their clinical data is looking very positiveand of course that will need to go
through the regulatory peer review process andbe accepted by the FDA formally, but
really that will be the first drugthat we see on the market that is
available to people to help with earlyonset Alzheimer's. Of course, we want
(24:21):
to be in a position really wherewe can catch Alzheimer's. Well, first
of all, we can prevent Alzheimersfrom happening in the first place, which
is what I was referring to earlier, where we're looking at these aging drivers
and really understanding can we can wemitigate any of those early signals of disease
creation and hit them before they actuallybecome anything to be concerned about. But
(24:41):
likewise, diagnostics is a very importantpart of understanding. You know, are
you in a position where you're goingto be at risk? So you know
there are Alzheimer's genes which you canget tested for. And I've had a
recently had a brain scan, hadan MRI scan of my brain which then
went through a company's process. Thecompanies called brain key. So if you
(25:07):
get a brain ky dot AI youcan see where they where you can get
clinical support. But basically at theend of the day, I had a
three D brain scan and a lotof the physical attributes that a brain would
have that would give indication to somebodyof me being fifty five, that you
have a downstream concern. Both myparents once died of Alzheimer's and one has
(25:29):
Alzheimer's. So it's a big thingfor me as an individual. So far,
so good. I'm showing pretty wellthat they're my brain's in good condition
and that I don't have anything toworry about at this time. So now,
one of those things, Phil I'llsay is there's controversy over whether you
should know early on any of thesethings. Of course, you and me
(25:51):
we have the same view, isthat you should that if you can detect
anything earlier, you're better off.But let you say with the Alzheimer's,
there's nothing you can do about it, but that is not true. There's
a lot of slowing processes that canbe done. There's a lot of medications
even with this particular disease. Now, now let's go back to you with
(26:11):
regard to that, and that isprice. I'm going to go right to
the jugular. I have also hadan MRI, but it was covered because
it was because I'm a medicare andcertain things allow to be covered. But
if I took that or got athree D and went to that company,
it would be on private pay.Where do you see that happening? Where
(26:36):
do you see the payers coming inin these startups and you know, the
future companies, so that it's there'ssome equity in being able to access these
helpful, preventative and curative new longevitydevices and protocols. Well. Interestingly,
(26:56):
the insurance sector is really starting toget into this now, because when you
have a life insurance company, ofcourse they want you to stay long lived
and healthy for as long as possible. It's absolutely within their benefit if they
can, if they can help youto do so. So we are finding
(27:18):
now that epigenetic testing is now startingto get into the insurance sector, which
is the life insurance sector, notthe health insurance sector. But people are
starting to get it in terms ofhelping people early to prevent those downstream issues.
And really what we'll find in thefuture is that healthcare systems will start
(27:38):
to switch more to preventative strategies thandisease management strategies. Really, the current
paradigm that unfortunately we're all stuck inis that the healthcare system one disease at
a time. And obviously the conceptof fixing disease as an aging as a
(28:00):
disease is one of those things thatpeople get very exercise about in our industry.
The FDA doesn't classify aging as adisease, and it's one of those
points that perhaps they never will maybethey'll get there one day, but really
aging is a syndrome of many things, And of course what you want to
(28:21):
be in a position of doing isreally understanding what are your weak points for
you metabolically, so you can getahead of fixing those as you go forward.
And really what will happen is asthe as the healthcare system matures into
really considering disease prevention as being actuallya beneficial to their beneficial thing to their
profit lines as well as their customers, that they'll they'll start to switch around.
(28:45):
And of course understanding how the UShealthcare system works. Of course,
if you if you have a disease, then you'll have an allowable code.
And if a doctor gets paid forfulfilling an allowable code, books gets ticked,
payments are made, everybody's happy.So therefore the infrastructure and the mindset
sitting behind most healthcare systems at thisstage, it is really kind of the
(29:07):
wrong way for where we want tobe able to be sick. Yeah,
I always say that here in theUS, it's terrible place to stay well,
it's an excellent place to be sickbecause there they will bring in all
the forces to help you. Butthere's very little covered for prevention. And
that is changing, you know,because we are in the field of aging
here and so medic care is comingup with some interesting things. But the
(29:32):
reason I want all the listeners toknow about longevity dot technology just www dot
longevity dot technology is, for example, it's there that I first read about
the fact that some insurance companies willactually pay for your biomarker tests and so
on. Why because they want youto know where you're at so that you
can do something about it, sothat they don't have to pay off so
(29:55):
fast because you're living longer and they'rekeeping your premium's longer. So it's a
win when that combination. But asPhil Newman just said, it's not health
insurance that is getting into the act, it's life insurance companies that's getting into
the act, and eventually annuity companies. So very interesting, uh, combination
(30:15):
between science industry and your own personalfinances. The rubber meets the road there.
Now when we come back, we'regoing to put the pill on the
spot. He already disclosed to usthat he is many years younger biologically than
he is chronologically, and I'm goingto ask what he does about it,
(30:37):
and I'm going to give you alittle tease. I asked him about exercise
during the a little break and hegave me an answer that shocked me.
So don't you go anywhere. Butthat doesn't bother me. And I'm inappropriate
(30:59):
for my ag You don't bother me, not because I am happy. I'm
inappropriate. And hello, Hello,Hello, this is Adrian Bergen. This
(31:22):
is Generation bout the Fountain of Truth, the Fountain of truth about aging.
And you can get information on ourblogs. There's about three or four years
of blogs if you take a lookat adrianberg dot com, maybe four years
of our weekly podcasts on adrianburg dotcom. But if you use iTunes or
(31:44):
iHeartRadio or lips in or Google podcasts, we're on all of those. So
please take a look at Please giveus a good rating, because I want
this information out to the public.We have also just become disseminated on baby
boomer dot org. Baby boomer dotorg. There are many, many,
many members who do not have thisinformation. Is so much out there about
(32:07):
aging and it is all negative.It is all you're gonna get Alzheimer's or
is all about silly things. AndI know I get criticized, but silly
things like pickle ball. There isnow a book and I think it is
aptly named pickle Ball for Dummies.I'm actually going to ask the author of
(32:27):
that to be on my show.But he also has a podcast and the
name of his podcast is I Usedto Be Somebody. It's nice name,
funny name, but I'll tell youthe truth. I want us to still
be somebody that I used to besomebody, and I'll be challenging him if
he's willing to come on my show. Right now, I have with may
Phil Newman, who is the editorin chief of Longevity Technology. Take a
(32:51):
look at Longevity dot Technology and you'llfind plenty of information. He is also
the leader, I think in lookingat startups and bringing them together with investors
called first longevity. To me,I am telling you about something as if
you heard that the world is notflat, the world is round for the
first time. But I think it'sgoing to become a knowledge. I'm just
(33:14):
bringing all this information to you earlier. And one of the things that Phil
and I do is we measure ourbiology where we are biologically with regard to
our age, not just chronological.And people always ask me, what do
you do? What do you use? So I'm going to turn the tables,
Phil I ask you what do youdo to be so much younger biologically
(33:37):
than you are chronologically? And Ithought you were going to say exercise,
but you didn't, So tell uswhat that's all about. Sure, well,
I have. I used to doa lot of very extreme endurance sports,
cycling and swimming mainly, so youknow, I've swum long distances,
(33:58):
you know, from Asia to Europeand the English Channel, and I've I've
cycled the length of the Pyrenees,and I've done lots of crazy things.
And I actually overdid it. Igot to the point where I got a
virus and I didn't actually get tothe point where I've ever really got rid
of that virus. So I havechronic fatigue, which in the advent of
(34:21):
COVID is now called long COVID.It's just a similar, similar thing with
a different pathology. But at theend of the day, I'm not in
a position where I can exercise.So really, while I've been pursuing my
career in longevity. I've been notexercising, so I can tell you right
now, Adrian, that nothing todo with my longevity is to do with
(34:43):
exercising, because I do very little. I can perhaps do fifteen minutes of
my old exercise in the pool oron an exercise bike. So the question
becomes what is it? Is itneutraceuticals, is it better eating, is
intermittent fasting? All the above?Yep, it's all of the above.
So I did actually have some testsdone, so I have a personalized vitamin
(35:07):
regime, which is including the thingsthat you appreciate. You know. It's
got vitamin vitamin D three in thereand coqu ten and omiga three, all
of the things that you would know. But likewise, I've got some other
things in there, like lu tothion boosters. I also use an NMN
(35:28):
product which is a nat plus precursor, and in fact I toddled between nm
N and n R two different waysto improve your nat plus levels, which
obviously fall away as you get older. These are niacins, by the way,
folks, These are niacins. Youcan get them in any store,
but in terms of dosage, interms of effectiveness, they're all different.
(35:50):
Company is different. That's another show. We will have what neutraceutical to buy
because we're inundated with that now inour regular pharmacies or online, and they
are better and worse products. Soright now, because they're not FDA regulated
in the same way as drugs,there is some regulation, we really don't
know what to take. We knowwe should take something, but we don't
(36:10):
know what. And so this iswhat what Phil has done. He's gotten
himself a personalized program, which ofcourse also costs somebody. So I'm trying
to get I called precision neutrosuticals freefor everybody, but I don't know.
I have the last long time tomake that happen. So you have the
(36:30):
neutrosuticles, go ahead, and whatelse turns the tide for you other than
since you're not really exercise. Yeah, well, interestingly, I was vegetarian
all my adult life, from frombeing sixteen through to being what would be
now fifty two fifty three. SoI've been eating protein through through meats over
(36:52):
the last year and a half,which has helped me. I would imagine
it feels like the right proteins aregoing into my body now. I do
follow intermittent fastly, but not religiously. I mean, I know a lot
of people perhaps do an eight hourfast, worth they only eat for eight
hours in the day, so theymay start have their first meal at twelve
midday and have their last piece offood at eight pm in the evening.
(37:13):
You know, I do follow that, but I don't follow that religiously.
I'll wake up in the morning andthink, yeah, you know, I'm
not feeling too hungry today, andthen what I'll do is not eating until
till early afternoon. And those thingscombined with obviously just really ensuring that if
I can keep my stress levels down, keep my alcohol down, and really,
(37:34):
at this stage, I just keepit, keep it as controlled as
possible, which it is easy tosay and it's hard to do sometimes,
but I would highly recommend to peoplethat they do think about what they're actually
putting in their bodies in terms ofnutrition. So I had a draw and
a covered full of all the bitterbins that I thought I should be taking
because of various articles I've read orconversations with friends who have said, oh,
(37:59):
you know, you should take this. It's wonders for me. The
reality is if you if you're notactually understanding whether it is working wonders for
you. You can fill yourself upwith hundreds of pills during a month and
you don't really know whether they're workingfor you or not. So I would
recommend working with a nutritionalist and understandingare you eating the right things and are
you supplementing the right way. It'sa good thing to do. And I
(38:21):
do get a personalized month. Supplyof personalized vitamins arrive through my door every
every every month, and I'd sayit's cheaper than actually going into the store
and buying ten different products to supplementme for for a month. Yes,
my journey has been in and alot of people are on the same journey
(38:43):
I was. At first. Ijust took vitam. It was like Omega
three. And my mom was thefirst, one of the first responders in
terms of nutraceuticals. She used tosay I have the healthiest closet in America.
And the reason she said that wasshe would buy all the stuff but
never taken so that I had hadthe healthiest closet in America. And I
started to do that. Every timeI'd read an article, I'd say,
(39:06):
oh, I need that, andI would pay fifteen to sixty dollars for
thirty or sixty days supply, andI began to realize that I was duplicating,
that there were some different things thesame things in different and I made
a real chart about it. Ihave not yet had a precision look at
what I should be taking, butthat is definitely a group of companies are
(39:30):
now on the market where they dothat for a price. I don't know,
Phil, I'll ask you whether you'vecovered any of those, whether some
of those companies that do the precisionwork for you some names should like,
we do not take any compensation forany of this, So I don't have
any qualms of asking you to namesome companies. Sure well, so in
(39:52):
the UK. The company I workwith in the UK is specifically just UK
based at this stage because obviously you'reyou're giving guidance, you need to be
licensed in the right country to beable to do so. But very impressed
with a company called biome vi omso if iome offer a number of different
tests and then they offer you thesupplement regime that follows after that. So
(40:15):
they're very oriented with the microbiome towhat's going on in your gut. That's
why, Yeah, that's correct,Yeah, exactly. And they do have
longevity utility, of course in theprescriptions that they offer, prescriptions, excuse
me, the supplements that they offer. But yes, that's one organization that
(40:37):
i'd encourage people to take a lookat. Yeah. So we have a
dilemma here, and that is alot of these things are not as FDA
regulated as prescription, and so wedon't know, we don't know how viable,
how accurate, how important. Andon the other hand, do we
want them so regulated so that ittakes years and years to get the right
(41:00):
kind of prescription approved. It's areal problem, the issue of regulation.
I always wish that there was somethinglike the old days, the good housekeeping
seal of approval. Looking at someof these different tests nutraceuticals and even vitamins
that people are taking. We're goingto be delving into that because it is
(41:21):
certainly a great area of consumer confusion. But as we wrap this up today,
this is what I want you toknow. There are folks like Phil
Newman who have devoted their careers becauseof a realization that longevity and aging does
not have to be a problem.It could actually be the solution because it
(41:44):
gives you more and more years tolove your life and accomplish what you want
to accomplish, and seize the futureof aging being much longer and healthier than
we have it today. And whilewe're all looking at things like how are
we spend our next ten years offifteen years in retirement, maybe we should
(42:06):
be thinking about how are we goingto spend our next thirty or forty years
and not retire because we will beso strong and so with it that we
can continue to be contributor tory tothe world. So, Phil, I
hope you find the great startups andI hope that you find the investors to
do this, because this is reallyfor us. So thank you for what
(42:28):
you're doing. Phil. Oh,it's a pleasure. And you know,
the next Google, the next Appleis going to be in this space.
It's going to happen. And Ithink that's in a hundred years from now,
we will look back on the waythat we carry our lives out and
how we live and how we retire, and I think we will look upon
it as being something that's better resignedto history. So yeah, I mean
(42:50):
it's going to happen. Yes,So I thank you so much. And
for everybody else, I'm going tosay the same thing, and there's a
lot of meaning in this. WhatI mean is make the world sorry if
they don't see you as contributory.As we grow older, the world doesn't
expect much of us. Make themsorry. So I will end this show
as I always do. Get outthere, kids and make it happen.
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