February 23, 2025 • 25 mins
As the holiday season approaches, the pressure to shed extra pounds intensifies. Many are turning to trendy weight loss solutions like GLP-1 inhibitors—such as Ozempic and Wegovy—hoping for rapid results. But at what cost? While these medications have gained popularity for their effectiveness, experts warn that they come with hidden risks that could compromise long-term health.With nearly 100 million Americans struggling with obesity, GLP-1 inhibitors seem like a quick fix. However, could this shortcut to weight loss be trading pounds for health problems? Let’s explore the lesser-known dangers of these medications and how you can protect your well-being.The Silent Dangers of GLP-1 Inhibitors—and How to Mitigate Them1. Gastrointestinal Issues: More Than Just an Upset StomachWhy It Matters: Many dismiss nausea or vomiting as minor inconveniences. But did you know these symptoms could point to something much more severe?The Risk: GLP-1 drugs can lead to gastroparesis—a condition where the stomach doesn’t empty properly. This can result in chronic digestive issues that might become irreversible.What You Can Do:
Become a supporter of this podcast: https://www.spreaker.com/podcast/late-night-health-radio--2804369/support.
- Start Slow: Doctors should begin with the lowest possible dose, increasing gradually while monitoring for symptoms.
- Stay Hydrated and Eat Fiber: Patients can manage mild gastrointestinal issues by staying hydrated and incorporating a fiber-rich diet.
- Exercise Matters: Weight-bearing exercises can help, though not everyone can stick with them.
- Consider Fortetropin: This natural bioactive compound from fertilized egg yolk has shown promising results. A recent study by the University of California, Berkeley revealed an 18% increase in muscle protein synthesis in adults aged 66—even without exercise. Available exclusively through healthcare practitioner lines like MYOS MD, Fortetropin could be a valuable addition to your weight loss plan.
- Understand the Risks: Patients should fully comprehend the intended use of GLP-1 drugs and the consequences of off-label use.
- Prioritize Lifestyle Changes: Balanced nutrition and regular exercise remain the most sustainable solutions for long-term weight management.
- Stay Connected: Open conversations with healthcare providers about mental health symptoms are vital.
- Seek Support: Incorporate stress-reducing activities like mindfulness, yoga, or counseling into your routine to manage mood and anxiety.
Become a supporter of this podcast: https://www.spreaker.com/podcast/late-night-health-radio--2804369/support.
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Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:08):
This is Late Night Health. This is the radio show
that cares about the most important part of.
Speaker 2 (00:15):
Your life, your health.
Speaker 1 (00:17):
During the next hour, the Insane Daryl Wayne and I
yet don't ask it he is He and I are
going to take a look at some things that touch
each and every one of us. During the second part
of our show, we're going to take a look at
a new company that was founded by professors from Harvard
(00:41):
to take a look at supplements and test their effectiveness.
And so that's happening in about a half hour from now.
Right now, we're going to go to New York. I
believe we're going to New York or New Jersey, either
one of those places, and we're going to be speaking
with doctor Swa and doctor Swathy Buranasi DS. I think
(01:06):
I got that pretty close, and we're going to be
talking about trading pounds for health problems. Doctor Swanthy, Welcome
to Late Night Health.
Speaker 3 (01:14):
Thank you so much for having me our pleasure.
Speaker 2 (01:18):
So Americans are fat and overweight, There's just no doubt
about it.
Speaker 1 (01:26):
I recently lost twelve pounds and I'm very happy with that,
but another fifteen would be nice. Is it hard to
lose weight in general?
Speaker 3 (01:38):
It is hard to lose weight, and a lot of
that honestly comes down to the food system itself and
what sorts of foods are readily available, and also what
sorts of foods are easily accessible. So I mean readily available,
easy to grab in the grocery store, but I also
mean readily available like the oftentimes foods that are less
(01:59):
expensive are the ones that are not so great for us.
So those two pairing together just can make it very
difficult for the average American to lose weight.
Speaker 1 (02:11):
Food is medicine, and this is a fairly common concept
in the last ten years or so. Would you agree
with that, then, that food is medicine.
Speaker 3 (02:24):
I would agree that food should be viewed as medicine,
as you know, it can have medicinal value. Of course,
it you know, can taste delicious as well, so it's
not just something that we can use for our health.
It's also something that we can enjoy. But I think
that the average American now is starting to think, Okay,
what I'm putting in my body three times a day,
(02:45):
maybe even more often with snacks and beverages really is
impacting my mood and the way that I look and
feel about myself.
Speaker 1 (02:54):
Soft drinks come to mind, and kids, I remember, you know,
as a kid, Coca cola was a treat.
Speaker 2 (03:04):
It wasn't a daily experience, right, Is that still okay?
Once in a.
Speaker 1 (03:09):
While, you have a coke, a pepsi, if you prefer
orange soda, whatever it might be, is that okay? I mean,
I know they're loaded with with the terrible, terrible sugars,
but is it okay once in a while.
Speaker 3 (03:27):
So I always say moderation is best because let's say,
you know, especially when I used to work with patients
one on one, if patients absolutely loved their diet coke,
or they loved their orange soda or you know, fill
in the blank with you know that their you know,
pop or soda of choice. I always said, you know,
I'm not asking you to completely remove it from your diet,
(03:50):
but instead of drinking it every day, let's first start
with once a week, and then let's maybe see if
we can cut down to twice a month or even
once a month. So I think if your body is
not as used to it, your body doesn't crave it
as much. So it's more of that tapering phenomenon rather
than you know, cutting it off and then people crave it,
and then they go back to it, and sometimes they
(04:11):
even they even consumer or something more right. So it's
more about moderation. I don't want people to cut out
things that give them happiness, but at the same time,
we do need to recognize that consuming those things regularly
is really not the best for our health.
Speaker 1 (04:29):
As a As a doctor of pharmacy, you're known as
the integrated pharmacist. What is a food that you know
is not healthy for you, that you crave you love X?
What is X for swathy?
Speaker 3 (04:50):
For me, it has to be some sort of almond
croissant or pistachio croissant, something like that, where you know
it's filled with butter, but at the end of the day,
you know it something I let myself eat, Like monthly,
there's a really good croissant place around the street, and
you know, every month or so, I'm like, oh, the
month is almost suberg Did I have my croissant? So
it's it's not something that I'm cutting out completely, but
(05:14):
definitely something I look forward to and have in moderation.
Speaker 2 (05:17):
Do you have kids? No?
Speaker 3 (05:19):
I don't.
Speaker 1 (05:20):
No, you don't. Well, you can always adopt me with kids,
you know, especially kid number two. Kid number one, you know,
you drop something on the floor and you throw it away.
Kid number two, there's a ten second rule. Okay, you
can eat it. It's only ten seconds. I know the
(05:41):
dog just licked the floor.
Speaker 2 (05:42):
It's okay.
Speaker 1 (05:43):
My point is that should we be teaching our kids
proper eating habits so that they don't need to lose
weight when they're adults.
Speaker 3 (06:01):
I would say yes. And I think that is because
you know, first and foremost kids are going to learn
from their parents, and it's behaviors. It's you know, and
behaviors could be you know, eating behavior, but it also
could be you know, behavior pertaining to movement or mindfulness
or you know, the way that we approach problems. So
I think that's where it all starts and that's the
(06:22):
root of it. But at the end of the day,
you know, the kids are going to make their own
decisions once they leave the house and head to college
or technical school or work wherever they decide to go.
So I think instilling some of those principles early is
the best that parents can do.
Speaker 1 (06:37):
Teenage obesity is also on a ride on the rise,
and I think part of that, to me is because
they don't. They're not as active as I was as
a kid. Not that I'm active now, but when I
was a kid, I'd ride my bike all over the place, right,
we played in the street.
Speaker 2 (06:56):
Kids don't do that as much.
Speaker 3 (06:58):
It's true that they don't, and that's because of the
prevalence of screens. Everyone has, you know, at least what
is the stat like two to four screens per human
or something in the US as the average. So you know,
people are using not only their phones, they have laptops,
they have iPads, they have kindles, you know, all these
things that you know, don't really require any movement to use.
(07:19):
And so I think now they've grown up with the
you know, iPhones in their hands and looking at iPads
starting age too, and so they don't really see the
value in it, simply because it's not the way the
culture is molded right now.
Speaker 1 (07:33):
The we're coming up on the holidays and we are
going to start seeing during the holidays several things. We're
going to be seeing ads for all kinds of foods, chocolate, wine,
perfume that has absolutely nothing to do with our conversation,
but the ads for perfumes will also permeate the airwaves permeate.
Speaker 2 (07:56):
In their nevermind.
Speaker 1 (08:01):
And also we'll start seeing ads for join this gym
only nineteen dollars a month or a dollar to get
in whatever.
Speaker 2 (08:11):
And I know that a lot.
Speaker 1 (08:14):
Of people join the gym make a promise to themselves
how important is it to use that gym membership.
Speaker 3 (08:25):
So the thing is, it's not really about the gym
membership itself. It's more of how can we all find
movement that brings us joy. I think for some people
that is the gym, maybe that's the treadmill, it's lifting weights,
working with a trainer. But for others, especially a lot
of patients that are interested in the GLP one inhibitors
that will talk about they are patients that are either
(08:48):
already overweight or obese, and maybe they're not used to
as much activity. So maybe for them a gym membership
is not going to be as valuable, and instead, for
them it's taking a walk around the block, taking their
dog on a walk, you know, walking to you know,
grab the mail, like those sorts of things, just starting small,
because as I was saying with moderation with food, it's
(09:11):
it's not about changing your whole lifestyle overnight. And so
how can we start small and find something that you know,
our patients like or that people like, and then from
there we can grow and add things. But what I
don't want is people to all of a sudden think
that they need to be doing sixty minute you know,
high intensity interval training, you know, six times a week
(09:34):
or something like that.
Speaker 1 (09:35):
Do you do that kind of high intensity workouts yourself?
Speaker 3 (09:40):
So I don't do high intensity, but I do low intensity.
I really like reformer plates, so I do that. And
then I love long walk, So even if the weather's
not great, put on the scarf, put on the boots,
and I love going on a long walk and catching
up on a podcast or calling.
Speaker 1 (09:55):
My mom, gotcha? And I love walking in Manhattan. I
don't walk as much here in southern California as I
probably should. Our guest is doctor Swathy. She's an integrated pharmacist.
We're going to take some time out. When we come back.
I want to talk about some of the.
Speaker 2 (10:15):
New drugs that are available.
Speaker 1 (10:21):
Some of them are quite expensive. In fact, I think
most of them are quite expensive, and find out if
one they work, two if they're safe, and three if
there are alternatives to help people lose fifteen to twenty
even fifty pounds, so that'll be coming up.
Speaker 2 (10:41):
By the way.
Speaker 1 (10:42):
You can visit us at Latenighthealth dot com. Latenighthealth dot com.
You'll see pretty pictures.
Speaker 2 (10:49):
Of Darryl and me and even our guests like doctor Swathy.
Don't go away. As Late Night Health continues.
Speaker 4 (11:06):
Late Night Help is proud of our partnership with the EBC,
the Evolutionary Business Council. Check them out at Ebcouoncil dot com.
Speaker 5 (11:16):
You're listening to Late Night Help with Mark Allen. The
show continues in a moment.
Speaker 1 (11:25):
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She gave me a hearing examine, then showed me how
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Speaker 5 (12:26):
If you're listening to Late Night Health right now, you're
part of the growing target of baby boomers. Worth serving.
Speaker 6 (12:31):
Hi.
Speaker 5 (12:31):
I'm Darryl Wayne, producer of Late Night Health, inviting you
to join the Late Night Health family. If you have
any business targeting the growing boomer market, Late Night Health
is the ideal advertising vehicle for you. From vitamins to insurance,
alternative health, the Western style medicine, Late Night Health caters
to the growing population of those over forty years old.
This vibrant demographic has expendable income to fight aging, purchase travel,
(12:55):
take care of aging parents, or just have fun. Find
out about the advertising opportunities with Late Night Help. Call
us at oh five three nine one zero three zero eight.
That's aight. Oh five three nine one oh three oh eight,
or email us at info at Latenighthelp dot com. That's
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(13:15):
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Call now at at oh five three nine one zero
three zero eight. That's aight. O five three nine one
oh three o eight.
Speaker 6 (13:26):
Sometimes it's not what you say, it's how you say it.
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Speaker 1 (13:55):
It's time to tackle a tough topic, one that affects
us all. We're talking talking about sexism in the workplace.
The award winning Identifying the Elephant in the Room series
is back and ready to tackle some complicated communications issues
again this spring we're focusing on critical communication strategies in
the face of sexism.
Speaker 5 (14:15):
Join us as we.
Speaker 4 (14:16):
Hear from professionals in the natural products industry who have
valuable career lessons to share and real world experience to
discuss from all sides of the elephant. It's time to
have an honest and open conversation about the impact of
sexism in the workplace and how we can make it
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(14:37):
starts March sixteenth. Register today at nisibox dot vfares dot com.
That's I ni ci vo x dot v fai rs
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the solution.
Speaker 1 (14:55):
Late Night Health continues. I'm Mark Allen along with the
insane darrow Way. Our guest is doctor Swathy the Rahnessy Dias.
Did I blew that one? Let's try it again. Pronounce
your middle you're part of your last.
Speaker 3 (15:16):
Name for us, So yes, it's on doctor Swathy Varanasidias.
Speaker 2 (15:20):
That's easier said than done.
Speaker 1 (15:22):
All right, let's talk about what we said before the break,
and that is, you know, there's some new drugs that
really apparently work and you can drop you know, fifty
pounds or more safe quickly?
Speaker 2 (15:39):
Are these drugs safe?
Speaker 3 (15:44):
So that's the big question, and I think that's what's
getting lost in translation with the discussion of this new
class of drugs. And I see that they're news and
they've been FDA approved. They're called GLP one inhibitors, or
the longer term for that is glucle gone like peptide
one inhibitors. So the way that they work in the
body is that they increase insulin secretion, they reduce glucagon secretion,
(16:09):
and that results in lowering blood sugar levels. And initially
they were researched and discovered for their use in type
two diabetes, and that's how they became popular. Now they're realizing,
oh wow, actually patients who are taking these medications lose
a significant amount of weight, up to fifteen percent of
(16:29):
their weight for some patients, and so they're realizing that
there's opportunities to use this medication and other contexts. So
a lot of people are looking at it as a
quick fix, as a magic bullet, and I think that's
one of my concerns as an integrated pharmacist with the
use of this medication is that you know, everyone thinks, oh,
(16:50):
I can use it and it's the right fit for everyone,
which I also don't agree with. And that also we
can use it all of a sudden lose this weight
and then not have side effects.
Speaker 2 (17:01):
But there are side effects.
Speaker 3 (17:03):
Yes, exactly. So I would say there are four major
red flags associated with these GLP one inhibitors. The first
one is GI issues, So this is gastrointestinal issues stomach
related issues. This could be nausea, vomiting, constipation, and issues
with the stomach not emptying properly, which could lead to
(17:25):
other chronic issues like you know, gastroparesis for example. The
second one is accelerated muscle loss. So this is the
one that I don't see anyone else talking about yet,
and I'm sure it'll be popular soon, but at least
for now. You know, when people are losing weight on
these medications, you know, people are losing fat, but they're
(17:45):
also losing muscle, and so that is something of importance,
especially as we're all aging and we need to figure out,
you know, how we are going to preserve this muscle
that really lends itself to longevity and age powerfully. So
those two are very important. The other two is the
off label misuse so this is you know, patients who
(18:07):
are not technically eligible for the drug in terms of
the way it has been FDA approved. So there's you know,
in this class, it's ozembig, we go V Manjarro. There
are a lot of different medications that are in this class.
Speaker 1 (18:22):
But and this is I think the overariuses or the
misuse is the person may not may be overweight but
not have diabetes so exactly.
Speaker 3 (18:34):
So actually, like for exam, for example, we go V
is FDA approved for patients that are overweight but then
have some sort of comorbid condition, so they have some
sort of other chronic disease state that could make their
type two diabetes worse. Or the patient has a BMI
of over thirty, which is classified as obese. And so
(18:54):
for those patients, those are the patients in which it's
been researched, it's been FDA approved. However, a lot of
patients that are taking it are not falling into those
two categories. And so that's what I mean by off
label misuse is that you know, we actually don't have
the empirical data to say, yes, we should use it
in these patients, but a lot of the data has
(19:15):
been you know, kind of extrapolated from these other patient populations,
and then patients who are maybe not in need of
it so to speak, are using it. And then the
fourth red flag to just round out the top four
is mental health side effects. So patients have reported you know,
changes in mood swings and also you know, the lack
(19:37):
of reward or excitement when it comes to eating food.
Speaker 1 (19:42):
Wow, are there supplements that will help people lose weight
drop weight.
Speaker 2 (19:52):
That don't have side effects?
Speaker 1 (19:54):
Now, everything has side effects, we know that, but at
least they'll be there, they're mild side effects.
Speaker 3 (20:04):
So while there are supplements that are on the market
right now that are being marketed as GLP one alternatives
or substitutes or natural versions, and this, that and the other.
You know, at the end of the day, I'm a pharmacist,
so I'm always looking for where is your data, where
is your research to support the use of these And honestly,
(20:24):
do you have head to head studies that demonstrate that
this supplement is as effective or you know, maybe just
a little bit less effective or more effective than this
class of medication. So at this time, I have not
found a supplement that does that. However, if a patient
is on a GLP one inhibitor. Again like the ozembic
will go vimunjara. There are many in this class. Now,
(20:47):
I think that there are a number of different things
that patients can do, including taking dietary supplements that can
help them preserve their muscle as they're taking these GLP
one inhibitors. So out of all the supplements, you know,
so okay, first, let's say supplements is one part of
the equation as an integrated pharmacist. I also think, you know,
(21:08):
we touched on this already, but the importance of movement
of strength training or some sort of you know, light
aerobic exercise so you know, walking, walking the dog, and
those sorts of things so important. So it's really this
like multifaceted picture of all these different things. Nutrition is
also extremely important, and that's kind of where supplements play
(21:30):
a role. Is you know, maybe you know, people are
trying to eat healthy, they're trying to up their movement,
they're trying to sleep well. But dietary supplements can really
fit that white space of okay, they're trying all of
these things, but how else.
Speaker 2 (21:44):
We're running out of time? Do you have have recommendations
for us?
Speaker 1 (21:48):
Yes?
Speaker 5 (21:48):
I do.
Speaker 2 (21:49):
Yeah.
Speaker 3 (21:49):
So so the top four I would say for supplements
are omega three fatty acids. A lot of people are already
taking those. They help to reduce muscle inflammation and support
protein synthesis, so we love that. The next would be
branch chain amino acids, also supporting muscle preservation and preventing
muscle breakdown, like lucine for example. The third one is
(22:10):
you know, if you feel like you know, you know,
you're taking a GOLP one inhibitor, you're not getting enough
high quality protein. I always recommend a protein powder, so
that's you know, minimal ingredients. It could be plant based,
it could be way based, but something like that. And
then the fourth one is called bortotropin, and there's a
lot of clinical research to support the use of this
(22:30):
natural compound that is derived from fertilized egg yolk, so
it's raw fertilized egg yolk, and in clinical studies it
showed that it boosted muscle protein synthesis by up to
eighteen percent in adults that were not exercising. And so
for you know, people who are taking GOLP one inhibitors,
(22:51):
they're very busy, they have you know a lot of
different things and responsibilities on their plate. This could be
a great fit for them. And currently the product is
marketed as myos MD, and so MYOSMD is actually only
available through your healthcare provider, so if you are interested,
you can get it through a healthcare provider recommendation. And
(23:12):
there are so many studies. It's why I actually join
the scientific advisory board at the companies because I realized,
you know, there's so many supplements out there, but what
I always look for is where is the research to
support their use?
Speaker 1 (23:25):
What about somebody who doesn't take a GOLP one inhibitor
who wants to build muscle mass.
Speaker 2 (23:32):
Would this work?
Speaker 3 (23:34):
Yes, SUPPORTO troven would be a great fit for them
as well, because in the research that we've done, the
majority of the studies are actually in patients that are
not taking GLP one inhibitors, and so we're able to
see the demonstrated difference in placebo controlled clinical trials that
patients taking this supplement have been able to increase muscle
(23:57):
protein synthesis and increase their muscle girth as well, which
is really incredible.
Speaker 2 (24:04):
Well, my biceps will get bigger.
Speaker 3 (24:07):
That so, especially if you use MYOSMD in coordination with
improving your nutritional health. So thinking about you know how
to up your up the right macros with high quality protein,
healthy fats, healthy carves, because carves are not the enemy,
even though people love to say that, but healthy carves
we absolutely need. So I think as a part of
(24:28):
a balanced, comprehensive regimen, MYOSMD could be a great fit
for people whether or not they're taking GLP ones.
Speaker 2 (24:36):
In particular, you're at a time doctor, would you come back?
Speaker 3 (24:40):
Yes, I would love to come back. I can talk
about this, but I can talk about anything else from
an integrative type of muscle health and longevity perspective.
Speaker 1 (24:47):
I love it.
Speaker 2 (24:48):
Hey, thank you very much. Our guests in Doctor Swampy
and the Integrative.
Speaker 1 (24:53):
Pharmacist, I'm Mark Allen along at the Insane Daryl Wayne,
Don't go Away.
Speaker 2 (24:57):
More coming up as Late Night Help continues
This is Late Night Health. This is the radio show
that cares about the most important part of.
Speaker 2 (00:15):
Your life, your health.
Speaker 1 (00:17):
During the next hour, the Insane Daryl Wayne and I
yet don't ask it he is He and I are
going to take a look at some things that touch
each and every one of us. During the second part
of our show, we're going to take a look at
a new company that was founded by professors from Harvard
(00:41):
to take a look at supplements and test their effectiveness.
And so that's happening in about a half hour from now.
Right now, we're going to go to New York. I
believe we're going to New York or New Jersey, either
one of those places, and we're going to be speaking
with doctor Swa and doctor Swathy Buranasi DS. I think
(01:06):
I got that pretty close, and we're going to be
talking about trading pounds for health problems. Doctor Swanthy, Welcome
to Late Night Health.
Speaker 3 (01:14):
Thank you so much for having me our pleasure.
Speaker 2 (01:18):
So Americans are fat and overweight, There's just no doubt
about it.
Speaker 1 (01:26):
I recently lost twelve pounds and I'm very happy with that,
but another fifteen would be nice. Is it hard to
lose weight in general?
Speaker 3 (01:38):
It is hard to lose weight, and a lot of
that honestly comes down to the food system itself and
what sorts of foods are readily available, and also what
sorts of foods are easily accessible. So I mean readily available,
easy to grab in the grocery store, but I also
mean readily available like the oftentimes foods that are less
(01:59):
expensive are the ones that are not so great for us.
So those two pairing together just can make it very
difficult for the average American to lose weight.
Speaker 1 (02:11):
Food is medicine, and this is a fairly common concept
in the last ten years or so. Would you agree
with that, then, that food is medicine.
Speaker 3 (02:24):
I would agree that food should be viewed as medicine,
as you know, it can have medicinal value. Of course,
it you know, can taste delicious as well, so it's
not just something that we can use for our health.
It's also something that we can enjoy. But I think
that the average American now is starting to think, Okay,
what I'm putting in my body three times a day,
(02:45):
maybe even more often with snacks and beverages really is
impacting my mood and the way that I look and
feel about myself.
Speaker 1 (02:54):
Soft drinks come to mind, and kids, I remember, you know,
as a kid, Coca cola was a treat.
Speaker 2 (03:04):
It wasn't a daily experience, right, Is that still okay?
Once in a.
Speaker 1 (03:09):
While, you have a coke, a pepsi, if you prefer
orange soda, whatever it might be, is that okay? I mean,
I know they're loaded with with the terrible, terrible sugars,
but is it okay once in a while.
Speaker 3 (03:27):
So I always say moderation is best because let's say,
you know, especially when I used to work with patients
one on one, if patients absolutely loved their diet coke,
or they loved their orange soda or you know, fill
in the blank with you know that their you know,
pop or soda of choice. I always said, you know,
I'm not asking you to completely remove it from your diet,
(03:50):
but instead of drinking it every day, let's first start
with once a week, and then let's maybe see if
we can cut down to twice a month or even
once a month. So I think if your body is
not as used to it, your body doesn't crave it
as much. So it's more of that tapering phenomenon rather
than you know, cutting it off and then people crave it,
and then they go back to it, and sometimes they
(04:11):
even they even consumer or something more right. So it's
more about moderation. I don't want people to cut out
things that give them happiness, but at the same time,
we do need to recognize that consuming those things regularly
is really not the best for our health.
Speaker 1 (04:29):
As a As a doctor of pharmacy, you're known as
the integrated pharmacist. What is a food that you know
is not healthy for you, that you crave you love X?
What is X for swathy?
Speaker 3 (04:50):
For me, it has to be some sort of almond
croissant or pistachio croissant, something like that, where you know
it's filled with butter, but at the end of the day,
you know it something I let myself eat, Like monthly,
there's a really good croissant place around the street, and
you know, every month or so, I'm like, oh, the
month is almost suberg Did I have my croissant? So
it's it's not something that I'm cutting out completely, but
(05:14):
definitely something I look forward to and have in moderation.
Speaker 2 (05:17):
Do you have kids? No?
Speaker 3 (05:19):
I don't.
Speaker 1 (05:20):
No, you don't. Well, you can always adopt me with kids,
you know, especially kid number two. Kid number one, you know,
you drop something on the floor and you throw it away.
Kid number two, there's a ten second rule. Okay, you
can eat it. It's only ten seconds. I know the
(05:41):
dog just licked the floor.
Speaker 2 (05:42):
It's okay.
Speaker 1 (05:43):
My point is that should we be teaching our kids
proper eating habits so that they don't need to lose
weight when they're adults.
Speaker 3 (06:01):
I would say yes. And I think that is because
you know, first and foremost kids are going to learn
from their parents, and it's behaviors. It's you know, and
behaviors could be you know, eating behavior, but it also
could be you know, behavior pertaining to movement or mindfulness
or you know, the way that we approach problems. So
I think that's where it all starts and that's the
(06:22):
root of it. But at the end of the day,
you know, the kids are going to make their own
decisions once they leave the house and head to college
or technical school or work wherever they decide to go.
So I think instilling some of those principles early is
the best that parents can do.
Speaker 1 (06:37):
Teenage obesity is also on a ride on the rise,
and I think part of that, to me is because
they don't. They're not as active as I was as
a kid. Not that I'm active now, but when I
was a kid, I'd ride my bike all over the place, right,
we played in the street.
Speaker 2 (06:56):
Kids don't do that as much.
Speaker 3 (06:58):
It's true that they don't, and that's because of the
prevalence of screens. Everyone has, you know, at least what
is the stat like two to four screens per human
or something in the US as the average. So you know,
people are using not only their phones, they have laptops,
they have iPads, they have kindles, you know, all these
things that you know, don't really require any movement to use.
(07:19):
And so I think now they've grown up with the
you know, iPhones in their hands and looking at iPads
starting age too, and so they don't really see the
value in it, simply because it's not the way the
culture is molded right now.
Speaker 1 (07:33):
The we're coming up on the holidays and we are
going to start seeing during the holidays several things. We're
going to be seeing ads for all kinds of foods, chocolate, wine,
perfume that has absolutely nothing to do with our conversation,
but the ads for perfumes will also permeate the airwaves permeate.
Speaker 2 (07:56):
In their nevermind.
Speaker 1 (08:01):
And also we'll start seeing ads for join this gym
only nineteen dollars a month or a dollar to get
in whatever.
Speaker 2 (08:11):
And I know that a lot.
Speaker 1 (08:14):
Of people join the gym make a promise to themselves
how important is it to use that gym membership.
Speaker 3 (08:25):
So the thing is, it's not really about the gym
membership itself. It's more of how can we all find
movement that brings us joy. I think for some people
that is the gym, maybe that's the treadmill, it's lifting weights,
working with a trainer. But for others, especially a lot
of patients that are interested in the GLP one inhibitors
that will talk about they are patients that are either
(08:48):
already overweight or obese, and maybe they're not used to
as much activity. So maybe for them a gym membership
is not going to be as valuable, and instead, for
them it's taking a walk around the block, taking their
dog on a walk, you know, walking to you know,
grab the mail, like those sorts of things, just starting small,
because as I was saying with moderation with food, it's
(09:11):
it's not about changing your whole lifestyle overnight. And so
how can we start small and find something that you know,
our patients like or that people like, and then from
there we can grow and add things. But what I
don't want is people to all of a sudden think
that they need to be doing sixty minute you know,
high intensity interval training, you know, six times a week
(09:34):
or something like that.
Speaker 1 (09:35):
Do you do that kind of high intensity workouts yourself?
Speaker 3 (09:40):
So I don't do high intensity, but I do low intensity.
I really like reformer plates, so I do that. And
then I love long walk, So even if the weather's
not great, put on the scarf, put on the boots,
and I love going on a long walk and catching
up on a podcast or calling.
Speaker 1 (09:55):
My mom, gotcha? And I love walking in Manhattan. I
don't walk as much here in southern California as I
probably should. Our guest is doctor Swathy. She's an integrated pharmacist.
We're going to take some time out. When we come back.
I want to talk about some of the.
Speaker 2 (10:15):
New drugs that are available.
Speaker 1 (10:21):
Some of them are quite expensive. In fact, I think
most of them are quite expensive, and find out if
one they work, two if they're safe, and three if
there are alternatives to help people lose fifteen to twenty
even fifty pounds, so that'll be coming up.
Speaker 2 (10:41):
By the way.
Speaker 1 (10:42):
You can visit us at Latenighthealth dot com. Latenighthealth dot com.
You'll see pretty pictures.
Speaker 2 (10:49):
Of Darryl and me and even our guests like doctor Swathy.
Don't go away. As Late Night Health continues.
Speaker 4 (11:06):
Late Night Help is proud of our partnership with the EBC,
the Evolutionary Business Council. Check them out at Ebcouoncil dot com.
Speaker 5 (11:16):
You're listening to Late Night Help with Mark Allen. The
show continues in a moment.
Speaker 1 (11:25):
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If you're listening to Late Night Health right now, you're
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Speaker 6 (12:31):
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Speaker 5 (12:31):
I'm Darryl Wayne, producer of Late Night Health, inviting you
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(13:15):
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Speaker 1 (13:55):
It's time to tackle a tough topic, one that affects
us all. We're talking talking about sexism in the workplace.
The award winning Identifying the Elephant in the Room series
is back and ready to tackle some complicated communications issues
again this spring we're focusing on critical communication strategies in
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Hear from professionals in the natural products industry who have
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(14:37):
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Speaker 1 (14:55):
Late Night Health continues. I'm Mark Allen along with the
insane darrow Way. Our guest is doctor Swathy the Rahnessy Dias.
Did I blew that one? Let's try it again. Pronounce
your middle you're part of your last.
Speaker 3 (15:16):
Name for us, So yes, it's on doctor Swathy Varanasidias.
Speaker 2 (15:20):
That's easier said than done.
Speaker 1 (15:22):
All right, let's talk about what we said before the break,
and that is, you know, there's some new drugs that
really apparently work and you can drop you know, fifty
pounds or more safe quickly?
Speaker 2 (15:39):
Are these drugs safe?
Speaker 3 (15:44):
So that's the big question, and I think that's what's
getting lost in translation with the discussion of this new
class of drugs. And I see that they're news and
they've been FDA approved. They're called GLP one inhibitors, or
the longer term for that is glucle gone like peptide
one inhibitors. So the way that they work in the
body is that they increase insulin secretion, they reduce glucagon secretion,
(16:09):
and that results in lowering blood sugar levels. And initially
they were researched and discovered for their use in type
two diabetes, and that's how they became popular. Now they're realizing,
oh wow, actually patients who are taking these medications lose
a significant amount of weight, up to fifteen percent of
(16:29):
their weight for some patients, and so they're realizing that
there's opportunities to use this medication and other contexts. So
a lot of people are looking at it as a
quick fix, as a magic bullet, and I think that's
one of my concerns as an integrated pharmacist with the
use of this medication is that you know, everyone thinks, oh,
(16:50):
I can use it and it's the right fit for everyone,
which I also don't agree with. And that also we
can use it all of a sudden lose this weight
and then not have side effects.
Speaker 2 (17:01):
But there are side effects.
Speaker 3 (17:03):
Yes, exactly. So I would say there are four major
red flags associated with these GLP one inhibitors. The first
one is GI issues, So this is gastrointestinal issues stomach
related issues. This could be nausea, vomiting, constipation, and issues
with the stomach not emptying properly, which could lead to
(17:25):
other chronic issues like you know, gastroparesis for example. The
second one is accelerated muscle loss. So this is the
one that I don't see anyone else talking about yet,
and I'm sure it'll be popular soon, but at least
for now. You know, when people are losing weight on
these medications, you know, people are losing fat, but they're
(17:45):
also losing muscle, and so that is something of importance,
especially as we're all aging and we need to figure out,
you know, how we are going to preserve this muscle
that really lends itself to longevity and age powerfully. So
those two are very important. The other two is the
off label misuse so this is you know, patients who
(18:07):
are not technically eligible for the drug in terms of
the way it has been FDA approved. So there's you know,
in this class, it's ozembig, we go V Manjarro. There
are a lot of different medications that are in this class.
Speaker 1 (18:22):
But and this is I think the overariuses or the
misuse is the person may not may be overweight but
not have diabetes so exactly.
Speaker 3 (18:34):
So actually, like for exam, for example, we go V
is FDA approved for patients that are overweight but then
have some sort of comorbid condition, so they have some
sort of other chronic disease state that could make their
type two diabetes worse. Or the patient has a BMI
of over thirty, which is classified as obese. And so
(18:54):
for those patients, those are the patients in which it's
been researched, it's been FDA approved. However, a lot of
patients that are taking it are not falling into those
two categories. And so that's what I mean by off
label misuse is that you know, we actually don't have
the empirical data to say, yes, we should use it
in these patients, but a lot of the data has
(19:15):
been you know, kind of extrapolated from these other patient populations,
and then patients who are maybe not in need of
it so to speak, are using it. And then the
fourth red flag to just round out the top four
is mental health side effects. So patients have reported you know,
changes in mood swings and also you know, the lack
(19:37):
of reward or excitement when it comes to eating food.
Speaker 1 (19:42):
Wow, are there supplements that will help people lose weight
drop weight.
Speaker 2 (19:52):
That don't have side effects?
Speaker 1 (19:54):
Now, everything has side effects, we know that, but at
least they'll be there, they're mild side effects.
Speaker 3 (20:04):
So while there are supplements that are on the market
right now that are being marketed as GLP one alternatives
or substitutes or natural versions, and this, that and the other.
You know, at the end of the day, I'm a pharmacist,
so I'm always looking for where is your data, where
is your research to support the use of these And honestly,
(20:24):
do you have head to head studies that demonstrate that
this supplement is as effective or you know, maybe just
a little bit less effective or more effective than this
class of medication. So at this time, I have not
found a supplement that does that. However, if a patient
is on a GLP one inhibitor. Again like the ozembic
will go vimunjara. There are many in this class. Now,
(20:47):
I think that there are a number of different things
that patients can do, including taking dietary supplements that can
help them preserve their muscle as they're taking these GLP
one inhibitors. So out of all the supplements, you know,
so okay, first, let's say supplements is one part of
the equation as an integrated pharmacist. I also think, you know,
(21:08):
we touched on this already, but the importance of movement
of strength training or some sort of you know, light
aerobic exercise so you know, walking, walking the dog, and
those sorts of things so important. So it's really this
like multifaceted picture of all these different things. Nutrition is
also extremely important, and that's kind of where supplements play
(21:30):
a role. Is you know, maybe you know, people are
trying to eat healthy, they're trying to up their movement,
they're trying to sleep well. But dietary supplements can really
fit that white space of okay, they're trying all of
these things, but how else.
Speaker 2 (21:44):
We're running out of time? Do you have have recommendations
for us?
Speaker 1 (21:48):
Yes?
Speaker 5 (21:48):
I do.
Speaker 2 (21:49):
Yeah.
Speaker 3 (21:49):
So so the top four I would say for supplements
are omega three fatty acids. A lot of people are already
taking those. They help to reduce muscle inflammation and support
protein synthesis, so we love that. The next would be
branch chain amino acids, also supporting muscle preservation and preventing
muscle breakdown, like lucine for example. The third one is
(22:10):
you know, if you feel like you know, you know,
you're taking a GOLP one inhibitor, you're not getting enough
high quality protein. I always recommend a protein powder, so
that's you know, minimal ingredients. It could be plant based,
it could be way based, but something like that. And
then the fourth one is called bortotropin, and there's a
lot of clinical research to support the use of this
(22:30):
natural compound that is derived from fertilized egg yolk, so
it's raw fertilized egg yolk, and in clinical studies it
showed that it boosted muscle protein synthesis by up to
eighteen percent in adults that were not exercising. And so
for you know, people who are taking GOLP one inhibitors,
(22:51):
they're very busy, they have you know a lot of
different things and responsibilities on their plate. This could be
a great fit for them. And currently the product is
marketed as myos MD, and so MYOSMD is actually only
available through your healthcare provider, so if you are interested,
you can get it through a healthcare provider recommendation. And
(23:12):
there are so many studies. It's why I actually join
the scientific advisory board at the companies because I realized,
you know, there's so many supplements out there, but what
I always look for is where is the research to
support their use?
Speaker 1 (23:25):
What about somebody who doesn't take a GOLP one inhibitor
who wants to build muscle mass.
Speaker 2 (23:32):
Would this work?
Speaker 3 (23:34):
Yes, SUPPORTO troven would be a great fit for them
as well, because in the research that we've done, the
majority of the studies are actually in patients that are
not taking GLP one inhibitors, and so we're able to
see the demonstrated difference in placebo controlled clinical trials that
patients taking this supplement have been able to increase muscle
(23:57):
protein synthesis and increase their muscle girth as well, which
is really incredible.
Speaker 2 (24:04):
Well, my biceps will get bigger.
Speaker 3 (24:07):
That so, especially if you use MYOSMD in coordination with
improving your nutritional health. So thinking about you know how
to up your up the right macros with high quality protein,
healthy fats, healthy carves, because carves are not the enemy,
even though people love to say that, but healthy carves
we absolutely need. So I think as a part of
(24:28):
a balanced, comprehensive regimen, MYOSMD could be a great fit
for people whether or not they're taking GLP ones.
Speaker 2 (24:36):
In particular, you're at a time doctor, would you come back?
Speaker 3 (24:40):
Yes, I would love to come back. I can talk
about this, but I can talk about anything else from
an integrative type of muscle health and longevity perspective.
Speaker 1 (24:47):
I love it.
Speaker 2 (24:48):
Hey, thank you very much. Our guests in Doctor Swampy
and the Integrative.
Speaker 1 (24:53):
Pharmacist, I'm Mark Allen along at the Insane Daryl Wayne,
Don't go Away.
Speaker 2 (24:57):
More coming up as Late Night Help continues
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