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November 20, 2025 30 mins

Playoff implications loom large as the San Francisco 49ers and Carolina Panthers clash on Monday Night Football. With Brock Purdy returning at quarterback for the Niners and Bryce Young coming off a record-setting 448-yard passing game, both teams look to solidify their NFC playoff hopes. Can Young build on his momentum, or will Purdy and Christian McCaffrey guide the 49ers to victory despite multiple injuries on defense?

 

Brian Peacock and Julian Council break down the Panthers’ resurgent ground attack with Rico Dowdle, the impact of key defensive injuries—including the loss of Nick Bosa and Fred Warner for San Francisco—and the challenge both teams face in generating a pass rush. With Christian McCaffrey facing his former team for the first time and both squads battling inconsistent play, which side gains the edge in this pivotal NFC matchup?

 

San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker.

 

Follow & Subscribe on all Podcast platforms…

🎧 https://link.chtbl.com/LO49ers?sid=YouTube

 

Locked On NFL League-Wide: Every Team, Fantasy, Draft & More

🎧 https://linktr.ee/LockedOnNFL

 

Follow Brian Peacock and Eric Crocker on Twitter, where they’ll be sharing the latest news about the Niners and talking with fans.

Twitter: twitter.com/BDPeacock, twitter.com/eric_crocker

 

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