Episode Transcript
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Speaker 1 (00:10):
Well, welcome to episode eighty two of Sperbs Herbs. Today
we're gonna be talking about song chert tongue or scallion
and prepared solving decoction. So, without further ado, let's get
into today's episode. And today we will be looking at
another as I just mentioned, Chinese herbal formula. In fact,
(00:31):
we're going to look at probably the first formula most
of us learn in school, song chuir tongue or scallion
and prepared soyving decoction. This is a mild formula for
releasing the exterior I may easily maybe easily created most
kitchens without any major herbal inventory. I'm gonna tell you
about that as we go along. As always, we will
(00:53):
do our deep dive into this herb formula and look
at its traditional uses and its preparation interactions and and
as usual and interactions. There's some interesting interactions here, so
we're going to be getting into those as well, and
as usual, we will be adding something a little different.
We will be looking at pharmacognacy and several glycosides which
(01:16):
are under the heading of pharmacognocy. We're going to talk
about what those are. It is going to be another
interesting trek into the exciting universe of herbs. Please join
us Before we get going, I just wanted to let
you know. You know, I've been teaching for quite a
while now on a wide variety of topics. If you
(01:37):
like this podcast, want to explore many more of my
courses there are. They are available at www dot Integrative
Medicinecouncil dot org. That's Integrative Medicine Council Council dot org
and include a ton of different topics, including my Drug
Herb series looking at drugs and how they interact with
herbs and vice versa, several ethics and saale courses, Chinese
(02:01):
medical research, several treatment of condition courses such as arthritis,
new can backpain, COVID depression, and anxiety. One of my
favorite courses the Chinese Herbal First Aid Kit, and they
are all at a reasonable cost just period. But you
can also now get an additional twenty percent off with
(02:25):
the code SH twenty off. That's SHS and sperbs herbs
two zero o ff all lower case, so SH two
zerof F twenty percent off are already low prices. So
let's talk about pharma cognicy. I just finished presenting a
class on pharmacognizy for my integrative nutrition series. I thought
(02:47):
parts of it would be perfect for sperbs, herbs and
it's little something different. So here is a little introduction
to pharmacognozy and then a discussion of some plant constituents.
So we're gonna start with the term pharmacogacy. It was
first coined in eighteen eleven by Johann Adam Schmidt, German
who lived from seventeen fifty nine to eighteen nine, and
(03:11):
it was first found in my German. Is much worse
than most of my languages. There are book they're materia medica.
That's as close as I can get to that. It
is derived from Greek pharmicon or a drug, and gignosco
to acquire knowledge of, so it's basically its acquiring knowledge
(03:34):
of drugs. There is the American Society of Pharmacogncy and
they describe what pharmacogacy is in its areas of study.
Learn't just talk about is more than anything else. Pharmacognoscy
is the study of natural product molecules, typically secondary metabolites.
We'll talk about what that is in just a second,
(03:55):
that are useful for their medicinal, ecological gustatory or other
functional properties. So that's a tight definition of pharmacontocin, but
it's a broad thing to study, so let's talk about
those secondary. So primary metabolites necessary for life include fats, carbohydrates,
(04:17):
and menium, acids and proteins, all of which are can
be supplied by plants. There are also lots of secondary
metabolites which may not play a direct impact on life
but may be important for health. Vitamines which can fall
into this category, and vinerals are also present in plants
and are considered secondary metabolites for the most part. And
(04:38):
then there are at least one million other compounds in plants,
and that is where we start to look for how
they may affect our bodies and our health. So that's
a lot of different compounds in these plants. We're just
starting to learn about them. Over the evolution of plants,
many different classes of chemicals have been produced by plants
(05:01):
for various reasons, including protection of UV damage, ultra violet damage,
repelling feeders, defense against microbes, and to aid reproduction and pollination.
And many of these chemicals have beneficial effects on humans.
We get in I have this great course that I honestly,
(05:22):
it's not one of my more my more commonly observed courses.
It's called why not how do Herbs Work? And it's offended.
It's it's my favorite, absolute favorite course. It gets into
philosophy and uh ethics and not ethics but but pharmacognocy
(05:44):
and and and just evolution and all kinds of really
cool concepts. Fantastic course, and everyone who takes us to
this was very different than any other course I've ever taken.
I loved it. So that's why, you know, just not
a lot of people have watched it, but those who
haven't just adored it. And I adore it. It's fantastic,
(06:04):
and it kind of talks a little bit about these
why would plants have any chemicals that would be useful
to humans at all? And it gets into that as well,
So it's fascinating. That's a great course as well. So today, however,
we will look at some glycosides, which are one of
these categories of phytochemicals phito meaning plants, so plant chemicals
(06:26):
and how they may be helpful to humans. Basically, glycosides
are made up of two chemicals. One chemical is known
as an a glycone, so a meaning not gli meaning
glucose or sugar, glant cone just meaning a chemical that
is sugar, so and a glycone means there is no
(06:49):
sugar molecule. And the second chemical that is part of
a glycoside is a glycone or a saccharide, which are
sugar spased, so most often a monosaccharide that means one sugar. Remember,
sugars can can kind of snap together and disaccharides and
(07:11):
polysaccharides and things like that, but monosccharides are one sugar
commonly is probably the most common sugar round is glucose,
though there are other sugars can be this glycon or
sacharide that is part of the glycoside, and those other
sugars include ramnose, fructose, rabinose, and xylose. So there you go.
(07:32):
Glycoside basically means there is a there's a sugar portion
to it. They are linked together. So these two different chemicals,
the egg glycone and the glycone are linked together by
a glycosidic bond which can be linked through specific elements
O glycosides. The most abundant plant glycoside is through an
(07:54):
oxygen glycosidic bond C glycosides are linked through a carbon bond,
S glycosides are linked by a sulfur bond, and N
glycosides are linked through a nitrogen bond. So there are
several different subtypes of glycosides, so we're going to talk
about a few of them, not all of them, but
(08:16):
probably the more important ones. So the first ones we're
going to talk about are phenolic glycosides. So phenols are
a benzene ring with at least one hydroxyl group. Okay,
so that's kind of technical chemistry, But a benzene ring
is basically six carbons in a ring, and between those
six carbons they share three double bonds, and technically it
(08:40):
gets a little in the chemistry, it gets a little
bit weird. You'll see if you can see this here,
there's a little tring and there's like three lines in
addition to the lines connecting the carbons, and that indicates
the double bonds. But sometimes you'll see this with a
circle rather than three lines, because they actually share those bonds.
So it's like, you know, it's not like three double bonds,
(09:01):
it's more like six one and a half bonds might
be a better way, six half one and a half ons. Yeah,
so that would be about right. So that's what a
benzene ring is, and then there's a hydroxyl group with
which is an oxygen and a hydro hydrogen, and that's
coming off of this benzon ring, and that's what's known
as a phenol. So common plant phenols are catachol, guyacol, hydroquinone,
(09:28):
and fluoral glucanol. These phenolic glycosides, also known as phgs,
consists of a phenyl group attached to a glycone, so
that's the sugar portion, So that's where we get the glycoside.
So there's a phenol and a glycone. Phgs are widely
distributed in plants and includes selicin, populin, are buttant, conifferent
(09:51):
gluc of vanillin, as well as glycosides of phenolic acids
p hydroxy benzoic acid. Not going to add the acids
to hollidays, proto cateacuic acid, vanilic syringic salicylic acid. If
you're familiar with salicilic acid, is cetyl salicilic acid. That's
aspirin O proto ctcuic acid. Gallic allergic ellagic l E
(10:19):
L A g I see ellergic and rosmarnic, so that's
from rosemary as well as other plants. These those are
all acids. The bioactivity of various phenolic glycosides can vary
quite a bit, but can include anti inflammatory, anti poetic.
In other words, they lower temperatures and fevers, anti rheumatic,
(10:41):
anti microbial, and antioxidant. Not a lot of adverse effects
have been reported other than some topical skin effects for
some of them and some gasin testinal effects for others. Basically,
anything that you can take internally can cause some GI effects.
Another type of glycosides are the kumerin and chromone glycosides.
(11:04):
Now these may sound like two different glycosides, and they
are technically, but we're going to see that cumberin and
chromone are super close together as far as chemicals are concerned.
So cumberines consist of a pyne ring attached to a
benzene ring, as do chromone, so the chromones, so they
are exactly the same in that. However, the oxygens are
located in different positions in these chemicals, So the only
(11:27):
difference between a kumarin and a chromone is the oxygen
is in a different position. So we have that phenol
it's not a phenol ring and it's benzin ring. So
we have those six carbon ring with three double bonds,
and then we have that attached to a pyne ring,
which is basically a five carbon ring with one double
bond and an oxygen in there. So there's five carbons
(11:47):
in anoxygen, so it still has a hexagonal sort of
look to it, but it has an oxygen in there.
And both of these have an oxygen, a double bonded
oxygen coming off of the pyne ring as well. Crimerins
have several potential health benefits including anti tumor, anti hiv, antibacterial,
anti coagulant, central nervous system stimulate, anti inflammatory, and photochemotherapy.
(12:12):
In other words, it can help with chemotai light therapy,
chemotherapy for specific type of anti cancer, and anti hyperlipidemic,
so it can actually lower cholesterol in lipids. Two new
chromone glycosides five hydroxy two six eight trimethyl chromone seven
(12:34):
O B d glucopy peranocide. That's the old technical name.
The short name for this is uncinocide A. And then
the other chromoglycoside that we're talking about is five acetyl
oxial two six eight trimethyl chromone seven O B D
glucopyre perinoside or uncinocide B. So they're very as you
(12:56):
can tell, they're very close, which are isolated from the
Chinese herb Slaginella on sonata spring, which is suiyunsao, which
is not one of our more common Chinese herbs. But
both of these showed potent antiviral activities against ruspiratory sensicial
virus and moderate antibacteria anti viral activities against para influenza
(13:19):
type three virus. That's why those are relatively well known.
And this came from what I'm using as one of
our main parmacognity text texts here, and I had been
using the older version of it, but a new version
just came out this year twenty twenty four, and so
that's the version that includes So when they say new,
they mean new. So some cumerins it cause mild nausea, diarrhea, photosensitivity,
(13:44):
and enlarge enough quantities of patotoxicity. In other words, it
can cause liver problems. Photosensitivity means light issues is usually
like you're more sensitive to light skin wise, like you
get sunburn and things along those lines. Chinese rbs that
contain these compounds include don gue which is one of
our most common Angelica sinensis, one of our more common herbs, douay,
(14:08):
and the aforementioned sway yunsal. So that's stuff that's cumerin
and chromone glycosides. Let's briefly talk about flabinoid glycosides. Flavonids
are polyphenolic compounds, so we know what a phenol is.
It's that six group with an hydroxyl group conover, so
(14:29):
these are polyphenolics, so there's multiples of them put together.
And the flabinoids include flavones, fabinol, chalcone, flavanone, oorone, flabon
of phlamononol, isoflavone, and anthocyanidine. And then we have a
whole other category called bioflabinoids, which are where two flabinoids
(14:51):
are linked together. They may have beneficial effects such as
being vasodilatory so they open up our vascually, anti inflammatory,
anti bacterial, anti viral, anti allergic, sidotoxic, so that means
cell killing. But really what that is talking about is
anti cancer and anti tumor, so both of those would
(15:14):
be considered approaches for treating cancer. Overall, they appear to
be quite safe with badala mccrath and Clement. That's that
textbook I was talking about earlier, saying high doses of
flabinoids intake do not appear to cause serious side effects,
and flabinoids are getting a lot of preslately, you know,
saying hey, get your flabinoids. Here's a pill that will
(15:34):
give your flabinoids. So that's there's definitely got some mainstream
sort of credit around it. Chinese serves that contain flabinoid glycosides,
there's a lot of them, but here these are the
ones mentioned in this textbook. Those include Putao bi En
Shoe Huang Qin goose will be Goo Swilli Boo Hong Hua,
(15:57):
lou do Ye Guigan, and Guangyelean chaw So guanielan chow
is is Saint John's Ward or hypericum if in the
British areas. So that was the flavonoid glycosides. Let's mention
a couple more anthra quin glycosides, an through quinone glycosides.
(16:22):
The anthro quinone structure is one of three benzene rings.
So there you go, just three benzin rings put together.
And I have a little picture here that has a
couple double bonded oxygens coming off of the middle benzing ring.
Several plants containing anthra quinine glycosides are laxative in nature.
High doses and long term use can lead to excessive
loss of fluids and electrolytes, and Chinese nerves that contain
(16:45):
these compounds included how Huang Jiao lu how wang Jiao
lu lu Hui, which is one of the species types
of alo lu Hui da Huang, one of our major
herbs for stools in fanche Folum sena very commonly used
herb for a laxative herb as well, both in Chinese
(17:06):
and in Western medicine, Western neurbal medicine, and our final
glycoside that we're going to talk about today are the
siponin glycosides. The word siponin is derived from the Latin
word sappo, meaning soap. Suponin's form stable soap like amphophilic structure.
So an amphophilic structure means one side of it is
(17:29):
hydrophilic it likes water, and the other side is hydrophobic
it doesn't like water. And it's fat soluble, and so
they both they have both fat soluble and water soluble aspects.
They may have a diverse range of effects including cytotoxic
and anti tumor, anti viral, and padoprotective, so it protects
the liver, neuroprotective, it protects the nerves, anti hyperlipidemic, hyper lipidemic,
(17:54):
It lowers fats and cholesterols in the blood, anti inflammatory,
and adaptogenic, so that's an interesting herbal term. Adaptogenic. It
means it can do a lot of different things. Adverse
effects can include toxicity at high doses in long term use,
as well as gastrointestinal effects. Chinese herbs with these compounds
(18:17):
include gonzole licorice, one of probably the most commonly used
Chinese herb Renschen. That's ginsing very well known Chinese herb
see wu ja. Another pretty useful herb not as well
known as gonzur Renchen that's a canthopanthus. And then huluba
is another one not as commonly used. Well, that was
(18:40):
a brief introduction introduction into pharmacognitcy and one group you know,
phyto phytochemicals glycosides. If you want to know more about pharmacogacy,
check out Course ten of my Integrative nutrition series. And
with that little something different, let's get into today's formula.
(19:01):
Today we're going to be talking about song. Chur tongue
is simply the short names of its two ingredients, scalon
and prepared soybeans. So that's what it literally means is
scalon and prepared soid being decoction. Tongue means decoction. Other
names include scallon whites and prepared soybean decoction, So that
song by chur tongu by meaning white. This formula is
(19:24):
in the subcategory of formulas that release early exter early
stage exterior disorders, under the category of formulas that release
the exterior according to Shide in his team are other
usual formulas. Textbook Chinese Medical Herbal Formulas and Applications Pharmacological
Effects and Clinical Research by Chen and Chen says it
(19:45):
is in the acrid and cold exter releasing formulas subcategory
under the exterior releasing formulas category. So it's interesting it's
not early. They don't have a category of early the
formulas that release early stage exurgis or are they it
into relieves cold and exterior forma Formula says it's an
(20:06):
the acrid and cold exterior releasing formula. So if you
have a cold exterior pathogen attacking you. Then this is
the formula to use, one of the formulas that you
could use. So one of the interesting differences between her
two texts is that Changsha do not actually have this
formula as a separate mainline formula like it is in
(20:28):
shy It at all and Chen and Chen's text is
considered a related formula to the formula chug Chuir Jaygong tongue,
So Chongture is the same formula that we have, but
Jagong is a different herb, and this formula is in
the subcategory of acrid and cold exter releasing formulas includes
the two herbs of our current formula as well as
an additional six herbs, so it's a much bigger formula.
(20:51):
And then they consider this to be a related formula
to that. So let's talk about formulas that releases. Ser
been going over these formulas that released six years so
we've discussed it in a couple episodes at this point,
including an episode fifty eight and I think an earlier
one that we just did a month or two ago.
(21:12):
So this may sound a little familiar, but it's important
to kind of go over these. So they describe the
overall category. Shide and his team describe the overall category
in the following way. When a pathogenic influence first penetrates
the body, it tends to cause the disorder of the exterior.
In this context, the term exterior biaal denotes the superficial
(21:33):
layers of the body composed of comprised of the skin
and muscles. These are perfused by the body's protective chi,
which is fierce and hot in nature, and whose task
it is is to warm and defend against penetration into
the body by external pathogens. Of a pathogenic influence lodges
(21:53):
in this aspect of the body, it not only obstructs
the normal physiological diffusion of chi and fluids there, but
incur urages the body to move more protective chi towards
the exterior in an attempt to push out the invading pathogen.
For this reason, exterior disorders are characterized by fever and chills,
indicating obstruction of normal physiological warming, even as protective young
(22:17):
in the exterior tends towards excess head and body aches
indicating obstruction of chi and fluids in the most young
ie exterior portions of the body and a floating pulse,
indicating the movement of protective young toward the exterior. Since
wind is the vehicle by by which other external pathogenic
influences enter the body via the exterior, it is involved
(22:39):
in most exterior disorders, especially those involving cold and heat. Thus,
it is said that wind is the leader of the
one hundred diseases fung wi by being churred chong. The
symptoms associated with an exterior disorder indicate that the body
is actively trying to overcome obstruction of the she dynamic
(23:00):
by one or more of the six pathogenic influences. Treatment
in Chinese medicine seeks to support these physiological reactions through
strategies that release the pathogenic influence from the exterior JBO.
For this purpose, one deploys light, acrid moving herbs that
unblock obstruction, diffuse the protective chi, and disseminate fluids to
(23:25):
vent pathogenic influence back towards the outside. No other strategy
will prevent the pathogenic influence from penetrating more deeply into
the body. Often, but not always, this results in sweating.
This type of sweating indicates that an obstruction has been
overcome and that the ch influids can once again stream
to the surface of the body, like the flow of
(23:47):
water that breaks through a dam. The sweating may initially
be pronounced, especially if a very acrid and warming formula
is used. However, the profuse sweating should quickly abate as
the body finds its physiological balance. For this reason, releasing
the exterior is often equated with inducing sweating. Yet in
many contexts where formulas to release the exterira are used,
(24:11):
the sweating may hardly be noticeable, or strong path of
logical sweating may evolve into a mild physiological sweat. This
is because the ultimate goal of these fronts is not
to promote sweating, but to unblock and restore order to
the flow of chi and fluids. The term released from
the exterior was first described in chapter five Basic Questions.
(24:33):
This is referring to Wangdhini Jing su Wen, which is
the first existing book and really on medicine, but in
Chinese medicine specifically, and here's a quote from there. From
that chapter five, if a person harbors a pathogen, the
body becomes soaked as the movement or protective chee to
the exterior transforms fluids into sweat. Hence, when the pathogen
(24:56):
is at the level of the skin, use sweating to
dis charge it. The first known text list herbal formulas
that embody this strategy is the early third century work
Discussion of Cold Damage, which provides some of the most
influential formulas in this category, such as the feder decoction
mahlong tongue, sentiment to a decoction guager tongue, and their variants.
(25:21):
Its focus on acrid warming herbs to overcome obstruction from wind, cold,
and damnness dominated medical practice until the genuine dynasties of
the twelfth to fourteenth centuries, so a thousand years. Basically
innovation until then consisted of extending the range of substances
used to promote sweating, rather than seeking new areas of application.
(25:46):
This changed in the twelfth century with Leo Wan Sioux's
focus on heat pathogens, which led to the idea that
heat in the exterior can occur there directly, rather than
being due to constraint caused by cold. Venting such heat
requires the use of acrid cooling substances, which do not
necessarily promote noticeable sweating. The treatment strategies and formulas composed
(26:08):
by seventeenth and eighteenth century physicians like Yeten Sure and
Wujoutang are associated with the warm pathogen current are most
emblematic of this approach. Other innovations stemming from the genuine
Area era are the combination of exterior venting with tonify
nerves to treat exterior excess combined with deficiency of chie
(26:30):
blood or fluids in the interior, and the use of
herbs to dispel pathogens from specific channels and their associated
surface regions. Sweating is the first of the eight methods
of treatment formulated by the eighteenth century physician Chung Guo Pung,
underlying its importance and clinical practice, Yet many practitioners continue
(26:51):
to underrate this method. This is unfortunate because the odds
of preventing the development of a serious condition are always
better when the intervention occurs at the early stage of
an illness. It is best to treat diseases at the
level of the skin and hair. The next best is
to treat them at the level of the muscles and flesh.
The next best is to treat them at the level
(27:12):
of the sinews and vessels. The next best is to
treat them at the level of the six young organs.
The next best is to treat them at the level
of the five yen organs. When treating at the level
of the five yen organs, half the patients die and
the other half survive. And this was a quote from
Basic Questions the chapter five again of the Wangdan Aging
(27:33):
Siu Win that we mentioned earlier. Successful use of the
formulas discussing this chapter will be aided by paying attention
to the following principles. First, accurate diagnosis is essential. If
an interior disorder develops before the exeter has been released,
the practitioner must choose between releasing the exterior first or
(27:55):
treating the exterior and interior simultaneously. Formulas in this chapter
inappropriate for treating disorders solely of the interior expressed rashes
or a dima due to deficiency. Likewise, it is important
to be clear about the precise nature of the pathogenic
influence to be released, as this determines the choice of formula.
(28:16):
One must also be cognizant of the type of sweating
to expect from a particular formula. Second, most of these
formulas should be cooked briefly. They treat acute disorders and
are prepared as decoctions or powders. They contain substances, substances
that are light and volatile in nature, which, if subjected
to too much heat, lose their efficacy. Third, formulas taken
(28:40):
hot after meals will provide the best results. Sweating is
further encouraged by instructing the patient to handle it to
bundle up after taking the medicine, as the wealth of
sweating is not sweating itself, but to assist the function
of the protective chi Only a slight sweat over the
entire body is needed to release the exterior. Excessive sweating
dissipates the she and fluids. Fourth, the formula in dosage
(29:05):
should be adjusted to the individual's constitution, local climate, and season.
For example, a person who sweats easily lives in a
warm climate and contracts an endlist during the spring or
summer requires only mild treatment. On the other hand, a
person who does not sweat easily lives in a cold
climate and contracts an illness in the autumn or winter
requires stronger treatment. So that's a quick rundown of formulas
(29:31):
that release the exterior. Remember there's a subcategory this formula
is in, and that is the formulas that release early
stage exterior disorders. So let's see what SHID has to
say about that. So the Shide at All also describe
the subcategory of formulas that release early stage exterior disorders,
and here's what they say. In the first stage of
(29:52):
an externally contracted disorder, a person will feel as if
the outer layer protection has been stripped off, making them
feel very vulnerablnerable to drafts. This sensation is called aversion
to wind wufong and can be treated by a simple
infusion of alii, fistulosi, bulbous or song bye. That's the
main herb that we're going to be talking about here.
(30:14):
That's green onion. Stronger chills indicate that the condition has
progressed slightly and that it requires one or another of
the formulas discussed in this SAP subcategory. These formulas should
be prescribed for one or two doses only if ineffect
of a stronger formula is needed. So that's the overview
(30:36):
of the formulas that release early stage exterior disorders. So
talking about our formulas today, song chir tongue, what does
it do? Whatever, it's Chinese medical actions. So Shide at
All say this formula unblocks the young protective chi in
the exterior and induces sweating, and because this is related
(30:58):
to say change, I do not have civic actions for
this formula. Usually like to compare the two of them,
but they both have some indications some Chinese medical indications
for this, so Shine in his team say this formula
can be used for mild fever and slight chills without sweating, headache,
stuffy nose, a thin white tongue coating, and a floating pulse.
(31:20):
This is the earliest stage of an externally contracted wind
cold or wind heat disorder. The lungs govern the exterior
as well as the skin and nasal passages. When wind
cold attacks the exterior, wind heat attacks the lungs directly.
The first symptoms are fever and chills, indication that protective
that the protective chie and the pathogenic influencers are struggling
(31:43):
with each other in the exterior. As a consequence, the
protective cheek cannot fulfill its normal function of warming the exterior,
causing chills causing chills. Meanwhile, the constraint of young chi
in the exter it leads to an accumulation of heat
and thus, since this is the earliest stage of the disorder,
(32:05):
all of the signs and symptoms are mild. That's important
concept here. These are mild chen Chen Say song chure,
tongue or skyion. Prepared swiping in decoction treats early onset
of a mild exterior syndrome through diaphriesis, which is a
nice technical term meaning sweating. Clinically, patients may show fever,
(32:26):
a version of cold, absence of perspiration, headache, stuffy or
running nose, and sneezing. So similar to the indications from Shide,
not as verbose. So what is the history of this formula?
So both Shide and his team in Chen Chen say
(32:48):
it sources Joe Holbai Giufang or emergency Formulas to Keep
up One's Sleeve, written by Go Hong. Shide at all
say this book was written in the third century, while
Chen and Chense was written in three forty one, the
middle of the fourth century in CE. And I hate
differences like this, especially when they're they're talking about the
(33:11):
same book. So I did some research, which really didn't
help that much. One STUDI said go home live from
two eighty three to three sixty three CE, while a
PhD dissertation says he lived from two eighty three to
three forty three uh CE. So they got the birth
seems to be the same in these different sources. But
(33:34):
how long he lived is not. One says he lived
to be eighty, another one said he lived to be sixty. Well,
both discussed the Both these papers discussed his writing of
this book. Neither has a specific date as to when
the book was published. Considering it very unlikely it would
have written it by age seventeen, which would have been
the end of the second of the third the second century,
(33:56):
and believing seventeen year olds didn't write books in ancient China,
it is very unlikely this was written in the third century.
So I suspect three forty one CE is the relatively
accurate date of publication. So there we go again. I
don't have the end all be all of exactly when
it was published, but the three forty one seems more
(34:17):
accurate than than sometime during the second century the third century.
So let's talk about the ingredients, which are cool because
there's only two of them, so the first ingredient is
so before we get into green. So let's just talk
a little bit about greens in general, when colder, when
(34:37):
heat in the exture of the body is dispersed with
acrid herbs. A mild condition in its early stages can
be true with light and gentle herbs that induce gentle sweating.
And that's really the tubs that we're talking about today.
First herb is Alii fistilosi bulbous song bai or green onion.
Buy this in almost any supermarket and the US as
(35:00):
three to five stocks or nine to twelve grams. Chen
say it's one handful of three stocks, and it's in
the category of warm acrid herbs that release the exterior,
and its normal functions are it releases the exterior and
induces sweating for externally contracted when cold, especially in the
(35:21):
very early stages, disperses cold and unblocks the young for
either abdominal pain and distension or nasal congestion due to
blockage of young chi by cold, and resolves toxicity and
disperses clumps for sores and abscesses. It's not really used
that often for that context, except for sometimes it might
be you know, kind of ground up and used as
(35:42):
a paste for other herbs as well. I've seen that before.
Alii fistelosi bulbas sung bai is a warm acrid herb
that unblocks the flow of young protective chi in the
exterior and induces sweating. So that's that's from the formula.
You know what they say this does in this formula,
(36:03):
and that brings us to our second ingredient today, Soja
sieman preparadum or dan do chi. It's prepared soybean, so
it's a sowaving product. And the dosage is twelve to
thirty grams according to Shide and his team, and chen
Se only six grams, so it's much smaller dose. And
(36:25):
it is in the formula in the in the category
this herb category of cool acroderbs that release six here.
So the sung bay is in the warm acroaderbs that
release six here. This down do chi is in the
cool acroaderbs that realase six here, which may explain why
it's good for both treating cold wind cold and wind heat.
It is relatively neutral and temperature. It can help both.
(36:46):
Its normal functions are it releases the exterior for both
hot and cold exterior disorders and eliminates irritability. So and
according to shi and what its use is in this formula,
Seemen prepper utum don DECI releases both externally contracted pathogenic
factors from the exterior and constrained young chi in the interior. Together,
(37:10):
both of these herbs gently release the exterior, which is
all that is needed to resolve this pattern. So very
gentle and general. So now that we have the two
ingredients to this, I'm gonna tell you, because it's not
not on any of my sites, I'm gonna tell you
why I love this formula. It's one of those formulas.
So sometimes I'll have a patient call and say, hey,
(37:30):
I think I'm getting cold. Do you have any suggestions?
Not just patients, friends and family and all that, So
I usually have one of the two recommendations for them,
and one of them is to drink peppermint tea peppermint
and fresh ginger tea. So peppermint is that wind is,
you know, acroating and cooling, and ginger is warming and cooling,
(37:53):
and most people have that on hand. So just a
couple of slices of ginger and some peppermint tea that
they may have in the in the cupboard and drink
that and that kind of does without seeing them. I
don't know if it's a win heat when cold, but
that can help quite a bit with that. So that's
one thing that I often will recommend. The other thing
I will recommend is this formula. And in the context
(38:14):
that I recommend this formula, it's not exactly this formula
pretty darn close is. I recommend they go get some
miso soup because miso soup has make sure there's a
scalllion in it, and maybe add a little bit of
scalion in it, but you want it has scallion and
it has Miso is basically prepared soybean. It's a fermented soybean,
(38:36):
and they often have little cubes of dofu in it
tofu in it, so which is also soybean. So that's
basically this formula, ready to go and easy to eat.
So if they don't have that in the house, they
have packets of it you can buy. You know, some
people will have that in the house. Some people have
the ingredients in the house to make it, which I
(38:56):
always do because I love Japanese food. Or you can
just quickly go to a Japanese place and get some
mes soup and what a great little soup and ready
to go for someone's who's having a bit of the
beginnings of a cold and that's basically this formula. That's
not exactly but it's a pretty darn ballparky and it's
(39:17):
one of the first things I will recommend to someone
potentially when they're starting to fill a cold coming on.
So there you go. So commentary. So as usual, Shide
and their team has an excellent commentary about this formula,
and this is what they say. This is a rather
neutral formula that will not dry out or injure the fluids.
(39:40):
It is useful for the treatment of mild exterior conditions,
especially those marked by headache and nasal congestion. Most modern
textbooks prescribe this formula primarily for wind cold externally contracted disorders. However,
typically in such cases the individual will rarely seek attention
until after they can dition is worsened. The formula is
(40:02):
therefore usually prescribed with additional herbs. Yet some practitioners recommended
for treating any kind of pathogenic chi in the exterior. Historically,
it was certainly a very popular formula among leading physicians
associated with the warm pathogen disease current, such as yet
En Schuur and Wangshur Chiang. These physicians recommended it for
(40:23):
feverish diseases arising from both newly contracted and lurking pathogens.
Scalleon and prepared soybean decoction is especially suited for early
stage external invasion, when it may be difficult to judge
whether one is dealing with a cold damage or worm
pathogen disease. Although the basic formula contains only two simple ingredients,
(40:45):
their combined effect provides a significant potency. Accordingly, the Qing
dynasty physician Febo Chiang, who favored the use of such
general formulas wherever possible, noted, this formula is exceptionally good
at releasing the exterior and unblocking the young. Do not
collect it, do not neglect its use merely because it
(41:09):
is composed of herbs with a mild flavor. And so
I read this, and I go, I'm probably not using
this as often as I should. This is a great
little formula. And how great is it? Say to your patients,
get you know, for a day or two, have some
you know, like I would do, is have some miso soup,
you know. So Chen and Chen also has a small,
(41:30):
very small commentary on this formula. This is a mild
exterior releasing formula and has no cautions or contraindications, and
is therefore suitable for most people with exterior syndrome, So
again not a bad thing for someone who's going through
a cold. By the way, the one caution I would
have with miso soup is it often miso is has
(41:52):
a lot of salt, So that would be the one
caution I would have is with is having too much salt.
With that modification of this morning, so this is mild.
As we said, you might want to add a lot
of herbs, might add some herbs to this, and so
there are quite a few modifications for this. We'll go
over them briefly here. So if this formula, and these
are all from Shaid and his team. If this formula
(42:14):
fails to induce sweating, ad peraria radix gogun and simysifuga
raizoma or shang ma. Those are two very commonly used
extra releasing herbs cold cooling exter releasing herbs. If there's
still no sweating, ad e fedra herba mahuang, which of
course is banned at this point, but that's that's really
the ultimate herb for inducing sweating for pronounced chills and headache.
(42:38):
Add no top tier gy Rhizoma sue raidex chiang huo
so passion of Covid Redex fong fung and Schizennepidae Herba
jing j so those Again, those are also commonly used
external from they tend to be more on the warming side.
For pronounced cold with abdominal pain Zingabaros Rhizoma resons shehangjiang
(43:02):
that's our fresh ginger and brown sugar. Interesting for pronounced
fever with a sore and swollen throat. Add Scutularia radix,
huang chin guardina fru gerza, which is great orb for cooling.
Huang chi is very good for damp peate, and for
Scythia fruitus lean chow that's great for heat toxin. So
(43:24):
those are quite draining and all kind of go towards
the throat well, at least uh for Ccythia and chaw
goes for the throat as well, specifically for pronounced coughing
and hoarseness at Cicada periostracum chwan chon tweet. This is
the the the exoskeleton of trying to remember cicadas plant
(43:49):
Cooti redix jagong great for coughs, and Rcti fructus neo
bongza for concurrent turbid damnness with nausea, a stifling sensation, chest,
loss of taste, and a thick, greasy tongue coating. Add
pugas deamonis slash agatstaches herba or and you put torrii
(44:11):
herba peylon. Those are both good for damp yes for
common cold occurring in the spring or summer as a
result of a looking pathogen with a version to wind,
chills and fever, headache, sweating, or an absence of sweating,
irritability and thirst. Add some passion of coovia rdex fung
fung cod ratex jay gong city reticulate, pericarpium chen p
(44:36):
and army arm nassier siemen shingran that is apricot seed.
So those are the modifications. Let's talk about modifications. So
how would we modify this for you? Sheen Chen, save
the patient does Oh, we're still talking about modification. Sorry,
(44:58):
but now we're going to chen Chen. A little confused there,
Trenchen say, if the patient does not sweat after taking
the decoction, ad minister of the formula game with the
addition of gogen radix, Perraria lobate six grams rhizomas simysifuge.
So we already had that basically, and she had said
something very similar Shy in his team. The patient still
(45:19):
does not sweat after taking this decoction. Ad Ma Huang
administer the decoction again, so again very similar to in
fact exactly the same as twitch I just said and
his team uh And as mentioned earlier, this formula is
a related formula to song chure jaegung tongue according to
Chen and Chen, and the reverses true according to Hide
at All, song chure Jaegong tongue is an associated formula
(45:42):
to song chure tongue. Today's formula songture jagung tongue adds
platy coat, platkodonis, redix jaegong gardinier, fructis jerdza mente haplo, causis,
Herba boha that's field mint for ccythia fruit and choo
the serucary ratix gone sou that's licorice and fresh lofa
(46:05):
theory herba recens chian don ju ye just song chir tongue.
So those are the six additional herbs to song chur tongue,
and that is a great modification for this formula. Shide
and his team usually has other formulas that it compares
to our current formula. They do not in this case.
(46:26):
Are there are no comparison formulas for this formula. Biomedical indications.
Shide in his team say, with the appropriate presentation, this
formula may be used to treat a variety of biomedically
defined disorders, including upper respiratory tract infections, irdies, and the
very early stages of many respiratory infections Chen and Chen.
(46:52):
Given that this is related from it also does not
have a thorough monograph in this formula does not include
biomedical indications, which they usually are very good to include.
Science on this too is a little bit lacking. There
were no papers on this forma when searched for using Google,
using Google scholar or looking at the Cochrane Library love
(47:13):
the Cochrane Library. So really nothing that I could really
find it. And it's interesting because it's so basic. I
can see why I'm a lot of scientists. If I
were looking for a formula to study, I wouldn't, you know,
you know, consider this formula because it's really basic and
basically has food stuffs in it, so it's pretty straightforward.
Let's get into druggrab interactions. This is an interesting area
(47:36):
for this. So giving them both of the ingredients in
this formula are foods, one would would think there would
be little risk of drug rib interactions. However, there is
lots of research on soy and it's potential interactions with
syachroone P for fifteen P glycoprotein. So right there, we
have a little bit of an issue because this is
prepared so ibeans, so we don't really know what you know,
(47:59):
we could look at all the information on soy and
it may or may not apply to this prepared soy
being product that we have. So it adds a little
complexity to what we're talking about here. So there is
a good amount of evidence youing interactions. How are most
we're done on extracts of soy, specific constituents of soy
like Ginnstein or dietary quantities of soy. I know, it's
(48:23):
a lot more than you would be taking during this formula,
So again may or may not be useful. I mean,
because we're not looking at extracts of soy, which you
know sometimes concentrate things more than other things. We're actually
you know, you might say, a decoction is a kind
of extract. It is, it's a water extract, but it's
(48:44):
it's not a concentration. And often when we say an extract,
we mean a concentration of of what's extracted and specific constituents.
You know, we'll talk about that in just a second.
That plays a role here too. Ronas, who wrote a
paper says there is conclusive data to suggest that consumption
(49:06):
of dietary soy products and other isolates soy product isolates
and other soy products significantly alter the expression and activity
of cytochrome P for fifty enzymes in a species, organ
and cell type specific manners. So cychrolone P for fifty
versus one of heur main targets for drug of interactions.
We're always looking at that, and they say, He says,
(49:29):
these include deduction of cytochrome cyochrome P two subtypes and
three A subtypes, So several under those headings. Remember there's
subtypes of cydochroon P for fifty. We're particularly worried about
subtype three A four because that's what most drugs used
to metabolize. So if it's affecting three A four, which
this is saying it does could be an issue for
(49:50):
drug of interactions. Another earlier study, Williamson in two thousand
and six concludes no clinical reports and conflicting evidence between
effects of genestine and isolated the ingredient and the total
extract of soye ginestine inhibits various sachrome P for fifty
enzymes and peak glycoprotein, which is another target for drug
(50:13):
of interactions. But soya actract does not affect cytochrome P
for fifty three or four according to this study. In
other words, it may or may not have interactions, and
the evidence is still being debated, so you know, it's
hard for me to give a conclusion like does soy
and specifically just prepared soyveen as it is in this formula,
(50:35):
does this cause a drugg of interaction? And while there's
some evidence it might be increase the risks of a
drug er of interaction, I think the risks are still
pretty minor. We're taking in fairly low doses in this
in this form in this formula, when I look at
(50:56):
some of the specific ingredients, yeah, it affects all these
acacroone PEF for fifties, but some douce, some inhibit there's
all these different things, and I don't like saying there's
drugger of interaction without one thing, in particular, a clinical
study that shows it affects humans. There's lots and lots
of studies that say there are interactions between various constituents
and csarachropy for fifth ism glycoprotein, but not in humans.
(51:20):
They did it in test tubes, they did it in
rats and mice, but not in humans. And until it's
in humans, it's not really an interaction. May point to
the fact that there might be an interaction, so we
need to be aware of it, but it's not conclusive evidence,
and I don't think there's conclusive evidence here. What there
is conclusive evidence is that when you look at epidemiological
(51:41):
studies of soy and cultures that eat lots of soy,
there's a lot less cancer in those cultures and a
lot less other things happening, diseases happening in those cultures.
In other words, there seems to be a benefit of
soy in health. However, that doesn't take away all of
(52:03):
the different confounding factors, and so it may not be
the soy, maybe lots of other stuff. Cultures that have
a lot of soil, also walk a lot you know,
who knows we're working on that stuff. But I think
we're pretty safe to say there probably aren't strong Drugger
of interactions, but still need to keep in the back
of our mind that we need to be aware of it.
All Right, that was a lot on Drugger of interactions.
(52:25):
Let's move on, so concerns. Neither of our texts have
any contra indications for this formula, with Chet and Chat
going so far as to say it has no cautions
or contra indications and is therefore suitable for most people
with exterior syndromes, which we mentioned earlier. So I don't
think there's any major concerns. Like I said, if I'm
(52:46):
recommending miso soup to my patients as a quick and
easy way for this decoction to get in them, I'm
a little concerned about the salt intake, so might recommend
that they have plenty of fluids. But so we'll probably
recommend anyways and maybe not have a giant gallons of
it or anything along with those science for the salt.
(53:07):
So that would be my one concern in that context.
In the straight decoction, wouldn't worry about it at all,
all right, So that was our formula of today. Suncture
tongue or scallion and prepared soybean decoction, a mild but
useful formula for treating the first manifestations of a cold
(53:28):
or external attack. We started by discussing from a cognitcy
in several glycosides, and then we got into the formula
including its ingredients, commentary, the science, our concerns and cautions,
as well as its potential drug interactions. All in all,
another exploration of fascinating, easily concocted, especially if you're gonna
(53:48):
do that mesci version and useful Chinese formula. In two weeks,
we're going to be looking at another single Chinese herb
zieh su ye zi su Yeah, Prilla folium or simply
perilla leaf. This herb is another herb in the Chinese
(54:09):
medical subcategory of warm acrid herbs that release the exterior
and can be used in it used to comma feed
us and help seafood poisoning. In fact, you're probably aware
of this herb even if you've never heard of it before,
especially if you eat sushi. It's a little, uh, a
(54:30):
little mystery. We'll uncover. On this episode, as usual, we
will explore all the intricacies of this herb as well
as an explanation of its category, and as always we
will look at something a little different. Join us in
two weeks for another interesting episode. As for today, thank
(54:52):
you very much. If you like this podcast, please do
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(55:13):
Professional Development Activities at www dot Integrative Medicinecouncil dot org.
That's Integrative Medicine Council co o u n cil dot org.
Don't forget that twenty percent off with the code s
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(55:34):
with me at doctor Greg at Sperbserbs dot com or
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thank you so much for listening today. As usual we
have quite the bibliography, Thank you very much. The proceeding
(55:56):
was presented by doctor Greg Sperber. We would like to
thank Janelle for all our support and everybody else who
contributed to this program. Timothy Roger Campbell mm hmm