The Dr. Hyman Show

The Dr. Hyman Show

Welcome to The Dr. Hyman Show, the groundbreaking podcast redefining health in America and empowering you to take ownership of your health. Hosted by Dr. Mark Hyman—this show tackles the most pressing issues of our time: chronic disease, mental health, food policy and controversy, prevention and recovery, and longevity. In an era where our food system fuels disease and outdated healthcare models fail to address root causes, Dr. Hyman delivers evidence-based insights and expert interviews to help you become the CEO of your own health—something your doctor isn’t doing. The Dr. Hyman Show goes beyond the headlines to reimagine a food and healthcare system that protects health, unburdens our economy from the weight of chronic disease, supports the environment, and secures a vibrant future for all Americans. Whether you’re looking for cutting-edge protocols to transform your health, strategies to combat the chronic disease epidemic, or deep conversations about how wellness intersects with food, politics, and the environment, this podcast is your trusted guide. Rethink disease, claim your health, and join the movement for a healthier nation—tune into The Dr. Hyman Show today!

Episodes

August 25, 2025 55 mins
As women enter perimenopause and menopause, hormonal shifts—declining estrogen, progesterone, and testosterone—can ripple through nearly every system in the body, impacting bone density, cardiovascular health, metabolism, brain function, and sexual wellbeing. Misinterpretation of past research left millions fearful of hormone therapy, yet newer evidence shows that bioidentical hormones, started within a specific “window of opportun...
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In a world where healthcare often focuses on treating illness rather than promoting wellness, what does it really take to live a healthy, vibrant life? In this episode of The Dr. Hyman Show, I sit down with John Mackey, co-founder of Whole Foods Market, to explore his journey from building one of America’s most iconic food companies to rethinking health, purpose, and consciousness. We talk about his new venture, Love.Life, and how...
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Relationships have the power to change lives in ways both visible and hidden. Deep, supportive bonds can quiet inflammation in the body, protect against disease, and anchor people through decades of triumphs and trials. Communities that come together—whether in small groups at a church or around a shared health goal—often achieve far more than individuals working alone, sometimes transforming their health on a massive scale. Lifelo...
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With so much conflicting health advice online, it’s no wonder people feel overwhelmed by food choices. Is saturated fat really the enemy? Are seed oils as harmful as some headlines claim? And how do we know what’s actually true?  In this episode of The Dr. Hyman Show, I sit down with nutrition researcher and author Simon Hill to make sense of the latest science and help you cut through the confusion. You can watch our full conve...
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Medicine stands at the threshold of a new era, where artificial intelligence and systems biology are working hand in hand to make care more personal, predictive, and precise than ever before. AI is already improving diagnostic accuracy, automating administrative tasks, and uncovering patterns in data—like retinal scans or genomics—that humans often miss. Rather than replacing doctors, AI enhances their ability to deliver mo...
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This special bonus episode features Dr. Todd LePine from the UltraWellness Center, diving into how functional medicine can help reverse fatty liver disease—an often-overlooked condition that’s quietly affecting millions. While conventional care may miss early warning signs or focus solely on medication, Dr. LePine and I take a deeper look at the root causes. We also walk through a real patient case that shows how liver fat can be ...
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Our healthcare system is broken—and it’s not by accident. On this episode of The Dr. Hyman Show, I’m joined by Brigham Buhler, a former pharmaceutical rep turned healthcare entrepreneur, to explore how misaligned incentives across pharma, insurance, and government are undermining patient care.  This conversation is about more than just exposing the problem. It’s about empowering individuals. Watch our full discussion on my YouTube...
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Social media platforms are designed to hijack our brain’s reward system, keeping us hooked through endless dopamine hits. This constant stimulation fragments our attention, reshapes our behavior, and can lead to burnout, anxiety, and even addiction—especially in developing brains. The more we scroll, the more we crave quick hits of novelty, making it harder to tolerate boredom or engage in deeper, more meaningful tasks. And while a...
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On this episode of The Dr. Hyman Show, we’re exploring the emerging science of metabolic psychiatry. My guest, Dr. Iain Campbell, is a researcher at the University of Edinburgh and someone who has lived with bipolar disorder himself. He brings a rare dual perspective as both a scientist and a patient to this critical conversation.  Together, we discuss what’s really driving psychiatric conditions like bipolar disorder and why a sy...
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ADHD and other brain-based conditions such as depression, autism, and even schizophrenia are increasingly understood as inflammatory disorders of the brain—deeply rooted in the complex interplay between genetics, environment, and lifestyle. Many individuals go undiagnosed for years, internalizing harmful labels like “lazy” or “difficult,” until the weight of unaddressed symptoms finally becomes too much. But there is hope: Function...
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On this episode of The Doctor Hyman Show, I sit down with Dr. Eric Topol—renowned cardiologist, geneticist, and founder of the Scripps Research Translational Institute—to talk about the future of disease prevention. From AI diagnostics to genetic risk scoring, we explore the tools that could help stop Alzheimer’s and other chronic diseases before they start. This is one of the most hopeful conversations I’ve had about what’s ahead...
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Longevity isn’t just about adding years to life—it’s about adding life to those years. At the heart of lasting vitality are the often-overlooked essentials: deep social connection, a clear sense of purpose, and a mindset filled with optimism. These emotional and relational foundations are just as critical as what’s happening inside the body. Thanks to emerging diagnostics and the growing field of functional and longevity medicine, ...
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What if the key to healing depression isn’t another pill but a profound shift in consciousness? On this episode of The Dr. Hyman Show, I talk with Dr. Robin Carhart-Harris, one of the world’s leading psychedelic researchers, about how these compounds unlock plasticity in the brain and offer new hope for people with treatment-resistant mental health challenges. From trauma recovery to the entropic brain principle, this is a conve...
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Sunlight has long been vilified for its link to skin cancer, yet hiding from it entirely may be costing us far more. Vitamin D, made primarily through sun exposure, plays a pivotal role in everything from bone strength and immune defense to mood regulation, cancer prevention, and even longevity. Shockingly, over 80% of people have levels too low to unlock its protective powers—putting them at greater risk for chronic illness, and e...
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This special bonus episode features Dr. Cindy Geyer from the UltraWellness Center, diving into how functional medicine approaches high blood pressure — and why treating the root cause means looking far beyond salt and stress. In this conversation, Dr. Geyer walks through the case of a woman with longstanding “white coat” hypertension, family history of cognitive decline, and no clear answers from conventional care. By investigatin...
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We often think that better health is just a matter of trying harder, but science tells a different story. On this episode of The Dr. Hyman Show, I sit down with Arianna Huffington to explore why willpower isn’t enough—and what actually drives meaningful, lasting change. Arianna shares how her work with Thrive AI Health is helping people build better habits through microsteps, personalization, and community. Catch the full conversa...
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Not long ago, conditions like Alzheimer’s were rare, but today, nearly one in two people over 80 are diagnosed with it. In contrast, in places like the Amazon, dementia affects only about one in a hundred—highlighting how modern lifestyle plays a major role in brain health. The brain isn’t an isolated organ; it’s deeply influenced by diet, sleep, movement, stress, toxins, and emotional well-being. Many people who once struggled wit...
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This is the full, unedited version of Dr. Hyman’s conversation with Daniel Schmachtenberger. The original episode was edited for pacing and clarity. This extended cut includes the entire four-hour dialogue as it happened — a deep dive into the systemic roots of chronic disease and the future of real prevention.
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I recently sat down with Daniel Schmachtenberger, a strategist and founding voice behind The Consilience Project, to explore the deeper systems fueling today’s chronic disease epidemic. On this episode of The Dr. Hyman Show, Daniel shares a powerful perspective on how modern life impacts our health and what it will take to create lasting change. Here’s what we cover: • Why chronic disease today is largely “man-made” and what t...
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Muscle plays a powerful role in keeping us healthy and living longer, but most people start losing it after age 30—and that loss can drive chronic disease and early aging. The good news is that strength training and eating enough protein can help prevent this decline, improve blood sugar control, and reduce the risk of issues like diabetes, dementia, heart disease, and depression. Muscle isn’t just for movement—it acts like an orga...
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