Solve for X: Innovations to Change the World

Recent advances in AI have fundamentally changed how we predict the weather, making forecasting cheaper, faster and better — we can now track even the most unusual weather event with almost pinpoint accuracy. Such accuracy has never been more urgent. With climate change making weather more extreme, unpredictable and dangerous, knowing how much rain a storm may bring, or how long a drought could last, can be a matter of life a...

Episode summary: The head-spinning ascent of AI is a story of scientific innovation, but it’s also, fundamentally, a story about money. Between 2013 and 2024, AI netted about U.S.$1.6 trillion of global corporate and private investment; it’s estimated that by the end of this year that number will reach U.S.$2.5 trillion. How this massive investment is transforming — and will transform — the way we live ...

Thanks largely to advances in AI, robots are now capable of things never before possible: picking delicate vegetables, moving heavy goods deftly around a warehouse, making pizzas. But there are still limitations to even the most sophisticated and expensive machines. Replicating human dexterity, for example, remains a surprisingly fiendish challenge. While some experts talk about an imminent “ChatGPT moment” for robotics...

The housing crisis is fundamentally a health problem. Decades of research show that people experiencing homelessness spend twice as long in the hospital, cost the healthcare system double and have a life expectancy half that of the average Canadian. In this special episode of Solve for X: Innovations to Change the World, recorded live at a MaRS Morning event, host Manjula Selvarajah sits down with primary care physician Dr. Andrew ...

There are few neurodegenerative diseases as devastating as Huntington’s. It’s sometimes likened to having Parkinson’s, ALS and Alzheimer’s all at the same time, with symptoms that include progressive motor dysfunction, cognitive decline and behavioural change. It’s also hereditary — if a person has the faulty gene that causes the disease, there’s a 50 percent chance their children will...

Brain-computer interfaces (BCIs) have been allowing humans to control objects with their minds for nearly half a century. But in recent years, thanks partly to advances in AI, the technology has evolved dramatically; wearable and implantable devices are now being used to restore speech and movement to stroke survivors, alleviate depression and treat pain. While companies like Elon Musk’s Neuralink grab headlines, a somewhat q...

The fashion industry has its fair share of dirty secrets, but one of the lesser-known is how much it pollutes our waterways. Every year, garment factories use as much as 2 trillion gallons of water to dye clothes, and most of that water, now filled with harmful chemicals, flows untreated into rivers, streams and lakes. Those pollutants can turn rivers black, harm marine life and cause cancer. Macarena Cataldo, a chemical engineer b...

There’s no denying that technology plays — and will continue to play — a critical role in addressing the climate crisis. But could super-intelligent AI actually solve the problem for us, as several tech billionaires claim? Or is this over-reliance on speculative technology simply a way to distract us from tackling big, real-world problems. Manjula Selvarajah sits down with astrophysicist and author Adam ...

Our energy grid is something most of us only think about when it isn’t working. But growing demand for electricity is placing an even greater strain on a system that’s already facing increased pressure from extreme weather events. Can we build a more sustainable and dependable grid? In this episode, which originally aired September 2022, we explore how when it comes to climate change the challenge of greening the grid i...

As you may have heard, solar energy is having a moment. Thanks to several technological breakthroughs, it’s now the cheapest form of energy generation in most places on Earth. This past summer, for the first time ever, it became the EU’s main source of electricity, and many other parts of the world — Pakistan, Nigeria and most famously, China — are likewise in the midst of a solar boom of astonishing sp...

By uncovering critical sex-based differences related to brain and metabolic health, researchers Gillian Einstein and Minna Woo are making the case that tailored interventions are key to improving health outcomes for women — and everyone else. Through their work exploring how conditions from Alzheimer’s to kidney disease can have varied effects depending on a patient’s sex, they underscore what the medical communit...

The hotter it gets outside, the more we use air conditioning, and the more we use air conditioning, the hotter it gets. AC units and refrigeration combined adds up to 10 percent of global greenhouse gas emissions. But how can we solve this cooling paradox? Building on last episode’s conversation with the UN’s global chief heat officer, host Manjula Selvarajah meets the experts harnessing novel innovations to keep cities...

Extreme heat waves are anything but normal, but they’re quickly becoming the new reality. The 10 hottest years on record have all happened in the last decade. And because temperatures in urban centres can be 10 to 15 degrees Celsius higher than surrounding areas, cities can be dangerous places to be when the mercury rises — particularly for the elderly, those with pre-exisiting health conditions as well as poorer popula...

A quarter of Canada’s trees are at risk, and upwards of a million species around the world face extinction in the decades to come. Restoring nature is essential to survival — it can make communities more resilient to climate change, it can regrow areas destroyed by increasingly intense wildfires and it can help reduce atmospheric carbon. But repairing ecosystems is not as simple as planting seeds. In this special episod...

Experts are calling antimicrobial resistance the silent pandemic: Each year, AMR is responsible for more than a million deaths around the world. It’s a threat to our health that’s been exacerbated by the very medications used to treat it. This problem has been growing for decades, and healthcare practitioners have responded by developing new antibiotics. “And then,” says Dr. Scott Weese, a global expert in a...

Modern medicine has a dirty secret. While plastics have revolutionized healthcare, research increasingly shows that they’re also making us sick. Items such as PPE, syringes, gowns, IV bags and protective wrappings have allowed for a higher standard of sanitary patient care that vastly reduces the risk of cross-contamination. But all that plastic is adding up. Nearly a third of healthcare waste is plastics, and a report on 110...

The wildfire that devastated Fort McMurray in 2016 burned more than 579,000 hectares of land, drove 88,000 people from their homes and caused nearly $10 billion in damages. It’s often seen as an outlier, a freak natural disaster. But extreme wildfires, like those that tore through Los Angeles earlier this year, are becoming more intense and harder to control. “We all saw the smoke, and too many of us have seen the fire,...

Can AI unravel the mysteries of human biology? Could it help design specialty treatments and cures for disease? Geoffrey von Maltzahn and his team at Generate:Biomedicines are bullish on both counts. AI has greatly accelerated progress in genome engineering, bioengineering and nanotechnology and they are getting closer to developing tailored therapeutics. “Six years ago, this was a crazy idea,” he says. “We’...