Addiction Medicine Journal Club
We believe that addiction is a disease that can be treated, and we want to help you stay up to date with the latest research that you can use in your addiction medicine practice.
Episodes
September 7, 2026 • 32 mins
We discuss an article about the benefits of continuing buprenorphine, methadone, and naltrexone long-term.
Hayes CJ, Raciborski RA, Acharya M, Noor NB, Nunes EV, Winhusen TJ. Evaluating the optimal duration of medication treatment for opioid use disorder. Addiction. 2026 Apr;121(4):922-933. doi: 10.1111/add.70211. Epub 2026 Jan 7. PMID: 41501983; PMCID: PMC12980296.
We also discuss increasing reimburs...
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August 24, 2026 • 52 mins
71-80 Round-Up
Quick summaries of our last 10 articles, for busy people.
71. Buprenorphine and Dental Problems
72. Symptom-Triggered Alcohol Withdrawal Management Over
Telemedicine
73. Long-Term Opioid Use After a First Prescription
74. Quick-Start Injectable Buprenorphine
75. Contingency Management for Stimulant Use Disorder and
Mortality
76. Injectable Buprenorphine in Pregnancy
77. Epic’s Opio...
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August 10, 2026 • 32 mins
In episode 81 we discuss using mirtazapine to treat methamphetamine
use disorder.
McKetin R, Shoptaw S, Saunders L, et al. Mirtazapine for Methamphetamine Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2026;83(6):581–589. doi:10.1001/jamapsychiatry.2026.0159
We also discuss behavioral treatments added to buprenorphine,
and how the FDA is promoting flavored nicotine products.
...
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July 27, 2026 • 37 mins
In episode 80 we discuss phenobarbital for alcohol withdrawal in the hospital.
Wolpaw BJ, Oren H, Quinnan-Hostein L, Et al. Hospital-Wide
Implementation, Clinical Outcomes, and Safety of Phenobarbital for Alcohol Withdrawal. JAMA Netw Open. 2025 Aug 1;8(8):e2528694.
We also discuss DEA scheduling of 7-OH (from kratom) and the Trump administration’s pro-alcohol policies.
The Hill: DEA moves to ban opioid-like k...
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July 13, 2026 • 31 mins
In episode 79 we discuss an article about starting long-acting injectable buprenorphine without a sublingual test dose.
Rosenwohl-Mack S, Heeney M, Samuel L, Anderson E, Herring AA, Sirey LR, Peterson D, Bazazi AR, Snyder H, Suen LW. “Outpatient initiation of direct-to-inject buprenorphine.” Drug and alcohol dependence vol. 278 (2026): 113011. doi:10.1016/j.drugalcdep.2025.1130...
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June 29, 2026 • 33 mins
In episode 78 we discuss treating alcohol use disorder in patients with severe liver disease.
Sundaresh R, Singh J, Meza J, Saab S, Shetty A. Medications for Alcohol Use Disorder Among Patients With Severe Alcohol-Related Liver Disease. JAMA Netw Open. 2026;9(2):e2559016. doi:10.1001/jamanetworkopen.2025.59016
We also discuss...
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June 15, 2026 • 63 mins
We love a good poster session. This episode we are joined by Dr. Anthony Accurso to review some of our favorite posters from the American Society of Addiction Medicine’s 2026 Annual Meeting.
All the Posters from ASAM 57
Posters profiled here:
12: Real-World Analysis of Buprenorphine-Precipitated Opioid Withdrawal: A Multicenter Study
38: Co-Located Bridge Clinic/Withdrawal ...
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June 1, 2026 • 37 mins
Finally, an external validation of Epic’s controversial risk of opioid abuse and overdose model.
Hooker, S.A., Rossom, R.C., Haapala, J. et al. External Validation of Epic’s Risk of Opioid Abuse and Overdose Model Among Primary Care Patients in Three Health Systems. J GEN INTERN MED (2026).
We also discuss financial consequences of online sports betting, and Trump&...
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May 18, 2026 • 41 mins
A new randomized controlled trial of injectable buprenorphine in pregnancy.
Winhusen TJ, Lofwall MR, Kropp F, et al. Extended-Release vs Sublingual Buprenorphine in Pregnancy Through 12 Months Post Partum: A Randomized Clinical Trial. JAMA Intern Med. Published online March 16, 2026.
We also discuss the kindling effect in opioid withdrawal, and how insurance ch...
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May 4, 2026 • 28 mins
In episode 75 we discuss the mortality benefit of contingency management for stimulant use disorder.
Coughlin LN, Tomlinson DC, Zhang L, Kim HM, Frost MC, Khazanov G, McKay JR, DePhilippis D, Lin LA. Contingency Management for Stimulant Use Disorder and Association With Mortality: A Cohort Study. Am J Psychiatry. 2025 Nov 1;182(11):1016-1023.
We also discuss telemedicine regulations.
ASA...
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April 20, 2026 • 30 mins
In episode 74 we discuss an article about starting injectable buprenorphine after just one sublingual dose.
Shiwach R, Le Foll B, Alho H, et al. Rapid vs Standard Induction to Injectable Extended-Release Buprenorphine: A Randomized Clinical Trial. JAMA Netw Open. 2025;8(10):e2537319.
We will be presenting high-yield articles that changed our practices at the Pennsylvania Society of Addiction Medi...
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April 6, 2026 • 36 mins
In this episode we review 4 more practice changing articles with real-life case studies.
Söderpalm B, Et al. Efficacy and safety of varenicline and bupropion, in combination and alone, for alcohol use disorder: a randomized, double-blind, placebo-controlled multicentre trial. Lancet Reg Health Eur. 2025 May 13;54:101310.
Hendershot CS, Et al.&nbs...
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March 30, 2026 • 36 mins
In this episode we review 4 practice changing articles with real-life case studies.
Coughlin LN, Et al. Contingency Management for Stimulant Use Disorder and Association With Mortality: A Cohort Study. Am J Psychiatry. 2025 Nov 1;182(11):1016-1023.
Shiwach R, Et al. Rapid vs Standard Induction to Injectable Extended-Release Buprenorphine: A ...
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March 23, 2026 • 42 mins
In episode 73 we discuss the risk of long-term opioid use after an initial opioid prescription.
Smith AM, Shah A, Martin BC. An updated view on the influence of initial opioid prescription characteristics on long-term opioid use among opioid naïve patients. Drug Alcohol Depend. 2024 Dec 1;265:112463.
We also discuss alcohol’s place in the new dietary guidelines, and Canada’s drug decr...
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March 9, 2026 • 35 mins
In episode 72 we discuss a telemedicine protocol for outpatient symptom-triggered alcohol withdrawal management.
Sloan ME, Ngoy A, Xiao KB, Barker B, Buckley L, Fodor M, Hardy K, Hendershot CS, Kahan M, La Fleur S, Le Foll B, Manicone M, Sanches M, Simpkin E, Quilty LC, Wyman J, Tang VM, Bozinoff N. Symptom-Triggered Alcohol Withdrawal Management Delivered Over Telemedicine. J Addict Med. 2025 Nov-Dec 01;19(6):708-71...
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March 2, 2026 • 34 mins
In episode 71 we discuss dental problems caused by buprenorphine.
Tuan WJ, Clebak KT, Jawadi E, Snyder J, Zgierska AE. Risk of Oral Health Problems in Adults With Opioid Use Disorder Treated With Transmucosal Buprenorphine. J Addict Med. 2025 Sep-Oct 01;19(5):529-535.
We also discuss over-the-counter naltrexone and what RFK said at his senate confirmation hearing about substance use disorder.&nbs...
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February 23, 2026 • 54 mins
Quick summaries of our last 10 articles, perfect for busy people!
61. Safety of Buprenorphine/Naloxone vs. Buprenorphine in Pregnancy
Straub L, et al. Comparative Safety of In Utero Exposure to Buprenorphine Combined With Naloxone vs Buprenorphine Alone. JAMA. 2024 Sep 10;332(10):805-816.
62. Naltrexone Pills vs Injections for Alcohol Use Disorder
Magane KM, et al. Oral vs Extended-...
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December 15, 2025 • 47 mins
In episode 70 we discuss an
article about prescription stimulant misuse.
Han B, Jones CM, Volkow ND, et
al.Prescription
Stimulant Use, Misuse, and Use Disorder Among US Adults Aged 18 to 64
Years.
JAMA Psychiatry. 2025;82(6):572–581.
We also discuss the ASAM
toolkit for addressing problems at the pharmacy with buprenorphine,
and results of the 2024 NSDUH study.
ASAM:Addressing
Issues at the Pharmacy with Buprenorp...
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December 1, 2025 • 27 mins
In episode 69 we discuss cytisinicline for smoking cessation.
Rigotti NA, et al. Cytisinicline for Smoking Cessation: The ORCA Phase 3 Replication Randomized Clinical Trial. JAMA Intern Med. 2025 Jun 1;185(6):648-655.
We also discuss treating opioid use disorder in nursing homes and compulsive TikTok scrolling.
Carolina Public Press: NC nursing home lawsuit settlement could expand access for people with drug issues
Me...
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November 17, 2025 • 40 mins
In episode 68 we discuss an article about adding behavioral treatments to buprenorphine for opioid use disorder.
McHugh RK, et al. Behavioral Therapy as an Adjunct to Buprenorphine Treatment for Opioid Use Disorder: A Secondary Analysis of 4 Randomized Clinical Trials. JAMA Netw Open. 2025 Aug 1;8(8):e2528529.
We also discuss online gambling addiction, and neuroanatomy that predisposes adolescents to addiction.
Stat...
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