The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show promotes a healthy world, and in order to have a healthy world, we must have transparent conversations. This show is dedicated to such conversations as the listener; your education, understanding, strength, and health are the primary focus. The goal of this show is to provide you with a framework for navigating the health and wellness space and, most importantly, being the champion of your own life. Guests include highly trustworthy professionals that bring both the art and science of wellness aspects that are both physical and mental. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician who serves the innovators, mavericks, and leaders in their fields, as well as working closely with the Special Operations Military. She is the founder of the Institute of Muscle-Centric Medicine® and serves patients worldwide.

Episodes

July 9, 2026 23 mins

You might think microplastics are just an environmental nuisance that passes through your body, but the latest tissue studies tell a very different story. As a physician, Dr. Gabrielle Lyon breaks down where the science lands, past both the fear-mongering and the dismissiveness.

In this solo episode, Dr. Gabrielle Lyon discusses:

  • Why over 58% of patients in a landmark NEJM study had plastic embedded in their arterial plaque and t...
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You've been told that 10,000 steps a day is enough to keep you healthy but when it comes to your bones and your muscles, walking falls short, and the science explains exactly why. The real drivers of strength, bone density, and lasting health are load, intensity, and resistance, not just movement.

In this episode, Dr. Gabrielle Lyon sits down with Dr. Alyssa Olenick, a PhD in exercise metabolism and ultramarathoner who blends endura...

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You were told your testosterone is "normal" so why do you still feel exhausted, weak, and off? The number on your lab report was never built for you, and your own genetics may be the reason it doesn't match how you feel.

In this solo episode, Dr. Gabrielle Lyon discusses:

  • Why the standard 300–1000 ng/dL range ignores your age, comorbidities, and genetics, and why two men with identical labs can feel completely different
  • How ...
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The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4gCmoNR

For 40 years you've been told 0.8 grams of protein per kilogram is "enough" but the scientists who contributed the reports behind the new 2025–2030 Dietary Guidelines say not a s...

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The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked.

In this solo episode, Dr. Gabrielle Lyon discusses:

  • Why the same drug class can improve sexual function in men with obesity while potent...
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You might think more cardio is the key to aging well but Lisa Smith-Batchen, who has run 135 miles through Death Valley ten times, says it's strength that actually carries you through the decades.

In this episode, Dr. Gabrielle Lyon sits down with Lisa Smith-Batchen, one of the most decorated ultra-endurance athletes in American history and a 10-time Badwater 135 finisher, to discuss:

  • Why being strong matters more than being fast...
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What does it actually mean to win at the highest level? In this powerful compilation, I’m with 2024 CrossFit Games champion James Sprague, 2023 CrossFit Games champion Laura Horvath, and legendary endurance coach Chris Hinshaw to unpack the mental game behind elite performance, the vulnerability that follows victory, and why champions are often more fragile in the moments just after they win. What does winning mean to you rig...

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Most men think erectile dysfunction is a bedroom problem and low testosterone is just a fact of getting older. This roundtable makes the case that both are early warning lights for your heart, your metabolism, and your long-term health and that ignoring them can cost you a decade.

In this episode, Dr. Gabrielle Lyon sits down with urologists and men's health specialists Dr. Mohit Khera, Dr. Larry Lipshultz, and Dr. Tobias Köhler to ...

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Your ego isn’t the enemy, but if you’re not actively controlling it, it is running your team, your home, and your most important relationships. Jamie Cochran, COO of Echelon Front, has spent 13 years helping leaders fix the root cause most of them never look for.

The Women’s Leadership Assembly live event runs January 5–7, 2027 in Palm Springs. A free monthly webinar series runs year-round. More details here:...

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Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack.

In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in men's sexual health, to discuss:

  • Why ED is a symptom of vascular health, not a standalone disease and how the artery feeding the heart is rough...
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Most people think the cholesterol number on their lab report tells them whether their heart is at risk. But former National Lipid Association President Dr. Kevin Maki explains that LDL is just one piece of a much bigger picture and focusing on it alone can mean missing the markers that matter most.

In this episode, Dr. Gabrielle Lyon sits down with Dr. Kevin Maki, former President of the National Lipid Association and co-editor-in-c...

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Colorectal cancer is now the leading cancer killer in adults under 50, and patients in their 20s are presenting with metastatic disease that has nothing to do with family history. Most physicians are still telling young patients with rectal bleeding that it's probably just hemorrhoids and that's costing lives.

In this episode, Dr. Gabrielle Lyon sits down with Dr. Michelle Pearlman, a board-certified gastroenterologist and founder o...

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Most parents are quietly paving the road their kids were supposed to learn to walk on by themselves and Jocko Willink has spent 20 years watching what happens when that road is too smooth.

In this episode, Dr. Gabrielle Lyon sits down with Jocko Willink, retired Navy SEAL commander, founder of Echelon Front, and bestselling author of Extreme Ownership and Discipline Equals Freedom, to discuss:

  • Why the "apex parent / apex kid" min...
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Most men don't know they have a pelvic floor, and most doctors aren't trained to look for dysfunction in it. The result: testicles are being surgically removed for pain that's actually neuropathic, at double the rate of a far more effective nerve-sparing procedure.

In this episode, Dr. Gabrielle Lyon sits down with Dr. Susan Macdonald, a board-certified urologist, surgical program director at Penn State, and one of only ~30 U.S. spe...

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Most people are chasing the wrong version of strength and paying for it with pain, poor movement, and a body that breaks down faster than it should. In this episode, Dr. Gabrielle Lyon sits down with Mark Bell, elite powerlifter, entrepreneur, and founder of Slingshot, to discuss:

  • Why strength training is essential at every age but most people are defining "strength" too narrowly
  • How modern life has created an "exercise deficienc...
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We are living through one of the most significant shifts in medicine in generations, and most people don’t fully understand what it means. Dr. Christle Guevarra joins me to zoom out on the entire GLP-1 landscape; from the drug’s origins as a modest diabetes treatment in 2005 to today’s third-generation medications still moving through clinical trials, and what all of it means for the future of obesity, performance...

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The moment you decide to show up publicly, you open the door to opinions from people who would never say those things to your face. Dominique Sachse, journalist, author, and content creator who has lived her life on camera for over three decades, gets honest about what it costs to put yourself out there, why online cruelty is a psychology problem more than a content problem, and how “Teflon Dom” developed the thick skin...

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Only nine scientists were asked to advise on the 2025 Dietary Guidelines for Americans, and Dr. Tom Brenna was one of them. In this conversation, he pulls back the curtain on how dietary guidelines are actually made, why the process has never been the same twice, and what it was like to watch a decades-old saturated fat recommendation get carried forward despite a lack of evidence supporting it at the level of total mortality. This...

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In a world flooded with conflicting health advice, how do you actually figure out what’s true? Dr. David Allison, one of the most rigorous scientific minds in obesity and nutrition research, shared the exact framework he uses to evaluate evidence, from peer-reviewed trials to podcast recommendations to AI-generated summaries. He explains the difference between trusting science as a process and trusting individual studies, why...

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Up to 70% of dementia may be preventable, so why aren’t more people talking about what actually drives cognitive decline? In this episode, I’m with Dr. Tommy Wood, neuroscientist and author of “The Stimulated Mind,” to explore the lifestyle levers that protect your brain across a lifetime. Learn how white matter hyperintensities develop and whether they can reverse, what MCTs and ketones actually do for a gl...

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