Clearly Hormonal

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Dr. Komal Patil-Sisodia, obesity advocate Michael Donnelly-Boylen, and Dr. Matthea Rentea explain why they withdrew from a planned ADA-hosted webinar in support of a broader boyco...

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Dr. Komal Patil-Sisodia continues the PMOS Awareness Month series by walking through where GLP-1 medications, like semaglutide and tirzepatide, fit into PMOS treatment. She explai...

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Many people picture PMOS (polyendocrine metabolic ovarian syndrome, formerly known as PCOS) as a condition tied to weight gain. But the diagnostic criteria never mention body size...

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PMOS Awareness Month kicks off with a reframe: PMOS is not a condition that resolves once your cycles regulate or once you're done having kids. It is a lifelong cardiometabolic co...

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On Women's Equality Day, host Dr. Komal Patil-Sisodia revisits an idea from an early episode of Clearly Hormonal: the menopause penalty, the disproportionate income loss, leadersh...

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Two women get the same diagnosis, PMOS (formerly known as PCOS), and end up with completely different symptoms. One has irregular periods, acne, and high androgens. The other has ...

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Perimenopause is having a cultural moment, and endocrinologist Dr. Komal Patil-Sisodia is glad it is, but in this launch episode of Clearly Hormonal, she pushes back on social med...

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Endocrinologist Dr. Komal Patil-Sisodia defines peptides as short amino-acid chains (with examples like insulin) and notes that any package or claim stating “contains peptid...

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Dr. Komal Patil-Sisodia explains that headlines claiming “FDA approves peptides” are misleading: an FDA advisory committee narrowly voted to recommend adding six pepti...

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Type 1 diabetes isn't just a childhood disease, and it isn't caused by sugar, weight, or lifestyle. In this episode, Dr. Komal Patil-Sisodia breaks down why type 1 diabetes is so ...

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Type 2 Diabetes Isn't a Moral Failing: Genetics, Hormones, Stigma, and the Truth About Insulin

If you've ever been told — or told yourself — that your type 2 diabet...

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Getting diagnosed with Hashimoto's can feel overwhelming, especially after spending five minutes online. Suddenly you're told to eliminate gluten, avoid broccoli, stop eating soy,...

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One in four women will have some degree of thyroid dysfunction after menopause — so it's not unreasonable to test it. But Dr. Komal Patil-Sisodia says the real problem isn't...

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Picture three women. One is spitting into four little tubes throughout the day, mailing them off to a lab, hoping to finally get answers about her "adrenal fatigue." Another has b...

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“My adrenals are shot.” If you’ve said some version of that sentence this year, Dr. Komal Patil-Sisodia believes that you feel terrible—she just wants you ...

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Dr. Komal Patil-Sisodia records live from her hotel room on the final night of the ADA 86th Annual Scientific Sessions in New Orleans — still processing what she witnessed e...

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On May 12, 2026, The Lancet published the results of a 14-year global effort: Polycystic Ovarian Syndrome (PCOS) has been officially renamed Polyendocrine Metabolic Ovarian Syndro...

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The number-one cause of death in women is still heart disease — and perimenopause is where your cardiovascular risk starts to quietly climb. This week, Dr. Komal sits down w...

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Heart disease has long been framed as a “man’s disease” – but women are being missed, misdiagnosed, and overlooked in ways that can be life-threatening, es...