Longevity Junky

Can Alzheimer’s be reversed without drugs?

Dr. Dean Ornish says yes—and he has the clinical data to prove it. In this episode of Longevity Junky, Nikki and Buck sit down with the father of lifestyle medicine to explore a groundbreaking study showing how diet, exercise, stress reduction, and community can actually stop—or even reverse—early-stage Alzheimer’s. From the science of neuroplasticity to the power of social support, thi...

Get ready for some of the wildest, most jaw-dropping medical stories ever shared on Reddit. From ER scammers faking injuries for pain meds… to DIY tracheotomies, exploding intestines, and near-fatal sex injuries—these real-life cases are as unbelievable as they are horrifying.

Join Dr. Buck Joffrey and Nikki Leigh as they break down these totally unhinged Reddit stories with useful medical insights and some humor along the way.

What if preserving your body after death wasn’t science fiction—but science in progress?

In this mind-expanding conversation, James Arrowood of Alcor dives deep into the science and ethics of cryonics, explaining how ultra-cold preservation of human tissue could transform the future of medicine, organ banking, and even space travel. Learn how cryonics works, how Alcor operates as a non-profit, and what it means for our understan...

Discover how AI is revolutionizing personalized nutrition, diet tracking, and longevity in this episode of Longevity Junky. Caltech-trained physicist and AI entrepreneur Dr. Dmitriy Richard Starson reveals the tech behind his groundbreaking platform that analyzes your meals through photos and voice—no more tedious logging. Learn how AI can tailor your food choices, improve metabolic health, and even help doctors deliver better care...

Is boredom slowly killing you? Cognitive neuroscientist Dr. James Danckert joins Longevity Junky to break down the science of boredom—what it does to your brain, how it’s linked to depression, addiction, even heart disease, and why your response to boredom could affect your longevity. Plus, why some people shock themselves out of boredom (literally).

Learn more about Dr. James Danckert:

https://www.jamesdanckert.com/about

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Did you know microplastics could be silently damaging your hormones, fertility, and heart health? In this explosive episode, Dr. Leonardo Trasande—NYU professor, bestselling author, and global leader in environmental pediatrics—joins Buck and Nikki to reveal how these invisible plastic particles are infiltrating our bodies through food, water, and even air. Learn how microplastics disrupt your endocrine system, spike inflammation, ...

What supplements do two longevity junkies actually take? In this episode, Dr. Buck Joffrey and Nikki Leigh reveal their personal daily supplement stacks—the real-life regimens they follow to stay sharp, healthy, and (hopefully) young forever.

But here’s the kicker… not all supplements on store shelves are what they seem. Buck shares the shocking results of a study revealing that nearly half of herbal supplements don’t even conta...

What if rethinking relationships could unlock deeper connection, emotional well-being, and even longevity? In this episode of Longevity Junky, Nikki and Buck sit down with Dr. Joli Hamilton—research psychologist, certified sex educator, and relationship coach—to explore the world of consensual non-monogamy, jealousy, and alternative relationship dynamics.

Dr. Joli shares her personal journey from monogamy to a cohabiting triad, ...

Oscar-winning screenwriter and five-time world champion triathlete—Lesley Paterson doesn’t just break barriers; she obliterates them. From pushing through brutal endurance races to fighting for All Quiet on the Western Front, her mindset is an absolute masterclass in resilience. We dive into her elite fitness strategies, how she overcame chronic Lyme disease, and the shocking connection between metabolic health and cancer.

Learn...

In this episode of Longevity Junky, Buck Joffrey and Nikki Leigh sit down with David Mark Dror, author of Investors in Longevity, to explore the multi-billion-dollar investments driving longevity breakthroughs. Discover how Jeff Bezos, Peter Thiel, and major biotech firms are funding research in:

- Gene therapy and cellular reprogramming to slow aging

- AI-driven drug discovery for life extension

- Regenerative medicine and st...

How do you maximize muscle growth? What’s the optimal way to train for hypertrophy? Dr. Mike Israetel, fitness and performance expert, joins Buck Joffrey and Nikki Leigh to break down the science of building muscle—from protein timing to training volume and even future muscle-enhancing drugs. Plus, insights on sleep, recovery, and how genetics impact gains.

Learn more about Dr. Mike Israetel:

https://www.instagram.com/drmikeisrae...

Buck and Prof Glen Jeffery dive deep into the science of red light therapy, revealing how it boosts mitochondrial function and potentially slows aging. He shares groundbreaking insights from clinical trials, showing how red light can recharge cellular energy and improve vision health. We get into practical tips on using red light therapy—where to get it, when to use it, and what to watch out for in devices.

Learn more about Prof...

What happens when a UFC champion turns his focus from fighting in the cage to fighting aging? Former two-time UFC bantamweight champion TJ Dillashaw joins Nikki and Buck for a deep dive into stem cell therapy, peak performance, and biohacking longevity. TJ shares his experience with BioAccelerator’s advanced stem cell treatments, how they’ve impacted his injuries, and why he’s all-in on cutting-edge health optimization. From nutrit...

Emmy-winning writer and comedian Ed Crasnick joins Buck and Nikki to explore the connection between humor and health. From his work on Curb Your Enthusiasm to his passion for mental health advocacy, Ed shares how laughter reshapes our minds, reduces stress, and even boosts longevity. Plus, Nikki and Buck dive into Reddit’s latest medical misadventure and share their personal experiences with stem cell therapy.

Learn more about E...

Join Buck and Nikki as they dive headfirst into the future of regenerative medicine. In this episode, they’re in Medellín, Colombia, where they didn’t just explore cutting-edge stem cell therapy at BioXcellerator—they experienced it themselves. Alongside CEO Eric Stoffers, they uncover how these groundbreaking treatments are transforming lives, from autoimmune diseases to orthopedic challenges and beyond. Hear their personal storie...

Can a sense of purpose truly extend your life? In this episode of Longevity Junky, Buck and Nikki sit down with renowned psychologist Dr. Michael Mantz to explore the powerful connection between purpose, health, and longevity. Discover how finding meaning in life can rewire your brain, boost your vitality, and unlock the secrets to living longer and healthier.

Learn more about Dr Michael Mantz:

https://x.com/michaelmantzmd

Que...

Get ready to explore the cutting-edge science (and a little skepticism!) on all things longevity. In this episode, Nikki and Buck welcome Dr. Charles Brenner—a world-renowned expert on NAD biology and vocal critic of exaggerated longevity claims. Together, they unpack the hype versus the hard science behind aging, healthspan, and the latest buzz around supplements like NAD precursors. This unfiltered conversation blends fascinating...

Is your gut the secret to a longer, healthier life? Join Buck and Nikki as they sit down with Dr. Steven Gundry, renowned cardiologist and best-selling author, to uncover the fascinating link between gut health, chronic inflammation, and longevity. From reversing autoimmune diseases to revealing why olive oil might just be your health MVP, this episode dives deep into groundbreaking insights and practical tips. Don’t miss this gut-...

We are back with part two of our holiday special, where Buck Joffrey and Nikki Leigh dive into transformative moments from 2024. From Nikki’s raw and revelatory ayahuasca experience to groundbreaking insights on ketamine as a life-changing therapy, this episode explores healing, hope, and the science of overcoming trauma. Plus, laugh-out-loud moments with Dr. Ashley Winter on sexual health and how stem cells might finally be able t...