Concentrating on Chromatography
Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!
Episodes
How do the hidden carbohydrate structures on your favorite protein powders shape the gut microbiome? In this episode of Concentrating on Chromatography, Matthew Bolino, M.S., from the University of Nevada, Reno, breaks down his latest research on N‑glycans from common dietary proteins (whey, egg white, soy, and pea) and how their structural diversity influences microbial fermentation and short‑chain fatty acid production.Bolino exp...
In this episode, we interview Daniel Reddy, 2025 CAS Future Leader and PhD candidate at Queen's University, about his groundbreaking research on automated mass spectrometry and dried matrix spots (DMS).Dan's work combines computer vision, 3D printer automation, and laser micromachining to revolutionize sample preparation—reducing CO₂ emissions by 28-fold and organic solvent use by 21-fold compared to traditional methods.Wha...
Join us as we sit down with Jim Gearing, Associate Vice President of Marketing for Agilent's Gas Phase Division, to explore how the world of chromatography is changing and how intelligent instrument design is meeting users where they are.This interview was conducted in collaboration with Separation Science, the premier online learning platform for analytical scientists, providing expert content on chromatography, mass spectrome...
In this episode of Concentrating on Chromatography, we sit down with Dr. Lee Polite from Axion Training Institute to break down one of analytical chemistry's most powerful yet misunderstood techniques: gas chromatography-mass spectrometry (GC/MS).What You'll Learn:- Why GC and MS are the "perfect pair" – and what happens when you try to use MS alone- The electron gun: how molecules get ionized and why they become ...
Connor Johnson, a researcher from the University of Alberta, discusses his award-winning honours project analyzing the volatile organic compounds (VOCs) in two banana species using headspace gas chromatography-mass spectrometry (HS-GC-MS). He completed this specific project as an undergraduate at Thompson Rivers University (TRU).For over 60 years, commercial banana flavoring has remained unchanged—even though the fruit it's sup...
Join us for an in-depth conversation with Holly Lee, Global Technical Marketing Specialist at SCIEX, as we explore the cutting edge of food and environmental safety testing. Holly shares her expertise on analyzing ultra-short chain PFAS like TFA, masked mycotoxins, pesticide residues, and the latest LC-MS/MS workflows transforming laboratory efficiency.In this episode of Concentrating on Chromatography, we discuss:PFAS Analysis &am...
In this episode of Concentrating on Chromatography, we sit down with Alex Brody, an organic chemist at Aqua America, to discuss the rigorous analytical methods required for regulated drinking water testing.Alex walks us through the multi-step PFAS detection process using EPA Method 537.1, including extraction, nitrogen blowdown concentration, and LC-MS analysis. He explains why sample preparation and quality control are critical fo...
In this episode of Concentrating on Chromatography, we sit down with Andreas Metousis, a PhD researcher at the Max Planck Institute of Biochemistry, to explore cutting-edge spatial proteomics and its role in understanding ovarian cancer development.Andreas discusses how Deep Visual Proteomics (DVP)—a method combining artificial intelligence, laser micro-dissection, and advanced mass spectrometry—is revolutionizing cancer research b...
In this episode of Concentrating on Chromatography, David interviews his former high school chemistry teacher, Dr. Kristen Vanderveen from The Bromfield School, about teaching separation science at the high school level.Dr. Vanderveen shares her approach to introducing chromatography, filtration, and gravimetric analysis to both first-year chemistry students and AP Chemistry students. She discusses the hands-on experiments that wor...
Join host David Oliva from Organomation for an in-depth conversation with Sean Orlowicz, Principal Marketing Development Manager at Phenomenex, about the analytical challenges and innovative solutions for GLP-1 peptide therapeutics like semaglutide and tirzepatide.In this episode, presented in collaboration with Separation Science (https://www.sepscience.com/)—a premier learning platform for analytical scientists—Sean shares over 2...
Join us for an insightful conversation with Dr. Ryland Giebelhaus a chromatographer and metabolomics researcher from the University of Victoria, as he breaks down fecal microbiota transplantation (FMT)—a revolutionary treatment changing lives by restoring healthy gut bacteria. In this episode, you’ll learn:- What FMT is and why it’s a game-changer for treating recurrent Clostridioides difficile infections and other gut-related dise...
Join us in this fascinating episode of Concentrating on Chromatography as Dr. Rachael Guenter, PhD, shares her eight-year journey researching neuroendocrine tumors. Discover how her background in plant pathology and engineering shaped her translational medicine approach, and learn about the crucial role of mass spectrometry in uncovering protein-level insights in these rare cancers. Dr. Guenter also discusses the challenges of tran...
Join analytical chemist Dr. M. Farooq Wahab from the University of Texas at Arlington as he breaks down the science behind chromatographic peak shapes in this episode of the Concentrating on Chromatography podcast. Perfect for undergraduate chemists and researchers alike, this conversation covers:- What makes an ideal chromatographic peak shape and why it matters - Common reasons your HPLC peaks might show tailing, fronting, or dis...
Join us for an insightful conversation with Pernilla Sörme, Technical Program Director at My Green Lab, as we explore how one organization is transforming laboratories worldwide into leaders in environmental sustainability. Discover the driving mission behind My Green Lab, the measurable impact on research and industry, and real-world tips for saving energy and reducing plastic waste in scientific labs. Pernilla shares how behavior...
In this episode of the Concentrating on Chromatography podcast, host David Oliva interviews Ainslie Chen about her cutting-edge research on hemoglobin variant testing using liquid chromatography-high resolution mass spectrometry (LC-HR-MS). Ainslie discusses her novel method for separating and identifying hemoglobin subunits with mass shifts less than 1 Da, overcoming critical limitations in conventional clinical assays.Hear firsth...
Join us for a fascinating conversation with Dr. Subhoja Chakraborty from the University of Central Florida, whose cutting-edge research targets the global challenge of malaria drug resistance. Dr. Chakraborty shares her journey from structure-based drug design during her PhD to her recent collaborative work repurposing human kinase inhibitors as rapid, selective antimalarials against drug-resistant Plasmodium falciparum strains.In ...
In this special episode of Concentrating on Chromatography, host David Oliva steps into the guest role to share his journey as featured on the Lab Matters podcast. David discusses his transition from a passion for business and economics to leading Organomation, a renowned manufacturer of laboratory instrumentation and sample preparation tools. Organomation's flagship products—like the N-EVAP, MULTIVAP, and MICROVAP nitrogen eva...
Join us for an exciting deep dive with Isaac Plutzer, a graduate researcher at Washington University in St. Louis, as he explores the mysterious "dark kinome"—the hundreds of under-studied protein kinases with high potential for therapeutic discovery. In this interview, Isaac explains what kinases are and why a substantial fraction remain enigmatic, despite being critical regulators of cellular processes.
Isaac shares how ...
Join Dr. Guy Caldwell, Distinguished Research Professor at the University of Alabama, for a riveting and urgent conversation that goes beyond the lab bench to the heart of America’s biomedical research crisis. In this episode, Dr. Caldwell—an internationally recognized leader in neurodegenerative disease research—shares the real-world impact of NIH funding freezes, budget cuts, and policy gridlock on labs, promising young scientist...
Join us for a fascinating conversation with Dr. Chad Pozarycki, PhD in analytical chemistry and astrobiology, as we dive into the cutting-edge science behind searching for life beyond Earth. In this episode, we explore groundbreaking research on how biosignature molecules—such as amino acids and ATP—can accumulate and persist in extreme, hypersaline brine environments analogous to those found on Mars, Europa, and other planets.Dr. ...
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