What's Up Docs?

What's Up Docs?

In this BBC Radio 4 podcast, Drs Chris and Xand van Tulleken are on a mission to help us take better care of ourselves. Although they are identical twins, Chris and Xand are very different and they never stop thinking and arguing about science and health. They want to lead healthy, happy lives and as doctors, they want this for everyone. Yet they tussle over how best to get there. When it comes to looking after our own health, it can be confusing. Medicine and science produce amazing new treatments and diagnostics every day and we are bombarded with so many headlines and pieces of advice; but how are we supposed to know what's really best for us and then successfully apply it to our lives? Drs Chris and Xand van Tulleken embrace this challenge; even as they marvel at the scientific breakthroughs, they grapple with the competing claims about health, wellbeing and how to live. From understanding testosterone therapies to microplastics in our diets, and the concept of 'hangriness' to the power of saying no - this podcast deals with the health stresses we all face every day, while taking on board how the decisions by corporations and governments affect all our health. Each episode, Chris and Xand are joined by an expert guest to examine the latest research, psychological insights, and data, to help listeners navigate the overwhelming amount of information and advice out there. They talk about the trials and tribulations in their own lives in their characteristically witty way - each teasing the other as they search for solutions. Xand has trouble sleeping , Chris has noisy knees, one of them has got an embarrassing itch. They have different ways of looking at things and find it really helpful to get the other one's point of view. These doctors are trying their best and encouraging listeners to do the same. Email: whatsupdocs@bbc.co.uk Whatsapp: 08000 665123 A Loftus Media production for BBC Radio 4.

Episodes

July 14, 2026 20 mins

Chris and Xand continue their conversation about AI medicine with Dr Emma Karoune.

The docs explore how AI has been used in cutting edge medical research, such as to create digital models of the heart to enable instant alerts to a doctor. They want to know about AI for pattern recognition and how this can be used in determining changes in scans or predicting pandemic. They also want to know more about how ambient AI can be useful to...

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Welcome to What’s Up Docs?, the podcast where identical twin doctors Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.

Can AI empower better self-care and clinical practice, or is it just more health noise? Most of us have fallen down a search engine rabbit hole only to emerge more confused about our symptoms than when we started. But as we enter the era of Large Language Mo...

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In this extended episode of What's Up Docs?, Chris and Xand van Tulleken continue their conversation with Professor Robin Condliffe.

Together, they explore how our understanding of the lungs has evolved over time, from early theories about breathing to the breakthroughs that transformed modern respiratory medicine.

They also examine why lung health is shaped by more than biology alone. From air pollution and housing quality to povert...

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Welcome to What's Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken explore the ideas shaping our health and wellbeing.

In this episode, recorded live at Crossed Wires Festival in Sheffield, they are joined by Professor Robin Condliffe, Consultant Respiratory Physician at Royal Hallamshire Hospital.

Together, they explore the extraordinary science of the lungs: how they work, how they keep us alive, ...

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June 30, 2026 21 mins

Chris and Xand van Tulleken take a deeper dive into heart palpitations and the rise of wearable technology.

With devices like smartwatches now able to detect irregular heart rhythms, more people are being alerted to potential problems, often without any symptoms. But is this early detection saving lives, or creating new challenges?

Joined again by Consultant Cardiologist Dr Pranev Sharma, the docs explore how wearables actually work,...

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Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken explore the ideas shaping our health and wellbeing.

In this episode, they turn their attention to heart palpitations. That sudden flutter, skipped beat or racing heart can feel alarming, but what’s actually going on, and when should you be concerned?

They break down what palpitations are, what causes them, and what’...

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June 23, 2026 30 mins

Chris and Xand continue their conversation about body odour with Matthew Cobb, Professor Emeritus of Zoology at the University of Manchester.

They explore whether it’s possible to predict how someone experiences an odour based on their DNA, and how our sense of smell compares to that of other animals.

Many people lost their sense of smell during the Covid-19 pandemic, bringing greater awareness to just how central this sense is...

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Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken explore the ideas shaping our health and wellbeing. In this episode, they explore something that affects every one of us - body odour.

Body odour plays a significant role in our emotional and social lives, and even in our health. Chris and Xand explore what body odour actually is, where it comes from, and why it varies so muc...

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This extended episode of What's Up Docs? features Chris and Xand van Tulleken's full live conversation with Professor Devi Sridhar at Hay Festival.

Going deeper than the main episode, they explore the tension between individual responsibility and structural change, and why asking "how do I stay healthy?" might be the wrong question altogether. Devi draws on her work across governments and health systems worldwide to examine what gen...

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June 16, 2026 28 mins

Welcome to What's Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken explore the ideas shaping our health and wellbeing.

In this episode, recorded live at Hay Festival, they're joined by Professor Devi Sridhar, Chair of Global Public Health at the University of Edinburgh, to ask how we can live longer, healthier lives.

They dig into the difference between life expectancy and healthy life expectancy, ...

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June 9, 2026 22 mins

Chris and Xand van Tulleken continue their conversation about friendship with Dr Tiffany Watt Smith, writer and culture historian.

Tiffany became interested in researching friendships after a moment of crisis in her own friendships. Together, Chris, Xand and Tiffany discuss the difference between male and female friendships and how that has changed over time. They explore the idea that we are living through a friendship recession an...

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June 9, 2026 28 mins

Welcome to What’s Up Docs?, the podcast where identical twin doctors Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.

In this episode, the Docs take a look at the impact our friendships have on our physical health. Why different friendship styles are important and how we can maintain and nurture our social connections.

Joining them is Dr Tiffany Watt Smith, a writer and cul...

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June 2, 2026 17 mins

Chris and Xand van Tulleken take a deeper dive into male contraception with Professor Richard Anderson.

They explore why, despite decades of research, new male contraceptive options are still limited. From funding gaps to shifting attitudes, they unpack the social and scientific barriers that have shaped progress so far.

They also look at how people feel about the idea of male contraception, whether those attitudes are changing, and ...

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Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken explore the ideas shaping our health and wellbeing.

In this episode, they turn their attention to male contraception. We’ve been hearing about a “male pill” for decades, so why don’t we have one yet? They break down how male fertility works, what options currently exist, and the different approaches sci...

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May 26, 2026 14 mins

Chris and Xand continue their conversation about the lymphatic system with Professor Kristiana Gordon, a Consultant in Dermatology and Lymphovascular Medicine.

The docs ask about the growing field of lymphoedema research and how our understanding of the lymphatic system has developed in recent years. They also explore primary lymphoedema, a condition caused by genetic errors that can affect children and young people, and ask what ad...

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Welcome to What’s Up Docs?, the podcast where identical twin doctors Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.

In this episode, Chris and Xand explore the lymphatic system, from its vital everyday functions supporting fluid balance and immunity to its more mysterious roles. They look at what happens when things go wrong, examine popular wellness claims around drainin...

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May 19, 2026 21 mins

In this Doctors' Notes episode of What’s Up Docs?, Chris and Xand van Tulleken take a deeper dive into hay fever with Professor Stephen Till.

The docs and their guest explore whether hay fever is really becoming more common, and if so, why. From climate change and air pollution to changes in our environment and biodiversity, they unpack the factors that may be making symptoms worse. They also look at how hay fever varies aroun...

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May 19, 2026 28 mins

Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken explore the ideas shaping our health and wellbeing.

In this episode, they turn their attention to hay fever. What is it, why do so many of us get it, and is it getting worse? They break down what’s happening in the body, how to tell it apart from a cold, and why timing matters when it comes to treatment. They also explor...

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May 12, 2026 20 mins

Chris and Xand continue their conversation about calcium with Dr Sagen Zac-Varghese.

The docs want to know about common issues that are seen around calcium and bone health, especially osteoporosis. They want to learn how osteoporosis relates to calcium, who is at risk and why it is more common in women. They also want to know what inspired Sagen’s passion for calcium and what we can learn from astronauts about bone health.

If y...

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May 12, 2026 28 mins

Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.

In this episode, Chris and Xand dive into calcium. What is calcium, and what does it do in the body? How important is it for our health? How do we maintain healthy levels of calcium? They also examine how calcium interacts with vitamin D, whether we nee...

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