Big Picture Science

Big Picture Science

The surprising connections in science and technology that give you the Big Picture. Astronomer Seth Shostak and science journalist Molly Bentley are joined each week by leading researchers, techies, and journalists to provide a smart and humorous take on science. Our regular "Skeptic Check" episodes cast a critical eye on pseudoscience.

Episodes

Amazing Amazonia

December 1, 2025 • 73 mins
The Amazon is often described as an ecosystem under dire threat due to climate change and deliberate deforestation. Yet there is still considerable hope that these threats can be mitigated.  In the face of these threats, indigenous conservationists are attempting to strike a balance between tradition and preserving Amazonia.  Meanwhile, two river journeys more than 100 years apart – one by a contemporary National Geographic reporte...
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Flu the Coop

November 24, 2025 • 64 mins
The worry about whether H5N1 will trigger a human pandemic has concealed a startling reality. Avian influenza has already taken an enormous toll on the lives of other animals. Since 2005, the number of wild and domesticated birds killed is greater than the combined human populations of the United States and Russia. Bird flu is burning through wild flocks, poultry farms, and mammal populations, including those of sea mammals. We loo...
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Skeptic Check: String Theory

November 17, 2025 • 54 mins
The idea that the universe is made of tiny vibrating strings was once the science theory du jour. String theory promised to unite the disparate theories describing particles and gravity, and many people, not just scientists, were optimistic that a theory of everything might be within our grasp. But here we are, many years later, and string theory doesn’t seem to have delivered on its initial promise. What happened? We consider the ...
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Solar Good

November 10, 2025 • 58 mins
In Brazil, leaders from across the globe are gathering for COP30, the premier climate summit in the world. For the first time, the U.S. is sitting it out, after exiting the Paris Agreement. There is, however, a ray of hope in the global efforts to reduce fossil fuel emissions. Bill McKibben, an environmentalist and journalist who describes himself as a “professional bummer-out-of-people,” has good news about the solar energy indust...
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Katrina and the River

November 3, 2025 • 67 mins
“The Mississippi River will always have its own way; no engineering skill can persuade it to do otherwise,” said Mark Twain. In this, our final episode marking the 20th anniversary of Hurricane Katrina, we consider how efforts to control the Mighty Mississippi – a river engineered from its Minnesota headwaters to its Gulf Coast outlet – have responded to the devastating storm, and how New Orleans’ relationship to the river has chan...
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The Decomposers

October 27, 2025 • 56 mins
What happens to us after we die is as much a question for anthropology and ecology as it is for theology.  Death and decay are not comfortable subjects, but some scientists study them unflinchingly, knowing that doing so yields valuable scientific insights about decomposition. We hear about The Body Farm at the University of Tennessee, Knoxville where forensic anthropologists dissect how variables, such as weather and insects, affe...
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Shipwrecks

October 20, 2025 • 54 mins
Shipwrecks are scenes of tragedy, but they are also bits of history frozen in time that can provide insights into events and ideas from long ago. That is, if we can find them.  From an 11th century Viking sailing ship to a WW II era British cargo ship with a mailbag of letters onboard amazingly preserved, an underwater archeologist takes us on a deep dive into history. Guest: David Gibbins - underwater archeologist, novelist, and...
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Mad About Mars

October 13, 2025 • 56 mins
Long before Orson Welles provoked a panic with his 1938 radio broadcast of a Martian invasion in War of the Worlds, we were fascinated with the possibility of life on the Red Planet. We may be a step closer to finding it after the Perseverance rover turned up tantalizing evidence of possible ancient life in the form of mineral deposits in a Martian rock. But to be sure, we need to test that rock sample in a lab here on Earth, and t...
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Skeptic Check: Health Fads

October 6, 2025 • 54 mins
The tiny bean-shaped structures in your cells – mitochondria – are little powerhouses. Recent research suggests they may unlock overall good health, or, when they fail, cause diseases such as diabetes and Alzheimer’s. How strong is the science for these claims and what, if anything, should we be doing to improve our mitochondrial health? Should we take a cue from influencers who suggest drinking an industrial dye called methylene b...
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Not Just a Phage

September 29, 2025 • 54 mins
We’re hurtling towards a post-antibiotic world, as the overuse of antibiotics has given rise to dangerous drug-resistant bacteria. Can we fight back using viruses as weapons? An obscure medical therapy uses certain viruses called bacteriophages to treat infection. For a century attempts to turn phage-therapy into a life-saving treatment have faltered, but today there’s renewed interest in this approach. Can we use phages to foresta...
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Spare (Body) Parts

September 22, 2025 • 54 mins
Strapped-on brass noses, frog skin grafts, human organs grown in pigs: The world of replaceable body parts is both amazing and a bit unsettling. But who better give us a tour of the past and present of what medical engineering considers Plan B, than the inimitable science writer Mary Roach. Guest: Mary Roach – Science writer and author of “Replaceable You: Adventures in Human Anatomy” Featuring music by Dewey Dellay and Jun Miya...
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Some Chemicals are Forever

September 15, 2025 • 57 mins
As their name suggests, “forever chemicals” have extraordinary staying power. When these nearly indestructible compounds find their way into our soil and water, they don’t break down for hundreds or thousands of years. PFAS – the name for these synthetic chemicals – isn’t just in our natural environment. Scientists have found it everywhere, including in the blood of nearly every living being.  In this episode, we talk to the repor...
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Animal Alphabets

September 8, 2025 • 54 mins
Have scientists discovered an alphabet in whale calls? As researchers try to decipher the series of clicks made by sperm whales, we ask whether these cetaceans might have language, and if it follows that whales are thinking animals too. Could we one day get a peek into the thoughts of a humpback whale? Meanwhile, somewhere along the long path of evolution, one species emerged with an impressive gift for gab. Are speech and language...
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Aliens Now

September 1, 2025 • 54 mins
We are closer than ever to finding aliens according to astrophysicist Adam Frank. He isn’t alone in his optimism. Over the last two decades, the tools used to search for extraterrestrials have been advancing mightily. Where we were once only monitoring with radio telescopes, we are now actively looking for bio and technosignatures on exoplanets. Find out why scientists think new technology may be a game changer in the hunt for life...
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Don't Lighten Up

August 25, 2025 • 54 mins
A canopy of stars in the night sky is more than breathtaking. Starlight is also an important tool that astronomers use to study our universe. But the growth of artificial light and light pollution are creating dramatic changes to the nighttime environment. Let your eyes adjust to the dark as we travel to a dark sky reserve to gaze upon an increasingly rare view of the Milky Way and explore what we lose when darkness disappears.   ...
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Katrina and the River

August 18, 2025 • 65 mins
“The Mississippi River will always have its own way; no engineering skill can persuade it to do otherwise,” said Mark Twain. In this, our final episode marking the 20th anniversary of Hurricane Katrina, we consider how efforts to control the Mighty Mississippi – a river engineered from its Minnesota headwaters to its Gulf Coast outlet – have responded to the devastating storm, and how New Orleans’ relationship to the river has chan...
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Beyond the Standard Model

August 11, 2025 • 59 mins
Ever heard of a beauty quark? How about a glueball? Physics is full of weird particles that leave many of us scratching our heads. But these tiny particles make up everything in the quantum world and in us and are the basis of the fundamental scientific theory called The Standard Model. But it doesn’t explain everything. It can’t account for dark matter or dark energy, for example. We find out whether new physics experiments might ...
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Scoping Out the Universe

August 4, 2025 • 54 mins
Telescopes are like light buckets. The bigger the telescope, the more light collected for astronomers to observe. With recent advances in technology, amateur astronomers can join professionals for a chance to observe stellar nurseries and exoplanets many light-years away. But as our capabilities increase, so do the mysteries, including those around high-energy bursts coming from an otherwise unremarkable part of the universe. Under...
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Leave it to Beavers

July 28, 2025 • 58 mins
They are known for holding branches in their paws and gnawing on them like corn cobs. They build lodges and dams which occasionally flood roads. Cute, comical, and considered pests, beavers were nearly hunted to extinction for their pelts before conservation efforts allowed their populations to rebound. Now environmentalists and engineers are reintroducing North America’s largest rodent to drought-prone habitats across the country....
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The Play's the Thing

July 21, 2025 • 59 mins
Has children’s play become too safe? Research suggests that efforts to prioritize safety harms children’s mental and physical development during play and contribute to anxiety. One solution: introduce risk into play. We visit an adventure playground where kids play unsupervised with anything from scraps of metal to hammers and nails. Plus, what are the evolutionary benefits of play? After all, we’re not the only species who like to...
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