Probably Science

Probably Science

Professional comedians with so-so STEM pedigrees take you through this week in science. Incompetently. Featuring hosts Matt Kirshen, Andy Wood (and sometimes Jesse Case or Brooks Wheelan) along with a rotating cast of special guests from the worlds of comedy and science.

Episodes

January 13, 2026 74 mins
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December 28, 2025 70 mins
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November 28, 2025 84 mins
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November 14, 2025 72 mins

Comedian Jess Zenisek (@jeffzenisek) joins Andy, Jesse and Matt to talk about tennis, homophobic sports stereotypes, Jesse's new ski persona, Mr. Wizard, Jeff's hair care regimen, a tiny tyrannosaur, a better rock-paper-scissors strategy, gray hair's relationship to cancer, the worst music to play during sex and the banger Parked By The Lake.

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November 9, 2025 51 mins

Comedian/playwright Drew Droege (@drew_droege) joins Matt, Jesse and Andy to talk about his new off-Broadway play Messy White Gays, X-ray NBA poker fraud and why birds sing after a solar eclipse.

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October 29, 2025 53 mins

Wonderful NY comic Mehran Khagani (@themehran) joins Jesse and Matt to talk about escaping from Iran, working at the Harvard School of Public Health, hyrax  butt drag fossil marks, Canadian  heart transplants and the  most pristine star in the universe!

In the patreon bonus we get into penguin micronaps.

Click here to support Probably Science via Patreon

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NASA astrophysicist and JPL Exoplanet Science Ambassador Anjali Tripathi joins Andy, Jesse and Matt to talk about exoplanets and the different ways of finding them including radial velocity, transits and gravitational microlensing, the challenges of studying planetary atmospheres, why telescopes are built in deserts or in space, Anjali's time at the White House Office of Science and Technology Policy, science communication projects...

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September 26, 2025 81 mins
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September 8, 2025 71 mins
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August 28, 2025 71 mins

Comedian Myq Kaplan (@myqkaplan) returns to the show to talk to Andy, Jesse and Matt about growing out his eyebrows during the pandemic, babies distinguishing Ps from Bs, linguistics, sign language variations, standups aping Shane Gillis, the Mr. Beast voice, birds' preference for crapping in the air, strong link versus weak link problems, Ryan North, whether you should pay for bad art, what sequels always get wrong and Myq's great...

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August 20, 2025 61 mins

Comedian and host of the SSRI'M OK podcast Macey Isaacs joins the gang to talk about a meteorite that's older than our planet! AI and attachment theory! And some more AI nonsense before Andy's connection quit in a fury!

In the Patreon bonus we find out why living near the ocean extends your life.

Follow Macey on instagram and check out her podcast, and her Don't Tell speci...

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July 25, 2025 69 mins

Comedian Kai Humphries (@kaihumphries) joins Matt, Andy and Jesse to talk about his new special Gallivanting, the passing of Hulk Hogan, superheating solid gold, the Air Bud cinematic universe and an enormous 80,000-year-old blob in Utah.

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July 21, 2025 71 mins

Comedian Eric Rocha (@ericrochacomedy) joins Andy, Jesse and Matt to talk about competing namesakes, fezzes, last suppers, Jesse's macronutrient gas, sleep hygiene, comedy on airplanes, what would happen if you threw a paper airplane from the ISS, a neanderthal fat factory, Matt's standup tour and Andy's Colorado ska tour.

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