Core IM | Internal Medicine Podcast
Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges
Episodes
Who’s really at risk for fractures, and how should we be treating them?
Most fragility fractures occur in patients without osteoporosis. Should we rethink who gets treated? And could just one or two IV infusions (spread years apart) of zoledronate prevent fractures for years? Have the concerns about bisphosphonates been overblown?
Find out all the nuances on this episode of Beyond Journal Club, a series brought to you by Core IM in ...
Medications for orthostatic hypotension! When to initiate treatment, how to use them safely, and what to do when new issues arise during treatment. How do those change if someone has autonomic failure? What do you do when your patient has hypertension AND also has orthostatic hypotension?
🔹 Sponsor: Oakstone CME’
Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP
Timestamps ...
Learn specific, practical ways to counsel patients on non-pharmacologic interventions. What is our goal with OH treatment? Is it the blood pressure number that matters? How do we avoid missing neurogenic causes of orthostatic hypotension (OH)?
🔹 Sponsor: Oakstone CME’
Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP
Timestamps:
(00:05) | Case Presentation: Urinary Retention ...
Next time you’re squinting at a chest tube, feel confident you know exactly what to look for and why. Hear it explained in a way that really sticks!
🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion
Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP
Timestamps:
(02:50) | Xray vs. POCUS vs. CT for Pneumothorax Diagnosis
(07:29) | Do All PTXs Need Chest Tubes?
(11:55) | Explainin...
How do you work up neutropenia? When is neutropenia benign? When do neutrophils recover? How can you diagnose neutropenic fever in the first 15 minutes and start antibiotics in the first 60 minutes? Do you always add MRSA coverages? Only Pseudomonas coverage? When do you add fungal coverage?
🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion
Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP
Have a good laugh and reflect deeply with these three stories that hit the feels in different ways.
If you'd love to hear more stories from Dr. Maria Rosasco, check out some of her other appearances on the podcast: July Stories and Handoffs & Contingency Planning.
🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion
Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP
What went wrong? What were the reasoning or contextual missteps that led us astray?
🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply! Due Aug 1, 2025
🔹 Transcript and Show Notes
Timestamps:
(00:02) | Case Presentation and Initial Diagnosis
(02:47) | Tachycardia and Early Impressions
(04:10) | Clinical Deterioration and New Clues
(07:19) | Problem Representation and Reflection
(21:45) | Lessons on Reasoning and Bi...
- Imaging Pearls | (01:12)
- Deciding on Thoracentesis | (04:00)
- Light’s Criteria and Pseudoexudates | (07:00)
- Pleural Fluid Studies: pH and Cell Differential | (16:56)
- Diagnosing and Treating Parapneumonic Effusions | (23:32)
- Malignant Pleural Effusions: Diagnosis and Management | (30:39)
🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion
Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP
Listen for some good laughs and relatable stories!
In this episode, we share raw and real stories from July — from rapid responses to unexpected kindness — and reflect on the emotional weight of starting out in medicine.
🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply! Due Aug 1, 2025
Prior July Stories:
July Stories 2.0 (2023)
July Stories (2019)
Timestamps:
(00:32) | Dr. Ali Trainor...
How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and explore the REDUCE-AMI trial, which questions whether beta blockers are still needed for all.
Listen to this latest episode of Beyond Journal Club, a collaboration between Core IM and NEJM Group, where we put research into context tracing ...
🔹 What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46)
🔹 What are the main classes of fungi? (~11:35)
🔹 What are the pros and cons of B-D Glucan and Galactomannan (~19:16)
🔹 How to increase the yield of blood cultures? How to interpret yeast growth in sputum/BAL and urine cultures? (~ 30:42)
🔹 How is invasive fu...
🔹What are clinically relevant limitations of an A1c vs. a CGM (1:40)
🔹What do the different parts of the ambulatory glucose profile tell you? (09:59)
🔹What are common pitfalls, medications, lifestyle patterns that are important to ask your patient about when seeing them for a visit to manage blood sugar? (15:19)
🔹 How can you titrate insulin based on when you see the hypoglycemia on the ambulatory glucose profile (20:00)
🔹 When th...
🔹When is an U/S vs. CT vs. MRI helpful before consulting Interventional Radiology?
🔹What factors go into an IR pre-op evaluation?
🔹 When do drains go in, and when do they come out?
🔹 When a patient has trouble with a drain, what are things you can do before calling IR?
🔹 What does outpatient IR follow up entail, and what does a capping trial of PCN tubes entail?
📌 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion
🔹 High-yield reversible causes of constipation? (02:26)
🔹 Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03)
🔹 Osmotic vs Stimulant Laxatives (15:06)
🔹 Suppositories and enemas? (25:39)
🔹Best practices with opioid induced constipation (34:05)
📌 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is H...
How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables, and then to the PURPOSE trials, which look at the use of long-acting lenacapavir as PrEP — a potential game-changer in the field of HIV.
Listen to this latest episode of Beyond Journal Club, a collaboration between CoreIM and NEJM Group, where we put research into context, tell...
What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to interpret results, counsel patients, and navigate topics with limited data like aspirin and PCSK9 inhibitors in treatment.
🔹 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learn...
A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and practical approaches!
🔹 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant!
What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes?
Join us as we tackle these questions and discuss the APAChE study on microplastics and cardiovascular disease on this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.
What is the last sense to go? How can music create connection, ease anxiety, and help process emotions at the end of life? Join Dr. Jafar Al-Mondhiry, Dr. Harry Han, and music therapist Bryanna Tobin as they explore the power of music therapy in hospice care, sharing moving stories and clinical insights.
🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a ...
Incidental fibrosis on CT —what now? What does prone imaging tell you? Is it fibrosis, aspiration, or atelectasis? And once you diagnose ILD, does the “alphabet soup” really matter for treatment? Antifibrotics vs. immunosuppression?
Plus, how do we bridge the gap when social barriers make care unsafe?
🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a spec...
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