Practical AI

Practical AI

Making artificial intelligence practical, productive & accessible to everyone. Practical AI is a show in which technology professionals, business people, students, enthusiasts, and expert guests engage in lively discussions about Artificial Intelligence and related topics (Machine Learning, Deep Learning, Neural Networks, GANs, MLOps, AIOps, LLMs & more). The focus is on productive implementations and real-world scenarios that are accessible to everyone. If you want to keep up with the latest advances in AI, while keeping one foot in the real world, then this is the show for you!

Episodes

June 18, 2025 41 mins

It seems like we are bombarded by news about millions of dollars pouring into AI startups, which have crazy valuations. In this episode, Chris and Dan dive deep into the highs, lows, and hard choices behind funding an AI startup. They explore early bootstrapping, the transition to venture capital, and what it’s like to trade in code commits for investor decks. 

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An recent article in Variety was titled: "Sylvester Stallone-Backed Largo.ai Teams With Brilliant Pictures for ‘World’s First Fully AI-Automated Film Company’". Obviously this caught our attention! We sit down with Sami Arpa, CEO of Largo.ai, to unpack how films are developed, funded, and brought to life using AI. We discover how tools like script analysis, financial forecasting, and digital twins are helping creators and ...

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Chong Shen from Flower Labs joins us to discuss what it really takes to build production-ready federated learning systems that work across data silos. We talk about the Flower framework and it's architecture (supernodes, superlinks, etc.), and what makes it both "friendly" and ready for real enterprise environments. We also  explore how the generative Generative AI boom is reshaping Flower’s roadmap.

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  • Chong She...
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In this first of a two part series of episodes on federated learning, we dive into the evolving world of federated learning and distributed AI frameworks with Patrick Foley from Intel. We explore how frameworks like OpenFL and Flower are enabling secure, collaborative model training across silos, especially in sensitive fields like healthcare. The conversation touches on real-world use cases, the challenges of distributed ...

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May 20, 2025 47 mins

Loïc Houssier, Head of Engineering at Superhuman, joins us to discuss how AI and LLMs are reshaping the email experience. He highlights challenges related to the variability of user prompts and infrastructure optimization. Loïc emphasizes that a deep focus on user experience and real human workflows is key to building AI tools people actually love to use.

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May 8, 2025 42 mins

In this episode, Daniel and Chris unpack the Model Context Protocol (MCP), a rising standard for enabling agentic AI interactions with external systems, APIs, and data sources. They explore how MCP supports interoperability, community contributions, and a rapidly developing ecosystem of AI integrations. The conversation also highlights some real-world tooling such as FastAPI-MCP.

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April 30, 2025 42 mins

In this episode, we explore the intersection of AI, machine learning, and healthcare through the lens of neuroimaging and epilepsy diagnosis. Dr. Gavin Winston shares insights from his work using MRI data and machine learning to uncover subtle abnormalities in brain function. We discuss the cultural and ethical barriers to AI adoption in medicine, how predictive data analysis could transform the diagnostic workflow, and wh...

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April 17, 2025 42 mins

Vibe coding, agentic workflows, and AI-assisted pull requests? In this episode, Daniel and Chris chat with Robert Brennan and Graham Neubig of All Hands AI about how AI is transforming software development—from senior engineer productivity to open source agents that address GitHub issues. They dive into trust, tooling, collaboration, and what it means to build software in the era of AI agents. Whether you're coding from yo...

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In this episode, Daniel sits down with Pavel Veller, EPAM’s Chief Technologist, to explore the practical challenges of orchestrating many AI agents and managing connections to disparate systems/tools. Pavel shares insights from his hands-on work with agentic architectures and internal tools like "DIAL". Pavel also helps us understand things like MCP servers and why connecting assistants via APIs is easy—but making them use...

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How do you enable AI acceleration (at both the hardware and software layers) that stays ahead of rapid industry shifts? In this episode, Dhananjay Singh from Groq dives into the evolving landscape of AI inference and acceleration. We explore how Groq optimizes the serving layer, adapts to industry shifts, and supports emerging model architectures. 

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March 21, 2025 50 mins

Kyle Daigle, COO of GitHub, joins the hosts to discuss the evolving role of AI in software development, GitHub Copilot’s impact, and the challenges of AI-assisted coding. The conversation covers licensing concerns, ethical considerations, and how developers can navigate these complexities. Kyle also shares his vision for ambient AI, which seamlessly integrates into workflows to enhance productivity and innovation, shaping ...

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We often judge AI models by leaderboard scores, but what if efficiency matters more? Kate Soule from IBM joins us to discuss how Granite AI is rethinking AI at the edge—breaking tasks into smaller, efficient components and co-designing models with hardware. She also shares why AI should prioritize efficiency frontiers over incremental benchmark gains and how seamless model routing can optimize performance. 

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  • Ka...
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March 8, 2025 47 mins

How can every single person build a personal AI protégé and then accumulate (and share) a host of other assistants? In this episode, we dive into the world of no-code AI with Scott Meyer from Chipp.ai. We discuss AI tooling for people that can't code, the cultural shift that needs to happen for widespread AI adoption in businesses, and the predicted growth trajectory of AI assistant that you can own.


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February 24, 2025 30 mins

It seems like all we hear about are the great use cases for GenAI, but where should you NOT be using the technology? On this episode Chris and Daniel share their hot takes and bad use cases. Some may surprise you!

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February 14, 2025 45 mins

It seems like everyone is uses the term “agent” differently these days. In this episode, Chris and Daniel dig into the details of tool calling and its connection to agents. They help clarify how LLMs can “talk to” and “interact with” other systems like databases, APIs, web apps, etc. Along the way they share related learning resources.

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January 31, 2025 50 mins

There is crazy hype and a lot of confusion related to DeepSeek’s latest model DeepSeek R1. The products provided by DeepSeek (their version of a ChatGPT-like app) has exploded in popularity. However, ties to China have raised privacy and geopolitical concerns. In this episode, Chris and Daniel cut through the hype to talk about the model, privacy implications, running DeepSeek models securely, and what this signals for ope...

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January 23, 2025 45 mins

We seem to be experiencing a surge of video generation tools, models, and applications. However, video generation models generally struggle with some basic physics, like realistic walking motion. This leaves some generated videos lacking true motion with disappointing, simplistic panning camera views. Genmo is focused on the motion side of video generation and has released some of the best open models. Paras joins us to di...

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December 19, 2024 53 mins

Daniel and Chris groove with Jeff Smith, Founder and CEO at CHRP.ai. Jeff describes how CHRP anonymously analyzes emotional wellness data, derived from employees’ music preferences, giving HR leaders actionable insights to improve productivity, retention, and overall morale. By monitoring key trends and identifying shifts in emotional health across teams, CHRP.ai enables proactive decisions to ensure employees feel support...

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December 11, 2024 51 mins

Today, Chris explores Shopify Magic and other AI offerings with Mike Tamir, Distinguished ML Engineer and Head of Machine Learning, and Matt Colyer, Director of Product Management for Sidekick. They talk about how Shopify uses generative AI and LLMs to enhance their products, and they take a deeper dive into Sidekick, a first-of-its-kind, AI-enabled commerce assistant that understands a merchant’s business (products, order...

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Kyutai, an open science research lab, made headlines over the summer when they released their real-time speech-to-speech AI assistant (beating OpenAI to market with their teased GPT-driven speech-to-speech functionality). Alex from Kyutai joins us in this episode to discuss the research lab, their recent Moshi models, and what might be coming next from the lab. Along the way we discuss small models and the AI ecosystem in ...

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