Unpacking Pain

Unpacking Pain

Unpacking Pain is a podcast about chronic pain - what causes it, how it affects our lives, and what we can do about it. Hosted by a pain scientist and a pain sufferer, it blends evidence-based science with lived experience to offer support, education, and empowerment. If you’ve ever felt unseen in your pain journey, know that you are not alone. Join us on Unpacking Pain as we peel back the layers of the chronic pain experience - where science meets story, and where knowledge opens doors to healing. Each week, Dr. Megan Steele, PT, DPT, PhD(c), and Holly Osborne, a chronic pain sufferer, sit down to explore the “three-legged stool” of chronic pain: the biological, psychological, and social. Together they demystify the science, share personal stories, and engage in candid conversations about the mind-body connection, treatment approaches, and the realities of living with and managing pain. What makes Unpacking Pain different is its unique yin-yang approach: Megan brings deep expertise in pain research and clinical practice, while Holly offers the raw honesty of 26 years of lived experience navigating chronic pain. Together, they create a space that is empathetic, candid, and enlightening. Topics include: - The neuroscience of pain and why it isn’t “all in your head” - Evidence-based pain management strategies that work in daily life - Practical strategies for coping and thriving with chronic pain - How stress, trauma, and emotions shape our pain journey - Stories of resilience, breakthroughs, and hope Whether you are living with chronic pain, supporting someone who is, or working as a health professional, this podcast offers insights that validate, educate, and inspire. Our goal is not just to explain chronic pain but to reframe it - making room for understanding, empowerment, and possibility. Your voice matters, we would love for you to send us your questions or share your story with us at unpackingpain@gmail.com. Together we can shed light on the realities of chronic pain, unpack the issues, and discover new ways forward. https://unpackingpainpodcast.com

Episodes

February 23, 2026 48 mins

Why do women make up 70% of chronic pain sufferers? The answer involves more than just biology. Dr. Megan and Holly examine how hormones, pain thresholds, and social conditioning create vastly different pain experiences for men and women.

You'll discover:

  1. Why pain thresholds change dramatically at puberty and menopause
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Why do two people with the same injury have completely different pain journeys - and what does a zip code have to do with it?

Today we dig into the often-overlooked social side of persistent pain: the way income, work conditions, food access, relationships, and even cultural expectations can ramp pain up or help dial it down.

Dr. Megan and Holly explore how:

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What if the pain you feel long after an injury has “healed” isn’t a sign that your body is broken, but that your nervous system is stuck in protection mode?

Dr. Megan and Holly break down what’s happening in the brain and body when pain lingers, scans look “normal,” and daily life starts to shrink. They explore how chronic pain and emotions are tightly linked, and why anxiety, depression, shame, and even hyper-empathy so often trave...

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February 2, 2026 52 mins

Why does chronic pain spread from one area of your body to another? And why does it often feel worse at night when you're trying to sleep?

When pain persists for months or years, your nervous system doesn't just stay the same - it changes. Your nerves lose their protective coating, your spinal cord becomes more sensitized, and your brain actually develops structural changes that keep you locked in a cycle of protection and threat de...

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February 2, 2026 12 mins

What happens when a pain researcher teams up with someone who’s lived with chronic pain for decades?

In this bonus conversation, meet the voices behind Unpacking Pain. Dr. Megan Steele, a physical therapist and pain science researcher, explains why evidence-based guidance is still hard to find and what the data actually says. Holly Osborne shares the lived experience side - what helped, what didn’t, and how to keep going when progre...

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February 2, 2026 35 mins

Why does a system designed to protect us sometimes keep the alarm blaring long after the danger has passed?

Chronic pain isn’t just about damaged tissue. Dr. Megan and Holly break down how the body’s warning system can stay on high alert and why understanding the biopsychosocial model - biology, psychology, and social context - can change the way you navigate persistent pain. You’ll hear clear examples, practical strategies, and a f...

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January 8, 2026 2 mins

What if chronic pain isn’t only a body problem, but a biology–psychology–social puzzle you can learn to solve?

Meet your guides: Dr. Megan Steele, a physical therapist and pain science researcher, and Holly, a long‑time pain experiencer with a thousand practical questions. Together, they break persistent pain into clear, human terms. You’ll hear candid stories, simple explanations of what’s happening in your brain and body, and smal...

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