Docs Who Lift

Docs Who Lift

Drs. Spencer and Karl Nadolsky talk about nutrition, medicine, and fitness through the lens of two physicians who lift weights. Both doctors are former NCAA division 1 wrestlers who have gone into medicine. Dr. Spencer Nadolsky is a board certified family physician specialized in obesity medicine and lipidology. Dr. Karl Nadolsky is a board certified endocrinologist also specialized in obesity medicine.

Episodes

August 22, 2025 33 mins

Takeaways

  • The podcast features Dr. Grant Tinsley, a body composition expert.
  • The discussion revolves around a case series on body composition effects.
  • GLP-1 receptor agonists are a focus of the research.
  • The importance of resistance training in weight loss is emphasized.
  • Patient case studies provide insights into individual experiences.
  • The first patient lost a significant amount of fat mass while preserving lean mass.
  • The second pati...
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Takeaways

Direct-to-consumer lab testing is on the rise, with significant marketing efforts behind it.

Many patients feel brushed off by traditional healthcare providers, leading them to seek alternative testing options.

Communication between patients and healthcare providers is often inadequate, contributing to misunderstandings about health.

Over-testing can lead to unnecessary anxiety and misinterpretation of results.

Fitness influen...

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August 8, 2025 20 mins

In this episode of the Dr. Lift podcast, hosts Dr. Spencer Nadolsky and Dr. Karl discuss the recent changes in obesity medication coverage, particularly focusing on the CVS Caremark decision to drop ZEPBound from their formulary in favor of Wegovi. They explore the implications of this decision for patients and providers, the role of pharmacy benefit managers (PBMs) in healthcare, and the ongoing advocacy efforts to ensure access t...

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In this episode of the Dr. Lift podcast, hosts Dr. Spencer Nadolsky and Dr. Karl discuss the Surpass CVOT trial, which evaluates the cardiovascular outcomes of Monjaro compared to Dulaglutide (Trulicity). They delve into the significance of the trial, the implications of the results, and the potential benefits of Monjaro for patients with type 2 diabetes and cardiovascular risks. The conversation highlights the importance of unders...

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How the STEP-UP trial came to life,  and what made the 7.2mg dose possible

What the data actually says about weight loss and side effects at higher doses

Why trial design, pharmacokinetics, and estimands matter more than you think

What’s coming next in obesity meds: duals, triples, and even antagonists

The real talk on intermittent fasting, access issues, and preaching vs. science

Sign up for Dr. Spencer''s Clinic

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July 2, 2025 31 mins

Takeaways

  • The study examines the overlap between clinical and anthropometric obesity.
  • Anthropometric measures include waist circumference, waist-to-hip ratio, and BMI.
  • Challenges exist in applying the Lancet Commission's definitions in clinical practice.
  • Metabolically healthy obesity is a debated topic in obesity research.
  • The study highlights the importance of data from the All of Us Research Program.
  • There is a significant prevalen...
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June 23, 2025 33 mins

Learn what age-related macular degeneration (AMD) is

What causes AMD

The types of AMD

The update on NAION - listen to last year's podcast all about it

Why we aren't too concerned

Click here to join Dr. Spencer's online clinic Vineyard

Click to read the JAMA AMD article

Click to read the Ophthalmology journal AMD article

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June 12, 2025 27 mins
  • Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopause
  • Weight management in women is influenced by hormonal changes throughout life stages.
  • Retrospective analyses can provide insights but have limitations.
  • The wellness industry often oversimplifies complex medical issues.
  • Hormonal replacement therapy may have subtle benefits for weight management.
  • Confounding factors like SSRIs can co...
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Takeaways:

  • The MAHA report aims to address public health issues but lacks actionable policies.
  • Historical context is crucial for understanding current dietary guidelines.
  • Funding for nutrition research has been inadequate, impacting the quality of data.
  • Public perception of nutrition often outpaces scientific evidence.
  • The evolution of dietary guidelines reflects political and social influences.
  • There is a need for more rigorous nutr...
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May 13, 2025 46 mins

Click to read Joy Prescriptions

Drs. Karl and Spencer talk to Dr. Tiffany Moon all about Joy Prescriptions. Learn how to stop chasing perfection and embrace connection. 

00:00Introduction to Dr. Tiffany Moon

02:02Journey to Reality TV: The Real Housewives of Dallas

05:58Life After Reality TV: Finding Joy and Purpose

09:59The Joy Prescription: A New Approach to Life

17:01Work-Life Integration: Balancing Career and Family

22:09Empowering Wo...

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May 12, 2025 20 mins
  • Tirzepatide is more effective for weight loss than semaglutide.
  • Cost-effectiveness is crucial in prescribing weight loss medications.
  • Patients with severe obesity should receive more expensive medications for better outcomes.
  • Both medications show significant benefits for obesity-related conditions.
  • Long-term studies indicate sustained weight loss with both drugs.
  • Gender differences affect weight loss outcomes with these medications...
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Takeaways

  • MASH is a significant obesity-related complication.
  • Semaglutide shows promise in treating MASH.
  • Weight loss is crucial for improving liver health.
  • Bariatric surgery remains the most effective treatment.
  • The Essence trial indicates a 63% resolution of NASH.
  • New medications are being developed for obesity treatment.
  • Early intervention is key to preventing severe liver damage.
  • Accessibility of medications is a major concern.
  • Comp...
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April 25, 2025 36 mins

Drs. Karl and Spencer chat with return guest Dr. Lauren Semple about creatine, protein, cortisol, fasting exercise, and training in women.

Follow Dr. Lauren's instagram

Join Dr. Spencer's online clinic

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April 11, 2025 25 mins

Drs. Karl and Spencer discuss a new study looking at tirzepatide and metabolic rate. They also discuss a patient case of tirzepatide induced anhedonia.

Here is the tirzepatide study

If interested in joining Dr. Spencer's clinic Vineyard - Click Here

 

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March 19, 2025 25 mins

Drs. Karl and Spencer discuss the claim that GLP-1 meds cause more fat cells.

Learn about if and how GLP-1 meds increase fat cells and what that means along with other claims about these medicine.

Join Dr. Spencer's online clinic that specializes in GLP-1 medicines

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March 11, 2025 23 mins

Drs. Karl and Spencer talk to Dr. Kenneth Qiu all about direct medical care - the future of medicine.

Learn about how bypassing insurance and creating a relationship directly with a doctor can improve your health and save money in the long run.

Follow Dr. Qiu on Linked in

See Dr. Spencer's direct care model with Vineyard

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Drs. Karl and Spencer discuss with Dr. Grant Tinsley all about the new analysis of how much "lean mass" is lost with tirzepatide, the most powerful medicine available for weight loss.

Learn:

The difference between fat free mass and lean mass and lean soft tissue and muscle.

If GLP-1 medicines cause muscle loss specifically

How to minimize muscle loss when taking these medicines

Our new study together.

Click here for the tirzepatide paper

...

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February 17, 2025 25 mins

Drs. Karl and Spencer discuss how bad the Hims and Hers ad was.

From an outside perspective, the ad may have seemed good.

But when you dig deeper, it was actually really bad.

Listen to learn.

Join Dr. Spencer's new online clinic - Vineyard.

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February 12, 2025 38 mins

Drs. Karl and Spencer chat with NMN and NAD expert Dr. Charles Brenner all about these supposed longevity supplements.

Learn about NAD metabolism

Whether it's worth supplementing or not with NAD or NMN

Follow Dr. Brenner on Twitter

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