Progress, Potential, and Possibilities Podcast / Show
Interviews and Discussions With Fascinating People Who are Creating A Better Tomorrow For All Of Us - Host - Ira S. Pastor
Episodes
Nuclear power has a scale problem: conventional plants are enormous, expensive projects that can take years to build. Hadron Energy wants to take a different approach with a factory-manufactured, 10-megawatt light-water microreactor. But can a smaller reactor actually mean lower costs, simpler deployment and credible safety?
Sam Gibson is Founder and CEO of Hadron Energy ( https://www.hadronenergy.com/ ...
The world doesn't have a shortage of promising medical discoveries. The real challenge is turning those discoveries into safe, effective, accessible treatments. What separates a breakthrough idea from a successful therapy? How could AI change the economics of drug development? And can regenerative medicine move healthcare beyond managing disease toward restoring damaged tissue? Today, we're tackling these questions ...
What if we stopped thinking about antibodies as simply drugs that bind to one target - and started thinking about them as engineered molecular machines? Today we're talking about a bispecific antibody that targets both EGFR and LGR5, and asking whether that kind of antibody engineering could actually change the treatment landscape for head and neck cancer.
Dr. Tahamtan Ahmadi, MD, Ph.D. is Executive Vice Pres...
What happens when you're 19 years old, physically fit, a collegiate wrestler, and you suddenly find yourself hospitalized for three days with influenza? Today's guest, Zachery Lang, experienced exactly that - and his story offers an important perspective on a disease many of us underestimate.
Zachery Lang ( https://familiesfightingflu.org/family-story/the-lang-family/ ) is a student at Indiana University and ...
Homelessness, addiction, mental health, aging and incarceration are often treated as separate problems. But for the people experiencing them, they're frequently connected. What would it take to build a system that sees the whole person - and could emerging technology help us get there?
Ericka Fusilier is Executive Vice President of External Affairs at VOA ( https://www.voa.org/ - formerly known as...
What if the next breakthrough in diabetes treatment isn't necessarily a new drug molecule, but a better way to deliver the drugs we already have? One biotechnology company is developing a platform designed to target the liver with insulin - and exploring whether the same principle could eventually apply to GLP-1 and other metabolic therapies. Today, we're exploring the science, the clinical evidence, and what still ...
Cancer medicine is advancing rapidly. But are patients getting the tests and treatments they need to benefit from those advances?
Chronic lymphocytic leukemia, or CLL, is one of the most common forms of adult leukemia. And while advances in targeted therapies have transformed the treatment landscape, a critical question remains: Are patients actually getting access to the right tests, the right treatments, an...
The brain is one of the most complex systems in biology, and understanding it requires more than a picture of its anatomy. We need to understand its connections, activity, and response to injury.
Today we're going to ask a fascinating question: Can advanced neuroimaging and artificial intelligence give us a much better understanding of what happens to the brain after injury and disease - and ultimately ...
We usually assume that before we can use electricity somewhere, we need to build the infrastructure to deliver it. But what if we could bring the energy infrastructure to the location instead? That's the idea behind Beam Global's approach to solar-powered EV charging, energy storage, and resilient power.
Desmond Wheatley is President, CEO, and Chairman of the Board of Beam Global ( https://beamforall.com/ ), ...
A drug can look promising in the laboratory and still fail when it reaches human testing. One of the biggest challenges in drug development is predicting what a compound will actually do inside the human body - including whether it will cause dangerous side effects. Could AI help us make those predictions more accurately, before patients are ever exposed?
Dr. Natalie Ma, Ph.D. is Chief Business Officer and a ...
What happens when your ADHD medication wears off, but your day isn't over? Homework, family responsibilities, relationships, and everything else still demand your attention. So why are we still thinking about ADHD treatment in terms of the school day or the workday? Today, we're exploring whether a different approach to drug delivery could change that.
Today we're going to take a fascinating look at ADHD trea...
What if a promising drug fails a clinical trial not because the drug doesn't work, but because it works for a subset of patients whose response gets lost in the averages? What if AI could help us find those patients hidden inside the data? That's the challenge we're exploring today with mathematical scientist Dr. Joseph Geraci, Ph.D., co-founder and chief technology and science officer at NetraMark ( https://www.net...
We've been automating laboratories for decades. Robots can pipette, instruments can run assays, and computers can analyze enormous datasets. But that's not necessarily an autonomous laboratory.
The really interesting question is: what happens when the system itself can decide what experiment should come next?
AI proposes. Robots execute. Instruments measure. The data goes back into the model - and the ...
What if you could treat a genetic disease without actually fixing the defective gene?
That's the fascinating idea behind a new approach being developed for devastating pediatric lysosomal storage disorders. These diseases can have completely different genetic causes - but ultimately disrupt some of the same cellular machinery.
So instead of trying to correct every individual mutation, could we enhance ...
Cancer treatment can save a patient's life - but what happens when the treatment itself leaves them struggling with pain, fatigue, weakness, limited mobility, or other lasting physical effects? Cancer rehabilitation is changing how we think about recovery, helping patients prepare for treatment, maintain their function, and regain their independence.
Cancer treatment has made remarkable advances, dramatically...
We have some of the most powerful AI systems in history - but what if one of the biggest obstacles to using AI to solve biology isn't the algorithms? What if it's the data?
There are enormous amounts of biological data sitting inside pharmaceutical companies, biotech companies and research institutions. The problem is that much of it is proprietary - and the organizations that spent millions generating it hav...
What if we could look inside the breast without X-rays, without compression, and without injecting a contrast agent - and instead use sound to create a three-dimensional map of the tissue?
Dr. Raluca Dinu, Ph.D. is Chief Executive Officer of QT Imaging ( https://www.qtimaging.com/ ), a medical technology company developing quantitative, three-dimensional breast imaging using transmission and reflection ultras...
There are tens of millions of Americans quietly caring for a parent, spouse, child or loved one - often while trying to maintain a career and a normal life. Yet much of that work is essentially invisible to our healthcare system, our economy and even our data infrastructure.
Richard Lui ( https://richardlui.com/ ) is an award-winning journalist, filmmaker, author, entrepreneur, and nationally recognized careg...
A robot can see you.
It can recognize you.
It can track where you're moving.
But can it understand what you're trying to do?
Because humans don't simply move through the world - we constantly interpret one another's intentions, expectations, emotions and behavior.
And as AI-powered robots move from factories into restaurants, hospitals, hotels, stores and eventually our homes, that...
Your face can now be turned into a mathematical representation, searched against enormous databases, and potentially matched in fractions of a second. But what happens when AI moves beyond recognizing your face - and starts understanding everything happening around you?
B. Scott Swann is CEO of ROC ( https://roc.ai/ ), formerly known as Rank One Computing, a company developing AI-powered biometric identity, v...
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