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March 17, 2025 54 mins

In 1958, Dr Denis Burkitt was working in Uganda when he saw multiple children with large and aggressive jaw tumours. He had never seen anything like this before and he investigated further. Over the next few years, he discovered that these tumours had a geographical distribution across equatorial Africa and also was related to rainfall.

This led to the discovery of an aggressive form of lymphoma that we now know as Burkitt lymphoma as well as the Epstein-Barr virus (EBV). It is a remarkable story of intellectual curiosity, scientific discovery, and commitment.

Éanna Mac Cana was diagnosed with Burkitt lymphoma in 2017. This diagnosis led him to the story of Dr Denis Burkitt and how we first learned about this disease. He has created a documentary using never-before-seen archival footage of Dr Denis Burkitt and his discovery, and included his own journey with this disease.

This is the story of Burkitt lymphoma.

Our special guests include:

Éanna Mac Cana who is a documentary filmmaker from Belfast in Ireland.

Professor Jonathan Bond from the University College Dublin and works in paediatric molecular haemato-oncology.

This Medical Life podcast is available on all podcasting services and Spotify.

See omnystudio.com/listener for privacy information.

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