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July 23, 2025 154 mins
Demis Hassabis is the CEO of Google DeepMind and Nobel Prize winner for his groundbreaking work in protein structure prediction using AI. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep475-sc See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: https://lexfridman.com/demis-hassabis-2-transcript CONTACT LEX: Feedback - give feedback to Lex: https://lexfridman.com/survey AMA - submit questions, videos or call-in: https://lexfridman.com/ama Hiring - join our team: https://lexfridman.com/hiring Other - other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: Demis's X: https://x.com/demishassabis DeepMind's X: https://x.com/GoogleDeepMind DeepMind's Instagram: https://instagram.com/GoogleDeepMind DeepMind's Website: https://deepmind.google/ Gemini's Website: https://gemini.google.com/ Isomorphic Labs: https://isomorphiclabs.com/ The MANIAC (book): https://amzn.to/4lOXJ81 Life Ascending (book): https://amzn.to/3AhUP7z SPONSORS: To support this podcast, check out our sponsors & get discounts: Hampton: Community for high-growth founders and CEOs. Go to https://joinhampton.com/lex Fin: AI agent for customer service. Go to https://fin.ai/lex Shopify: Sell stuff online. Go to https://shopify.com/lex LMNT: Zero-sugar electrolyte drink mix. Go to https://drinkLMNT.com/lex AG1: All-in-one daily nutrition drink. Go to https://drinkag1.com/lex OUTLINE: (00:00) - Introduction (00:29) - Sponsors, Comments, and Reflections (08:40) - Learnable patterns in nature (12:22) - Computation and P vs NP (21:00) - Veo 3 and understanding reality (25:24) - Video games (37:26) - AlphaEvolve (43:27) - AI research (47:51) - Simulating a biological organism (52:34) - Origin of life (58:49) - Path to AGI (1:09:35) - Scaling laws (1:12:51) - Compute (1:15:38) - Future of energy (1:19:34) - Human nature (1:24:28) - Google and the race to AGI (1:42:27) - Competition and AI talent (1:49:01) - Future of programming (1:55:27) - John von Neumann (2:04:41) - p(doom) (2:09:24) - Humanity (2:12:30) - Consciousness and quantum computation (2:18:40) - David Foster Wallace (2:25:54) - Education and research PODCAST LINKS: - Podcast Website: https://lexfridman.com/podcast - Apple Podcasts: https://apple.co/2lwqZIr - Spotify: https://spoti.fi/2nEwCF8 - RSS: https://lexfridman.com/feed/podcast/ - Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 - Clips Channel: https://www.youtube.com/lexclips
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