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November 24, 2025 16 mins

From Easter Island soil to modern skin science — meet rapamycin, the molecule that might just change vitiligo care.

Once known mainly as an anti-rejection drug for organ transplants, rapamycin is now being tested as a topical treatment that could both calm the immune attack and help pigment return. Early studies look promising: minimal side effects, slow but steady repigmentation, and surprisingly good tolerance.

In this episode, we explore:

  • How rapamycin rewires the skin’s immune balance
  • Why it’s called both a suppressor and a rejuvenator
  • What Phase II trials are revealing so far
  • And whether this “longevity drug” might also restore color to the skin

It’s too early to call it a breakthrough — but this little molecule from a far-off island might just be the next quiet revolution in vitiligo therapy.

Full story: Topical Rapamycin: Could This Be Vitiligo’s Next Big Breakthrough?

 

 

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