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November 18, 2025 22 mins
The Cult of the Needle: Why Everyone’s Injecting Everything — and Why You Don’t Need To

In this episode of Midlife Mayhem, Joanne dives into one of the wildest cultural shifts in modern health and fitness: how we went from terrified of needles to injecting everything in sight — from weight loss medications to peptides, and now, even experimental compounds.

A few years ago, the idea of self-injecting anything was unthinkable. Today? People proudly post their peptide stacks like they’re Michelin-star meals. But somewhere in all this newfound syringe enthusiasm, we’ve lost sight of something important: the delivery system doesn’t determine the result — the mechanism does.

💉 Inside This Episode

This is a deep, science-backed, myth-busting conversation for anyone curious about:

  • Why injectable doesn’t automatically mean superior

  • The real reason scientists use injections in research — and why that doesn’t translate to better human results

  • How 5-Amino-1MQ and SLU-PP-332 actually work at the cellular level

  • The difference between spikes and stability in metabolism and fat oxidation

  • How oral delivery can often outperform injections by providing consistent activation instead of biochemical chaos

  • Why small, lipophilic molecules like 5-Amino-1MQ and SLU-PP-332 thrive in oral form — and what that means for energy, endurance, and longevity

  • The hidden risks of home-mixed injectables (purity, solvents, contamination, degradation)

  • Why consistency, not intensity, is what drives results in body composition and performance

🧠 The Takeaway

Injectables look hardcore. They feel scientific. But for many compounds — especially small molecules designed to work through long-term cellular signaling — oral delivery isn’t a compromise. It’s often the smarter, safer, and more sustainable route.

The body doesn’t care how fast something hits your bloodstream; it cares how well it integrates into your system. And that’s where the hype ends and the science begins.

⚡ Key Quotes

“Injectables were designed for lab control, not lifestyle performance.”

“Needles spike. Capsules sustain. And for long-term results — stability wins.”

“We’ve glamorized the syringe, but metabolism doesn’t need theater — it needs consistency.”

🧬 Want to Learn More?

Explore the science, studies, and benefits behind these two groundbreaking compounds: 👉 www.5amino.com — Learn about 5-Amino-1MQ and how it supports metabolism, energy, and muscle preservation. 👉 www.slu332.com — Discover SLU-PP-332, the endurance molecule known as “exercise in a bottle.”

And for more in-depth discussions on midlife performance, muscle, and metabolism: 🎥 Subscribe to my YouTube channel — @JoanneLeeCornish

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