Midlife Mayhem

Niacinamide, Amino Acids, and Why Source Confusion Doesnt Matter

In today’s episode, Joanne dives into two simple, misunderstood products — one for skin and one for muscle — and explains why what something does matters far more than where it comes from.

This is a practical, science-backed conversation about cellular biology, not marketing hype.

 

MUSCLE MONTH STARTS IN LESS THAN 2 WEEKS!  www.musclemonth.com

✨ PART 1 — NIACINAMIDE...

Energy Drinks, Gut Damage, Gallbladders… and Why Women Shouldn’t Train Like Men

In today’s episode I cover two topics that came up in real conversations this week: energy drinks (especially in teens/20s) and a key Muscle Month training concept most people get wrong.

Energy drinks: what’s the big deal?

A client told me her doctor is seeing more gallbladder issues in young people, plus signs of gut lining irritation — and energy drin...

Midlife Mayhem — Thyroid, Testosterone & Metabolism in Midlife

In this episode of Midlife Mayhem, I’m talking about thyroid and testosterone — two topics I’ve covered before, but ones that came up for me personally this week in a way that highlights just how misunderstood midlife physiology still is.

I was diagnosed with hypothyroidism over 15 years ago, and for me it was never just about weight. It showed up as fatigue, cold i...

Episode Theme: Stop Obsessing Over Details — Create the Right Environment

This episode was recorded fresh off my first Peak Week coaching call of the year, and something really stood out: People aren’t failing because they’re lazy or unmotivated — they’re stuck because they’re overthinking details instead of creating the right environment.

This episode is about simplifying results by focusing on conditions, not perfection.

The Cor...

🚀 Work With Me in 2026

Everything is now in one place:

👉 https://www.joannelee.com

You’ll find:

• My full program schedule

• 90-Day Elite 1:1 Coaching

• Perfect Ten — a 10-month immersive mentorship, limited to 10 women only

🔐 Coming up next: The Victory Vault — January 26 to February 7 A two-week live coaching program I’m genuinely looking forward to coaching. I’ve got a few things I want to tighten up for 2026, and ...

🎙️ Energy: Why You’re Tired, What Actually Makes Energy — and What Really Works

I am just fine-tuning all the pages of my new website but it is live www.joannelee.com on there you will find the online coaching schedule for 2026, the one on one 90 Day Coaching Program and the 10 month Mentorship Program - A Perfect Ten

The products mentioned in this podcast can also be found at www.joanneleestore.com and the video version of this p...

Welcome to 2026 — and yes, I tried to turn this podcast into video… and of course it wasn’t simple. 🙃 The video version is still happening (YouTube: Joanne Lee Cornish) — but for now, it’s you, me, and my English accent.

The Peak Week 5 Day Shred starts on Monday, yes THIS Monday - offered only once a year!

Today’s Topics 1) The quiet truth about change

You don’t hate your life… but you’re not really happy either. Thinking about c...

🎙️ Episode Notes: The Habit Formation Curve — Why It Gets Hard Before It Gets Easy

In this episode, we break down why habits feel hardest right before they actually stick — and why so many people quit at exactly the wrong moment.

Most of the anxiety around goals, body composition, or behavior change doesn’t come from lack of effort. It comes from not understanding how habit formation actually works.

I introduce a concept known as ...

Exercise as a Tool: Cardio, Bias, and What Actually Works

Exercise is a tool — and we’ve used it very differently over the decades.

Think about it: In the 1950s, “exercise” wasn’t really a thing the way it is now. People moved, they danced (my parents and grandparents were ballroom dancers), but it wasn’t packaged as “workouts.”

Then we got the eras:

• 70s/80s/90s: jogging + long, steady-state cardio

• 2000s: long-duration card...

🎙️ Can You Train With Osteoporosis? Running, Bone Strength & Why Calcium Alone Doesn’t Work

Recorded on Christmas Eve 🎄

Before we dive in, I want to wish you a very Merry Christmas. Wherever you’re listening from, take a moment to look around and be grateful for what’s right in front of you. I’m incredibly grateful for all of you who listen to this podcast — it started as an extension of Victory Vault and is now heading into ...

☕ Adenosine, Coffee & Why Tiredness Is Supposed to Happen

Midlife Mayhem Podcast

It’s Christmas week 🎄 and just a few weeks until my programs begin for the new year. If you’d like to see my full 2026 schedule, you’ll find it at:

👉 www.JoanneLee2026.com

🚀 Programs Starting Soon 5-Day Peak Shred

📅 January 12–18

A powerful 5-day reset with:

• Coaching calls

• Structure

• Momentum

• Yes, weight loss — but so much more than...

In this episode, Joanne connects several conversations that are often discussed separately — facial fat loss, muscle loss, grip strength, hormones, and rapid weight loss — and explains why they’re all part of the same biological picture in midlife.

Rather than treating these changes as isolated or cosmetic issues, this episode explores what’s really happening underneath: estrogen decline, rising myostatin, changes in muscle quality...

What Compounding Pharmacies Actually Do — Why December 31st Matters — and the GLP-1 Confusion Explained

Before we talk about December 31st, the FDA, or compounded weight-loss medications, this episode starts with something most people misunderstand:

What compounding pharmacies are actually for.

Joanne begins by explaining the original and ongoing role of compounding pharmacies — using hormone replacement therapy (HRT) as a clear, l...

Today’s episode was sparked by a Medscape article that immediately grabbed my attention. The headline essentially said that set point weight does not seem to decrease with the use of GLP-1 medications.

If you’re taking Semaglutide, Tirzepatide, or any of the current weight-loss medications, that line alone is enough to make your heart skip a beat. For many people, these medications have felt like the first time in their lives that ...

Testosterone therapy is exploding in popularity, especially among midlife women — but how you take testosterone dramatically affects how it works in your body.

In this episode, Joanne breaks down the three major delivery systems — transdermal creams, oral lozenges, and injections — and explains why some women are now being told they’re “poor absorbers” and switched to oral or injectable forms.

You’ll learn:

• Why women may not ...

In this episode of Midlife Mayhem, Joanne breaks down one of the most misunderstood concepts in the supplement and peptide world: half-life — the amount of time it takes for half of a substance to leave your system.

Half-life is the key that determines:

• how often you should take something

• whether a pill works better than an injection

• why weekly injections make sense for some compounds

• and why weekly injections are compl...

🔍 Episode Overview

Joanne Lee Cornish explores two massive wellness categories — green powders and fiber supplements — breaking down real science, real efficacy, and real value. She helps you make informed decisions, avoid marketing fluff, and invest in what actually works.

🧬 What You’ll Learn

• The manufacturing differences between whole-plant powders, juice powders, and cheap heat-dried powders

• Why processing method deter...

🎙 SHOW NOTES — “PCOS Doesn’t End at 30: The Midlife Metabolic Storm No One Warned Us About”

Most women only hear about PCOS in their teens or twenties — when cycles are irregular, acne is flaring, weight is piling onto the midsection, and fertility becomes a concern. But here’s the truth:

👉 PCOS does NOT disappear. 👉 Symptoms simply shift. 👉 And midlife can amplify everything that was simmering beneath the surface for decades.

...

The Cult of the Needle: Why Everyone’s Injecting Everything — and Why You Don’t Need To

In this episode of Midlife Mayhem, Joanne dives into one of the wildest cultural shifts in modern health and fitness: how we went from terrified of needles to injecting everything in sight — from weight loss medications to peptides, and now, even experimental compounds.

A few years ago, the idea of self-injecting anything was unthinkable. Today?...