Season 1: The Science of Aging | Episode 8: Mitochondria & Mitophagy
Embark on an enlightening journey as we unravel the intricate dynamics of mitochondria, our cellular powerhouses, and their role in the aging process. In this episode, we delve deep into the phenomenon of mitophagy, a vital quality control process, and explore the profound implications of reactive oxygen species (ROS) in cellular adaptation. We also dissect the age-related decline of NAD+, a pivotal coenzyme, and its links to mitochondrial function and overall cellular health.
Join us as we critically examine the latest scientific research, discussing the potential and limitations of NAD+ boosters like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN). We also venture into emerging compounds such as taurine and alpha-ketoglutarate (AKG), assessing their roles in extending healthspan and combatting age-related decline.
Moreover, discover the undeniable power of exercise as a mitochondrial elixir, fostering both biogenesis and effective mitophagy. Learn about smart training strategies and how to implement periodized training to maximize mitochondrial health. We provide detailed insights into the biomarkers that help measure mitochondrial power and quality, offering a toolkit for personal health optimization.
This episode goes beyond the hype, navigating the complex interplay between lifestyle, nutrition, and emerging scientific innovations. It delivers actionable takeaways for enhancing your resilience and energy at a cellular level, providing a clearer understanding of the central role mitochondria play in unlocking a vibrant, lasting healthspan. Equip yourself with the knowledge to critically evaluate new health interventions and forge a path toward thriving at any age.
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Ruthie's Table 4
For more than 30 years The River Cafe in London, has been the home-from-home of artists, architects, designers, actors, collectors, writers, activists, and politicians. Michael Caine, Glenn Close, JJ Abrams, Steve McQueen, Victoria and David Beckham, and Lily Allen, are just some of the people who love to call The River Cafe home. On River Cafe Table 4, Rogers sits down with her customers—who have become friends—to talk about food memories. Table 4 explores how food impacts every aspect of our lives. “Foods is politics, food is cultural, food is how you express love, food is about your heritage, it defines who you and who you want to be,” says Rogers. Each week, Rogers invites her guest to reminisce about family suppers and first dates, what they cook, how they eat when performing, the restaurants they choose, and what food they seek when they need comfort. And to punctuate each episode of Table 4, guests such as Ralph Fiennes, Emily Blunt, and Alfonso Cuarón, read their favourite recipe from one of the best-selling River Cafe cookbooks. Table 4 itself, is situated near The River Cafe’s open kitchen, close to the bright pink wood-fired oven and next to the glossy yellow pass, where Ruthie oversees the restaurant. You are invited to take a seat at this intimate table and join the conversation. For more information, recipes, and ingredients, go to https://shoptherivercafe.co.uk/ Web: https://rivercafe.co.uk/ Instagram: www.instagram.com/therivercafelondon/ Facebook: https://en-gb.facebook.com/therivercafelondon/ For more podcasts from iHeartRadio, visit the iheartradio app, apple podcasts, or wherever you listen to your favorite shows. Learn more about your ad-choices at https://www.iheartpodcastnetwork.com
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com