S1E08 - Mitochondria & Mitophagy

Season 1: The Science of Aging | Episode 8: Mitochondria & Mitophagy

Embark on an enlightening journey as we unravel the intricate dynamics of mitochondria, our cellular powerhouses, and their role in the aging process. In this episode, we delve deep into the phenomenon of mitophagy, a vital quality control process, and explore the profound implications of reactive oxygen species (ROS) in cellular adaptation. We also dissect the age-related decline of NAD+, a pivotal coenzyme, and its links to mitochondrial function and overall cellular health.

Join us as we critically examine the latest scientific research, discussing the potential and limitations of NAD+ boosters like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN). We also venture into emerging compounds such as taurine and alpha-ketoglutarate (AKG), assessing their roles in extending healthspan and combatting age-related decline.

Moreover, discover the undeniable power of exercise as a mitochondrial elixir, fostering both biogenesis and effective mitophagy. Learn about smart training strategies and how to implement periodized training to maximize mitochondrial health. We provide detailed insights into the biomarkers that help measure mitochondrial power and quality, offering a toolkit for personal health optimization.

This episode goes beyond the hype, navigating the complex interplay between lifestyle, nutrition, and emerging scientific innovations. It delivers actionable takeaways for enhancing your resilience and energy at a cellular level, providing a clearer understanding of the central role mitochondria play in unlocking a vibrant, lasting healthspan. Equip yourself with the knowledge to critically evaluate new health interventions and forge a path toward thriving at any age.