Episode Transcript
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Welcome to Body In Balance Podcast.
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I am your host, Charlotte Johnson.
The Certificate Licensed Physician Assistant sent here to kick some knowledge your way,
once a week, for the purpose of educating, informing, and enlightening this audience
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concerning physical, spiritual, and emotional aspects of our bodies in relation to our Creator.
The one, the only, the true and living God, yes, yes, He is the King of kings.
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I'm the Lord of Lords.
Let us give it up for Yahweh.
Hello there.
Hello there.
Hello there.
I'm excited.
I'm excited today.
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We're going to be talking about the new medications out there for weight loss.
We're going to be talking about obesity and the transformation with GLP-1 medications.
Let's get started because there's a lot of great information that I'm going to be sharing
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some slides for you all to watch and get into that will give you more information right away.
All right.
So our agenda for today's lesson is going to be we're going to reiterate the importance
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of movement that we talked about in episode six because that was very helpful on making
sure that you understood how important it is to increase your circulation, to maintain
strength and to maintain flexibility and movement.
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The importance of our pancreas.
Wait a minute.
Who thinks about their pancreas?
We talk about our brains.
We talk about our hearts.
But our pancreas?
Well, you watch.
You'll see how important that pancreas is to you.
Diabetics know! The third thing we're going to be getting into is how these new GLP-1 medications
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work.
People you need to understand what you're putting in your body.
You've got to understand how does it help?
How does it make you better?
What is it doing?
What effect does it have?
We're going to talk about that.
And we're also going to be talking about the benefits and the risks of medications.
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Part of what we're going to be doing is understanding the importance of the renewing
of our mind, the transforming of our minds.
We have to be able to understand the importance of transforming our minds, thinking a different
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way, thinking of your body as a temple.
You've got to understand the importance of thinking of your body as a temple because
you're going to take care of it in such a way.
So short walks.
You remember we talked about this in our last episode.
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We talked about not driving around in the grocery store parking lot, the mall parking
lot for two minutes, three minutes, trying to get a parking spot close.
In the back, if God has blessed you to have the activity of your limbs, use them.
Walk.
Get that exercise.
You see those stairs?
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You see the elevator.
Use the stairs.
Two flights of steps is not going to hurt you.
That's going to be good.
It's going to strengthen your limbs.
It's going to exercise your heart and invigorate your circulatory system.
You want to do that.
Your exercise is important.
Yoga, Pilates, stretching, flexibility, going to planet fitness or any of these other gyms
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for strengthening and weight.
Let me tell you something about planet fitness.
It's a really great place because they have trainers.
They have massage, hydro massages.
It's a lot of great stuff that goes with having a gym membership with planet fitness.
Now, I go there, but I have no other skin in the game with them.
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Getting it in.
Yes, we want to get it in.
We want to get that exercise in.
I put in a few little things that you can look at.
These are mini little bikes that you can stick under your desk.
They go up to as expensive as $120 to $130, but I got a mid-range price for $86.
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There's one for $38 if you're on a little bit thinner budget.
Then, there is the Thuriband.
I talked to you all about that for flexibility and for strengthening.
It gives you resistance.
That is only $13.
You can hook it onto a chair in your office and use it to strengthen your shoulders, your
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arms.
You can pull your arms apart.
As you're pulling your arms apart, while you have that on your wrist, it tends to strengthen
your shoulders back, upper back, and up.
Now, let's talk about the importance of our pancreas.
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This gland has two functions.
It's the digestive function, and then it has an excrein function.
When it's an excrein gland, it releases digestive enzymes to break down proteins, carbohydrates,
and fats.
When it acts as an endocrine gland, it regulates our blood sugars, whether your blood sugar
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is too low or too high.
If it's too high, it's because you don't have enough insulin.
If it is too low, it's because you don't have enough glucose.
Glucogon is released to start to control that glucose.
I'm going to jump back and minimize this.
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I'd love to show you all a video.
I'm going to do that right now.
I'm going to show a video clip on the anatomy of the pancreas.
The role and anatomy of the pancreas.
The pancreas is an important organ in the digestive system.
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It is located in the upper abdomen, directly behind the stomach, and next to the small intestine.
In most adults, it is between 6 and 10 inches long and 2 inches wide.
The pancreas is comprised primarily of a network of tubes or pancreatic ducts that release
liquids into the upper portion of the small intestine, called the duodenum.
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Anatomically, the pancreas is divided into three regions, the head, the body, and the
tail.
The pancreas has two functions, endocrine and exocrine.
This endocrine function is to produce the chemicals or hormones that regulate blood
sugar, such as insulin.
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Its exocrine function is to produce enzymes that help to digest food.
Pancreatic amylase breaks down carbohydrates or starches into glucose.
Proteases break down protein into amino acids, and lipases break down fats.
Because these digestive enzymes are so powerful, they are wrapped in a protective layer while
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they are in the pancreas.
To reach the gastrointestinal tract, the digestive enzymes travel through the pancreatic ducts
and are eventually released into the duodenum at the major papilla, also known as the ampola
of Vader.
Once they are completely out of the pancreas, the protective layer is removed and the enzymes
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become active.
All from the gallbladder also enters the duodenum at the major papilla.
Bio breaks apart fat into smaller fat droplets, which are easier for lipase to digest.
When the pancreas is healthy, it contributes to a healthy digestive system.
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However, when our pancreas does not function correctly and is unwell, we can have trouble
digesting food properly or maintaining our blood sugar in a healthy range.
The consequences of an unwell pancreas may include diarrhea, bloating, flatulence, oily
and foul-smelling stool, weight loss, malnutrition, poor blood sugar control, and diabetes.
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Heavy alcohol consumption, high-fat diets, eating large meals, being overweight, and
tobacco products can put stress on your pancreas, causing it to work less well.
There are also some genetic conditions that affect the pancreas, notably cystic fibrosis.
To help keep your pancreas healthy, eat a varied diet that is rich in fruits and vegetables.
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Include fish and white meats as favored sources of protein.
Limit high-fat foods and alcohol to special occasions.
Take a healthy weight and watch your cholesterol and triglyceride levels.
Alright, so that was a short little video talking about the things that I just talked
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to us about.
Now we're going to start talking about the GLP-1 weight loss medications.
We're going to just talk about these two, simba-glutide and terzepotide.
Simba-glutide was out there first, and it was discovered as a diabetic medication.
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It was called ozympic.
So ozympic was out first, and in its trial, let me tell you something about new medications.
All new medications, once they go through testing and evaluations and trials, then they
come to the market and they go through the FDA.
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They go through the FDA, they get approved, and then all the people that use those medications,
when drug reps come to your doctor's office and give samples, they're giving those samples
for you to try that medication.
Your doctor talks to you about using those medications, and now you are in a trial.
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You are in a trial to see how these things work.
You know what happened?
People were using ozympic, and they were noticing that patients that were overweight but had
hemoglobin A1Cs over 6.5 that were using the ozympic lost a lot of weight.
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So then they started investigating the medication even the more.
When they did, they decided to make another medication called Wigovie.
Wigovie is the same exact medicine as ozympic.
Now we're getting into the business part of medications.
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Ozympic was for diabetics, and insurance companies would pay for that.
Wigovie, if you did not have or do not have a hemoglobin A1C over 6.5, making you clinically
a diabetic, then you could not use the ozympic.
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So they had to give you Wigovie.
That would distinguish you from the diabetic patient that was going to get the medication
for weight loss.
So it's used as weight loss, but doctors have strict criteria to only give it to those that
have BMI's over 30 and hemoglobin A1Cs under 6.5.
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Then you have to use Wigovie, which is a way for the insurance company to weed you out
so they don't have to pay for the medication.
That's what that issue is about.
So now what goes on is terzepotide started to make its own medication called Majorno.
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Majorno is strictly a weight loss medication.
It works the same way as these other GLP medications.
I'm getting ready to show you a little video on how the GLP1 medication works in the body.
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GLP stands for glucagon-like peptide 1.
Now you remember in the past, the last video I showed you, there was a enzyme called glucagon.
That's a natural enzyme that is within the body, a natural hormone within the body that's
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made in the gut and in the pancreas.
Now what these medications are, they're kind of fake news glucagon.
They're glucagon-like peptides that work the same way in the gut.
So now we're going to talk about how the GLP1 works in the body.
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I'm going to show you this video now.
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Okay, so we see how it works in three different areas.
It works in the brain, in the hypothalamus.
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It works in the gut to slow the gut down.
When it works in the brain, it works on the hypothalamus and that's the area that makes
us feel sciety, sciety or fullness.
It lets you know when you've had enough people that don't have that working tend to overeat.
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So what this does is it affects that area and causes you not to overeat.
It works in the gut to slow down the digestive tract.
It works in the pancreas to produce the glucagon so that it can act like a glucagon enzyme
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that's normally in the body.
It also increases your insulin intake.
So what the glucagon does is act like an Uber driver and help to get blood sugar into the
cells, which gives you more energy.
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Let's move on.
So let's talk about risk and benefits of GLP1 medications.
Risk and benefits, so our risk for these medicines is vomiting and nausea.
When I first started taking ozympic because I am diabetic, I had a lot of nausea.
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I didn't know whether I was going to be able to continue on with the medication.
However, after about two weeks, my doc kept telling me to hang in there and after about
two weeks, it started getting better.
I've been on it over a year and it hasn't bothered me.
Now, our digestive tract is the other thing that gets affected.
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You can end up getting constipation or diarrhea.
You can also have a terrible stomach cramps and then there is the pancreas.
You can get pancreatitis.
That's a horrible, painful, painful issue where you get inflammation of your pancreas.
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Then there's kidney damage.
It is very important when you take these medications that you drink water.
If you do not like drinking water, I would not suggest that you move forward with these
medications because what they tend to do is it tends to dry out the kidney and then it
can cause damage and problems for your kidney function.
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Those of you that have medullary thyroid cancer or have had medullary thyroid cancer or a
family history of medullary thyroid cancer should never take this medicine.
That should be brought up.
If your doctor doesn't ask you about that, you need to let him know if you know that
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there is a family history of thyroid issues.
Benefits, well, the obvious benefit is what we're talking about today, weight loss.
The second thing is diabetic control.
The third thing is the increased energy levels that you can get from these medicines.
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In conclusion, one of the things I want to talk about, I'm going to bring up some questions
for you.
The first one is, if there an end to using this medication after you lose weight.
Now, my emphasis for continuing to exercise, keeping a well rounded diet and that kind
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of thing while you're on these medicines is for you to understand.
You have got to change your mindset.
You cannot want to take this medicine for a year or so, lose 50 to 60, maybe 100 pounds.
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You can lose all of that weight, but it will come right back if you continue to have the
same behavior.
You've got to change your mindset.
Think about exercising, working out, eating correctly, not eating late at night, not overeating.
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Make your portion sizes smaller.
2000 calorie diet is the appropriate diet for most adults.
If you are a young 25 and you're a construction worker, maybe a 2500 calorie diet, if you're
outside and working, then that's probably better for you.
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But for the most adults, you should eat a 2000 calorie diet with fruits and vegetables
included.
That would include your proteins.
So you need to look at changing your mindset.
Studies have not been shown.
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Remember I said what they do with these medicines is all the people that are using them, you're
in a study.
You're in a long term study.
And they don't know the effects of these medications on your body for long term use.
So a year to a year and a half, maybe two years, you want to stay on these, get off,
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lose the weight you're supposed to lose and move on by maintaining a healthy diet and
exercise program.
Number two, what are the areas of the body?
Does this medication work in?
Well, I told you your brain, the hypothalamus, the intestines and the pancreas.
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I want to go back to something real quick, the N1 of parents.
I want to speak to the parents of these children.
Six, seven, eight years old.
Stop.
Stop feeding them all this junk food.
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Stop giving them these juice boxes full of sugar that would cause them to gain weight.
These little dollar juices you get at the dollar store that are full of artificial colors
and sweeteners.
It's not good for them and it changes their brain to think that that's okay.
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And they will eat like that.
And if they eat like that, we have never had such a pandemic of obesity in our children.
They don't go outside and play like we used to play.
We used to get kicked out of the house and don't come back until the street lights come
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on.
We played soccer.
We played football.
We played tag.
We played hide and go seek.
We played marbles.
We did summer.
Everything played basketball, football, ran track, had track meets.
We rode bikes.
We did those things.
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These children now sit in front of computers.
They sit in front of TVs.
And they sit in front of their phones, tablets, and all they do is work their thumbs.
They just work their thumbs.
And so they're not exercising and moving.
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Parents, I adjure you.
Please get your children to move.
Now let's go to three.
One of the benefits of using these medications, the obvious one that we've been talking about
is weight loss.
Now in a head-to-head study, I did a lot of research on this.
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And in a head-to-head study that I saw in Johns Hopkins, a one-year period of majorno
at two milligrams, which is equivalent to the one milligram for the ozympic, you could
lose up to 15 percent, 15.3 percent of weight was lost compared to 8.3 percent on the ozympic
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or the Wagovii.
All right.
Number four, what are the risks of these medications?
Their gut problems are the most, the nausea, the vomiting, the constipation, the diarrhea,
the paincreas, which causes severe, severe pain, kidney issues, and it should not go
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unnoticed.
You've got to make sure that you don't have problems with thyroid cancers.
Those are the things that I wanted to bring up.
I hope that this has been informative for you.
I am not pushing anyone to use these medications, nor am I warning you or telling you don't
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use them.
What I am doing is giving you information so that you can have an informed decision.
You can make an informed decision on what you want to do with these medications.
I want you to understand there's not enough studies to know what long-term use of them
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are.
I wouldn't do more than two years on there, but I would make sure that I am changing my
lifestyle.
For now, again, I hope that this has been a blessing to you and has worked out for you
as something that would help you to make changes in your life.
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I want to share, you can look on the bottom of my presentation and you will see the email
address.
If you have any questions on any of our episodes, please send a question and I'll check and
get back with you.
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If I know the answer, I will get to you.
If I don't, I will research and come back or find someone that does know to be a blessing
to you.
It is my desire for you to be informed and to be blessed.
Having a healthy lifestyle and taking care of your body and keeping it in balance.
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Be blessed.