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January 31, 2025 105 mins

Have you ever wondered what your arteries are hiding? As someone who’s spent decades scanning carotid arteries and studying heart health, I’ve seen firsthand how much we miss when we only look at cholesterol numbers. In this conversation, I’m sitting down with Dr. William Cromwell, a top lipidologist, and Matthew Martin, co-founder of Precision Health Reports, to uncover the secrets your arteries could be holding—and what you can do about it.

We dive into groundbreaking imaging technology, why precision medicine is changing the game, and how small lifestyle changes can make a massive difference in preventing heart disease. I’ll also share why the moment I saw my own arterial plaque was a game-changer—and how that same wake-up call could save your life.

This isn’t just shop talk. It’s the stuff that transforms how you think about your health and gives you the tools to take control. If you’re ready to learn what’s really happening inside your body and why it matters, let’s jump in.


Key Takeaways

Understanding Carotid IMT:

  • How carotid IMT imaging helps identify early plaque buildup in arteries.
  • Why traditional risk factors like cholesterol levels might not tell the whole story.
  • The importance of measuring plaque volume, composition, and flexibility for predicting cardiovascular events.

Precision Medicine Revolution:

  • Moving from population-based care to tailored healthcare solutions.
  • How integrating clinical history, biomarkers, and non-invasive imaging can drastically improve outcomes.
  • Why personalized health reports are empowering patients and physicians alike.

The Role of Lifestyle and Risk Factors:

  • The detrimental impact of seed oils, high-fructose corn syrup, and processed foods.
  • Why metabolic health and insulin resistance are critical indicators of overall cardiovascular risk.
  • Practical advice on therapeutic lifestyle changes that can complement or even replace medication in some cases.

From Research to Real-World Impact:

  • Dr. Cromwell’s journey from academic research to co-founding Liposcience and pioneering lipoprotein analysis.
  • The story behind Precision Health Reports and how it’s transforming patient education and engagement.

Game-Changing Technologies and Concepts:

  • The potential of tools like NMR spectroscopy and advanced imaging to provide clearer insights into heart health.
  • Emerging research on natural remedies like nattokinase and fermented foods.
  • The importance of addressing systemic inflammation and promoting gut health.


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